Drosophila melanogaster

100 known processes

lin-28 (Dmel_CG17334)

CG17334 gene product from transcript CG17334-RA

(Aliases: BcDNA:RE05342,CG17334,EP(3)0915,Dmel\CG17334)

lin-28 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism behavior GO:0044708 391 0.285
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.184
cell proliferation GO:0008283 299 0.122
negative regulation of cellular biosynthetic process GO:0031327 277 0.112
negative regulation of cellular metabolic process GO:0031324 382 0.107
multi organism behavior GO:0051705 175 0.104
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.102
negative regulation of gene expression GO:0010629 387 0.099
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.098
negative regulation of rna biosynthetic process GO:1902679 240 0.094
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.093
negative regulation of rna metabolic process GO:0051253 251 0.079
sensory organ morphogenesis GO:0090596 260 0.079
regulation of multicellular organismal development GO:2000026 414 0.075
neurological system process GO:0050877 358 0.073
death GO:0016265 284 0.071
transcription from rna polymerase ii promoter GO:0006366 368 0.069
locomotory behavior GO:0007626 176 0.061
immune system process GO:0002376 347 0.060
positive regulation of biosynthetic process GO:0009891 316 0.056
mating GO:0007618 120 0.054
adult behavior GO:0030534 137 0.053
negative regulation of transcription dna templated GO:0045892 237 0.052
regulation of immune system process GO:0002682 176 0.052
dendrite morphogenesis GO:0048813 199 0.052
regionalization GO:0003002 416 0.050
exocrine system development GO:0035272 162 0.049
regulation of cell death GO:0010941 173 0.048
regulation of cell proliferation GO:0042127 163 0.048
programmed cell death GO:0012501 257 0.048
salivary gland morphogenesis GO:0007435 145 0.046
nuclear division GO:0000280 332 0.044
gland development GO:0048732 191 0.044
positive regulation of cellular biosynthetic process GO:0031328 316 0.043
positive regulation of nucleic acid templated transcription GO:1903508 266 0.042
negative regulation of nucleic acid templated transcription GO:1903507 240 0.041
eye morphogenesis GO:0048592 260 0.041
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.040
chromosome organization GO:0051276 360 0.039
salivary gland development GO:0007431 162 0.039
tube morphogenesis GO:0035239 191 0.039
gland morphogenesis GO:0022612 145 0.038
multi organism reproductive behavior GO:0044705 121 0.037
cell death GO:0008219 279 0.037
response to abiotic stimulus GO:0009628 341 0.036
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.036
compound eye morphogenesis GO:0001745 249 0.035
nucleobase containing small molecule metabolic process GO:0055086 174 0.034
positive regulation of transcription dna templated GO:0045893 266 0.034
eye photoreceptor cell differentiation GO:0001754 145 0.033
organelle fission GO:0048285 340 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.032
body morphogenesis GO:0010171 2 0.032
photoreceptor cell differentiation GO:0046530 170 0.031
regulation of cell differentiation GO:0045595 302 0.031
urogenital system development GO:0001655 72 0.031
establishment of localization in cell GO:0051649 402 0.031
negative regulation of biosynthetic process GO:0009890 277 0.031
kidney development GO:0001822 3 0.031
imaginal disc derived appendage development GO:0048737 399 0.031
response to organic substance GO:0010033 284 0.030
positive regulation of gene expression GO:0010628 290 0.030
anatomical structure homeostasis GO:0060249 97 0.030
response to oxygen containing compound GO:1901700 200 0.030
regulation of anatomical structure morphogenesis GO:0022603 242 0.030
eye development GO:0001654 323 0.029
positive regulation of rna metabolic process GO:0051254 271 0.029
compound eye development GO:0048749 307 0.029
forebrain development GO:0030900 2 0.029
regulation of protein metabolic process GO:0051246 256 0.029
g protein coupled receptor signaling pathway GO:0007186 136 0.029
synaptic transmission GO:0007268 288 0.029
homeostatic process GO:0042592 199 0.028
stem cell proliferation GO:0072089 88 0.028
regulation of cell growth GO:0001558 43 0.028
positive regulation of multicellular organismal process GO:0051240 143 0.027
tissue morphogenesis GO:0048729 297 0.026
positive regulation of signaling GO:0023056 243 0.026
stem cell division GO:0017145 69 0.026
digestive tract development GO:0048565 149 0.026
chemotaxis GO:0006935 249 0.025
embryonic morphogenesis GO:0048598 206 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.025
imaginal disc pattern formation GO:0007447 91 0.025
developmental growth GO:0048589 280 0.025
adult locomotory behavior GO:0008344 76 0.024
reproductive behavior GO:0019098 122 0.024
