Drosophila melanogaster

41 known processes

Thiolase (Dmel_CG4581)

CG4581 gene product from transcript CG4581-RA

(Aliases: CG4581,thiolase,Dmel\CG4581)

Thiolase biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
fatty acid beta oxidation GO:0006635 6 0.996
lipid catabolic process GO:0016042 21 0.964
fatty acid oxidation GO:0019395 6 0.927
lipid modification GO:0030258 24 0.903
fatty acid catabolic process GO:0009062 9 0.873
lipid metabolic process GO:0006629 121 0.862
cellular lipid catabolic process GO:0044242 16 0.844
carboxylic acid catabolic process GO:0046395 16 0.755
regulation of lipid storage GO:0010883 22 0.660
organic acid catabolic process GO:0016054 16 0.564
oxoacid metabolic process GO:0043436 103 0.458
monocarboxylic acid metabolic process GO:0032787 29 0.448
lipid oxidation GO:0034440 7 0.418
organic acid metabolic process GO:0006082 103 0.415
carboxylic acid metabolic process GO:0019752 92 0.366
single organism catabolic process GO:0044712 228 0.329
acyl coa metabolic process GO:0006637 3 0.324
acylglycerol catabolic process GO:0046464 3 0.322
cellular lipid metabolic process GO:0044255 83 0.312
oxidation reduction process GO:0055114 123 0.296
monocarboxylic acid catabolic process GO:0072329 10 0.287
catabolic process GO:0009056 409 0.274
lipid storage GO:0019915 38 0.266
response to extracellular stimulus GO:0009991 116 0.227
positive regulation of lipid metabolic process GO:0045834 4 0.202
generation of precursor metabolites and energy GO:0006091 42 0.199
lipid localization GO:0010876 54 0.168
polysaccharide metabolic process GO:0005976 11 0.142
small molecule metabolic process GO:0044281 305 0.126
response to nutrient levels GO:0031667 114 0.119
fatty acid metabolic process GO:0006631 20 0.117
organic substance catabolic process GO:1901575 308 0.113
small molecule catabolic process GO:0044282 21 0.107
maintenance of location GO:0051235 73 0.099
aging GO:0007568 143 0.093
thioester metabolic process GO:0035383 3 0.091
response to starvation GO:0042594 97 0.088
cellular ketone metabolic process GO:0042180 24 0.084
cellular polysaccharide biosynthetic process GO:0033692 7 0.075
triglyceride metabolic process GO:0006641 12 0.073
cellular catabolic process GO:0044248 372 0.066
response to endogenous stimulus GO:0009719 119 0.065
response to water deprivation GO:0009414 4 0.065
determination of adult lifespan GO:0008340 137 0.061
single organism biosynthetic process GO:0044711 206 0.056
cellular response to chemical stimulus GO:0070887 199 0.054
cellular cation homeostasis GO:0030003 38 0.051
g protein coupled receptor signaling pathway GO:0007186 136 0.050
telencephalon development GO:0021537 2 0.050
glucan biosynthetic process GO:0009250 2 0.048
lipid biosynthetic process GO:0008610 46 0.048
sulfur compound metabolic process GO:0006790 59 0.046
polysaccharide biosynthetic process GO:0000271 7 0.045
death GO:0016265 284 0.044
imaginal disc derived wing morphogenesis GO:0007476 337 0.043
cholesterol homeostasis GO:0042632 3 0.041
single organism carbohydrate metabolic process GO:0044723 72 0.041
single organism intracellular transport GO:1902582 207 0.041
wound healing GO:0042060 75 0.039
cellular aldehyde metabolic process GO:0006081 10 0.039
regulation of lipid metabolic process GO:0019216 15 0.038
calcium ion homeostasis GO:0055074 23 0.038
tube development GO:0035295 244 0.038
lipid particle organization GO:0034389 7 0.038
lateral inhibition GO:0046331 206 0.038
energy derivation by oxidation of organic compounds GO:0015980 32 0.038
regulation of localization GO:0032879 275 0.038
organelle assembly GO:0070925 198 0.037
tube morphogenesis GO:0035239 191 0.035
iron ion homeostasis GO:0055072 5 0.035
wing disc morphogenesis GO:0007472 344 0.034
negative regulation of response to stimulus GO:0048585 258 0.034
multicellular organismal aging GO:0010259 140 0.034
