Drosophila melanogaster

79 known processes

TBPH (Dmel_CG10327)

CG10327 gene product from transcript CG10327-RC

(Aliases: Dmel\CG10327,TDP-43,dtar,CG10327)

TBPH biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuromuscular junction development GO:0007528 149 0.999
axon development GO:0061564 297 0.998
Zebrafish
synapse organization GO:0050808 196 0.998
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.997
regulation of synapse organization GO:0050807 110 0.978
synapse assembly GO:0007416 143 0.977
response to alcohol GO:0097305 95 0.971
neuromuscular synaptic transmission GO:0007274 67 0.969
regulation of neurogenesis GO:0050767 158 0.946
sensory organ morphogenesis GO:0090596 260 0.934
regulation of nervous system development GO:0051960 248 0.920
regulation of multicellular organismal development GO:2000026 414 0.919
negative regulation of nervous system development GO:0051961 92 0.911
eye morphogenesis GO:0048592 260 0.908
compound eye morphogenesis GO:0001745 249 0.897
positive regulation of developmental process GO:0051094 143 0.879
single organism behavior GO:0044708 391 0.878
positive regulation of multicellular organismal process GO:0051240 143 0.870
central nervous system development GO:0007417 201 0.860
regulation of cell differentiation GO:0045595 302 0.858
positive regulation of response to stimulus GO:0048584 323 0.857
regulation of neuron differentiation GO:0045664 103 0.856
tube development GO:0035295 244 0.847
growth GO:0040007 359 0.847
intracellular transport GO:0046907 228 0.837
regulation of synapse assembly GO:0051963 94 0.829
cellular macromolecular complex assembly GO:0034622 153 0.810
larval locomotory behavior GO:0008345 27 0.808
neuron projection guidance GO:0097485 241 0.801
dendrite development GO:0016358 204 0.790
positive regulation of nervous system development GO:0051962 69 0.788
transcription from rna polymerase ii promoter GO:0006366 368 0.785
Mouse
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.779
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.774
Mouse
adult locomotory behavior GO:0008344 76 0.763
synaptic vesicle transport GO:0048489 50 0.755
negative regulation of cell development GO:0010721 62 0.744
positive regulation of cell differentiation GO:0045597 64 0.732
regulation of vesicle mediated transport GO:0060627 59 0.688
synaptic transmission GO:0007268 288 0.650
adult behavior GO:0030534 137 0.647
locomotory behavior GO:0007626 176 0.637
muscle structure development GO:0061061 224 0.611
regulation of cell projection organization GO:0031344 92 0.602
establishment of localization in cell GO:0051649 402 0.596
establishment of organelle localization GO:0051656 122 0.596
regulation of cell development GO:0060284 215 0.595
tissue morphogenesis GO:0048729 297 0.580
axonogenesis GO:0007409 290 0.580
Zebrafish
cellular protein complex assembly GO:0043623 71 0.577
synaptic vesicle recycling GO:0036465 28 0.574
positive regulation of cellular component organization GO:0051130 156 0.561
response to oxygen containing compound GO:1901700 200 0.547
regulation of response to external stimulus GO:0032101 115 0.547
immune system process GO:0002376 347 0.546
establishment of synaptic vesicle localization GO:0097480 50 0.532
gliogenesis GO:0042063 80 0.523
compound eye photoreceptor development GO:0042051 78 0.508
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.502
establishment or maintenance of cell polarity GO:0007163 167 0.495
eye development GO:0001654 323 0.491
embryonic morphogenesis GO:0048598 206 0.490
synaptic growth at neuromuscular junction GO:0051124 119 0.464
regulation of synapse structure and activity GO:0050803 128 0.446
compound eye development GO:0048749 307 0.445
synaptic vesicle endocytosis GO:0048488 28 0.436
positive regulation of synapse assembly GO:0051965 29 0.430
