Drosophila melanogaster

0 known processes

Nup154 (Dmel_CG4579)

Nucleoporin 154

(Aliases: Dmel\CG4579,l(2)01501,zk,Nup32D,tip,BcDNA:LD21772,nup32D,CG4579,tlp,ms(2)zk,l(2)10432,nup154)

Nup154 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular component assembly involved in morphogenesis GO:0010927 151 0.986
dna conformation change GO:0071103 105 0.840
germ line cyst formation GO:0048134 44 0.836
eggshell chorion assembly GO:0007306 66 0.807
pole plasm assembly GO:0007315 61 0.793
eggshell formation GO:0030703 105 0.775
catabolic process GO:0009056 409 0.774
chorion containing eggshell formation GO:0007304 105 0.737
establishment of localization in cell GO:0051649 402 0.729
Mouse Worm
cellular catabolic process GO:0044248 372 0.672
spermatogenesis GO:0007283 200 0.656
dorsal appendage formation GO:0046843 47 0.629
macromolecular complex assembly GO:0065003 256 0.592
epithelial cell differentiation GO:0030855 322 0.589
cystoblast division GO:0007282 10 0.578
cytoplasmic transport GO:0016482 130 0.532
Mouse
heterocycle catabolic process GO:0046700 166 0.518
chromosome condensation GO:0030261 41 0.480
nucleobase containing compound catabolic process GO:0034655 165 0.480
spermatid differentiation GO:0048515 114 0.475
female germ line cyst formation GO:0048135 42 0.474
mrna metabolic process GO:0016071 124 0.467
germarium derived female germ line cyst formation GO:0030727 42 0.450
cell proliferation GO:0008283 299 0.443
dna metabolic process GO:0006259 227 0.397
dna packaging GO:0006323 91 0.373
germarium derived egg chamber formation GO:0007293 101 0.355
organic substance transport GO:0071702 257 0.336
Mouse
protein localization GO:0008104 284 0.333
Mouse
centrosome cycle GO:0007098 137 0.324
centrosome organization GO:0051297 163 0.312
oocyte construction GO:0007308 112 0.310
organelle assembly GO:0070925 198 0.308
organelle fission GO:0048285 340 0.293
negative regulation of oskar mrna translation GO:0007319 5 0.291
maternal determination of anterior posterior axis embryo GO:0008358 74 0.290
regulation of cell differentiation GO:0045595 302 0.275
localization of cell GO:0051674 257 0.257
aromatic compound catabolic process GO:0019439 166 0.247
microtubule organizing center organization GO:0031023 168 0.238
cellular macromolecule localization GO:0070727 220 0.231
Mouse
development of primary sexual characteristics GO:0045137 50 0.228
Worm
nucleoside metabolic process GO:0009116 127 0.228
negative regulation of developmental process GO:0051093 201 0.227
developmental growth GO:0048589 280 0.222
regulation of cellular catabolic process GO:0031329 157 0.216
protein targeting GO:0006605 64 0.215
Mouse
organic cyclic compound catabolic process GO:1901361 168 0.204
cellular macromolecular complex assembly GO:0034622 153 0.194
oocyte anterior posterior axis specification GO:0007314 72 0.191
embryonic pattern specification GO:0009880 174 0.188
posttranscriptional regulation of gene expression GO:0010608 145 0.182
growth GO:0040007 359 0.167
cellular nitrogen compound catabolic process GO:0044270 165 0.161
male gamete generation GO:0048232 201 0.153
enzyme linked receptor protein signaling pathway GO:0007167 179 0.149
negative regulation of gene expression GO:0010629 387 0.149
carbohydrate derivative metabolic process GO:1901135 217 0.149
mrna catabolic process GO:0006402 33 0.143
muscle structure development GO:0061061 224 0.142
single organism behavior GO:0044708 391 0.141
macromolecule catabolic process GO:0009057 161 0.141
mitotic spindle organization GO:0007052 220 0.134
segmentation GO:0035282 207 0.133
embryo development ending in birth or egg hatching GO:0009792 152 0.132
Worm
negative regulation of translation GO:0017148 28 0.130
regulation of meiotic cell cycle GO:0051445 9 0.128
posttranscriptional gene silencing by rna GO:0035194 45 0.126
establishment of protein localization GO:0045184 163 0.124
Mouse
embryonic axis specification GO:0000578 107 0.121
single organism cellular localization GO:1902580 180 0.121
Mouse
exocrine system development GO:0035272 162 0.120
