Drosophila melanogaster

8 known processes

Mec2 (Dmel_CG7635)

CG7635 gene product from transcript CG7635-RA

(Aliases: Dmel\CG7635,CG7635,DMec2)

Mec2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
renal filtration GO:0097205 7 0.118
renal system process GO:0003014 12 0.114
response to abiotic stimulus GO:0009628 341 0.076
lateral inhibition GO:0046331 206 0.072
exocrine system development GO:0035272 162 0.057
appendage morphogenesis GO:0035107 397 0.056
organonitrogen compound metabolic process GO:1901564 318 0.054
small molecule metabolic process GO:0044281 305 0.051
cell cell signaling involved in cell fate commitment GO:0045168 210 0.049
epithelial cell development GO:0002064 274 0.048
nephrocyte filtration GO:0097206 7 0.046
nucleobase containing compound catabolic process GO:0034655 165 0.046
vesicle mediated transport GO:0016192 381 0.045
Fly
appendage development GO:0048736 401 0.045
salivary gland development GO:0007431 162 0.045
programmed cell death GO:0012501 257 0.043
nucleoside metabolic process GO:0009116 127 0.043
phosphorylation GO:0016310 294 0.042
defense response to other organism GO:0098542 225 0.041
regulation of molecular function GO:0065009 217 0.041
negative regulation of cell communication GO:0010648 223 0.040
death GO:0016265 284 0.040
catabolic process GO:0009056 409 0.039
carbohydrate derivative catabolic process GO:1901136 118 0.039
cellular catabolic process GO:0044248 372 0.039
negative regulation of signaling GO:0023057 219 0.039
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.039
humoral immune response GO:0006959 117 0.039
digestive system development GO:0055123 149 0.038
cell death GO:0008219 279 0.037
negative regulation of signal transduction GO:0009968 206 0.037
morphogenesis of an epithelium GO:0002009 276 0.037
body morphogenesis GO:0010171 2 0.036
tissue morphogenesis GO:0048729 297 0.036
positive regulation of response to stimulus GO:0048584 323 0.036
negative regulation of response to stimulus GO:0048585 258 0.035
columnar cuboidal epithelial cell development GO:0002066 249 0.035
cellular nitrogen compound catabolic process GO:0044270 165 0.035
response to external biotic stimulus GO:0043207 293 0.034
ion transmembrane transport GO:0034220 122 0.033
morphogenesis of a polarized epithelium GO:0001738 93 0.033
ion transport GO:0006811 145 0.033
negative regulation of cellular metabolic process GO:0031324 382 0.033
cellular response to high light intensity GO:0071486 1 0.033
regulation of catalytic activity GO:0050790 185 0.032
regulation of phosphate metabolic process GO:0019220 210 0.032
regulation of protein metabolic process GO:0051246 256 0.031
heterocycle catabolic process GO:0046700 166 0.031
purine containing compound catabolic process GO:0072523 112 0.031
protein modification process GO:0036211 438 0.030
mesoderm development GO:0007498 78 0.030
regulation of hydrolase activity GO:0051336 97 0.030
intracellular signal transduction GO:0035556 300 0.030
purine nucleoside catabolic process GO:0006152 112 0.029
imaginal disc derived wing morphogenesis GO:0007476 337 0.029
wing disc morphogenesis GO:0007472 344 0.029
negative regulation of gene expression GO:0010629 387 0.029
connective tissue development GO:0061448 3 0.029
response to other organism GO:0051707 293 0.028
salivary gland morphogenesis GO:0007435 145 0.028
regulation of response to stress GO:0080134 200 0.028
epithelial cell differentiation GO:0030855 322 0.028
tube development GO:0035295 244 0.028
camera type eye development GO:0043010 4 0.027
ribonucleoside metabolic process GO:0009119 127 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.026
developmental programmed cell death GO:0010623 138 0.026
malpighian tubule development GO:0072002 64 0.026
purine nucleotide metabolic process GO:0006163 146 0.026
imaginal disc derived appendage morphogenesis GO:0035114 395 0.026
post embryonic appendage morphogenesis GO:0035120 385 0.026
regulation of cellular protein metabolic process GO:0032268 243 0.026
ribonucleoside catabolic process GO:0042454 112 0.025
gland morphogenesis GO:0022612 145 0.025
nucleobase containing small molecule metabolic process GO:0055086 174 0.025
