Drosophila melanogaster

211 known processes

E(bx) (Dmel_CG32346)

Enhancer of bithorax

(Aliases: Dmel\CG32346,CG10894,NURF,l(3)122,Nurf-215,dNURF301,CG7022,NURF-301,NURF215,l(3)ry122,Nurf301,NURF301,p215,CG32478,NuRF301,CG32346,nurf301,CG17135,dNURF,NURF-215,En-bx,E(Bx),p301)

E(bx) biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 0.699
nucleosome mobilization GO:0042766 9 0.681
regulation of cell development GO:0060284 215 0.644
post embryonic appendage morphogenesis GO:0035120 385 0.553
dna conformation change GO:0071103 105 0.528
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.502
imaginal disc derived appendage morphogenesis GO:0035114 395 0.485
nucleobase containing compound catabolic process GO:0034655 165 0.473
Human
semaphorin plexin signaling pathway involved in regulation of photoreceptor cell axon guidance GO:2000305 2 0.421
regulation of multicellular organismal development GO:2000026 414 0.417
Worm
regulation of intracellular signal transduction GO:1902531 236 0.389
appendage development GO:0048736 401 0.375
wing disc morphogenesis GO:0007472 344 0.356
positive regulation of cellular biosynthetic process GO:0031328 316 0.349
Human Worm
regulation of phosphate metabolic process GO:0019220 210 0.322
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.320
Human Worm
imaginal disc derived wing morphogenesis GO:0007476 337 0.314
meiotic cell cycle process GO:1903046 132 0.287
positive regulation of transcription dna templated GO:0045893 266 0.286
Human Worm
purine containing compound catabolic process GO:0072523 112 0.276
Human
regulation of organelle organization GO:0033043 196 0.265
positive regulation of rna metabolic process GO:0051254 271 0.259
Human Worm
appendage morphogenesis GO:0035107 397 0.252
ras protein signal transduction GO:0007265 88 0.224
imaginal disc derived appendage development GO:0048737 399 0.211
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.207
Human Worm
organic substance catabolic process GO:1901575 308 0.206
Human
hematopoietic or lymphoid organ development GO:0048534 57 0.203
transcription from rna polymerase ii promoter GO:0006366 368 0.203
regulation of mitotic cell cycle GO:0007346 190 0.195
positive regulation of nucleic acid templated transcription GO:1903508 266 0.193
Human Worm
meiotic chromosome segregation GO:0045132 59 0.191
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.182
Human Worm
regionalization GO:0003002 416 0.176
Mouse
protein modification by small protein conjugation or removal GO:0070647 106 0.161
embryo development ending in birth or egg hatching GO:0009792 152 0.159
Mouse
positive regulation of response to stimulus GO:0048584 323 0.158
regulation of neurogenesis GO:0050767 158 0.155
heterochromatin organization GO:0070828 25 0.154
dendrite development GO:0016358 204 0.153
regulation of cell differentiation GO:0045595 302 0.153
organelle fission GO:0048285 340 0.152
dna packaging GO:0006323 91 0.149
chromatin assembly GO:0031497 48 0.149
compound eye morphogenesis GO:0001745 249 0.143
dna endoreduplication GO:0042023 22 0.139
morphogenesis of an epithelium GO:0002009 276 0.137
cellular response to dna damage stimulus GO:0006974 223 0.132
aromatic compound catabolic process GO:0019439 166 0.129
Human
immune system process GO:0002376 347 0.128
chromatin modification GO:0016568 147 0.128
chromatin remodeling GO:0006338 72 0.125
sensory neuron axon guidance GO:0097374 2 0.122
regulation of small gtpase mediated signal transduction GO:0051056 93 0.121
positive regulation of macromolecule metabolic process GO:0010604 405 0.116
Human Worm
response to sterol GO:0036314 34 0.111
small gtpase mediated signal transduction GO:0007264 88 0.110
dendrite morphogenesis GO:0048813 199 0.110
mitotic cell cycle phase transition GO:0044772 138 0.103
regulation of photoreceptor cell differentiation GO:0046532 34 0.101
regulation of dendrite morphogenesis GO:0048814 28 0.097
nucleosome organization GO:0034728 59 0.095
