Drosophila melanogaster

43 known processes

sob (Dmel_CG3242)

sister of odd and bowl

(Aliases: org1,CG3242,Dmel\CG3242,Sob)

sob biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
leg disc development GO:0035218 92 0.876
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.596
Zebrafish Mouse Fly
positive regulation of transcription dna templated GO:0045893 266 0.567
Mouse Fly
negative regulation of rna metabolic process GO:0051253 251 0.550
Zebrafish Mouse Fly
regionalization GO:0003002 416 0.519
imaginal disc derived appendage morphogenesis GO:0035114 395 0.480
eye development GO:0001654 323 0.436
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.423
Zebrafish Mouse Fly
sensory organ morphogenesis GO:0090596 260 0.421
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.418
Mouse Fly
positive regulation of nucleic acid templated transcription GO:1903508 266 0.406
Mouse Fly
regulation of cell differentiation GO:0045595 302 0.368
Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.358
Mouse Fly
appendage morphogenesis GO:0035107 397 0.349
muscle structure development GO:0061061 224 0.349
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.300
Mouse Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.289
Mouse Fly
imaginal disc derived appendage development GO:0048737 399 0.285
positive regulation of gene expression GO:0010628 290 0.272
Mouse Fly
eye morphogenesis GO:0048592 260 0.270
negative regulation of rna biosynthetic process GO:1902679 240 0.269
Zebrafish Mouse Fly
negative regulation of biosynthetic process GO:0009890 277 0.258
Zebrafish Mouse Fly
post embryonic appendage morphogenesis GO:0035120 385 0.249
positive regulation of rna metabolic process GO:0051254 271 0.244
Mouse Fly
negative regulation of transcription dna templated GO:0045892 237 0.240
Zebrafish Mouse Fly
imaginal disc pattern formation GO:0007447 91 0.234
blastoderm segmentation GO:0007350 159 0.228
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.223
Zebrafish Mouse Fly
epithelial cell differentiation GO:0030855 322 0.223
Zebrafish Mouse
imaginal disc derived wing morphogenesis GO:0007476 337 0.219
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.216
Zebrafish Mouse Fly
malpighian tubule development GO:0072002 64 0.196
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.190
Mouse Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.188
Mouse Fly
transcription from rna polymerase ii promoter GO:0006366 368 0.183
Zebrafish Mouse Fly
chemotaxis GO:0006935 249 0.181
segmentation GO:0035282 207 0.176
stem cell differentiation GO:0048863 117 0.165
Zebrafish Mouse
central nervous system development GO:0007417 201 0.165
negative regulation of nucleic acid templated transcription GO:1903507 240 0.164
Zebrafish Mouse Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.158
Mouse Fly
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.156
Zebrafish Mouse Fly
segment specification GO:0007379 33 0.153
Mouse
circulatory system development GO:0072359 82 0.150
Zebrafish Mouse
imaginal disc derived leg morphogenesis GO:0007480 80 0.146
wing disc morphogenesis GO:0007472 344 0.142
negative regulation of cellular biosynthetic process GO:0031327 277 0.141
Zebrafish Mouse Fly
epithelial cell development GO:0002064 274 0.140
negative regulation of gene expression GO:0010629 387 0.139
Zebrafish Mouse Fly
leg disc morphogenesis GO:0007478 80 0.136
cell cell signaling involved in cell fate commitment GO:0045168 210 0.130
Fly
positive regulation of biosynthetic process GO:0009891 316 0.128
Mouse Fly
renal system development GO:0072001 72 0.127
Human Zebrafish Mouse Fly
columnar cuboidal epithelial cell development GO:0002066 249 0.118
neuron projection guidance GO:0097485 241 0.117
cardiovascular system development GO:0072358 82 0.113
Zebrafish Mouse
axonogenesis GO:0007409 290 0.112
regulation of cell fate specification GO:0042659 27 0.104
imaginal disc derived leg segmentation GO:0036011 26 0.104
cell motility GO:0048870 251 0.102
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.101
Zebrafish Mouse Fly
cell fate specification GO:0001708 71 0.101
compound eye development GO:0048749 307 0.100
regulation of cell fate commitment GO:0010453 29 0.099
anterior posterior pattern specification GO:0009952 136 0.097
Mouse Fly
head development GO:0060322 135 0.096
Mouse
