Drosophila melanogaster

18 known processes

TppII (Dmel_CG3991)

tripeptidyl-peptidase II

(Aliases: anon-WO0118547.127,l(2)k14301,TPP2,dTPPII,TPPII,Dmel\CG3991,TPP II,CG3991,dTPP II)

TppII biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 152 0.433
body morphogenesis GO:0010171 2 0.211
cellular macromolecule catabolic process GO:0044265 136 0.133
cellular catabolic process GO:0044248 372 0.128
defense response GO:0006952 300 0.127
cellular macromolecular complex assembly GO:0034622 153 0.127
macromolecular complex assembly GO:0065003 256 0.115
catabolic process GO:0009056 409 0.097
multicellular organismal aging GO:0010259 140 0.077
g2 dna damage checkpoint GO:0031572 69 0.076
nuclear pore organization GO:0006999 1 0.071
response to external biotic stimulus GO:0043207 293 0.071
larval development GO:0002164 104 0.070
positive regulation of macromolecule metabolic process GO:0010604 405 0.068
protein complex biogenesis GO:0070271 201 0.067
multicellular organismal reproductive behavior GO:0033057 110 0.067
regulation of cellular protein metabolic process GO:0032268 243 0.066
positive regulation of cellular biosynthetic process GO:0031328 316 0.062
snrna 3 end processing GO:0034472 14 0.061
response to other organism GO:0051707 293 0.056
cell proliferation GO:0008283 299 0.056
organic substance catabolic process GO:1901575 308 0.054
mitotic spindle organization GO:0007052 220 0.054
regulation of protein metabolic process GO:0051246 256 0.053
rna 3 end processing GO:0031123 45 0.051
nucleoside phosphate metabolic process GO:0006753 162 0.050
macromolecule catabolic process GO:0009057 161 0.050
rna processing GO:0006396 147 0.049
oxoacid metabolic process GO:0043436 103 0.047
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.046
cellular protein modification process GO:0006464 438 0.045
regulation of developmental growth GO:0048638 174 0.045
modification dependent protein catabolic process GO:0019941 78 0.044
transcription from rna polymerase ii promoter GO:0006366 368 0.044
protein catabolic process GO:0030163 101 0.043
protein complex assembly GO:0006461 200 0.042
modification dependent macromolecule catabolic process GO:0043632 79 0.041
exocrine system development GO:0035272 162 0.041
salivary gland development GO:0007431 162 0.041
positive regulation of cellular protein metabolic process GO:0032270 118 0.040
mrna metabolic process GO:0016071 124 0.040
salivary gland morphogenesis GO:0007435 145 0.040
multi organism behavior GO:0051705 175 0.039
proteolysis GO:0006508 192 0.039
regulation of cellular component biogenesis GO:0044087 201 0.038
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.038
dna metabolic process GO:0006259 227 0.037
spindle organization GO:0007051 253 0.036
snrna processing GO:0016180 14 0.036
negative regulation of cellular biosynthetic process GO:0031327 277 0.036
determination of adult lifespan GO:0008340 137 0.036
response to biotic stimulus GO:0009607 294 0.035
carboxylic acid metabolic process GO:0019752 92 0.035
ubiquitin dependent protein catabolic process GO:0006511 78 0.035
regulation of multicellular organismal development GO:2000026 414 0.035
mating GO:0007618 120 0.034
rna splicing GO:0008380 83 0.034
cellular protein localization GO:0034613 160 0.033
positive regulation of developmental process GO:0051094 143 0.032
regulation of cellular catabolic process GO:0031329 157 0.032
mrna processing GO:0006397 104 0.031
organic cyclic compound catabolic process GO:1901361 168 0.031
regulation of organelle organization GO:0033043 196 0.031
regulation of response to stress GO:0080134 200 0.031
cellular protein catabolic process GO:0044257 83 0.030
aging GO:0007568 143 0.030
dna templated transcription elongation GO:0006354 18 0.030
purine ribonucleoside catabolic process GO:0046130 112 0.030
cell division GO:0051301 248 0.030
gland development GO:0048732 191 0.029
innate immune response GO:0045087 144 0.028
organophosphate metabolic process GO:0019637 195 0.028
cellular component disassembly GO:0022411 46 0.028