organic cyclic compound catabolic process GO:1901361 168 0.093
Human
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.091
Worm
chromatin organization GO:0006325 207 0.091
mitotic dna damage checkpoint GO:0044773 74 0.090
meiotic cell cycle GO:0051321 171 0.086
small molecule metabolic process GO:0044281 305 0.085
Human
cell death GO:0008219 279 0.084
cellular protein modification process GO:0006464 438 0.083
response to alcohol GO:0097305 95 0.079
positive regulation of phosphate metabolic process GO:0045937 139 0.078
nucleobase containing small molecule metabolic process GO:0055086 174 0.077
Human
regulation of neuron differentiation GO:0045664 103 0.076
nucleoside phosphate metabolic process GO:0006753 162 0.076
Human
positive regulation of proteolysis GO:0045862 52 0.075
positive regulation of cell development GO:0010720 61 0.075
regulation of cell death GO:0010941 173 0.074
death GO:0016265 284 0.074
axon development GO:0061564 297 0.073
chromosome condensation GO:0030261 41 0.073
blastoderm segmentation GO:0007350 159 0.072
cell cycle phase transition GO:0044770 140 0.072
embryonic development via the syncytial blastoderm GO:0001700 148 0.071
dna metabolic process GO:0006259 227 0.070
negative regulation of developmental process GO:0051093 201 0.068
Worm
organonitrogen compound metabolic process GO:1901564 318 0.067
Human
collateral sprouting GO:0048668 3 0.066
regulation of cellular response to stress GO:0080135 89 0.066
purine nucleoside catabolic process GO:0006152 112 0.065
Human
dna integrity checkpoint GO:0031570 81 0.064
semaphorin plexin signaling pathway GO:0071526 4 0.063
regulation of sister chromatid cohesion GO:0007063 2 0.062
positive regulation of cell communication GO:0010647 250 0.062
single organism catabolic process GO:0044712 228 0.061
Human
tube morphogenesis GO:0035239 191 0.061
regulation of neuron projection development GO:0010975 69 0.057
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.057
Human
purine nucleoside triphosphate catabolic process GO:0009146 108 0.057
Human
morphogenesis of embryonic epithelium GO:0016331 94 0.057
developmental maturation GO:0021700 172 0.055
positive regulation of developmental process GO:0051094 143 0.055
regulation of cell cycle GO:0051726 291 0.055
regulation of hydrolase activity GO:0051336 97 0.055
heterocycle catabolic process GO:0046700 166 0.053
Human
male meiosis chromosome segregation GO:0007060 10 0.052
regulation of anatomical structure morphogenesis GO:0022603 242 0.051
cellular nitrogen compound catabolic process GO:0044270 165 0.051
Human
chromatin assembly or disassembly GO:0006333 52 0.051
cell cycle checkpoint GO:0000075 95 0.051
histone methylation GO:0016571 40 0.050
mitotic spindle organization GO:0007052 220 0.050
regulation of response to external stimulus GO:0032101 115 0.049
locomotory behavior GO:0007626 176 0.049
apoptotic process GO:0006915 159 0.049
nucleoside triphosphate catabolic process GO:0009143 108 0.047
Human
intracellular signal transduction GO:0035556 300 0.047
ribonucleoside monophosphate catabolic process GO:0009158 39 0.046
Human
nuclear division GO:0000280 332 0.045
male gamete generation GO:0048232 201 0.045
negative regulation of cellular metabolic process GO:0031324 382 0.044
Human
nucleoside phosphate catabolic process GO:1901292 110 0.044
Human
regulation of axon extension involved in axon guidance GO:0048841 4 0.043
photoreceptor cell development GO:0042461 96 0.043
immune response GO:0006955 246 0.042
negative regulation of signal transduction GO:0009968 206 0.042
organophosphate catabolic process GO:0046434 112 0.042
Human
immune system development GO:0002520 57 0.042
catabolic process GO:0009056 409 0.041
Human
positive regulation of neurogenesis GO:0050769 41 0.041
regulation of response to stress GO:0080134 200 0.041
response to ecdysone GO:0035075 34 0.041
eye antennal disc development GO:0035214 60 0.041
humoral immune response GO:0006959 117 0.041