axon guidance GO:0007411 233 0.095
dorsal ventral pattern formation GO:0009953 133 0.094
cardiocyte differentiation GO:0035051 29 0.090
digestive tract development GO:0048565 149 0.089
Human Mouse Fly
compound eye morphogenesis GO:0001745 249 0.088
embryonic pattern specification GO:0009880 174 0.083
Fly
negative regulation of multicellular organismal process GO:0051241 142 0.082
Mouse
tube development GO:0035295 244 0.081
Human Zebrafish Mouse Fly
axon development GO:0061564 297 0.081
renal tubule development GO:0061326 64 0.080
Zebrafish Mouse Fly
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.078
chorion containing eggshell formation GO:0007304 105 0.077
eye antennal disc development GO:0035214 60 0.076
defense response GO:0006952 300 0.073
digestive tract morphogenesis GO:0048546 127 0.068
Human Mouse Fly
ovarian follicle cell development GO:0030707 248 0.066
regulation of nervous system development GO:0051960 248 0.066
regulation of cell development GO:0060284 215 0.064
chaeta development GO:0022416 97 0.063
cell migration GO:0016477 238 0.062
embryonic development via the syncytial blastoderm GO:0001700 148 0.061
embryonic organ development GO:0048568 50 0.060
Mouse
cellular macromolecule localization GO:0070727 220 0.060
cardioblast differentiation GO:0010002 20 0.060
regulation of neurogenesis GO:0050767 158 0.059
wing disc pattern formation GO:0035222 66 0.059
negative regulation of cellular metabolic process GO:0031324 382 0.059
Zebrafish Mouse Fly
heart development GO:0007507 82 0.057
Mouse
morphogenesis of an epithelium GO:0002009 276 0.056
Mouse Fly
gland development GO:0048732 191 0.056
cardioblast cell fate commitment GO:0042684 14 0.054
cell death GO:0008219 279 0.053
Mouse
embryonic hindgut morphogenesis GO:0048619 48 0.053
Fly
mesoderm development GO:0007498 78 0.052
Zebrafish Mouse
taxis GO:0042330 304 0.051
tube morphogenesis GO:0035239 191 0.050
Human Mouse Fly
regulation of embryonic development GO:0045995 68 0.050
Human Mouse
homeostatic process GO:0042592 199 0.050
cardiac cell fate commitment GO:0060911 17 0.049
neuron recognition GO:0008038 101 0.048
camera type eye development GO:0043010 4 0.048
Mouse
mushroom body development GO:0016319 70 0.048
tissue morphogenesis GO:0048729 297 0.047
Mouse Fly
localization of cell GO:0051674 257 0.047
somatic muscle development GO:0007525 66 0.047
stem cell proliferation GO:0072089 88 0.046
Mouse
mesenchymal cell differentiation GO:0048762 1 0.046
Zebrafish Mouse
appendage development GO:0048736 401 0.046
regulation of cellular component size GO:0032535 98 0.046
eggshell formation GO:0030703 105 0.045
regulation of epithelial cell proliferation GO:0050678 4 0.045
Mouse
embryo development ending in birth or egg hatching GO:0009792 152 0.045
Mouse
body morphogenesis GO:0010171 2 0.043
cellular protein localization GO:0034613 160 0.042
terminal region determination GO:0007362 25 0.041
Fly
brain development GO:0007420 120 0.041
programmed cell death GO:0012501 257 0.041
Mouse
response to external biotic stimulus GO:0043207 293 0.041
regulation of neuron projection development GO:0010975 69 0.041
response to biotic stimulus GO:0009607 294 0.040
growth GO:0040007 359 0.040
determination of imaginal disc primordium GO:0007445 11 0.040
epithelial tube morphogenesis GO:0060562 88 0.039
Mouse Fly
response to oxygen containing compound GO:1901700 200 0.038
Mouse
retina development in camera type eye GO:0060041 4 0.037
renal tubule morphogenesis GO:0061333 44 0.037
Mouse Fly
negative regulation of cell differentiation GO:0045596 143 0.037
Mouse
regulation of immune system process GO:0002682 176 0.037
axis specification GO:0009798 167 0.036
Fly
cell proliferation GO:0008283 299 0.036
Mouse
connective tissue development GO:0061448 3 0.036
Mouse
protein localization GO:0008104 284 0.034
anterior posterior pattern specification imaginal disc GO:0007448 16 0.034
chorion containing eggshell pattern formation GO:0030381 11 0.034
forebrain development GO:0030900 2 0.034
neurological system process GO:0050877 358 0.033
urogenital system development GO:0001655 72 0.032
Human Zebrafish Mouse Fly
establishment of localization in cell GO:0051649 402 0.032
regulation of anatomical structure size GO:0090066 163 0.032
gastrulation GO:0007369 70 0.032
Human Mouse
immune response activating signal transduction GO:0002757 2 0.032