regulation of cellular protein catabolic process GO:1903362 44 0.027
cellular protein complex assembly GO:0043623 71 0.027
developmental growth GO:0048589 280 0.027
purine ribonucleotide metabolic process GO:0009150 145 0.027
maintenance of location GO:0051235 73 0.027
Worm
posttranscriptional regulation of gene expression GO:0010608 145 0.026
establishment or maintenance of cell polarity GO:0007163 167 0.026
mitotic nuclear division GO:0007067 213 0.026
organic acid metabolic process GO:0006082 103 0.026
purine containing compound metabolic process GO:0072521 155 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
negative regulation of gene expression GO:0010629 387 0.025
nucleobase containing small molecule metabolic process GO:0055086 174 0.025
small molecule metabolic process GO:0044281 305 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.025
nucleoside metabolic process GO:0009116 127 0.025
cell motility GO:0048870 251 0.025
rna polyadenylation GO:0043631 12 0.024
positive regulation of biosynthetic process GO:0009891 316 0.024
ubiquitin homeostasis GO:0010992 1 0.024
single organism behavior GO:0044708 391 0.024
aromatic compound catabolic process GO:0019439 166 0.024
gland morphogenesis GO:0022612 145 0.024
neuron death GO:0070997 27 0.023
enzyme linked receptor protein signaling pathway GO:0007167 179 0.023
reproductive system development GO:0061458 74 0.022
mitotic g2 dna damage checkpoint GO:0007095 69 0.022
immune system process GO:0002376 347 0.022
positive regulation of cell migration GO:0030335 2 0.022
peptide metabolic process GO:0006518 80 0.022
immune effector process GO:0002252 98 0.021
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.021
ribonucleoside metabolic process GO:0009119 127 0.021
heterocycle catabolic process GO:0046700 166 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.021
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.021
death GO:0016265 284 0.020
meiotic cell cycle GO:0051321 171 0.020
cell death GO:0008219 279 0.020
proteasomal protein catabolic process GO:0010498 59 0.020
mrna polyadenylation GO:0006378 11 0.020
regulation of immune system process GO:0002682 176 0.020
positive regulation of protein metabolic process GO:0051247 128 0.019
immune response GO:0006955 246 0.019
positive regulation of proteolysis GO:0045862 52 0.019
ribose phosphate metabolic process GO:0019693 145 0.019
ribonucleotide metabolic process GO:0009259 145 0.018
er associated ubiquitin dependent protein catabolic process GO:0030433 3 0.018
regulation of cytoskeleton organization GO:0051493 89 0.018
organonitrogen compound catabolic process GO:1901565 128 0.018
regulation of response to external stimulus GO:0032101 115 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
regulation of mrna metabolic process GO:1903311 72 0.018
negative regulation of response to stimulus GO:0048585 258 0.018
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.017
multi multicellular organism process GO:0044706 123 0.017
regulation of proteolysis GO:0030162 87 0.017
nucleotide catabolic process GO:0009166 109 0.017
positive regulation of multicellular organismal process GO:0051240 143 0.017
endocytosis GO:0006897 310 0.017
regulation of protein complex assembly GO:0043254 42 0.017
protein targeting to nucleus GO:0044744 51 0.016
regulation of synapse structure and activity GO:0050803 128 0.016
rna interference GO:0016246 27 0.016
dna repair GO:0006281 54 0.016
nucleotide metabolic process GO:0009117 161 0.016
mitotic dna integrity checkpoint GO:0044774 75 0.016
neurological system process GO:0050877 358 0.016
purine ribonucleoside metabolic process GO:0046128 127 0.016
negative regulation of neuron death GO:1901215 18 0.015
homeostatic process GO:0042592 199 0.015
defense response to bacterium GO:0042742 178 0.015
negative regulation of cellular metabolic process GO:0031324 382 0.015
protein complex disassembly GO:0043241 36 0.015
rna catabolic process GO:0006401 37 0.015
regulation of cell development GO:0060284 215 0.015
regulation of catalytic activity GO:0050790 185 0.015
