Drosophila melanogaster

55 known processes

Sur-8 (Dmel_CG5407)

CG5407 gene product from transcript CG5407-RA

(Aliases: CG5407,Dmel\CG5407,CT17146,Sur8,SUR-8)

Sur-8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.115
negative regulation of cellular biosynthetic process GO:0031327 277 0.076
regulation of protein metabolic process GO:0051246 256 0.073
developmental growth GO:0048589 280 0.068
phosphorylation GO:0016310 294 0.066
actin filament based process GO:0030029 220 0.066
organelle assembly GO:0070925 198 0.064
response to other organism GO:0051707 293 0.063
macromolecular complex assembly GO:0065003 256 0.058
behavioral response to ethanol GO:0048149 49 0.058
neurological system process GO:0050877 358 0.057
defense response GO:0006952 300 0.056
response to bacterium GO:0009617 198 0.054
adult behavior GO:0030534 137 0.052
ion transmembrane transport GO:0034220 122 0.051
protein modification process GO:0036211 438 0.050
defense response to other organism GO:0098542 225 0.048
regulation of cellular protein metabolic process GO:0032268 243 0.048
dna metabolic process GO:0006259 227 0.047
nuclear division GO:0000280 332 0.046
tissue morphogenesis GO:0048729 297 0.046
cellular response to organic substance GO:0071310 132 0.046
intracellular transport GO:0046907 228 0.044
death GO:0016265 284 0.044
response to organic substance GO:0010033 284 0.043
positive regulation of cell death GO:0010942 69 0.043
negative regulation of rna metabolic process GO:0051253 251 0.043
posttranscriptional regulation of gene expression GO:0010608 145 0.043
negative regulation of gene expression GO:0010629 387 0.042
protein modification by small protein conjugation or removal GO:0070647 106 0.041
mitotic nuclear division GO:0007067 213 0.041
negative regulation of rna biosynthetic process GO:1902679 240 0.041
intracellular signal transduction GO:0035556 300 0.040
vesicle mediated transport GO:0016192 381 0.040
regulation of synapse structure and activity GO:0050803 128 0.040
growth GO:0040007 359 0.039
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.038
defense response to bacterium GO:0042742 178 0.038
response to heat GO:0009408 63 0.038
eye development GO:0001654 323 0.038
small molecule metabolic process GO:0044281 305 0.037
synapse organization GO:0050808 196 0.037
regulation of phosphate metabolic process GO:0019220 210 0.036
response to abiotic stimulus GO:0009628 341 0.035
single organism behavior GO:0044708 391 0.035
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.034
response to oxygen containing compound GO:1901700 200 0.034
phagocytosis GO:0006909 215 0.034
cellular catabolic process GO:0044248 372 0.034
immune response GO:0006955 246 0.033
establishment of localization in cell GO:0051649 402 0.033
regulation of catalytic activity GO:0050790 185 0.033
organonitrogen compound metabolic process GO:1901564 318 0.033
positive regulation of protein metabolic process GO:0051247 128 0.033
regulation of phosphorylation GO:0042325 147 0.032
organic substance catabolic process GO:1901575 308 0.032
stem cell differentiation GO:0048863 117 0.032
organophosphate metabolic process GO:0019637 195 0.032
compound eye development GO:0048749 307 0.031
regulation of response to stress GO:0080134 200 0.031
endocytosis GO:0006897 310 0.031
cellular protein modification process GO:0006464 438 0.031
regulation of catabolic process GO:0009894 170 0.030
cell division GO:0051301 248 0.030
regulation of cell death GO:0010941 173 0.030
aromatic compound catabolic process GO:0019439 166 0.030
regulation of anatomical structure morphogenesis GO:0022603 242 0.030
cell motility GO:0048870 251 0.030
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.030
neural precursor cell proliferation GO:0061351 75 0.030
regulation of gene expression epigenetic GO:0040029 128 0.029
positive regulation of developmental process GO:0051094 143 0.029
homeostatic process GO:0042592 199 0.029
negative regulation of transcription dna templated GO:0045892 237 0.029
actin cytoskeleton organization GO:0030036 206 0.029
positive regulation of cell communication GO:0010647 250 0.028
regulation of cellular catabolic process GO:0031329 157 0.028
eye morphogenesis GO:0048592 260 0.028
cellular macromolecule localization GO:0070727 220 0.027
appendage development GO:0048736 401 0.027