intracellular transport GO:0046907 228 0.032
negative regulation of signal transduction GO:0009968 206 0.032
organic hydroxy compound metabolic process GO:1901615 83 0.032
negative regulation of cell death GO:0060548 81 0.032
open tracheal system development GO:0007424 204 0.031
imaginal disc derived appendage development GO:0048737 399 0.031
transcription from rna polymerase ii promoter GO:0006366 368 0.030
protein complex biogenesis GO:0070271 201 0.030
organic substance transport GO:0071702 257 0.030
homeostatic process GO:0042592 199 0.029
negative regulation of cellular metabolic process GO:0031324 382 0.029
negative regulation of signaling GO:0023057 219 0.028
regulation of cellular ketone metabolic process GO:0010565 3 0.028
chemical homeostasis GO:0048878 92 0.028
organonitrogen compound metabolic process GO:1901564 318 0.027
negative regulation of biosynthetic process GO:0009890 277 0.027
vitamin metabolic process GO:0006766 2 0.027
carbohydrate biosynthetic process GO:0016051 17 0.027
imaginal disc derived appendage morphogenesis GO:0035114 395 0.026
response to organonitrogen compound GO:0010243 75 0.026
regulation of cellular localization GO:0060341 136 0.026
appendage development GO:0048736 401 0.026
response to hormone GO:0009725 45 0.025
mitochondrion organization GO:0007005 65 0.025
neutral lipid metabolic process GO:0006638 12 0.025
acylglycerol biosynthetic process GO:0046463 2 0.025
negative regulation of cell communication GO:0010648 223 0.025
epithelial cell differentiation GO:0030855 322 0.024
post embryonic appendage morphogenesis GO:0035120 385 0.024
response to lipopolysaccharide GO:0032496 4 0.024
detection of stimulus GO:0051606 156 0.024
body morphogenesis GO:0010171 2 0.023
response to peptide hormone GO:0043434 29 0.022
programmed cell death GO:0012501 257 0.022
gland development GO:0048732 191 0.022
appendage morphogenesis GO:0035107 397 0.021
macromolecular complex assembly GO:0065003 256 0.021
gastrulation GO:0007369 70 0.021
protein complex assembly GO:0006461 200 0.021
response to abiotic stimulus GO:0009628 341 0.021
small molecule biosynthetic process GO:0044283 37 0.021
response to desiccation GO:0009269 3 0.021
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
cell death GO:0008219 279 0.020
response to organic substance GO:0010033 284 0.020
cellular response to peptide GO:1901653 28 0.020
triglyceride biosynthetic process GO:0019432 2 0.020
response to copper ion GO:0046688 4 0.020
cell cell signaling involved in cell fate commitment GO:0045168 210 0.019
acylglycerol metabolic process GO:0006639 12 0.019
establishment of localization in cell GO:0051649 402 0.019
salivary gland cell autophagic cell death GO:0035071 83 0.019
regulation of cell proliferation GO:0042127 163 0.019
protein modification process GO:0036211 438 0.019
response to alcohol GO:0097305 95 0.019
larval development GO:0002164 104 0.018
positive regulation of cell motility GO:2000147 3 0.018
positive regulation of signaling GO:0023056 243 0.018
regulation of catabolic process GO:0009894 170 0.017
regulation of multicellular organismal development GO:2000026 414 0.017
cell aging GO:0007569 2 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.017
response to biotic stimulus GO:0009607 294 0.017
response to inorganic substance GO:0010035 44 0.017
regulation of molecular function GO:0065009 217 0.017
negative regulation of cellular component organization GO:0051129 108 0.016
pyridine nucleotide metabolic process GO:0019362 2 0.016
glycerolipid metabolic process GO:0046486 34 0.016
morphogenesis of follicular epithelium GO:0016333 36 0.016
organic anion transport GO:0015711 28 0.016
regulation of sequestering of triglyceride GO:0010889 3 0.016
regulation of mitochondrion organization GO:0010821 12 0.016
response to radiation GO:0009314 155 0.015