regulation of anatomical structure morphogenesis GO:0022603 242 0.430
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.430
Mouse
positive regulation of developmental growth GO:0048639 62 0.421
regulation of cell death GO:0010941 173 0.421
establishment of vesicle localization GO:0051650 51 0.418
autophagy GO:0006914 108 0.417
regulation of cell morphogenesis GO:0022604 163 0.409
small molecule metabolic process GO:0044281 305 0.404
regulation of membrane potential GO:0042391 35 0.398
morphogenesis of an epithelium GO:0002009 276 0.388
forebrain development GO:0030900 2 0.382
cell division GO:0051301 248 0.382
regulation of protein metabolic process GO:0051246 256 0.382
negative regulation of cell differentiation GO:0045596 143 0.380
axon guidance GO:0007411 233 0.374
response to hydrogen peroxide GO:0042542 11 0.362
synaptic vesicle localization GO:0097479 53 0.357
negative regulation of gene expression GO:0010629 387 0.356
Human
cellular response to chemical stimulus GO:0070887 199 0.355
neurotransmitter secretion GO:0007269 35 0.340
mrna metabolic process GO:0016071 124 0.338
organelle localization GO:0051640 148 0.336
positive regulation of cell communication GO:0010647 250 0.336
regulation of organelle organization GO:0033043 196 0.333
regulation of cellular protein metabolic process GO:0032268 243 0.317
cellular protein modification process GO:0006464 438 0.310
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.301
brain development GO:0007420 120 0.299
positive regulation of macromolecule metabolic process GO:0010604 405 0.294
Mouse
regulation of phosphorylation GO:0042325 147 0.290
regulation of anatomical structure size GO:0090066 163 0.288
imaginal disc derived appendage morphogenesis GO:0035114 395 0.283
vesicle localization GO:0051648 55 0.279
epithelial cell migration GO:0010631 148 0.275
neuron projection extension GO:1990138 32 0.274
Zebrafish
response to ketone GO:1901654 34 0.260
macromolecular complex assembly GO:0065003 256 0.254
response to abiotic stimulus GO:0009628 341 0.253
glial cell differentiation GO:0010001 35 0.245
negative regulation of neurogenesis GO:0050768 53 0.244
head development GO:0060322 135 0.239
neurological system process GO:0050877 358 0.238
cellular response to nutrient levels GO:0031669 62 0.236
negative regulation of developmental process GO:0051093 201 0.234
regulation of endocytosis GO:0030100 37 0.226
negative regulation of rna biosynthetic process GO:1902679 240 0.221
Human
cellular response to external stimulus GO:0071496 66 0.219
negative regulation of response to stimulus GO:0048585 258 0.219
protein modification process GO:0036211 438 0.219
eye photoreceptor cell differentiation GO:0001754 145 0.217
positive regulation of signaling GO:0023056 243 0.204
organelle fission GO:0048285 340 0.202
compound eye photoreceptor cell differentiation GO:0001751 140 0.193
proteolysis GO:0006508 192 0.192
regulation of immune system process GO:0002682 176 0.190
axon cargo transport GO:0008088 29 0.190
response to organic substance GO:0010033 284 0.190
epithelial cell differentiation GO:0030855 322 0.183
chromosome organization GO:0051276 360 0.182
regulation of autophagy GO:0010506 62 0.179
dendrite morphogenesis GO:0048813 199 0.179
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.179
Mouse
protein complex biogenesis GO:0070271 201 0.179
negative regulation of multicellular organismal process GO:0051241 142 0.178
eye photoreceptor cell development GO:0042462 81 0.172
positive regulation of cellular protein metabolic process GO:0032270 118 0.172
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.171
Human
cell adhesion GO:0007155 136 0.170
meiotic nuclear division GO:0007126 151 0.168
programmed cell death GO:0012501 257 0.166
positive regulation of cellular amine metabolic process GO:0033240 0 0.164