purine ribonucleoside metabolic process GO:0046128 127 0.025
positive regulation of cell communication GO:0010647 250 0.025
kidney development GO:0001822 3 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.025
regulation of phosphorus metabolic process GO:0051174 210 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.025
response to biotic stimulus GO:0009607 294 0.025
imaginal disc derived appendage development GO:0048737 399 0.025
regulation of multicellular organismal development GO:2000026 414 0.025
response to extracellular stimulus GO:0009991 116 0.025
limb development GO:0060173 1 0.024
glycosyl compound metabolic process GO:1901657 127 0.024
ribonucleotide catabolic process GO:0009261 109 0.024
ribonucleotide metabolic process GO:0009259 145 0.023
purine containing compound metabolic process GO:0072521 155 0.023
purine ribonucleoside catabolic process GO:0046130 112 0.023
single organism catabolic process GO:0044712 228 0.023
proteolysis GO:0006508 192 0.023
protein localization GO:0008104 284 0.023
organonitrogen compound catabolic process GO:1901565 128 0.023
positive regulation of molecular function GO:0044093 136 0.023
regulation of cell cycle GO:0051726 291 0.022
aromatic compound catabolic process GO:0019439 166 0.022
purine ribonucleotide metabolic process GO:0009150 145 0.022
ribonucleoside triphosphate catabolic process GO:0009203 108 0.022
leg disc development GO:0035218 92 0.022
nucleoside catabolic process GO:0009164 112 0.022
organic substance transport GO:0071702 257 0.022
regulation of cell death GO:0010941 173 0.022
purine nucleoside triphosphate catabolic process GO:0009146 108 0.022
regulation of phosphorylation GO:0042325 147 0.022
cell division GO:0051301 248 0.022
defense response GO:0006952 300 0.022
positive regulation of catalytic activity GO:0043085 118 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
metal ion transport GO:0030001 74 0.022
camera type eye morphogenesis GO:0048593 2 0.022
signal transduction by phosphorylation GO:0023014 107 0.022
nucleoside triphosphate catabolic process GO:0009143 108 0.022
morphogenesis of embryonic epithelium GO:0016331 94 0.021
pigmentation GO:0043473 75 0.021
transcription from rna polymerase ii promoter GO:0006366 368 0.021
tube morphogenesis GO:0035239 191 0.021
nucleotide metabolic process GO:0009117 161 0.021
positive regulation of phosphate metabolic process GO:0045937 139 0.021
negative regulation of cellular biosynthetic process GO:0031327 277 0.021
organophosphate metabolic process GO:0019637 195 0.021
response to nutrient levels GO:0031667 114 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.021
regulation of anatomical structure morphogenesis GO:0022603 242 0.021
actin cytoskeleton organization GO:0030036 206 0.021
regulation of programmed cell death GO:0043067 152 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.020
taxis GO:0042330 304 0.020
regulation of intracellular signal transduction GO:1902531 236 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
gtp metabolic process GO:0046039 72 0.020
regulation of localization GO:0032879 275 0.020
nucleoside triphosphate metabolic process GO:0009141 120 0.020
positive regulation of developmental process GO:0051094 143 0.020
cell motility GO:0048870 251 0.020
regulation of cell differentiation GO:0045595 302 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
purine ribonucleotide catabolic process GO:0009154 109 0.019
compound eye morphogenesis GO:0001745 249 0.019
monocarboxylic acid transport GO:0015718 3 0.019
establishment of localization in cell GO:0051649 402 0.019
eye morphogenesis GO:0048592 260 0.019
nucleoside phosphate catabolic process GO:1901292 110 0.019
positive regulation of protein metabolic process GO:0051247 128 0.019
glycosyl compound catabolic process GO:1901658 112 0.019
negative regulation of developmental process GO:0051093 201 0.019
renal tubule development GO:0061326 64 0.019
embryonic development via the syncytial blastoderm GO:0001700 148 0.019
cell cell junction organization GO:0045216 55 0.019
cellular ketone metabolic process GO:0042180 24 0.018
