Drosophila melanogaster

56 known processes

slim (Dmel_CG5186)

scruin like at the midline

(Aliases: l(2)s1866,CG5186,Dmel\CG5186)

slim biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cuticle pigmentation GO:0048079 16 0.303
adult chitin containing cuticle pigmentation GO:0048085 16 0.116
vesicle mediated transport GO:0016192 381 0.103
cellular catabolic process GO:0044248 372 0.098
intracellular signal transduction GO:0035556 300 0.092
imaginal disc derived appendage development GO:0048737 399 0.091
organic substance catabolic process GO:1901575 308 0.088
regulation of multicellular organismal development GO:2000026 414 0.088
post embryonic appendage morphogenesis GO:0035120 385 0.084
heterocycle catabolic process GO:0046700 166 0.076
positive regulation of nucleic acid templated transcription GO:1903508 266 0.075
appendage morphogenesis GO:0035107 397 0.074
morphogenesis of an epithelium GO:0002009 276 0.069
imaginal disc derived appendage morphogenesis GO:0035114 395 0.068
endocytosis GO:0006897 310 0.066
localization of cell GO:0051674 257 0.062
regulation of molecular function GO:0065009 217 0.062
positive regulation of rna metabolic process GO:0051254 271 0.061
wing disc morphogenesis GO:0007472 344 0.061
response to organic substance GO:0010033 284 0.060
transcription from rna polymerase ii promoter GO:0006366 368 0.053
tissue morphogenesis GO:0048729 297 0.053
response to oxygen containing compound GO:1901700 200 0.053
molting cycle chitin based cuticle GO:0007591 56 0.052
proteolysis GO:0006508 192 0.052
regulation of developmental pigmentation GO:0048070 24 0.052
chitin based cuticle sclerotization GO:0007593 19 0.049
positive regulation of gene expression GO:0010628 290 0.048
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.048
nucleobase containing compound catabolic process GO:0034655 165 0.047
positive regulation of cell communication GO:0010647 250 0.047
homeostatic process GO:0042592 199 0.046
positive regulation of proteolysis GO:0045862 52 0.045
regulation of adult chitin containing cuticle pigmentation GO:0048082 13 0.044
segmentation GO:0035282 207 0.043
positive regulation of signaling GO:0023056 243 0.043
negative regulation of gene expression GO:0010629 387 0.043
cellular response to chemical stimulus GO:0070887 199 0.043
positive regulation of rna biosynthetic process GO:1902680 266 0.043
organic cyclic compound catabolic process GO:1901361 168 0.042
blastoderm segmentation GO:0007350 159 0.042
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.041
positive regulation of transcription dna templated GO:0045893 266 0.041
imaginal disc derived wing morphogenesis GO:0007476 337 0.041
response to abiotic stimulus GO:0009628 341 0.041
organonitrogen compound metabolic process GO:1901564 318 0.040
positive regulation of response to stimulus GO:0048584 323 0.040
positive regulation of hydrolase activity GO:0051345 78 0.039
purine ribonucleoside metabolic process GO:0046128 127 0.039
regulation of cell morphogenesis GO:0022604 163 0.039
sodium dependent phosphate transport GO:0044341 2 0.038
catabolic process GO:0009056 409 0.038
small gtpase mediated signal transduction GO:0007264 88 0.038
cellular response to organic substance GO:0071310 132 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.037
embryonic pattern specification GO:0009880 174 0.037
intracellular transport GO:0046907 228 0.037
cellular nitrogen compound catabolic process GO:0044270 165 0.037
regulation of response to stress GO:0080134 200 0.036
regulation of multi organism process GO:0043900 131 0.036
phagocytosis GO:0006909 215 0.036
regulation of chitin based cuticle tanning GO:0007564 14 0.036
regionalization GO:0003002 416 0.036
negative regulation of cellular biosynthetic process GO:0031327 277 0.035
aromatic compound catabolic process GO:0019439 166 0.035
regulation of cellular component biogenesis GO:0044087 201 0.035
regulation of intracellular signal transduction GO:1902531 236 0.034
positive regulation of signal transduction GO:0009967 223 0.034
regulation of catabolic process GO:0009894 170 0.033
regulation of cell shape GO:0008360 113 0.033
actin cytoskeleton organization GO:0030036 206 0.033
pigment metabolic process GO:0042440 84 0.033
ras protein signal transduction GO:0007265 88 0.032