cell proliferation GO:0008283 299 0.164
response to endogenous stimulus GO:0009719 119 0.163
protein phosphorylation GO:0006468 169 0.156
positive regulation of axonogenesis GO:0050772 2 0.155
positive regulation of axon extension GO:0045773 2 0.155
tube morphogenesis GO:0035239 191 0.154
single organism cellular localization GO:1902580 180 0.150
positive regulation of neurogenesis GO:0050769 41 0.142
chemotaxis GO:0006935 249 0.139
death GO:0016265 284 0.137
enzyme linked receptor protein signaling pathway GO:0007167 179 0.134
cellular response to starvation GO:0009267 61 0.128
positive regulation of signal transduction GO:0009967 223 0.128
synaptic transmission dopaminergic GO:0001963 2 0.128
regulation of neuron projection development GO:0010975 69 0.127
response to extracellular stimulus GO:0009991 116 0.126
g protein coupled receptor signaling pathway GO:0007186 136 0.125
imaginal disc derived appendage development GO:0048737 399 0.121
positive regulation of cell death GO:0010942 69 0.121
negative regulation of signaling GO:0023057 219 0.120
segmentation GO:0035282 207 0.117
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.115
taxis GO:0042330 304 0.114
single organism cell adhesion GO:0098602 47 0.114
regulation of dendrite development GO:0050773 37 0.114
regulation of synaptic transmission GO:0050804 69 0.113
positive regulation of cell development GO:0010720 61 0.112
positive regulation of protein modification process GO:0031401 58 0.110
positive regulation of axon guidance GO:1902669 1 0.110
cellular response to extracellular stimulus GO:0031668 64 0.107
regulation of protein kinase activity GO:0045859 51 0.102
regulation of synaptic plasticity GO:0048167 14 0.102
cell death GO:0008219 279 0.101
protein complex assembly GO:0006461 200 0.098
terminal button organization GO:0072553 19 0.094
response to bacterium GO:0009617 198 0.093
neural precursor cell proliferation GO:0061351 75 0.091
regulation of neuroblast proliferation GO:1902692 34 0.090
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.089
Mouse
axon extension involved in axon guidance GO:0048846 10 0.087
regulation of membrane depolarization GO:0003254 1 0.085
regulation of stem cell proliferation GO:0072091 40 0.084
vesicle mediated transport GO:0016192 381 0.083
ameboidal type cell migration GO:0001667 151 0.083
ovarian follicle cell development GO:0030707 248 0.083
stem cell differentiation GO:0048863 117 0.083
regulation of response to oxidative stress GO:1902882 4 0.082
negative regulation of synapse assembly GO:0051964 39 0.081
negative regulation of cellular component organization GO:0051129 108 0.081
axon extension GO:0048675 32 0.081
Zebrafish
positive regulation of transport GO:0051050 92 0.080
regulation of cellular component size GO:0032535 98 0.079
carbohydrate derivative catabolic process GO:1901136 118 0.077
macroautophagy GO:0016236 42 0.076
regulation of phosphorus metabolic process GO:0051174 210 0.076
mushroom body development GO:0016319 70 0.074
mitochondrial fission GO:0000266 8 0.072
regulation of response to stress GO:0080134 200 0.071
response to ecdysone GO:0035075 34 0.071
establishment of mitochondrion localization GO:0051654 7 0.071
regionalization GO:0003002 416 0.071
anterior posterior pattern specification GO:0009952 136 0.071
regulation of protein phosphorylation GO:0001932 64 0.071
membrane depolarization GO:0051899 4 0.070
negative regulation of cell proliferation GO:0008285 69 0.070
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.069
regulation of cellular response to stress GO:0080135 89 0.068
positive regulation of apoptotic signaling pathway GO:2001235 4 0.066
regulation of behavior GO:0050795 75 0.065
developmental growth GO:0048589 280 0.065
neuron neuron synaptic transmission GO:0007270 14 0.065
positive regulation of molecular function GO:0044093 136 0.064