regulation of cell projection organization GO:0031344 92 0.024
cell growth GO:0016049 108 0.024
intracellular signal transduction GO:0035556 300 0.024
multi multicellular organism process GO:0044706 123 0.023
digestive system development GO:0055123 149 0.023
regulation of response to stress GO:0080134 200 0.023
organic substance catabolic process GO:1901575 308 0.023
dendrite development GO:0016358 204 0.023
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
actin cytoskeleton organization GO:0030036 206 0.023
ameboidal type cell migration GO:0001667 151 0.023
regulation of cellular amine metabolic process GO:0033238 3 0.023
mitotic nuclear division GO:0007067 213 0.023
tube development GO:0035295 244 0.023
organonitrogen compound metabolic process GO:1901564 318 0.022
small molecule metabolic process GO:0044281 305 0.022
response to biotic stimulus GO:0009607 294 0.022
cellular catabolic process GO:0044248 372 0.022
positive regulation of immune system process GO:0002684 68 0.022
protein localization GO:0008104 284 0.022
macromolecule catabolic process GO:0009057 161 0.022
regulation of programmed cell death GO:0043067 152 0.022
asymmetric stem cell division GO:0098722 49 0.022
mesoderm development GO:0007498 78 0.022
regulation of apoptotic process GO:0042981 130 0.022
single organism biosynthetic process GO:0044711 206 0.022
chromatin modification GO:0016568 147 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.022
central nervous system development GO:0007417 201 0.021
camera type eye development GO:0043010 4 0.021
response to sterol GO:0036314 34 0.021
protein modification process GO:0036211 438 0.021
regulation of localization GO:0032879 275 0.021
localization of cell GO:0051674 257 0.021
organic substance transport GO:0071702 257 0.021
morphogenesis of an epithelium GO:0002009 276 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.021
single organism catabolic process GO:0044712 228 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.021
positive regulation of protein metabolic process GO:0051247 128 0.020
negative regulation of cell communication GO:0010648 223 0.020
segmentation GO:0035282 207 0.020
regulation of nervous system development GO:0051960 248 0.020
positive regulation of cell proliferation GO:0008284 47 0.020
catabolic process GO:0009056 409 0.020
positive regulation of cellular component organization GO:0051130 156 0.020
neural precursor cell proliferation GO:0061351 75 0.020
regulation of cell morphogenesis GO:0022604 163 0.020
cell division GO:0051301 248 0.020
developmental programmed cell death GO:0010623 138 0.020
chromatin organization GO:0006325 207 0.020
nucleotide metabolic process GO:0009117 161 0.019
negative regulation of cellular component organization GO:0051129 108 0.019
proteolysis GO:0006508 192 0.019
phosphorylation GO:0016310 294 0.019
meiotic nuclear division GO:0007126 151 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.019
salivary gland histolysis GO:0035070 88 0.019
negative regulation of developmental process GO:0051093 201 0.019
purine containing compound metabolic process GO:0072521 155 0.019
renal tubule development GO:0061326 64 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
response to lipopolysaccharide GO:0032496 4 0.019
positive regulation of cell communication GO:0010647 250 0.019
regulation of cell development GO:0060284 215 0.018
muscle organ development GO:0007517 127 0.018
response to other organism GO:0051707 293 0.018
ras protein signal transduction GO:0007265 88 0.018
response to alcohol GO:0097305 95 0.018
covalent chromatin modification GO:0016569 106 0.018
regulation of cellular component biogenesis GO:0044087 201 0.018
histone modification GO:0016570 106 0.018
cellular protein modification process GO:0006464 438 0.018
vesicle mediated transport GO:0016192 381 0.018
meiotic cell cycle GO:0051321 171 0.018
apoptotic process GO:0006915 159 0.018
mesenchymal cell development GO:0014031 1 0.018
macromolecular complex assembly GO:0065003 256 0.017
regulation of cell cycle GO:0051726 291 0.017
positive regulation of molecular function GO:0044093 136 0.017
purine nucleoside triphosphate metabolic process GO:0009144 119 0.017
appendage development GO:0048736 401 0.017
blastoderm segmentation GO:0007350 159 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
chromatin silencing GO:0006342 76 0.017
regulation of immune response GO:0050776 118 0.017
regulation of developmental growth GO:0048638 174 0.017
renal tubule morphogenesis GO:0061333 44 0.017
regulation of cellular localization GO:0060341 136 0.017
head development GO:0060322 135 0.017
embryonic pattern specification GO:0009880 174 0.017
mating behavior GO:0007617 106 0.017
secretion GO:0046903 109 0.017
malpighian tubule development GO:0072002 64 0.017