body morphogenesis GO:0010171 2 0.041
eye morphogenesis GO:0048592 260 0.040
glycosyl compound metabolic process GO:1901657 127 0.040
Human
positive regulation of multicellular organismal process GO:0051240 143 0.040
induction of programmed cell death GO:0012502 12 0.039
regulation of gtp catabolic process GO:0033124 44 0.039
regulation of cellular component biogenesis GO:0044087 201 0.038
phosphorylation GO:0016310 294 0.038
chromosome segregation GO:0007059 157 0.038
nucleotide metabolic process GO:0009117 161 0.037
Human
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.037
Human
positive regulation of rna biosynthetic process GO:1902680 266 0.037
Human Worm
histone lysine methylation GO:0034968 32 0.037
positive regulation of signaling GO:0023056 243 0.036
tissue morphogenesis GO:0048729 297 0.036
purine nucleoside triphosphate metabolic process GO:0009144 119 0.036
Human
adult behavior GO:0030534 137 0.036
regulation of cytoskeleton organization GO:0051493 89 0.036
cell recognition GO:0008037 102 0.035
purine ribonucleoside metabolic process GO:0046128 127 0.035
Human
gland development GO:0048732 191 0.035
compound eye photoreceptor development GO:0042051 78 0.035
programmed cell death GO:0012501 257 0.034
rhythmic process GO:0048511 106 0.034
negative regulation of apoptotic process GO:0043066 63 0.033
spermatogenesis GO:0007283 200 0.033
atp dependent chromatin remodeling GO:0043044 22 0.032
digestive tract development GO:0048565 149 0.032
negative regulation of gene expression GO:0010629 387 0.032
Human
positive regulation of nf kappab import into nucleus GO:0042346 1 0.032
purine ribonucleotide metabolic process GO:0009150 145 0.031
Human
glycosyl compound catabolic process GO:1901658 112 0.031
Human
ribonucleoside metabolic process GO:0009119 127 0.031
Human
negative regulation of gene expression epigenetic GO:0045814 77 0.031
regulation of catalytic activity GO:0050790 185 0.031
macromolecule catabolic process GO:0009057 161 0.030
circadian rhythm GO:0007623 105 0.030
positive regulation of signal transduction GO:0009967 223 0.029
regulation of immune response GO:0050776 118 0.029
tube development GO:0035295 244 0.029
chromatin silencing GO:0006342 76 0.029
positive regulation of nervous system development GO:0051962 69 0.029
ribose phosphate metabolic process GO:0019693 145 0.028
Human
purine containing compound metabolic process GO:0072521 155 0.028
Human
axon target recognition GO:0007412 16 0.028
negative regulation of signaling GO:0023057 219 0.028
cell cycle dna replication GO:0044786 23 0.028
digestive system development GO:0055123 149 0.028
negative regulation of cellular biosynthetic process GO:0031327 277 0.028
Human
positive regulation of biosynthetic process GO:0009891 316 0.027
Human Worm
positive regulation of neuron differentiation GO:0045666 26 0.027
nucleoside triphosphate metabolic process GO:0009141 120 0.026
Human
positive regulation of phosphorus metabolic process GO:0010562 139 0.026
positive regulation of gene expression GO:0010628 290 0.026
Human Worm
regulation of mitotic cell cycle phase transition GO:1901990 130 0.026
carbohydrate metabolic process GO:0005975 82 0.026
positive regulation of cellular catabolic process GO:0031331 95 0.026
regulation of programmed cell death GO:0043067 152 0.026
rna localization GO:0006403 115 0.025
hemopoiesis GO:0030097 46 0.025
ribonucleoside triphosphate catabolic process GO:0009203 108 0.025
Human
regulation of cell cycle phase transition GO:1901987 130 0.025
purine nucleoside metabolic process GO:0042278 127 0.025
Human
tripartite regional subdivision GO:0007351 103 0.025
organonitrogen compound catabolic process GO:1901565 128 0.025
Human
larval development GO:0002164 104 0.025
Worm
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
axonogenesis GO:0007409 290 0.025
positive regulation of endopeptidase activity GO:0010950 26 0.024
regulation of ras protein signal transduction GO:0046578 93 0.024