regulation of dendrite morphogenesis GO:0048814 28 0.063
regulation of short term neuronal synaptic plasticity GO:0048172 5 0.062
heart process GO:0003015 37 0.061
nucleoside monophosphate catabolic process GO:0009125 39 0.061
actin filament based process GO:0030029 220 0.059
positive regulation of neuron differentiation GO:0045666 26 0.059
regulation of cellular amino acid metabolic process GO:0006521 0 0.059
chromatin modification GO:0016568 147 0.058
regulation of cellular component movement GO:0051270 42 0.058
positive regulation of phosphorylation GO:0042327 87 0.057
intracellular signal transduction GO:0035556 300 0.057
dna metabolic process GO:0006259 227 0.056
regulation of cell division GO:0051302 72 0.056
regulation of protein modification process GO:0031399 112 0.056
feeding behavior GO:0007631 50 0.056
tissue homeostasis GO:0001894 36 0.056
learning or memory GO:0007611 141 0.055
response to starvation GO:0042594 97 0.055
cellular response to organic substance GO:0071310 132 0.055
positive regulation of response to external stimulus GO:0032103 44 0.055
sex differentiation GO:0007548 81 0.055
larval development GO:0002164 104 0.054
cellular response to lipid GO:0071396 20 0.054
cellular macromolecule localization GO:0070727 220 0.054
response to oxidative stress GO:0006979 86 0.053
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.053
positive regulation of phosphate metabolic process GO:0045937 139 0.052
organonitrogen compound metabolic process GO:1901564 318 0.052
notch signaling pathway GO:0007219 120 0.051
cellular response to oxygen containing compound GO:1901701 79 0.051
regulation of mapk cascade GO:0043408 92 0.051
protein deubiquitination GO:0016579 17 0.051
centrosome organization GO:0051297 163 0.051
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.051
positive regulation of biosynthetic process GO:0009891 316 0.051
Mouse
single organism intracellular transport GO:1902582 207 0.050
negative regulation of immune system process GO:0002683 50 0.050
positive regulation of catalytic activity GO:0043085 118 0.049
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.049
cognition GO:0050890 141 0.049
atp metabolic process GO:0046034 49 0.049
homeostatic process GO:0042592 199 0.048
regulation of nuclear division GO:0051783 58 0.047
cellular response to organic cyclic compound GO:0071407 32 0.047
autophagic vacuole assembly GO:0000045 2 0.046
positive regulation of dendrite morphogenesis GO:0050775 9 0.046
phosphorylation GO:0016310 294 0.046
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.046
regulation of phosphate metabolic process GO:0019220 210 0.045
anatomical structure homeostasis GO:0060249 97 0.045
regulation of cellular amine metabolic process GO:0033238 3 0.045
response to reactive oxygen species GO:0000302 24 0.045
negative regulation of cell communication GO:0010648 223 0.044
regulation of terminal button organization GO:2000331 11 0.044
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.043
regulation of transport GO:0051049 181 0.043
regulation of cell cycle process GO:0010564 181 0.043
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.041
response to organic cyclic compound GO:0014070 89 0.040
ribonucleoside monophosphate metabolic process GO:0009161 51 0.040
stem cell development GO:0048864 79 0.040
telencephalon development GO:0021537 2 0.040
biological adhesion GO:0022610 138 0.040
chromatin organization GO:0006325 207 0.040
axis specification GO:0009798 167 0.040
epithelium migration GO:0090132 148 0.039
signal transduction by phosphorylation GO:0023014 107 0.038
neurotransmitter transport GO:0006836 37 0.038
purine ribonucleotide metabolic process GO:0009150 145 0.037
embryonic axis specification GO:0000578 107 0.037
apoptotic signaling pathway GO:0097190 27 0.037