regulation of mitotic cell cycle GO:0007346 190 0.017
positive regulation of response to stimulus GO:0048584 323 0.017
negative regulation of nervous system development GO:0051961 92 0.016
dorsal ventral pattern formation GO:0009953 133 0.016
multicellular organismal reproductive behavior GO:0033057 110 0.016
regulation of anatomical structure size GO:0090066 163 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
regulation of transport GO:0051049 181 0.016
mesenchymal cell differentiation GO:0048762 1 0.016
immune response activating signal transduction GO:0002757 2 0.016
hindgut morphogenesis GO:0007442 58 0.016
digestive tract morphogenesis GO:0048546 127 0.016
endocytosis GO:0006897 310 0.016
appendage morphogenesis GO:0035107 397 0.016
negative regulation of cell death GO:0060548 81 0.016
negative regulation of multicellular organismal process GO:0051241 142 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
immune response GO:0006955 246 0.016
immune effector process GO:0002252 98 0.016
detection of stimulus GO:0051606 156 0.016
intracellular transport GO:0046907 228 0.016
telencephalon development GO:0021537 2 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
carbohydrate derivative biosynthetic process GO:1901137 85 0.016
purine ribonucleotide metabolic process GO:0009150 145 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
photoreceptor cell development GO:0042461 96 0.016
chromosome segregation GO:0007059 157 0.015
oxoacid metabolic process GO:0043436 103 0.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.015
positive regulation of cell motility GO:2000147 3 0.015
positive regulation of cell migration GO:0030335 2 0.015
learning or memory GO:0007611 141 0.015
protein maturation GO:0051604 71 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
ribonucleotide metabolic process GO:0009259 145 0.015
regulation of gene silencing GO:0060968 63 0.015
heterocycle catabolic process GO:0046700 166 0.015
regulation of epithelial cell differentiation GO:0030856 4 0.015
renal system development GO:0072001 72 0.015
regulation of cellular response to stress GO:0080135 89 0.015
carboxylic acid metabolic process GO:0019752 92 0.015
neuroblast proliferation GO:0007405 74 0.015
regulation of multi organism process GO:0043900 131 0.015
histolysis GO:0007559 102 0.015
amine metabolic process GO:0009308 12 0.015
positive regulation of rna biosynthetic process GO:1902680 266 0.015
regulation of catabolic process GO:0009894 170 0.015
mrna metabolic process GO:0016071 124 0.015
protein complex assembly GO:0006461 200 0.014
hindgut development GO:0061525 58 0.014
stem cell differentiation GO:0048863 117 0.014
positive regulation of growth GO:0045927 75 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
negative regulation of cell cycle process GO:0010948 109 0.014
autophagy GO:0006914 108 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
positive regulation of signal transduction GO:0009967 223 0.014
nucleoside triphosphate metabolic process GO:0009141 120 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
actin filament based process GO:0030029 220 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
synapse assembly GO:0007416 143 0.014
eye photoreceptor cell development GO:0042462 81 0.014
regulation of gene expression epigenetic GO:0040029 128 0.014
epithelial cell development GO:0002064 274 0.014
positive regulation of developmental process GO:0051094 143 0.014
cellular response to biotic stimulus GO:0071216 4 0.013
cognition GO:0050890 141 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
compound eye photoreceptor cell differentiation GO:0001751 140 0.013
negative regulation of cell proliferation GO:0008285 69 0.013
response to organic cyclic compound GO:0014070 89 0.013
regulation of catalytic activity GO:0050790 185 0.013
malpighian tubule morphogenesis GO:0007443 44 0.013
endomembrane system organization GO:0010256 119 0.013
tissue death GO:0016271 102 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
phagocytosis GO:0006909 215 0.013
transmembrane transport GO:0055085 139 0.013
developmental cell growth GO:0048588 52 0.013
eye antennal disc development GO:0035214 60 0.013
inter male aggressive behavior GO:0002121 60 0.013
secretion by cell GO:0032940 101 0.013
organelle localization GO:0051640 148 0.013
cell maturation GO:0048469 144 0.013
cellular macromolecule localization GO:0070727 220 0.013
protein complex biogenesis GO:0070271 201 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
regulation of response to external stimulus GO:0032101 115 0.013
instar larval development GO:0002168 55 0.013
neuromuscular junction development GO:0007528 149 0.013
brain development GO:0007420 120 0.013
regulation of proteolysis GO:0030162 87 0.013