mitotic spindle elongation GO:0000022 81 0.015
positive regulation of cellular component organization GO:0051130 156 0.015
regulation of protein stability GO:0031647 43 0.015
response to bacterium GO:0009617 198 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
regulation of catabolic process GO:0009894 170 0.014
reproductive behavior GO:0019098 122 0.014
response to lipopolysaccharide GO:0032496 4 0.014
ncrna 3 end processing GO:0043628 17 0.014
positive regulation of cellular catabolic process GO:0031331 95 0.014
mesenchymal cell development GO:0014031 1 0.014
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.014
positive regulation of cellular component biogenesis GO:0044089 80 0.014
negative regulation of multicellular organismal process GO:0051241 142 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.013
regulation of nervous system development GO:0051960 248 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.013
protein localization GO:0008104 284 0.013
localization of cell GO:0051674 257 0.013
ncrna metabolic process GO:0034660 43 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
macromolecular complex disassembly GO:0032984 37 0.013
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.013
positive regulation of nervous system development GO:0051962 69 0.013
nuclear import GO:0051170 51 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
regulation of cellular amide metabolic process GO:0034248 39 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
phagocytosis GO:0006909 215 0.012
sex differentiation GO:0007548 81 0.012
cell migration GO:0016477 238 0.012
taxis GO:0042330 304 0.012
protein modification by small protein conjugation or removal GO:0070647 106 0.012
positive regulation of gene expression GO:0010628 290 0.012
programmed cell death GO:0012501 257 0.012
regulation of immune response GO:0050776 118 0.012
protein transport GO:0015031 155 0.012
amine metabolic process GO:0009308 12 0.012
single organism catabolic process GO:0044712 228 0.012
tissue death GO:0016271 102 0.012
cytoplasmic transport GO:0016482 130 0.012
regulation of mrna processing GO:0050684 71 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
regulation of cell cycle GO:0051726 291 0.012
mesenchymal cell differentiation GO:0048762 1 0.011
organelle assembly GO:0070925 198 0.011
establishment of protein localization GO:0045184 163 0.011
behavioral response to pain GO:0048266 3 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
single organism cellular localization GO:1902580 180 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
cellular homeostasis GO:0019725 80 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
organonitrogen compound metabolic process GO:1901564 318 0.011
snrna metabolic process GO:0016073 14 0.011
protein import GO:0017038 55 0.011
nucleoside monophosphate metabolic process GO:0009123 52 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
rna localization GO:0006403 115 0.011
cellular amide metabolic process GO:0043603 80 0.011
protein modification process GO:0036211 438 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
spindle elongation GO:0051231 83 0.011
regulation of defense response GO:0031347 102 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
protein deubiquitination GO:0016579 17 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
organic substance transport GO:0071702 257 0.011
positive regulation of catabolic process GO:0009896 105 0.011
regulation of synapse assembly GO:0051963 94 0.010
microtubule organizing center organization GO:0031023 168 0.010
regulation of dna templated transcription elongation GO:0032784 17 0.010
single organism nuclear import GO:1902593 51 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.010
mitotic g2 m transition checkpoint GO:0044818 70 0.010
negative regulation of mitotic cell cycle GO:0045930 109 0.010
mrna catabolic process GO:0006402 33 0.010
response to alcohol GO:0097305 95 0.010

TppII disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
nervous system disease DOID:863 0 0.017