regulation of mitotic cell cycle GO:0007346 190 0.037
regulation of catalytic activity GO:0050790 185 0.037
nucleoside monophosphate metabolic process GO:0009123 52 0.036
epithelial cell development GO:0002064 274 0.036
regulation of axon extension GO:0030516 8 0.036
regulation of apoptotic signaling pathway GO:2001233 10 0.036
purine nucleoside triphosphate catabolic process GO:0009146 108 0.036
regulation of cellular component biogenesis GO:0044087 201 0.036
regulation of neural precursor cell proliferation GO:2000177 35 0.036
organophosphate catabolic process GO:0046434 112 0.036
regulation of developmental growth GO:0048638 174 0.035
response to heat GO:0009408 63 0.035
establishment of cell polarity GO:0030010 40 0.034
glial cell development GO:0021782 27 0.034
spindle localization GO:0051653 22 0.034
retina development in camera type eye GO:0060041 4 0.034
microtubule based movement GO:0007018 51 0.034
rna localization GO:0006403 115 0.034
signal transduction in response to dna damage GO:0042770 3 0.033
ribonucleoside monophosphate catabolic process GO:0009158 39 0.033
branching involved in open tracheal system development GO:0060446 45 0.033
regulation of molecular function GO:0065009 217 0.033
cellular amine metabolic process GO:0044106 12 0.032
regulation of response to nutrient levels GO:0032107 18 0.032
intracellular steroid hormone receptor signaling pathway GO:0030518 12 0.032
purine nucleoside monophosphate metabolic process GO:0009126 50 0.032
negative regulation of signal transduction GO:0009968 206 0.031
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.030
developmental growth involved in morphogenesis GO:0060560 65 0.030
Zebrafish
regulation of epithelial cell proliferation GO:0050678 4 0.029
purine nucleoside metabolic process GO:0042278 127 0.029
mrna splicing via spliceosome GO:0000398 73 0.029
camera type eye development GO:0043010 4 0.029
positive regulation of cellular biosynthetic process GO:0031328 316 0.029
Mouse
negative regulation of neuromuscular synaptic transmission GO:1900074 7 0.029
establishment of spindle orientation GO:0051294 18 0.029
positive regulation of intracellular signal transduction GO:1902533 116 0.028
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.028
wnt signaling pathway GO:0016055 98 0.028
photoreceptor cell differentiation GO:0046530 170 0.028
asymmetric cell division GO:0008356 37 0.028
cytoskeleton dependent intracellular transport GO:0030705 44 0.028
muscle cell differentiation GO:0042692 103 0.028
positive regulation of ion transmembrane transporter activity GO:0032414 4 0.028
mitotic sister chromatid segregation GO:0000070 87 0.028
regulation of system process GO:0044057 36 0.027
regulation of notch signaling pathway GO:0008593 100 0.027
determination of bilateral symmetry GO:0009855 13 0.027
cellular response to ketone GO:1901655 17 0.027
muscle organ development GO:0007517 127 0.027
cellular response to endogenous stimulus GO:0071495 80 0.026
regulation of transferase activity GO:0051338 58 0.026
extrinsic apoptotic signaling pathway GO:0097191 1 0.026
establishment of spindle localization GO:0051293 22 0.026
regulation of phosphatase activity GO:0010921 3 0.026
positive regulation of gene expression GO:0010628 290 0.025
Mouse
carbohydrate derivative metabolic process GO:1901135 217 0.025
germarium derived female germ line cyst formation GO:0030727 42 0.025
positive regulation of apoptotic process GO:0043065 47 0.025
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.025
endomembrane system organization GO:0010256 119 0.025
negative regulation of response to oxidative stress GO:1902883 1 0.025
positive regulation of phosphorus metabolic process GO:0010562 139 0.025
blood circulation GO:0008015 26 0.025
regulation of cell size GO:0008361 63 0.025
male gamete generation GO:0048232 201 0.025