nucleoside metabolic process GO:0009116 127 0.031
cell motility GO:0048870 251 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.031
positive regulation of cellular biosynthetic process GO:0031328 316 0.030
response to endogenous stimulus GO:0009719 119 0.030
posttranscriptional regulation of gene expression GO:0010608 145 0.030
negative regulation of cellular metabolic process GO:0031324 382 0.030
nucleoside triphosphate catabolic process GO:0009143 108 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.030
small molecule metabolic process GO:0044281 305 0.030
establishment of localization in cell GO:0051649 402 0.029
organelle fission GO:0048285 340 0.029
cuticle pigmentation GO:0048067 22 0.028
cell division GO:0051301 248 0.027
appendage development GO:0048736 401 0.027
pigmentation GO:0043473 75 0.027
response to lipopolysaccharide GO:0032496 4 0.027
regulation of proteolysis GO:0030162 87 0.027
cell migration GO:0016477 238 0.026
forebrain development GO:0030900 2 0.026
macromolecule catabolic process GO:0009057 161 0.026
transmembrane transport GO:0055085 139 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.026
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.025
regulation of immune system process GO:0002682 176 0.025
regulation of hydrolase activity GO:0051336 97 0.025
regulation of cell cycle GO:0051726 291 0.025
amine metabolic process GO:0009308 12 0.025
developmental pigmentation GO:0048066 68 0.024
response to other organism GO:0051707 293 0.024
positive regulation of macromolecule metabolic process GO:0010604 405 0.024
cellular lipid metabolic process GO:0044255 83 0.024
positive regulation of protein metabolic process GO:0051247 128 0.024
regulation of protein metabolic process GO:0051246 256 0.024
defense response to other organism GO:0098542 225 0.024
carbohydrate derivative metabolic process GO:1901135 217 0.024
regulation of catalytic activity GO:0050790 185 0.024
positive regulation of intracellular signal transduction GO:1902533 116 0.024
single organism cellular localization GO:1902580 180 0.024
single organism intracellular transport GO:1902582 207 0.024
epithelial cell differentiation GO:0030855 322 0.024
negative regulation of rna metabolic process GO:0051253 251 0.024
regulation of immune response GO:0050776 118 0.023
tissue migration GO:0090130 155 0.023
positive regulation of catalytic activity GO:0043085 118 0.023
positive regulation of biosynthetic process GO:0009891 316 0.023
phosphorylation GO:0016310 294 0.023
muscle organ development GO:0007517 127 0.023
positive regulation of molecular function GO:0044093 136 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
protein modification process GO:0036211 438 0.022
response to nitrogen compound GO:1901698 90 0.022
negative regulation of response to stimulus GO:0048585 258 0.021
cell death GO:0008219 279 0.021
enzyme linked receptor protein signaling pathway GO:0007167 179 0.021
oxoacid metabolic process GO:0043436 103 0.021
phenol containing compound metabolic process GO:0018958 57 0.020
regulation of cellular amine metabolic process GO:0033238 3 0.020
organic acid metabolic process GO:0006082 103 0.020
nephron morphogenesis GO:0072028 3 0.020
regulation of anatomical structure morphogenesis GO:0022603 242 0.020
ameboidal type cell migration GO:0001667 151 0.020
cellular macromolecule catabolic process GO:0044265 136 0.020
chromosome organization GO:0051276 360 0.020
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.020
secondary metabolic process GO:0019748 75 0.020
response to bacterium GO:0009617 198 0.019
synaptic transmission GO:0007268 288 0.019
negative regulation of signaling GO:0023057 219 0.019
innate immune response GO:0045087 144 0.019
axon development GO:0061564 297 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.019
regulation of peptidase activity GO:0052547 39 0.019
histolysis GO:0007559 102 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
immune response regulating signaling pathway GO:0002764 2 0.019
negative regulation of transcription dna templated GO:0045892 237 0.019
leg disc development GO:0035218 92 0.019
cellular amine metabolic process GO:0044106 12 0.019
regulation of phosphate metabolic process GO:0019220 210 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.019
cytoplasmic transport GO:0016482 130 0.019