adult behavior GO:0030534 137 0.032
limb morphogenesis GO:0035108 1 0.032
Mouse
regulation of cell death GO:0010941 173 0.031
Mouse
organic substance transport GO:0071702 257 0.031
immune response GO:0006955 246 0.031
innate immune response GO:0045087 144 0.030
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.030
sensory perception GO:0007600 196 0.030
neuron fate commitment GO:0048663 50 0.030
regulation of localization GO:0032879 275 0.029
regulation of multicellular organismal development GO:2000026 414 0.029
Human Mouse
nephron morphogenesis GO:0072028 3 0.029
Mouse
positive regulation of protein metabolic process GO:0051247 128 0.029
regulation of developmental growth GO:0048638 174 0.028
positive regulation of response to stimulus GO:0048584 323 0.028
limb development GO:0060173 1 0.028
Mouse
nephron tubule morphogenesis GO:0072078 3 0.028
Mouse
response to other organism GO:0051707 293 0.028
kidney morphogenesis GO:0060993 3 0.027
Mouse
kidney development GO:0001822 3 0.027
Human Zebrafish Mouse
lateral inhibition GO:0046331 206 0.027
Fly
pattern recognition receptor signaling pathway GO:0002221 2 0.027
chaeta morphogenesis GO:0008407 42 0.027
cellular component assembly involved in morphogenesis GO:0010927 151 0.027
anatomical structure homeostasis GO:0060249 97 0.027
establishment or maintenance of cell polarity GO:0007163 167 0.027
malpighian tubule morphogenesis GO:0007443 44 0.027
Fly
nephron tubule development GO:0072080 3 0.027
Zebrafish Mouse
regulation of protein metabolic process GO:0051246 256 0.026
organelle fission GO:0048285 340 0.026
outflow tract morphogenesis GO:0003151 4 0.026
formation of anatomical boundary GO:0048859 37 0.026
vesicle mediated transport GO:0016192 381 0.025
embryonic heart tube development GO:0035050 22 0.025
regulation of phosphorus metabolic process GO:0051174 210 0.025
antennal development GO:0007469 25 0.025
organ formation GO:0048645 39 0.024
regulation of cell proliferation GO:0042127 163 0.024
Mouse
positive regulation of cell motility GO:2000147 3 0.024
immune response regulating signaling pathway GO:0002764 2 0.024
regulation of neuron differentiation GO:0045664 103 0.024
cell division GO:0051301 248 0.024
carbohydrate derivative biosynthetic process GO:1901137 85 0.024
endomembrane system organization GO:0010256 119 0.024
positive regulation of cell migration GO:0030335 2 0.024
response to bacterium GO:0009617 198 0.023
eye antennal disc morphogenesis GO:0007455 34 0.023
developmental growth involved in morphogenesis GO:0060560 65 0.023
organonitrogen compound metabolic process GO:1901564 318 0.023
single organism cellular localization GO:1902580 180 0.023
carboxylic acid metabolic process GO:0019752 92 0.022
regulation of cell projection organization GO:0031344 92 0.022
kidney epithelium development GO:0072073 3 0.022
Zebrafish Mouse
anterior malpighian tubule development GO:0061327 12 0.022
heart process GO:0003015 37 0.022
cellular response to abiotic stimulus GO:0071214 58 0.022
locomotory behavior GO:0007626 176 0.022
small molecule metabolic process GO:0044281 305 0.022
positive regulation of signal transduction GO:0009967 223 0.021
positive regulation of multicellular organismal process GO:0051240 143 0.021
Human Mouse
mesenchymal cell development GO:0014031 1 0.021
telencephalon development GO:0021537 2 0.021
immune system process GO:0002376 347 0.021
death GO:0016265 284 0.021
Mouse
cilium morphogenesis GO:0060271 39 0.021
regulation of anatomical structure morphogenesis GO:0022603 242 0.020
Human Mouse
single organism intracellular transport GO:1902582 207 0.020
negative regulation of nervous system development GO:0051961 92 0.020
dorsal ventral axis specification GO:0009950 66 0.020
regulation of response to stress GO:0080134 200 0.020
neuroblast differentiation GO:0014016 29 0.020
establishment of protein localization GO:0045184 163 0.020
tripartite regional subdivision GO:0007351 103 0.019
Fly
positive regulation of cellular component organization GO:0051130 156 0.019
endocytosis GO:0006897 310 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
notch signaling pathway GO:0007219 120 0.019
hindgut development GO:0061525 58 0.019
Fly
positive regulation of signaling GO:0023056 243 0.019
amine metabolic process GO:0009308 12 0.019