aging GO:0007568 143 0.024
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.024
multicellular organismal aging GO:0010259 140 0.024
macromolecule catabolic process GO:0009057 161 0.024
regulation of localization GO:0032879 275 0.024
regulation of actin filament based process GO:0032970 42 0.023
spermatid development GO:0007286 98 0.023
cytoplasmic transport GO:0016482 130 0.023
regulation of blood circulation GO:1903522 21 0.023
larval behavior GO:0030537 42 0.023
morphogenesis of a branching epithelium GO:0061138 45 0.023
stem cell proliferation GO:0072089 88 0.023
cellular catabolic process GO:0044248 372 0.022
morphogenesis of a branching structure GO:0001763 45 0.022
response to lipopolysaccharide GO:0032496 4 0.022
skeletal muscle organ development GO:0060538 48 0.022
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.022
cell type specific apoptotic process GO:0097285 38 0.022
rhabdomere development GO:0042052 38 0.022
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
Mouse
mitotic nuclear division GO:0007067 213 0.022
embryonic organ development GO:0048568 50 0.021
positive regulation of cell proliferation GO:0008284 47 0.021
synapse maturation GO:0060074 7 0.021
multi organism behavior GO:0051705 175 0.021
organ growth GO:0035265 56 0.021
gland morphogenesis GO:0022612 145 0.021
protein oligomerization GO:0051259 16 0.020
spinal cord development GO:0021510 1 0.020
peptidyl threonine modification GO:0018210 3 0.020
cell fate specification GO:0001708 71 0.020
cytokinetic cell separation GO:0000920 1 0.020
regulation of transmembrane transporter activity GO:0022898 6 0.020
blastoderm segmentation GO:0007350 159 0.020
catabolic process GO:0009056 409 0.020
digestive tract development GO:0048565 149 0.020
purine nucleotide metabolic process GO:0006163 146 0.020
intraspecies interaction between organisms GO:0051703 4 0.019
response to sterol GO:0036314 34 0.019
defense response GO:0006952 300 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.019
Human
cellular response to oxidative stress GO:0034599 28 0.019
regulation of neuromuscular synaptic transmission GO:1900073 15 0.019
heart morphogenesis GO:0003007 32 0.019
myotube cell development GO:0014904 3 0.019
regulation of cell growth GO:0001558 43 0.019
axon regeneration GO:0031103 8 0.019
purine nucleoside monophosphate catabolic process GO:0009128 38 0.018
positive regulation of organelle organization GO:0010638 65 0.018
positive regulation of protein metabolic process GO:0051247 128 0.018
purine nucleoside catabolic process GO:0006152 112 0.018
germ line stem cell division GO:0042078 25 0.018
wing disc morphogenesis GO:0007472 344 0.018
cortical cytoskeleton organization GO:0030865 29 0.018
regulation of cell proliferation GO:0042127 163 0.018
developmental maturation GO:0021700 172 0.018
mitotic cell cycle phase transition GO:0044772 138 0.018
regulation of translation GO:0006417 56 0.018
purine ribonucleoside catabolic process GO:0046130 112 0.017
photoreceptor cell development GO:0042461 96 0.017
chromosome separation GO:0051304 42 0.017
nucleoside phosphate catabolic process GO:1901292 110 0.017
regulation of cellular localization GO:0060341 136 0.017
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.017
endoderm formation GO:0001706 3 0.017
regulation of programmed cell death GO:0043067 152 0.017
action potential GO:0001508 13 0.016
morphogenesis of embryonic epithelium GO:0016331 94 0.016
negative regulation of signal transduction by p53 class mediator GO:1901797 1 0.016
developmental cell growth GO:0048588 52 0.016
Zebrafish
startle response GO:0001964 16 0.016
response to external biotic stimulus GO:0043207 293 0.016
glycosyl compound metabolic process GO:1901657 127 0.016
detection of external stimulus GO:0009581 66 0.016
negative regulation of cellular response to oxidative stress GO:1900408 1 0.016