protein phosphorylation GO:0006468 169 0.027
negative regulation of cellular metabolic process GO:0031324 382 0.026
single organism intracellular transport GO:1902582 207 0.026
negative regulation of biosynthetic process GO:0009890 277 0.026
cellular macromolecular complex assembly GO:0034622 153 0.026
embryonic pattern specification GO:0009880 174 0.026
positive regulation of response to stimulus GO:0048584 323 0.026
response to biotic stimulus GO:0009607 294 0.025
post embryonic appendage morphogenesis GO:0035120 385 0.025
regulation of molecular function GO:0065009 217 0.025
asymmetric protein localization GO:0008105 33 0.025
nucleobase containing compound catabolic process GO:0034655 165 0.025
regulation of intracellular signal transduction GO:1902531 236 0.025
developmental maturation GO:0021700 172 0.025
positive regulation of macromolecule metabolic process GO:0010604 405 0.024
positive regulation of cellular component organization GO:0051130 156 0.024
immune system process GO:0002376 347 0.024
synaptic growth at neuromuscular junction GO:0051124 119 0.024
catabolic process GO:0009056 409 0.024
epithelial cell migration GO:0010631 148 0.024
chromatin organization GO:0006325 207 0.023
glycosyl compound catabolic process GO:1901658 112 0.023
regulation of programmed cell death GO:0043067 152 0.023
protein localization GO:0008104 284 0.023
regulation of nervous system development GO:0051960 248 0.023
stem cell proliferation GO:0072089 88 0.023
response to endogenous stimulus GO:0009719 119 0.023
organelle fission GO:0048285 340 0.022
establishment or maintenance of cell polarity GO:0007163 167 0.022
cellular response to chemical stimulus GO:0070887 199 0.022
positive regulation of cellular protein metabolic process GO:0032270 118 0.022
feeding behavior GO:0007631 50 0.022
nucleotide metabolic process GO:0009117 161 0.022
regulation of cell differentiation GO:0045595 302 0.022
muscle cell development GO:0055001 50 0.022
cytoplasmic transport GO:0016482 130 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.022
cell death GO:0008219 279 0.021
appendage morphogenesis GO:0035107 397 0.021
positive regulation of multicellular organismal process GO:0051240 143 0.021
organelle localization GO:0051640 148 0.021
cellular carbohydrate catabolic process GO:0044275 2 0.021
positive regulation of cell motility GO:2000147 3 0.021
muscle cell differentiation GO:0042692 103 0.021
positive regulation of programmed cell death GO:0043068 62 0.021
gene silencing GO:0016458 138 0.020
central nervous system development GO:0007417 201 0.020
negative regulation of nucleic acid templated transcription GO:1903507 240 0.020
nucleobase containing small molecule metabolic process GO:0055086 174 0.020
regulation of cell morphogenesis GO:0022604 163 0.020
striated muscle cell differentiation GO:0051146 90 0.020
rho protein signal transduction GO:0007266 14 0.020
cellular response to endogenous stimulus GO:0071495 80 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
cellular response to dna damage stimulus GO:0006974 223 0.020
negative regulation of developmental process GO:0051093 201 0.020
cell proliferation GO:0008283 299 0.019
eye photoreceptor cell differentiation GO:0001754 145 0.019
regionalization GO:0003002 416 0.019
leg disc development GO:0035218 92 0.019
compound eye morphogenesis GO:0001745 249 0.019
activation of innate immune response GO:0002218 4 0.019
positive regulation of immune system process GO:0002684 68 0.019
regulation of cell cycle GO:0051726 291 0.019
regulation of immune response GO:0050776 118 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
muscle structure development GO:0061061 224 0.019
positive regulation of cell migration GO:0030335 2 0.019
single organism catabolic process GO:0044712 228 0.019
programmed cell death GO:0012501 257 0.019
generation of precursor metabolites and energy GO:0006091 42 0.019
protein complex assembly GO:0006461 200 0.019
mesenchymal cell differentiation GO:0048762 1 0.019
regulation of purine nucleotide catabolic process GO:0033121 48 0.019
forebrain development GO:0030900 2 0.019
organic substance transport GO:0071702 257 0.019
sensory perception GO:0007600 196 0.019
positive regulation of catabolic process GO:0009896 105 0.018
regulation of multi organism process GO:0043900 131 0.018