photoreceptor cell differentiation GO:0046530 170 0.019
stem cell development GO:0048864 79 0.019
positive regulation of phosphorus metabolic process GO:0010562 139 0.019
tissue homeostasis GO:0001894 36 0.019
negative regulation of developmental process GO:0051093 201 0.019
Mouse
nitrogen compound transport GO:0071705 85 0.019
embryonic axis specification GO:0000578 107 0.019
Fly
regulation of cellular localization GO:0060341 136 0.019
appendage segmentation GO:0035285 26 0.018
response to organic cyclic compound GO:0014070 89 0.018
nephron development GO:0072006 3 0.018
Zebrafish Mouse
axon extension GO:0048675 32 0.018
dna templated transcription initiation GO:0006352 25 0.018
defense response to other organism GO:0098542 225 0.018
ameboidal type cell migration GO:0001667 151 0.018
posttranscriptional regulation of gene expression GO:0010608 145 0.018
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.018
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.017
Fly
response to abiotic stimulus GO:0009628 341 0.017
defense response to bacterium GO:0042742 178 0.017
regulation of organelle organization GO:0033043 196 0.017
nephron epithelium development GO:0072009 3 0.017
Zebrafish Mouse
multi organism behavior GO:0051705 175 0.017
phosphorylation GO:0016310 294 0.017
response to nitrogen compound GO:1901698 90 0.017
anterior posterior axis specification embryo GO:0008595 103 0.016
Fly
hindbrain development GO:0030902 2 0.016
negative regulation of neurogenesis GO:0050768 53 0.016
regulation of cell size GO:0008361 63 0.016
single organism behavior GO:0044708 391 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
synapse assembly GO:0007416 143 0.016
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.016
protein transport GO:0015031 155 0.016
sex differentiation GO:0007548 81 0.016
Mouse
compound eye photoreceptor cell differentiation GO:0001751 140 0.016
camera type eye morphogenesis GO:0048593 2 0.015
eye photoreceptor cell differentiation GO:0001754 145 0.015
regulation of growth GO:0040008 233 0.015
chromatin remodeling GO:0006338 72 0.015
intracellular transport GO:0046907 228 0.015
epithelial structure maintenance GO:0010669 17 0.015
cellular response to mechanical stimulus GO:0071260 2 0.015
response to organophosphorus GO:0046683 2 0.015
morphogenesis of a branching structure GO:0001763 45 0.015
photoreceptor cell fate commitment GO:0046552 41 0.015
response to wounding GO:0009611 94 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
cell recognition GO:0008037 102 0.015
hindgut morphogenesis GO:0007442 58 0.015
Fly
neural precursor cell proliferation GO:0061351 75 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
neuroblast proliferation GO:0007405 74 0.015
reproductive structure development GO:0048608 74 0.015
Mouse
innate immune response activating signal transduction GO:0002758 2 0.015
cilium assembly GO:0042384 38 0.015
defense response to fungus GO:0050832 48 0.014
wnt signaling pathway GO:0016055 98 0.014
positive regulation of developmental process GO:0051094 143 0.014
Human Mouse
regulation of notch signaling pathway GO:0008593 100 0.014
endodermal cell differentiation GO:0035987 3 0.014
vesicle organization GO:0016050 44 0.014
cell adhesion GO:0007155 136 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
neuron projection extension GO:1990138 32 0.014
positive regulation of cell communication GO:0010647 250 0.014
larval development GO:0002164 104 0.014
Worm
head segmentation GO:0035287 13 0.014
tissue migration GO:0090130 155 0.014
organic acid metabolic process GO:0006082 103 0.014
proximal distal pattern formation GO:0009954 15 0.014
Mouse
muscle cell differentiation GO:0042692 103 0.014
negative regulation of programmed cell death GO:0043069 72 0.014
Mouse
reproductive system development GO:0061458 74 0.014
Mouse
protein modification process GO:0036211 438 0.014
chromosome segregation GO:0007059 157 0.014
cell maturation GO:0048469 144 0.014
circulatory system process GO:0003013 37 0.013
specification of segmental identity head GO:0007380 11 0.013
neuron fate specification GO:0048665 12 0.013
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
organonitrogen compound biosynthetic process GO:1901566 117 0.013
multicellular organismal homeostasis GO:0048871 41 0.013
regulation of defense response GO:0031347 102 0.013