regulation of cellular catabolic process GO:0031329 157 0.019
negative regulation of mitotic cell cycle GO:0045930 109 0.019
intracellular protein transmembrane transport GO:0065002 4 0.019
molting cycle GO:0042303 56 0.018
body morphogenesis GO:0010171 2 0.018
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.018
cell proliferation GO:0008283 299 0.018
macromolecular complex assembly GO:0065003 256 0.018
purine containing compound metabolic process GO:0072521 155 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.018
regulation of mitotic cell cycle GO:0007346 190 0.018
actin filament based process GO:0030029 220 0.018
imaginal disc pattern formation GO:0007447 91 0.018
columnar cuboidal epithelial cell development GO:0002066 249 0.018
tissue death GO:0016271 102 0.018
immune response GO:0006955 246 0.017
organic substance transport GO:0071702 257 0.017
immune system process GO:0002376 347 0.017
central nervous system development GO:0007417 201 0.017
positive regulation of catabolic process GO:0009896 105 0.017
regulation of defense response GO:0031347 102 0.017
nucleobase containing small molecule metabolic process GO:0055086 174 0.017
response to external biotic stimulus GO:0043207 293 0.017
single organism behavior GO:0044708 391 0.017
actin filament organization GO:0007015 126 0.017
kidney epithelium development GO:0072073 3 0.017
glycosyl compound metabolic process GO:1901657 127 0.017
positive regulation of cellular component organization GO:0051130 156 0.016
regulation of small gtpase mediated signal transduction GO:0051056 93 0.016
chemotaxis GO:0006935 249 0.016
regulation of localization GO:0032879 275 0.016
embryonic axis specification GO:0000578 107 0.016
regulation of organelle organization GO:0033043 196 0.016
regulation of ras protein signal transduction GO:0046578 93 0.016
imaginal disc derived leg morphogenesis GO:0007480 80 0.016
single organism catabolic process GO:0044712 228 0.016
lateral inhibition GO:0046331 206 0.016
kidney development GO:0001822 3 0.016
establishment or maintenance of cell polarity GO:0007163 167 0.016
jak stat cascade GO:0007259 49 0.016
regulation of nervous system development GO:0051960 248 0.015
nucleoside triphosphate metabolic process GO:0009141 120 0.015
regulation of transport GO:0051049 181 0.015
positive regulation of cellular protein metabolic process GO:0032270 118 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
epithelial cell development GO:0002064 274 0.015
nucleoside catabolic process GO:0009164 112 0.015
protein transmembrane transport GO:0071806 4 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
glycosyl compound catabolic process GO:1901658 112 0.015
cell fate determination GO:0001709 91 0.015
immune effector process GO:0002252 98 0.015
regulation of immune effector process GO:0002697 52 0.015
dorsal ventral pattern formation GO:0009953 133 0.015
negative regulation of signal transduction GO:0009968 206 0.015
regulation of cell differentiation GO:0045595 302 0.015
cellular response to nitrogen compound GO:1901699 51 0.015
organophosphate catabolic process GO:0046434 112 0.015
regulation of nucleocytoplasmic transport GO:0046822 35 0.015
ribonucleoside triphosphate catabolic process GO:0009203 108 0.014
developmental maturation GO:0021700 172 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
guanosine containing compound catabolic process GO:1901069 74 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
ion transport GO:0006811 145 0.014
gene silencing GO:0016458 138 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
cellular response to oxidative stress GO:0034599 28 0.014
regulation of mrna processing GO:0050684 71 0.014
cellular ketone metabolic process GO:0042180 24 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.013
response to organic cyclic compound GO:0014070 89 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
response to extracellular stimulus GO:0009991 116 0.013
eye antennal disc development GO:0035214 60 0.013
programmed cell death GO:0012501 257 0.013
response to light stimulus GO:0009416 124 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
autophagic cell death GO:0048102 83 0.013
hematopoietic progenitor cell differentiation GO:0002244 1 0.013
connective tissue development GO:0061448 3 0.013