retina development in camera type eye GO:0060041 4 0.013
developmental maturation GO:0021700 172 0.013
positive regulation of organelle organization GO:0010638 65 0.012
hindbrain development GO:0030902 2 0.012
negative regulation of cell cycle GO:0045786 116 0.012
taxis GO:0042330 304 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
growth GO:0040007 359 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.012
positive regulation of programmed cell death GO:0043068 62 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
carbohydrate metabolic process GO:0005975 82 0.012
organophosphate metabolic process GO:0019637 195 0.012
regulation of neurogenesis GO:0050767 158 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.012
organic acid metabolic process GO:0006082 103 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
larval behavior GO:0030537 42 0.012
mitotic cell cycle embryonic GO:0045448 38 0.012
negative regulation of developmental growth GO:0048640 64 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
oocyte differentiation GO:0009994 145 0.012
regulation of organ morphogenesis GO:2000027 78 0.012
negative regulation of response to stimulus GO:0048585 258 0.012
wing disc pattern formation GO:0035222 66 0.012
cellular response to organic substance GO:0071310 132 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
neuron fate commitment GO:0048663 50 0.012
regulation of molecular function GO:0065009 217 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
neuropeptide signaling pathway GO:0007218 45 0.012
positive regulation of transport GO:0051050 92 0.012
olfactory behavior GO:0042048 97 0.012
embryonic hindgut morphogenesis GO:0048619 48 0.012
glycoprotein metabolic process GO:0009100 41 0.012
muscle structure development GO:0061061 224 0.012
negative regulation of growth GO:0045926 84 0.011
connective tissue development GO:0061448 3 0.011
regulation of cell division GO:0051302 72 0.011
muscle cell differentiation GO:0042692 103 0.011
epithelial tube morphogenesis GO:0060562 88 0.011
mitotic cytokinesis GO:0000281 50 0.011
autophagic cell death GO:0048102 83 0.011
positive regulation of protein transport GO:0051222 37 0.011
pigment metabolic process GO:0042440 84 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
lateral inhibition GO:0046331 206 0.011
phenol containing compound metabolic process GO:0018958 57 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
regulation of embryonic development GO:0045995 68 0.011
regulation of immune effector process GO:0002697 52 0.011
aromatic compound catabolic process GO:0019439 166 0.011
stem cell development GO:0048864 79 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
regulation of mrna processing GO:0050684 71 0.011
cell fate determination GO:0001709 91 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
axon guidance GO:0007411 233 0.011
organelle assembly GO:0070925 198 0.011
response to ketone GO:1901654 34 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
chemosensory behavior GO:0007635 106 0.011
sister chromatid segregation GO:0000819 92 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.011
nephron morphogenesis GO:0072028 3 0.011
rna localization GO:0006403 115 0.011
leg disc development GO:0035218 92 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
cytoplasmic transport GO:0016482 130 0.011
negative regulation of signaling GO:0023057 219 0.011
regulation of chromosome organization GO:0033044 64 0.011
female mating behavior GO:0060180 30 0.010
cellular homeostasis GO:0019725 80 0.010
phototransduction GO:0007602 52 0.010
nitrogen compound transport GO:0071705 85 0.010
axon development GO:0061564 297 0.010
regulation of cell cycle process GO:0010564 181 0.010
circadian behavior GO:0048512 76 0.010
regulation of organelle organization GO:0033043 196 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
regulation of growth GO:0040008 233 0.010
protein secretion GO:0009306 45 0.010
regulation of mitosis GO:0007088 56 0.010
response to radiation GO:0009314 155 0.010
response to external biotic stimulus GO:0043207 293 0.010
protein transport GO:0015031 155 0.010
organ growth GO:0035265 56 0.010
response to nitrogen compound GO:1901698 90 0.010
regulation of cell shape GO:0008360 113 0.010
establishment of organelle localization GO:0051656 122 0.010
enzyme linked receptor protein signaling pathway GO:0007167 179 0.010
negative regulation of gene expression epigenetic GO:0045814 77 0.010
nephron development GO:0072006 3 0.010
gastrulation GO:0007369 70 0.010
positive regulation of cellular catabolic process GO:0031331 95 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010

lin-28 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.019
sensory system disease DOID:0050155 0 0.010