development of primary sexual characteristics GO:0045137 50 0.013
Mouse
negative regulation of cell death GO:0060548 81 0.013
Mouse
cellular lipid metabolic process GO:0044255 83 0.013
response to alcohol GO:0097305 95 0.013
sex determination GO:0007530 18 0.013
cytoplasmic transport GO:0016482 130 0.013
leg disc proximal distal pattern formation GO:0007479 9 0.013
leg disc pattern formation GO:0035223 11 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
positive regulation of immune system process GO:0002684 68 0.013
antimicrobial humoral response GO:0019730 99 0.013
embryonic morphogenesis GO:0048598 206 0.012
Human Mouse Fly
multi organism reproductive behavior GO:0044705 121 0.012
actin cytoskeleton organization GO:0030036 206 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
positive regulation of cell proliferation GO:0008284 47 0.012
Mouse
carbohydrate metabolic process GO:0005975 82 0.012
response to mechanical stimulus GO:0009612 28 0.012
protein import GO:0017038 55 0.012
regulation of protein modification process GO:0031399 112 0.012
sterol homeostasis GO:0055092 4 0.012
heart morphogenesis GO:0003007 32 0.012
respiratory system development GO:0060541 213 0.012
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.012
cellular catabolic process GO:0044248 372 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
muscle cell fate commitment GO:0042693 14 0.012
regulation of immune response GO:0050776 118 0.012
female sex differentiation GO:0046660 20 0.012
cellular response to organic substance GO:0071310 132 0.012
Mouse
organ growth GO:0035265 56 0.012
morphogenesis of embryonic epithelium GO:0016331 94 0.012
Mouse
open tracheal system development GO:0007424 204 0.012
protein dna complex assembly GO:0065004 63 0.012
positive regulation of immune response GO:0050778 63 0.012
regulation of response to biotic stimulus GO:0002831 63 0.011
intracellular signal transduction GO:0035556 300 0.011
tube formation GO:0035148 21 0.011
Mouse
cytoskeleton dependent cytokinesis GO:0061640 81 0.011
cilium organization GO:0044782 41 0.011
pigmentation GO:0043473 75 0.011
response to organic substance GO:0010033 284 0.011
Mouse
cell growth GO:0016049 108 0.011
protein localization to organelle GO:0033365 82 0.011
axon choice point recognition GO:0016198 26 0.011
chromosome organization GO:0051276 360 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
multi multicellular organism process GO:0044706 123 0.011
multicellular organism growth GO:0035264 46 0.011
phagocytosis GO:0006909 215 0.011
skeletal muscle fiber development GO:0048741 3 0.011
response to fungus GO:0009620 50 0.011
regulation of hemocyte differentiation GO:0045610 22 0.011
intracellular protein transport GO:0006886 104 0.011
cellular protein modification process GO:0006464 438 0.011
protein phosphorylation GO:0006468 169 0.011
endoderm formation GO:0001706 3 0.011
rna localization GO:0006403 115 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
Mouse
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.011
regulation of transport GO:0051049 181 0.011
nephron epithelium morphogenesis GO:0072088 3 0.011
Mouse
lipid metabolic process GO:0006629 121 0.010
establishment of ommatidial planar polarity GO:0042067 49 0.010
development of primary female sexual characteristics GO:0046545 12 0.010
cell fate determination GO:0001709 91 0.010
synapse organization GO:0050808 196 0.010
glycoprotein metabolic process GO:0009100 41 0.010
regulation of organ morphogenesis GO:2000027 78 0.010
response to lipopolysaccharide GO:0032496 4 0.010
embryonic foregut morphogenesis GO:0048617 3 0.010
Fly
convergent extension GO:0060026 2 0.010
hemocyte differentiation GO:0042386 38 0.010
cellular carbohydrate metabolic process GO:0044262 22 0.010
motor neuron axon guidance GO:0008045 58 0.010
regulation of catabolic process GO:0009894 170 0.010
nuclear transport GO:0051169 72 0.010
dendrite development GO:0016358 204 0.010
positive regulation of defense response to bacterium GO:1900426 23 0.010
positive regulation of catabolic process GO:0009896 105 0.010
regulation of imaginal disc derived wing size GO:0044719 20 0.010
negative regulation of growth GO:0045926 84 0.010

sob disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.066
nervous system disease DOID:863 0 0.013
urinary system disease DOID:18 0 0.011