cell adhesion GO:0007155 136 0.018
positive regulation of hydrolase activity GO:0051345 78 0.018
regulation of defense response GO:0031347 102 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
response to light stimulus GO:0009416 124 0.018
response to bacterium GO:0009617 198 0.018
gtp catabolic process GO:0006184 72 0.018
negative regulation of biosynthetic process GO:0009890 277 0.018
ribonucleoside triphosphate metabolic process GO:0009199 119 0.018
digestive tract development GO:0048565 149 0.018
wnt signaling pathway GO:0016055 98 0.018
positive regulation of signal transduction GO:0009967 223 0.018
guanosine containing compound metabolic process GO:1901068 74 0.018
immune system process GO:0002376 347 0.018
positive regulation of phosphorus metabolic process GO:0010562 139 0.018
cellular macromolecule localization GO:0070727 220 0.018
regulation of cellular response to stress GO:0080135 89 0.017
cellular response to dna damage stimulus GO:0006974 223 0.017
regulation of cellular catabolic process GO:0031329 157 0.017
nucleotide catabolic process GO:0009166 109 0.017
response to radiation GO:0009314 155 0.017
phagocytosis GO:0006909 215 0.017
Fly
developmental growth GO:0048589 280 0.017
autophagic cell death GO:0048102 83 0.017
defense response to gram negative bacterium GO:0050829 94 0.017
outflow tract morphogenesis GO:0003151 4 0.017
cell junction organization GO:0034330 57 0.017
single organism intracellular transport GO:1902582 207 0.017
establishment of protein localization GO:0045184 163 0.017
growth GO:0040007 359 0.017
positive regulation of cell motility GO:2000147 3 0.017
organic substance catabolic process GO:1901575 308 0.017
cell proliferation GO:0008283 299 0.017
regulation of mapk cascade GO:0043408 92 0.017
purine nucleotide catabolic process GO:0006195 109 0.017
salivary gland cell autophagic cell death GO:0035071 83 0.017
ras protein signal transduction GO:0007265 88 0.017
sensory organ morphogenesis GO:0090596 260 0.017
signal transduction in response to dna damage GO:0042770 3 0.016
malpighian tubule morphogenesis GO:0007443 44 0.016
localization of cell GO:0051674 257 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
heart development GO:0007507 82 0.016
cation transport GO:0006812 110 0.016
mesenchymal cell development GO:0014031 1 0.016
purine nucleoside metabolic process GO:0042278 127 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
regulation of peptidase activity GO:0052547 39 0.016
regionalization GO:0003002 416 0.016
apoptotic process GO:0006915 159 0.016
ommochrome metabolic process GO:0046152 19 0.016
negative regulation of rna metabolic process GO:0051253 251 0.016
cellular amino acid metabolic process GO:0006520 61 0.016
compound eye development GO:0048749 307 0.016
protein transport GO:0015031 155 0.016
response to hexose GO:0009746 3 0.016
establishment of tissue polarity GO:0007164 87 0.016
antimicrobial humoral response GO:0019730 99 0.016
regulation of transport GO:0051049 181 0.016
urogenital system development GO:0001655 72 0.015
homeostatic process GO:0042592 199 0.015
cellular amine metabolic process GO:0044106 12 0.015
notch signaling pathway GO:0007219 120 0.015
embryonic morphogenesis GO:0048598 206 0.015
positive regulation of catabolic process GO:0009896 105 0.015
regulation of multi organism process GO:0043900 131 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
forebrain development GO:0030900 2 0.015
developmental pigmentation GO:0048066 68 0.015
endocytosis GO:0006897 310 0.015
Fly
stem cell proliferation GO:0072089 88 0.015
transmembrane transport GO:0055085 139 0.015
protein phosphorylation GO:0006468 169 0.015
defense response to bacterium GO:0042742 178 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
regulation of proteolysis GO:0030162 87 0.015
embryonic hindgut morphogenesis GO:0048619 48 0.015
photoreceptor cell differentiation GO:0046530 170 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
mitotic cell cycle phase transition GO:0044772 138 0.015
amine metabolic process GO:0009308 12 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
guanosine containing compound catabolic process GO:1901069 74 0.014