mrna processing GO:0006397 104 0.117
organic substance catabolic process GO:1901575 308 0.117
nucleoside triphosphate metabolic process GO:0009141 120 0.116
protein complex assembly GO:0006461 200 0.116
purine nucleoside triphosphate catabolic process GO:0009146 108 0.111
oocyte dorsal ventral axis specification GO:0007310 34 0.110
mitotic nuclear division GO:0007067 213 0.108
regulation of oskar mrna translation GO:0046011 8 0.107
cellular protein complex assembly GO:0043623 71 0.104
chromosome organization GO:0051276 360 0.103
negative regulation of cell differentiation GO:0045596 143 0.102
purine containing compound metabolic process GO:0072521 155 0.101
pole plasm protein localization GO:0007318 10 0.099
ribonucleoside triphosphate catabolic process GO:0009203 108 0.096
nuclear pore organization GO:0006999 1 0.095
protein import GO:0017038 55 0.095
Mouse
nucleobase containing small molecule metabolic process GO:0055086 174 0.095
single organism intracellular transport GO:1902582 207 0.094
Mouse
purine nucleoside metabolic process GO:0042278 127 0.092
body morphogenesis GO:0010171 2 0.092
tissue morphogenesis GO:0048729 297 0.088
glycosyl compound metabolic process GO:1901657 127 0.088
purine nucleotide metabolic process GO:0006163 146 0.088
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.087
epithelial cell development GO:0002064 274 0.086
larval development GO:0002164 104 0.084
Worm
protein complex biogenesis GO:0070271 201 0.083
regulation of catabolic process GO:0009894 170 0.083
oocyte microtubule cytoskeleton organization GO:0016325 35 0.083
oocyte maturation GO:0001556 3 0.082
purine ribonucleotide metabolic process GO:0009150 145 0.081
regulation of meiosis GO:0040020 3 0.078
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.077
spermatid development GO:0007286 98 0.077
ribonucleoside metabolic process GO:0009119 127 0.076
gland development GO:0048732 191 0.075
ribonucleoprotein complex assembly GO:0022618 23 0.074
protein import into nucleus GO:0006606 51 0.074
Mouse
lipid metabolic process GO:0006629 121 0.073
sister chromatid segregation GO:0000819 92 0.071
gene silencing by rna GO:0031047 57 0.071
morphogenesis of an epithelium GO:0002009 276 0.071
homeostatic process GO:0042592 199 0.070
stem cell division GO:0017145 69 0.070
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.070
glycosyl compound catabolic process GO:1901658 112 0.070
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.069
germarium derived oocyte fate determination GO:0007294 26 0.068
meiotic cell cycle GO:0051321 171 0.068
mitotic sister chromatid segregation GO:0000070 87 0.068
regulation of dna metabolic process GO:0051052 34 0.068
gonad development GO:0008406 50 0.067
Worm
cell motility GO:0048870 251 0.066
purine containing compound catabolic process GO:0072523 112 0.065
nucleocytoplasmic transport GO:0006913 72 0.065
Mouse
cellular protein localization GO:0034613 160 0.065
Mouse
ribonucleotide metabolic process GO:0009259 145 0.064
protein localization to organelle GO:0033365 82 0.062
Mouse
oocyte axis specification GO:0007309 108 0.062
death GO:0016265 284 0.062
negative regulation of signaling GO:0023057 219 0.062
nucleoside catabolic process GO:0009164 112 0.062
g2 m transition of mitotic cell cycle GO:0000086 19 0.060
rna processing GO:0006396 147 0.060
mitotic cell cycle phase transition GO:0044772 138 0.058
single organism catabolic process GO:0044712 228 0.058
rna splicing GO:0008380 83 0.057
intracellular mrna localization GO:0008298 66 0.057
head development GO:0060322 135 0.056
purine ribonucleoside metabolic process GO:0046128 127 0.056
organonitrogen compound catabolic process GO:1901565 128 0.054
genitalia development GO:0048806 26 0.053
Worm
nuclear division GO:0000280 332 0.052
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.051
negative regulation of cellular biosynthetic process GO:0031327 277 0.051
attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation GO:0051316 1 0.051
anterior posterior axis specification GO:0009948 109 0.050
nuclear transport GO:0051169 72 0.049