rna processing GO:0006396 147 0.013
epithelial cell migration GO:0010631 148 0.013
endomembrane system organization GO:0010256 119 0.013
kidney morphogenesis GO:0060993 3 0.013
mrna processing GO:0006397 104 0.013
growth GO:0040007 359 0.013
immune response activating signal transduction GO:0002757 2 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
negative regulation of developmental process GO:0051093 201 0.013
anterior posterior axis specification GO:0009948 109 0.013
morphogenesis of embryonic epithelium GO:0016331 94 0.013
salivary gland morphogenesis GO:0007435 145 0.013
nephron development GO:0072006 3 0.013
regulation of hormone levels GO:0010817 40 0.013
tripartite regional subdivision GO:0007351 103 0.013
mrna catabolic process GO:0006402 33 0.013
response to nutrient levels GO:0031667 114 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
male gamete generation GO:0048232 201 0.012
nitrogen compound transport GO:0071705 85 0.012
neurological system process GO:0050877 358 0.012
axon guidance GO:0007411 233 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
regulation of translation GO:0006417 56 0.012
regulation of gtpase activity GO:0043087 44 0.012
negative regulation of nucleic acid templated transcription GO:1903507 240 0.012
nephron tubule development GO:0072080 3 0.012
response to biotic stimulus GO:0009607 294 0.012
anterior posterior axis specification embryo GO:0008595 103 0.012
nuclear division GO:0000280 332 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
regulation of intracellular transport GO:0032386 64 0.012
purine nucleotide catabolic process GO:0006195 109 0.012
regulation of epithelial cell proliferation GO:0050678 4 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
cellular response to endogenous stimulus GO:0071495 80 0.012
cell adhesion GO:0007155 136 0.012
positive regulation of cell differentiation GO:0045597 64 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
regulation of reproductive process GO:2000241 54 0.012
nephron epithelium development GO:0072009 3 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
nucleotide metabolic process GO:0009117 161 0.012
humoral immune response GO:0006959 117 0.012
rna localization GO:0006403 115 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
ovarian follicle cell development GO:0030707 248 0.011
regulation of cellular localization GO:0060341 136 0.011
response to hypoxia GO:0001666 53 0.011
protein processing GO:0016485 68 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
negative regulation of immune response GO:0050777 39 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
anterior posterior pattern specification GO:0009952 136 0.011
molting cycle process GO:0022404 29 0.011
nephron tubule morphogenesis GO:0072078 3 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
death GO:0016265 284 0.011
gtp catabolic process GO:0006184 72 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
cuticle development GO:0042335 86 0.011
intracellular mrna localization GO:0008298 66 0.011
multicellular organismal aging GO:0010259 140 0.011
wing disc pattern formation GO:0035222 66 0.011
telencephalon development GO:0021537 2 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
biological adhesion GO:0022610 138 0.011
protein maturation GO:0051604 71 0.011
regulation of cell death GO:0010941 173 0.011
protein complex biogenesis GO:0070271 201 0.011
leg disc morphogenesis GO:0007478 80 0.011
muscle structure development GO:0061061 224 0.010
regulation of phosphorylation GO:0042325 147 0.010
response to organonitrogen compound GO:0010243 75 0.010
developmental growth GO:0048589 280 0.010
adult behavior GO:0030534 137 0.010
regulation of nucleoside metabolic process GO:0009118 50 0.010
response to oxygen levels GO:0070482 59 0.010
gene silencing by rna GO:0031047 57 0.010
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.010
anion transport GO:0006820 41 0.010
spermatogenesis GO:0007283 200 0.010
modification dependent protein catabolic process GO:0019941 78 0.010
cellular macromolecule localization GO:0070727 220 0.010

slim disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.016
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
disease of anatomical entity DOID:7 0 0.015
inherited metabolic disorder DOID:655 0 0.010