cellular protein localization GO:0034613 160 0.014
actin filament based process GO:0030029 220 0.014
regulation of apoptotic process GO:0042981 130 0.014
erbb signaling pathway GO:0038127 58 0.014
mesenchymal cell differentiation GO:0048762 1 0.014
antimicrobial peptide production GO:0002775 46 0.014
mapk cascade GO:0000165 107 0.014
positive regulation of macromolecule metabolic process GO:0010604 405 0.014
positive regulation of signaling GO:0023056 243 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
organelle fission GO:0048285 340 0.014
multicellular organismal aging GO:0010259 140 0.014
intracellular transport GO:0046907 228 0.014
regulation of immune system process GO:0002682 176 0.014
leg disc morphogenesis GO:0007478 80 0.014
response to glucose GO:0009749 2 0.014
cellular protein modification process GO:0006464 438 0.014
single organism biosynthetic process GO:0044711 206 0.014
cell maturation GO:0048469 144 0.014
cellular amide metabolic process GO:0043603 80 0.014
retina development in camera type eye GO:0060041 4 0.014
regulation of small gtpase mediated signal transduction GO:0051056 93 0.014
regulation of catabolic process GO:0009894 170 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.014
cell recognition GO:0008037 102 0.014
tissue death GO:0016271 102 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
organic acid metabolic process GO:0006082 103 0.014
muscle structure development GO:0061061 224 0.014
macromolecular complex assembly GO:0065003 256 0.014
negative regulation of peptide hormone processing GO:0060570 1 0.014
cell migration GO:0016477 238 0.014
imaginal disc derived leg morphogenesis GO:0007480 80 0.014
regulation of endopeptidase activity GO:0052548 36 0.014
central nervous system development GO:0007417 201 0.014
microtubule organizing center organization GO:0031023 168 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
negative regulation of mitotic cell cycle GO:0045930 109 0.013
wound healing GO:0042060 75 0.013
embryonic organ development GO:0048568 50 0.013
limb morphogenesis GO:0035108 1 0.013
macromolecule catabolic process GO:0009057 161 0.013
spermatogenesis GO:0007283 200 0.013
oxoacid metabolic process GO:0043436 103 0.013
endomembrane system organization GO:0010256 119 0.013
negative regulation of defense response GO:0031348 35 0.013
axon guidance GO:0007411 233 0.013
gland development GO:0048732 191 0.013
segmentation GO:0035282 207 0.013
regulation of response to external stimulus GO:0032101 115 0.013
telencephalon development GO:0021537 2 0.013
centrosome duplication GO:0051298 121 0.013
immune response regulating signaling pathway GO:0002764 2 0.013
organophosphate catabolic process GO:0046434 112 0.013
single organism cellular localization GO:1902580 180 0.013
hindgut morphogenesis GO:0007442 58 0.013
cytoskeleton dependent cytokinesis GO:0061640 81 0.013
renal system development GO:0072001 72 0.013
positive regulation of cell death GO:0010942 69 0.013
regulation of gene expression epigenetic GO:0040029 128 0.013
negative regulation of rna biosynthetic process GO:1902679 240 0.013
epidermal growth factor receptor signaling pathway GO:0007173 58 0.013
regulation of cell development GO:0060284 215 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
regulation of antimicrobial peptide production GO:0002784 44 0.012
embryonic pattern specification GO:0009880 174 0.012
head development GO:0060322 135 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
extracellular structure organization GO:0043062 46 0.012
sterol homeostasis GO:0055092 4 0.012
regulation of organelle organization GO:0033043 196 0.012
response to nitrogen compound GO:1901698 90 0.012
intracellular protein transport GO:0006886 104 0.012
dna damage checkpoint GO:0000077 78 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
synapse organization GO:0050808 196 0.012
eye development GO:0001654 323 0.012
embryo development ending in birth or egg hatching GO:0009792 152 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
immune response activating signal transduction GO:0002757 2 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