macromolecular complex assembly GO:0065003 256 0.024
oocyte differentiation GO:0009994 145 0.024
regulation of organ morphogenesis GO:2000027 78 0.024
protein localization GO:0008104 284 0.024
photoreceptor cell differentiation GO:0046530 170 0.024
histone h3 k4 methylation GO:0051568 16 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.023
Human
gene silencing by rna GO:0031047 57 0.023
regulation of circadian rhythm GO:0042752 49 0.023
neuron recognition GO:0008038 101 0.023
digestive tract morphogenesis GO:0048546 127 0.023
gene silencing GO:0016458 138 0.022
peptidyl lysine methylation GO:0018022 16 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.022
Human
stress activated protein kinase signaling cascade GO:0031098 55 0.022
regulation of glial cell differentiation GO:0045685 1 0.022
regulation of photoreceptor cell axon guidance GO:2000289 5 0.022
substrate dependent cell migration GO:0006929 3 0.021
covalent chromatin modification GO:0016569 106 0.021
regulation of cellular localization GO:0060341 136 0.021
embryonic hemopoiesis GO:0035162 26 0.021
protein modification by small protein conjugation GO:0032446 79 0.021
negative regulation of cell death GO:0060548 81 0.021
purine ribonucleoside catabolic process GO:0046130 112 0.021
Human
negative regulation of cell differentiation GO:0045596 143 0.021
carbohydrate derivative catabolic process GO:1901136 118 0.021
Human
dna dependent dna replication GO:0006261 17 0.021
ribonucleotide catabolic process GO:0009261 109 0.021
Human
homeostatic process GO:0042592 199 0.020
enzyme linked receptor protein signaling pathway GO:0007167 179 0.020
axon guidance GO:0007411 233 0.020
dna replication GO:0006260 48 0.020
embryonic pattern specification GO:0009880 174 0.020
meiosis i GO:0007127 59 0.020
positive regulation of cell differentiation GO:0045597 64 0.019
dna damage checkpoint GO:0000077 78 0.019
regulation of chromosome organization GO:0033044 64 0.019
chromosome separation GO:0051304 42 0.019
regulation of gene expression epigenetic GO:0040029 128 0.019
regulation of catabolic process GO:0009894 170 0.019
negative regulation of molecular function GO:0044092 51 0.019
imaginal disc growth GO:0007446 37 0.019
nucleoside monophosphate catabolic process GO:0009125 39 0.018
Human
atp catabolic process GO:0006200 38 0.018
Human
dephosphorylation GO:0016311 51 0.018
regulation of embryonic development GO:0045995 68 0.018
regulation of nervous system development GO:0051960 248 0.018
positive regulation of molecular function GO:0044093 136 0.018
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.018
developmental programmed cell death GO:0010623 138 0.017
retina morphogenesis in camera type eye GO:0060042 2 0.017
ribonucleotide metabolic process GO:0009259 145 0.017
Human
cellular response to oxygen containing compound GO:1901701 79 0.017
regulation of cellular catabolic process GO:0031329 157 0.017
regulation of apoptotic process GO:0042981 130 0.017
compound eye photoreceptor cell differentiation GO:0001751 140 0.017
negative regulation of cell cycle process GO:0010948 109 0.017
tissue death GO:0016271 102 0.017
positive regulation of intracellular signal transduction GO:1902533 116 0.017
synapse assembly GO:0007416 143 0.016
eye development GO:0001654 323 0.016
regulation of nucleocytoplasmic transport GO:0046822 35 0.016
regulation of proteolysis GO:0030162 87 0.016
salivary gland morphogenesis GO:0007435 145 0.016
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.016
positive regulation of apoptotic process GO:0043065 47 0.016
regulation of axon guidance GO:1902667 10 0.016
compound eye development GO:0048749 307 0.015
cellular macromolecule catabolic process GO:0044265 136 0.015
negative regulation of cell development GO:0010721 62 0.015
regulation of dendrite development GO:0050773 37 0.015
anterior posterior pattern specification GO:0009952 136 0.015
Mouse
regulation of nf kappab import into nucleus GO:0042345 1 0.015
