Drosophila melanogaster

53 known processes

AP-50 (Dmel_CG7057)

CG7057 gene product from transcript CG7057-RB

(Aliases: anon-EST:Posey50,AP-2mu,cg7057,mu2,Dmel\CG7057,AP50,CG7057,Dmu2,anon-WO0172774.104)

AP-50 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
germarium derived egg chamber formation GO:0007293 101 0.989
germarium derived female germ line cyst formation GO:0030727 42 0.817
female germ line cyst formation GO:0048135 42 0.445
germ line cyst formation GO:0048134 44 0.354
ovarian follicle cell development GO:0030707 248 0.351
columnar cuboidal epithelial cell development GO:0002066 249 0.320
positive regulation of macromolecule metabolic process GO:0010604 405 0.318
developmental growth GO:0048589 280 0.252
intracellular transport GO:0046907 228 0.239
vesicle mediated transport GO:0016192 381 0.225
epithelial cell development GO:0002064 274 0.181
endosomal vesicle fusion GO:0034058 4 0.170
morphogenesis of follicular epithelium GO:0016333 36 0.129
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.123
cellular protein modification process GO:0006464 438 0.107
positive regulation of rna metabolic process GO:0051254 271 0.105
larval development GO:0002164 104 0.103
regulation of cell morphogenesis GO:0022604 163 0.101
regulation of notch signaling pathway GO:0008593 100 0.100
regulation of vesicle mediated transport GO:0060627 59 0.097
catabolic process GO:0009056 409 0.095
dorsal ventral pattern formation GO:0009953 133 0.091
single organism intracellular transport GO:1902582 207 0.090
tissue morphogenesis GO:0048729 297 0.088
regionalization GO:0003002 416 0.085
growth GO:0040007 359 0.083
purine ribonucleotide metabolic process GO:0009150 145 0.074
positive regulation of nucleic acid templated transcription GO:1903508 266 0.073
transcription from rna polymerase ii promoter GO:0006366 368 0.073
response to external biotic stimulus GO:0043207 293 0.073
regulation of intracellular signal transduction GO:1902531 236 0.071
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.071
protein modification process GO:0036211 438 0.068
biological adhesion GO:0022610 138 0.064
regulation of cellular catabolic process GO:0031329 157 0.061
positive regulation of gene expression GO:0010628 290 0.061
ovarian follicle cell migration GO:0007297 121 0.060
regulation of cell differentiation GO:0045595 302 0.060
cell proliferation GO:0008283 299 0.060
organic substance transport GO:0071702 257 0.058
cellular protein complex assembly GO:0043623 71 0.057
intracellular signal transduction GO:0035556 300 0.055
regulation of transport GO:0051049 181 0.054
positive regulation of transcription dna templated GO:0045893 266 0.053
negative regulation of multicellular organismal process GO:0051241 142 0.052
imaginal disc derived appendage morphogenesis GO:0035114 395 0.052
regulation of protein metabolic process GO:0051246 256 0.051
compound eye development GO:0048749 307 0.050
eye development GO:0001654 323 0.048
regulation of cell shape GO:0008360 113 0.048
developmental maturation GO:0021700 172 0.048
positive regulation of cellular biosynthetic process GO:0031328 316 0.047
negative regulation of signal transduction GO:0009968 206 0.047
macromolecular complex assembly GO:0065003 256 0.046
proteolysis GO:0006508 192 0.044
morphogenesis of an epithelium GO:0002009 276 0.044
establishment of localization in cell GO:0051649 402 0.043
positive regulation of cell communication GO:0010647 250 0.043
organelle fission GO:0048285 340 0.043
ubiquitin dependent protein catabolic process GO:0006511 78 0.042
phosphorylation GO:0016310 294 0.042
positive regulation of signaling GO:0023056 243 0.041
regulation of multicellular organismal development GO:2000026 414 0.041
membrane organization GO:0061024 112 0.040
Human
regulation of endocytosis GO:0030100 37 0.040
apoptotic process involved in development GO:1902742 20 0.039
protein catabolic process GO:0030163 101 0.039
chromosome segregation GO:0007059 157 0.039
cytoskeleton dependent cytokinesis GO:0061640 81 0.038
positive regulation of cellular component organization GO:0051130 156 0.038
modification dependent macromolecule catabolic process GO:0043632 79 0.038
positive regulation of protein metabolic process GO:0051247 128 0.038
cytokinesis GO:0000910 90 0.038
compound eye morphogenesis GO:0001745 249 0.037
male gamete generation GO:0048232 201 0.037
negative regulation of signaling GO:0023057 219 0.037
regulation of cell development GO:0060284 215 0.036
response to biotic stimulus GO:0009607 294 0.036
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.036
cellular protein localization GO:0034613 160 0.036
Human
macromolecule catabolic process GO:0009057 161 0.035
response to other organism GO:0051707 293 0.035
positive regulation of biosynthetic process GO:0009891 316 0.034
programmed cell death GO:0012501 257 0.034
cell cell signaling involved in cell fate commitment GO:0045168 210 0.033
wing disc morphogenesis GO:0007472 344 0.033
regulation of localization GO:0032879 275 0.032
Human
positive regulation of response to stimulus GO:0048584 323 0.032
death GO:0016265 284 0.031
cellular response to external stimulus GO:0071496 66 0.031
phagocytosis GO:0006909 215 0.031
ion transmembrane transport GO:0034220 122 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.029
actin cytoskeleton organization GO:0030036 206 0.028
response to radiation GO:0009314 155 0.028
epithelial cell differentiation GO:0030855 322 0.026
small gtpase mediated signal transduction GO:0007264 88 0.026
regulation of cellular amine metabolic process GO:0033238 3 0.026
regulation of catalytic activity GO:0050790 185 0.025
negative regulation of nucleic acid templated transcription GO:1903507 240 0.025
regulation of purine nucleotide metabolic process GO:1900542 62 0.025
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.025
carbohydrate derivative metabolic process GO:1901135 217 0.025