dorsal closure GO:0007391 79 0.012
response to monosaccharide GO:0034284 4 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
dna integrity checkpoint GO:0031570 81 0.012
regulation of response to biotic stimulus GO:0002831 63 0.012
positive regulation of cell migration GO:0030335 2 0.012
activation of innate immune response GO:0002218 4 0.012
mitotic nuclear division GO:0007067 213 0.012
regulation of cell proliferation GO:0042127 163 0.012
regulation of cell cycle process GO:0010564 181 0.012
cholesterol homeostasis GO:0042632 3 0.012
histolysis GO:0007559 102 0.012
response to oxygen containing compound GO:1901700 200 0.012
positive regulation of transport GO:0051050 92 0.012
muscle tissue morphogenesis GO:0060415 2 0.012
peptide hormone processing GO:0016486 2 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
ommochrome biosynthetic process GO:0006727 19 0.011
positive regulation of gene expression GO:0010628 290 0.011
regulation of organ morphogenesis GO:2000027 78 0.011
regulation of cellular localization GO:0060341 136 0.011
renal tubule morphogenesis GO:0061333 44 0.011
spindle organization GO:0007051 253 0.011
cytoplasmic transport GO:0016482 130 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
regulation of cellular amide metabolic process GO:0034248 39 0.011
cation transmembrane transport GO:0098655 88 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
positive regulation of immune response GO:0050778 63 0.011
regulation of neurogenesis GO:0050767 158 0.011
digestive tract morphogenesis GO:0048546 127 0.011
biological adhesion GO:0022610 138 0.011
single organism behavior GO:0044708 391 0.011
cellular homeostasis GO:0019725 80 0.011
cardiocyte differentiation GO:0035051 29 0.011
secondary metabolic process GO:0019748 75 0.011
developmental maturation GO:0021700 172 0.011
chromosome segregation GO:0007059 157 0.011
dendrite morphogenesis GO:0048813 199 0.011
dendrite development GO:0016358 204 0.011
anatomical structure homeostasis GO:0060249 97 0.011
positive regulation of biosynthetic process GO:0009891 316 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
regulation of jnk cascade GO:0046328 40 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
secretion GO:0046903 109 0.010
gastrulation involving germ band extension GO:0010004 36 0.010
negative regulation of immune system process GO:0002683 50 0.010
rho protein signal transduction GO:0007266 14 0.010
endoderm formation GO:0001706 3 0.010
positive regulation of apoptotic signaling pathway GO:2001235 4 0.010
centrosome organization GO:0051297 163 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
nephron development GO:0072006 3 0.010
negative regulation of transcription dna templated GO:0045892 237 0.010
cellular response to abiotic stimulus GO:0071214 58 0.010
regulation of epithelial cell proliferation GO:0050678 4 0.010
muscle organ development GO:0007517 127 0.010
ovarian follicle cell development GO:0030707 248 0.010
chemical homeostasis GO:0048878 92 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.010
cellular ion homeostasis GO:0006873 39 0.010
centrosome cycle GO:0007098 137 0.010
ameboidal type cell migration GO:0001667 151 0.010
regulation of developmental pigmentation GO:0048070 24 0.010
response to organophosphorus GO:0046683 2 0.010
regulation of immune response GO:0050776 118 0.010
positive regulation of programmed cell death GO:0043068 62 0.010
response to lipopolysaccharide GO:0032496 4 0.010
cell fate determination involved in pattern specification GO:0060582 19 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
response to organic cyclic compound GO:0014070 89 0.010
regulation of cell substrate adhesion GO:0010810 2 0.010
mitotic dna integrity checkpoint GO:0044774 75 0.010
regulation of cell cycle phase transition GO:1901987 130 0.010
jnk cascade GO:0007254 50 0.010
rna processing GO:0006396 147 0.010

Mec2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.017
musculoskeletal system disease DOID:17 0 0.016
urinary system disease DOID:18 0 0.012
cardiovascular system disease DOID:1287 0 0.011
sensory system disease DOID:0050155 0 0.011