regulation of immune system process GO:0002682 176 0.018
regulation of protein modification process GO:0031399 112 0.018
wing disc morphogenesis GO:0007472 344 0.018
morphogenesis of an epithelium GO:0002009 276 0.018
response to lipopolysaccharide GO:0032496 4 0.018
chromosome organization GO:0051276 360 0.018
actin filament organization GO:0007015 126 0.018
positive regulation of cellular biosynthetic process GO:0031328 316 0.018
immune response regulating signaling pathway GO:0002764 2 0.018
enzyme linked receptor protein signaling pathway GO:0007167 179 0.017
membrane organization GO:0061024 112 0.017
r7 cell differentiation GO:0045466 43 0.017
cytokinesis GO:0000910 90 0.017
proteolysis GO:0006508 192 0.017
axis specification GO:0009798 167 0.017
formation of primary germ layer GO:0001704 24 0.017
compound eye photoreceptor development GO:0042051 78 0.017
positive regulation of signaling GO:0023056 243 0.017
hindbrain development GO:0030902 2 0.017
regulation of nucleotide metabolic process GO:0006140 62 0.017
ribonucleotide catabolic process GO:0009261 109 0.017
response to external biotic stimulus GO:0043207 293 0.017
negative regulation of response to stimulus GO:0048585 258 0.016
cytoskeleton dependent cytokinesis GO:0061640 81 0.016
regulation of cellular component size GO:0032535 98 0.016
ameboidal type cell migration GO:0001667 151 0.016
cell cell signaling involved in cell fate commitment GO:0045168 210 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
innate immune response GO:0045087 144 0.016
guanosine containing compound metabolic process GO:1901068 74 0.016
mapk cascade GO:0000165 107 0.016
rna processing GO:0006396 147 0.016
negative regulation of signaling GO:0023057 219 0.016
protein modification by small protein conjugation GO:0032446 79 0.016
segmentation GO:0035282 207 0.016
establishment of synaptic vesicle localization GO:0097480 50 0.016
multi organism behavior GO:0051705 175 0.016
cellular protein localization GO:0034613 160 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
meiotic cell cycle GO:0051321 171 0.016
embryonic axis specification GO:0000578 107 0.016
macromolecule catabolic process GO:0009057 161 0.016
epithelium migration GO:0090132 148 0.015
regulation of cell development GO:0060284 215 0.015
extracellular structure organization GO:0043062 46 0.015
localization of cell GO:0051674 257 0.015
heterocycle catabolic process GO:0046700 166 0.015
ovarian follicle cell development GO:0030707 248 0.015
tissue migration GO:0090130 155 0.015
mesenchymal cell development GO:0014031 1 0.015
dorsal ventral pattern formation GO:0009953 133 0.015
oocyte construction GO:0007308 112 0.015
regulation of hydrolase activity GO:0051336 97 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
maternal determination of anterior posterior axis embryo GO:0008358 74 0.015
organic acid metabolic process GO:0006082 103 0.015
epithelial cell differentiation GO:0030855 322 0.015
cell migration GO:0016477 238 0.015
positive regulation of molecular function GO:0044093 136 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
neuron projection extension GO:1990138 32 0.014
regulation of localization GO:0032879 275 0.014
muscle organ development GO:0007517 127 0.014
pigmentation GO:0043473 75 0.014
oocyte axis specification GO:0007309 108 0.014
defense response to gram negative bacterium GO:0050829 94 0.014
single organism membrane organization GO:0044802 93 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.014
meiotic nuclear division GO:0007126 151 0.014
negative regulation of cell proliferation GO:0008285 69 0.014
negative regulation of nervous system development GO:0051961 92 0.014
posttranscriptional gene silencing GO:0016441 46 0.014
positive regulation of biosynthetic process GO:0009891 316 0.014
multicellular organism growth GO:0035264 46 0.014
cellular response to growth factor stimulus GO:0071363 30 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
compound eye photoreceptor cell differentiation GO:0001751 140 0.014
cellular response to oxygen containing compound GO:1901701 79 0.014
regulation of transferase activity GO:0051338 58 0.014
synapse assembly GO:0007416 143 0.014
imaginal disc pattern formation GO:0007447 91 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.013
oxoacid metabolic process GO:0043436 103 0.013
axon extension GO:0048675 32 0.013