Mouse
positive regulation of cell cycle GO:0045787 43 0.049
chromosome segregation GO:0007059 157 0.049
blastoderm segmentation GO:0007350 159 0.049
purine ribonucleotide catabolic process GO:0009154 109 0.048
organonitrogen compound metabolic process GO:1901564 318 0.047
asymmetric cell division GO:0008356 37 0.046
stem cell development GO:0048864 79 0.046
regulation of localization GO:0032879 275 0.044
Mouse
regulation of cell division GO:0051302 72 0.043
carbohydrate derivative catabolic process GO:1901136 118 0.043
endomembrane system organization GO:0010256 119 0.043
Human
regulation of developmental growth GO:0048638 174 0.043
cellular macromolecule catabolic process GO:0044265 136 0.042
regulation of transposition GO:0010528 13 0.041
nucleoside triphosphate catabolic process GO:0009143 108 0.039
purine nucleoside triphosphate metabolic process GO:0009144 119 0.039
purine ribonucleoside catabolic process GO:0046130 112 0.039
negative regulation of mitotic anaphase promoting complex activity GO:0060564 2 0.039
rna splicing via transesterification reactions GO:0000375 73 0.039
translation GO:0006412 69 0.039
karyosome formation GO:0030717 22 0.039
salivary gland morphogenesis GO:0007435 145 0.037
germ line stem cell division GO:0042078 25 0.037
salivary gland development GO:0007431 162 0.036
vesicle mediated transport GO:0016192 381 0.036
ribose phosphate metabolic process GO:0019693 145 0.036
ribonucleoside catabolic process GO:0042454 112 0.035
purine nucleoside monophosphate metabolic process GO:0009126 50 0.035
establishment or maintenance of cell polarity GO:0007163 167 0.034
regulation of cellular localization GO:0060341 136 0.034
anterior posterior axis specification embryo GO:0008595 103 0.033
mitotic cell cycle embryonic GO:0045448 38 0.033
maternal determination of dorsal ventral axis ovarian follicular epithelium germ line encoded GO:0008070 2 0.032
protein transport GO:0015031 155 0.032
Mouse
axoneme assembly GO:0035082 18 0.031
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.030
lateral inhibition GO:0046331 206 0.030
purine nucleoside catabolic process GO:0006152 112 0.029
response to wounding GO:0009611 94 0.029
positive regulation of hydrolase activity GO:0051345 78 0.029
ovarian follicle cell development GO:0030707 248 0.029
chromosome organization involved in meiosis GO:0070192 10 0.029
ribonucleotide catabolic process GO:0009261 109 0.028
organelle inheritance GO:0048308 2 0.028
actin cytoskeleton organization GO:0030036 206 0.028
maintenance of protein location GO:0045185 28 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.027
regulation of pole plasm oskar mrna localization GO:0007317 27 0.027
nucleoside phosphate catabolic process GO:1901292 110 0.027
gene silencing GO:0016458 138 0.027
organophosphate metabolic process GO:0019637 195 0.027
smad protein import into nucleus GO:0007184 11 0.026
nucleotide catabolic process GO:0009166 109 0.026
immune system process GO:0002376 347 0.026
sex differentiation GO:0007548 81 0.026
Worm
ribonucleoprotein complex subunit organization GO:0071826 28 0.026
endocytosis GO:0006897 310 0.026
regulation of neurogenesis GO:0050767 158 0.026
regulation of mrna metabolic process GO:1903311 72 0.026
male meiosis GO:0007140 52 0.026
digestive tract morphogenesis GO:0048546 127 0.026
protein targeting to nucleus GO:0044744 51 0.025
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.025
stem cell maintenance GO:0019827 67 0.025
negative regulation of cellular component organization GO:0051129 108 0.025
regulation of cell cycle GO:0051726 291 0.025
secretion GO:0046903 109 0.025
Worm
posttranscriptional gene silencing GO:0016441 46 0.025
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.024
regulation of cell proliferation GO:0042127 163 0.024
organophosphate catabolic process GO:0046434 112 0.024
compound eye development GO:0048749 307 0.024
small molecule metabolic process GO:0044281 305 0.023
rna interference GO:0016246 27 0.023
regulation of transport GO:0051049 181 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.023