endocytosis GO:0006897 310 0.025
endosomal transport GO:0016197 44 0.024
positive regulation of signal transduction GO:0009967 223 0.024
positive regulation of transport GO:0051050 92 0.024
organic substance catabolic process GO:1901575 308 0.024
epithelium migration GO:0090132 148 0.024
eye morphogenesis GO:0048592 260 0.024
regulation of organelle organization GO:0033043 196 0.024
stem cell differentiation GO:0048863 117 0.023
protein ubiquitination GO:0016567 70 0.023
cellular macromolecule catabolic process GO:0044265 136 0.023
blastoderm segmentation GO:0007350 159 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.023
small molecule metabolic process GO:0044281 305 0.023
dephosphorylation GO:0016311 51 0.022
cell motility GO:0048870 251 0.022
regulation of mapk cascade GO:0043408 92 0.022
negative regulation of cell communication GO:0010648 223 0.022
regulation of catabolic process GO:0009894 170 0.022
tissue migration GO:0090130 155 0.022
ion transport GO:0006811 145 0.022
cellular catabolic process GO:0044248 372 0.022
oocyte development GO:0048599 124 0.021
negative regulation of biosynthetic process GO:0009890 277 0.021
positive regulation of molecular function GO:0044093 136 0.021
sensory organ morphogenesis GO:0090596 260 0.021
macromolecular complex disassembly GO:0032984 37 0.020
regulation of ras protein signal transduction GO:0046578 93 0.020
organic acid transport GO:0015849 18 0.020
ras protein signal transduction GO:0007265 88 0.019
purine nucleoside catabolic process GO:0006152 112 0.019
regulation of cellular component biogenesis GO:0044087 201 0.019
notch signaling pathway GO:0007219 120 0.018
negative regulation of cell proliferation GO:0008285 69 0.018
regulation of developmental growth GO:0048638 174 0.018
developmental programmed cell death GO:0010623 138 0.018
cellular protein catabolic process GO:0044257 83 0.018
regulation of response to external stimulus GO:0032101 115 0.018
photoreceptor cell development GO:0042461 96 0.018
cellular macromolecular complex assembly GO:0034622 153 0.018
positive regulation of intracellular signal transduction GO:1902533 116 0.017
protein complex assembly GO:0006461 200 0.017
negative regulation of rna metabolic process GO:0051253 251 0.017
transmembrane transport GO:0055085 139 0.017
purine nucleotide metabolic process GO:0006163 146 0.017
positive regulation of rna biosynthetic process GO:1902680 266 0.017
establishment of protein localization GO:0045184 163 0.017
protein polymerization GO:0051258 42 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.016
apoptotic process GO:0006915 159 0.016
positive regulation of phosphate metabolic process GO:0045937 139 0.016
intracellular protein transport GO:0006886 104 0.016
negative regulation of protein metabolic process GO:0051248 85 0.015
molting cycle GO:0042303 56 0.015
regulation of cellular component size GO:0032535 98 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
regulation of anatomical structure size GO:0090066 163 0.015
cellular ketone metabolic process GO:0042180 24 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
nitrogen compound transport GO:0071705 85 0.014
neuromuscular junction development GO:0007528 149 0.014
regulation of growth GO:0040008 233 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.014
eye antennal disc development GO:0035214 60 0.014
purine ribonucleoside catabolic process GO:0046130 112 0.014
regulation of locomotion GO:0040012 42 0.014
atp metabolic process GO:0046034 49 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
regulation of phosphate metabolic process GO:0019220 210 0.013
regulation of cellular localization GO:0060341 136 0.013
Human
negative regulation of developmental process GO:0051093 201 0.013
modification dependent protein catabolic process GO:0019941 78 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
spermatogenesis GO:0007283 200 0.013
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.013
actin filament organization GO:0007015 126 0.013
nuclear division GO:0000280 332 0.013
cytoplasmic transport GO:0016482 130 0.013
response to organic substance GO:0010033 284 0.013
positive regulation of catabolic process GO:0009896 105 0.013
synaptic transmission GO:0007268 288 0.013
response to extracellular stimulus GO:0009991 116 0.013
protein complex biogenesis GO:0070271 201 0.013
actin filament based process GO:0030029 220 0.013
regulation of epithelial cell proliferation GO:0050678 4 0.013
synapse organization GO:0050808 196 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.012
regulation of immune system process GO:0002682 176 0.012
establishment or maintenance of cell polarity GO:0007163 167 0.012
rna localization GO:0006403 115 0.012
segmentation GO:0035282 207 0.012
regulation of hemocyte proliferation GO:0035206 37 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
cellular response to organic substance GO:0071310 132 0.011
positive regulation of protein complex assembly GO:0031334 22 0.011
cell adhesion GO:0007155 136 0.011
organophosphate metabolic process GO:0019637 195 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
filopodium assembly GO:0046847 33 0.011
negative regulation of cellular metabolic process GO:0031324 382 0.011
detection of external stimulus GO:0009581 66 0.011
heterocycle catabolic process GO:0046700 166 0.010
nurse cell apoptotic process GO:0045476 17 0.010
purine ribonucleoside metabolic process GO:0046128 127 0.010
glycosyl compound metabolic process GO:1901657 127 0.010
regulation of anatomical structure morphogenesis GO:0022603 242 0.010
regulation of nervous system development GO:0051960 248 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010
cell division GO:0051301 248 0.010
appendage morphogenesis GO:0035107 397 0.010
regulation of cellular ketone metabolic process GO:0010565 3 0.010

AP-50 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org