regulation of g protein coupled receptor protein signaling pathway GO:0008277 23 0.016
ubiquitin dependent protein catabolic process GO:0006511 78 0.016
oocyte development GO:0048599 124 0.016
regulation of locomotion GO:0040012 42 0.016
endocytosis GO:0006897 310 0.016
regulation of protein deacetylation GO:0090311 2 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
cell maturation GO:0048469 144 0.015
regulation of apoptotic process GO:0042981 130 0.015
actin cytoskeleton organization GO:0030036 206 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.014
positive regulation of endocytosis GO:0045807 22 0.014
rna splicing GO:0008380 83 0.014
Human
camera type eye morphogenesis GO:0048593 2 0.014
negative regulation of programmed cell death GO:0043069 72 0.014
regulation of cellular response to oxidative stress GO:1900407 4 0.014
single organism membrane organization GO:0044802 93 0.014
mapk cascade GO:0000165 107 0.014
dna methylation GO:0006306 4 0.014
regulation of axonogenesis GO:0050770 32 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
epithelial tube morphogenesis GO:0060562 88 0.013
positive regulation of cell migration GO:0030335 2 0.013
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.013
negative regulation of neuron death GO:1901215 18 0.013
protein localization GO:0008104 284 0.013
regulation of stress activated mapk cascade GO:0032872 41 0.013
intrinsic apoptotic signaling pathway GO:0097193 16 0.013
positive regulation of stem cell proliferation GO:2000648 8 0.012
developmental programmed cell death GO:0010623 138 0.012
peptidyl amino acid modification GO:0018193 105 0.012
anterior posterior axis specification GO:0009948 109 0.012
stress activated protein kinase signaling cascade GO:0031098 55 0.012
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.012
regulation of protein ubiquitination GO:0031396 22 0.012
apoptotic process GO:0006915 159 0.012
response to biotic stimulus GO:0009607 294 0.012
reproductive structure development GO:0048608 74 0.012
negative regulation of cell cycle phase transition GO:1901988 103 0.012
heterocycle catabolic process GO:0046700 166 0.012
negative regulation of neuron differentiation GO:0045665 16 0.012
mitotic g2 dna damage checkpoint GO:0007095 69 0.012
cytoskeleton dependent cytokinesis GO:0061640 81 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
tissue migration GO:0090130 155 0.012
amine metabolic process GO:0009308 12 0.012
retina morphogenesis in camera type eye GO:0060042 2 0.012
salivary gland morphogenesis GO:0007435 145 0.012
specification of symmetry GO:0009799 13 0.012
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
Human
positive regulation of protein phosphorylation GO:0001934 34 0.011
response to decreased oxygen levels GO:0036293 58 0.011
neuroblast proliferation GO:0007405 74 0.011
exocrine system development GO:0035272 162 0.011
sister chromatid segregation GO:0000819 92 0.011
atp catabolic process GO:0006200 38 0.011
positive regulation of cell projection organization GO:0031346 29 0.011

TBPH disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.308
Human
motor neuron disease DOID:231 0 0.059
Human
central nervous system disease DOID:331 0 0.059
Human
neurodegenerative disease DOID:1289 0 0.059
Human
nervous system disease DOID:863 0 0.059
Human
disease of cellular proliferation DOID:14566 0 0.038
amyotrophic lateral sclerosis DOID:332 0 0.019
Human
disease of mental health DOID:150 0 0.016
developmental disorder of mental health DOID:0060037 0 0.016
specific developmental disorder DOID:0060038 0 0.016
intellectual disability DOID:1059 0 0.016
neuromuscular disease DOID:440 0 0.012
charcot marie tooth disease DOID:10595 0 0.012
neuropathy DOID:870 0 0.012
cancer DOID:162 0 0.012
organ system cancer DOID:0050686 0 0.012