carbohydrate metabolic process GO:0005975 82 0.015
medium chain fatty acid metabolic process GO:0051791 1 0.015
connective tissue development GO:0061448 3 0.015
positive regulation of cell communication GO:0010647 250 0.015
regulation of cell differentiation GO:0045595 302 0.014
regulation of organelle organization GO:0033043 196 0.014
striated muscle cell differentiation GO:0051146 90 0.014
apoptotic process GO:0006915 159 0.014
pigment biosynthetic process GO:0046148 36 0.014
positive regulation of cell migration GO:0030335 2 0.014
positive regulation of catabolic process GO:0009896 105 0.014
response to nitrogen compound GO:1901698 90 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
response to oxygen containing compound GO:1901700 200 0.014
muscle structure development GO:0061061 224 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
negative regulation of programmed cell death GO:0043069 72 0.014
regulation of lipid biosynthetic process GO:0046890 6 0.014
respiratory system development GO:0060541 213 0.013
cellular modified amino acid metabolic process GO:0006575 45 0.013
camera type eye development GO:0043010 4 0.013
glucosamine containing compound catabolic process GO:1901072 3 0.013
cellular glucan metabolic process GO:0006073 6 0.013
acetaldehyde metabolic process GO:0006117 5 0.013
single organism behavior GO:0044708 391 0.013
response to ethanol GO:0045471 59 0.013
regulation of glycogen metabolic process GO:0070873 3 0.013
neutral lipid biosynthetic process GO:0046460 2 0.013
acylglycerol homeostasis GO:0055090 19 0.012
regulation of proteolysis GO:0030162 87 0.012
positive regulation of response to stimulus GO:0048584 323 0.012
anion transport GO:0006820 41 0.012
cellular response to organic substance GO:0071310 132 0.012
regulation of cell death GO:0010941 173 0.012
response to peptide GO:1901652 29 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.012
regulation of apoptotic process GO:0042981 130 0.012
immune system process GO:0002376 347 0.012
circulatory system development GO:0072359 82 0.012
protein localization GO:0008104 284 0.012
single organism membrane organization GO:0044802 93 0.012
purine nucleoside monophosphate metabolic process GO:0009126 50 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
positive regulation of lipid storage GO:0010884 4 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
response to light stimulus GO:0009416 124 0.011
establishment of protein localization GO:0045184 163 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
age dependent general metabolic decline GO:0007571 3 0.011
positive regulation of apoptotic signaling pathway GO:2001235 4 0.011
response to lipid GO:0033993 38 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
androgen metabolic process GO:0008209 1 0.011
membrane biogenesis GO:0044091 8 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
cellular protein modification process GO:0006464 438 0.011
striated muscle myosin thick filament assembly GO:0071688 3 0.011
apoptotic signaling pathway GO:0097190 27 0.011
positive regulation of biosynthetic process GO:0009891 316 0.010
cytoplasmic transport GO:0016482 130 0.010
cardiac muscle cell differentiation GO:0055007 4 0.010
negative regulation of gene expression GO:0010629 387 0.010
cellular polysaccharide metabolic process GO:0044264 11 0.010
fat soluble vitamin metabolic process GO:0006775 1 0.010
response to wounding GO:0009611 94 0.010
female sex differentiation GO:0046660 20 0.010
mitotic spindle organization GO:0007052 220 0.010
membrane organization GO:0061024 112 0.010
regulation of lipid catabolic process GO:0050994 3 0.010
phagocytosis GO:0006909 215 0.010

Thiolase disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.077
inherited metabolic disorder DOID:655 0 0.077
disease of anatomical entity DOID:7 0 0.026