meiotic nuclear division GO:0007126 151 0.015
gland morphogenesis GO:0022612 145 0.015
regulation of nurse cell apoptotic process GO:0045477 9 0.015
organophosphate metabolic process GO:0019637 195 0.015
Human
purine nucleoside monophosphate catabolic process GO:0009128 38 0.014
Human
positive regulation of dendrite morphogenesis GO:0050775 9 0.014
connective tissue development GO:0061448 3 0.014
protein ubiquitination GO:0016567 70 0.014
spindle organization GO:0007051 253 0.014
muscle structure development GO:0061061 224 0.014
purine ribonucleotide catabolic process GO:0009154 109 0.014
Human
dorsal closure GO:0007391 79 0.014
intracellular mrna localization GO:0008298 66 0.014
centrosome organization GO:0051297 163 0.014
camera type eye development GO:0043010 4 0.014
single organism membrane organization GO:0044802 93 0.013
positive regulation of organelle organization GO:0010638 65 0.013
regulation of hemocyte differentiation GO:0045610 22 0.013
g1 s transition of mitotic cell cycle GO:0000082 31 0.013
histone modification GO:0016570 106 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
Human
intracellular protein transport GO:0006886 104 0.013
regulation of molecular function GO:0065009 217 0.013
regulation of chromatin assembly GO:0010847 9 0.013
regulation of striated muscle contraction GO:0006942 2 0.013
larval lymph gland hemocyte differentiation GO:0035168 11 0.013
protein complex assembly GO:0006461 200 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.012
Human
regulation of reproductive process GO:2000241 54 0.012
induction of programmed cell death by ecdysone GO:0035078 12 0.012
positive regulation of programmed cell death GO:0043068 62 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
Human
nucleocytoplasmic transport GO:0006913 72 0.012
phagocytosis GO:0006909 215 0.012
macromolecule methylation GO:0043414 45 0.012
nucleoside catabolic process GO:0009164 112 0.012
Human
histone h4 k20 methylation GO:0034770 4 0.012
smoothened signaling pathway GO:0007224 49 0.012
lamellocyte differentiation GO:0035171 9 0.012
heterochromatin organization involved in chromatin silencing GO:0070868 9 0.012
histone exchange GO:0043486 21 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
maintenance of location GO:0051235 73 0.012
regulation of protein localization GO:0032880 76 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
purine nucleoside monophosphate metabolic process GO:0009126 50 0.011
Human
cellular response to extracellular stimulus GO:0031668 64 0.011
cell cycle g1 s phase transition GO:0044843 31 0.011
cellular protein complex assembly GO:0043623 71 0.011
positive regulation of neuron projection development GO:0010976 14 0.011
mitotic dna integrity checkpoint GO:0044774 75 0.011
negative regulation of programmed cell death GO:0043069 72 0.011
rho protein signal transduction GO:0007266 14 0.011
limb development GO:0060173 1 0.011
proteolysis GO:0006508 192 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
regulation of erk1 and erk2 cascade GO:0070372 39 0.011
nucleoside monophosphate metabolic process GO:0009123 52 0.011
Human
negative regulation of response to stimulus GO:0048585 258 0.011
inter male aggressive behavior GO:0002121 60 0.011
autophagic cell death GO:0048102 83 0.011
exocrine system development GO:0035272 162 0.011
regulation of cellular component size GO:0032535 98 0.011
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.011
purine nucleotide catabolic process GO:0006195 109 0.010
Human
positive regulation of phosphorylation GO:0042327 87 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.010
cellular response to peptide GO:1901653 28 0.010
positive regulation of nucleotide catabolic process GO:0030813 46 0.010
neuron maturation GO:0042551 31 0.010
cellular catabolic process GO:0044248 372 0.010
Human
regulation of purine nucleotide metabolic process GO:1900542 62 0.010

E(bx) disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org