body morphogenesis GO:0010171 2 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
microtubule based transport GO:0010970 42 0.013
sensory organ morphogenesis GO:0090596 260 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
gene silencing by rna GO:0031047 57 0.013
circulatory system development GO:0072359 82 0.013
regulation of cellular response to stress GO:0080135 89 0.013
regulation of synapse assembly GO:0051963 94 0.013
regulation of multicellular organismal development GO:2000026 414 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
stem cell division GO:0017145 69 0.013
response to organic cyclic compound GO:0014070 89 0.013
chemotaxis GO:0006935 249 0.012
spindle assembly GO:0051225 80 0.012
peptidyl threonine phosphorylation GO:0018107 2 0.012
cell fate determination GO:0001709 91 0.012
protein complex biogenesis GO:0070271 201 0.012
head development GO:0060322 135 0.012
mesoderm development GO:0007498 78 0.012
endomembrane system organization GO:0010256 119 0.012
synaptic vesicle localization GO:0097479 53 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
regulation of jnk cascade GO:0046328 40 0.012
developmental pigmentation GO:0048066 68 0.012
imaginal disc derived appendage development GO:0048737 399 0.012
actin cytoskeleton reorganization GO:0031532 22 0.012
nuclear transport GO:0051169 72 0.012
positive regulation of apoptotic process GO:0043065 47 0.012
nucleotide catabolic process GO:0009166 109 0.012
chromatin modification GO:0016568 147 0.012
negative regulation of molecular function GO:0044092 51 0.012
peptide metabolic process GO:0006518 80 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
gland morphogenesis GO:0022612 145 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
notch signaling pathway GO:0007219 120 0.012
positive regulation of gene expression GO:0010628 290 0.012
chorion containing eggshell pattern formation GO:0030381 11 0.012
locomotory behavior GO:0007626 176 0.012
response to growth factor GO:0070848 31 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
ribonucleoprotein complex biogenesis GO:0022613 31 0.011
cellular response to hormone stimulus GO:0032870 44 0.011
anterior posterior pattern specification GO:0009952 136 0.011
response to ethanol GO:0045471 59 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
cellular response to mechanical stimulus GO:0071260 2 0.011
regulation of proteolysis GO:0030162 87 0.011
wing disc pattern formation GO:0035222 66 0.011
regulation of gtpase activity GO:0043087 44 0.011
mitotic spindle organization GO:0007052 220 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
digestive tract morphogenesis GO:0048546 127 0.011
regulation of kinase activity GO:0043549 53 0.011
oocyte differentiation GO:0009994 145 0.011
taxis GO:0042330 304 0.011
response to nitrogen compound GO:1901698 90 0.011
asymmetric neuroblast division GO:0055059 33 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
regulation of response to external stimulus GO:0032101 115 0.011
spermatogenesis GO:0007283 200 0.011
purine nucleotide catabolic process GO:0006195 109 0.011
establishment of organelle localization GO:0051656 122 0.011
establishment of cell polarity GO:0030010 40 0.011
cellular homeostasis GO:0019725 80 0.011
regulation of cell shape GO:0008360 113 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
response to alcohol GO:0097305 95 0.011
oocyte anterior posterior axis specification GO:0007314 72 0.010
nucleus organization GO:0006997 45 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
imaginal disc derived appendage morphogenesis GO:0035114 395 0.010
regulation of nucleotide catabolic process GO:0030811 48 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
anterior posterior axis specification embryo GO:0008595 103 0.010
regulation of cellular component biogenesis GO:0044087 201 0.010
immune response activating signal transduction GO:0002757 2 0.010
transcription from rna polymerase ii promoter GO:0006366 368 0.010
spindle organization GO:0007051 253 0.010
regulation of nuclear division GO:0051783 58 0.010
synaptic transmission GO:0007268 288 0.010
extracellular matrix disassembly GO:0022617 4 0.010

Sur-8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
nervous system disease DOID:863 0 0.012
organ system cancer DOID:0050686 0 0.010