nucleoside monophosphate catabolic process GO:0009125 39 0.023
urogenital system development GO:0001655 72 0.023
positive regulation of multicellular organismal process GO:0051240 143 0.023
maintenance of location GO:0051235 73 0.022
Worm
mitotic chromosome condensation GO:0007076 22 0.022
negative regulation of cellular metabolic process GO:0031324 382 0.022
negative regulation of nurse cell apoptotic process GO:0045849 2 0.021
nucleus organization GO:0006997 45 0.021
Human Worm
negative regulation of nucleotide metabolic process GO:0045980 4 0.021
dna replication GO:0006260 48 0.021
digestive system development GO:0055123 149 0.021
chromatin remodeling GO:0006338 72 0.020
positive regulation of developmental process GO:0051094 143 0.020
nucleoside monophosphate metabolic process GO:0009123 52 0.020
imaginal disc growth GO:0007446 37 0.020
fertilization GO:0009566 26 0.020
nucleotide metabolic process GO:0009117 161 0.020
regulation of striated muscle contraction GO:0006942 2 0.020
Mouse
organ growth GO:0035265 56 0.020
regulation of multicellular organismal development GO:2000026 414 0.020
regulation of intracellular transport GO:0032386 64 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.019
cellular response to nutrient GO:0031670 1 0.019
positive regulation of catabolic process GO:0009896 105 0.019
regulation of gene expression epigenetic GO:0040029 128 0.019
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.019
dendrite regeneration GO:0031104 2 0.019
ubiquitin dependent protein catabolic process GO:0006511 78 0.018
embryonic morphogenesis GO:0048598 206 0.018
regulation of response to stress GO:0080134 200 0.018
axon development GO:0061564 297 0.018
regulation of hemocyte proliferation GO:0035206 37 0.017
hindgut development GO:0061525 58 0.017
stem cell differentiation GO:0048863 117 0.017
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 2 0.017
gland morphogenesis GO:0022612 145 0.017
negative regulation of cellular protein metabolic process GO:0032269 85 0.017
regulation of cell cycle phase transition GO:1901987 130 0.017
negative regulation of response to stimulus GO:0048585 258 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
regulation of establishment of protein localization GO:0070201 61 0.016
positive regulation of cell differentiation GO:0045597 64 0.016
regulation of histone methylation GO:0031060 10 0.016
regulation of molecular function GO:0065009 217 0.016
compound eye morphogenesis GO:0001745 249 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.015
protein catabolic process GO:0030163 101 0.015
nuclear transcribed mrna catabolic process GO:0000956 24 0.015
spindle organization GO:0007051 253 0.015
central nervous system development GO:0007417 201 0.015
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.015
muscle cell differentiation GO:0042692 103 0.015
histone h3 k9 modification GO:0061647 12 0.015
chromatin assembly or disassembly GO:0006333 52 0.015
establishment of ommatidial planar polarity GO:0042067 49 0.015
intracellular protein transport GO:0006886 104 0.015
Mouse
neuroblast proliferation GO:0007405 74 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
regulation of nucleoside metabolic process GO:0009118 50 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
establishment of nucleus localization GO:0040023 26 0.014
positive regulation of apoptotic signaling pathway GO:2001235 4 0.014
photoreceptor cell differentiation GO:0046530 170 0.014
positive regulation of biosynthetic process GO:0009891 316 0.014
positive regulation of molecular function GO:0044093 136 0.014
chitin based larval cuticle pattern formation GO:0035293 11 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
regulation of hydrolase activity GO:0051336 97 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
positive regulation of response to stimulus GO:0048584 323 0.013
meiotic dna repair synthesis GO:0000711 3 0.013
positive regulation of mitotic cell cycle GO:0045931 34 0.012
epithelial cell fate determination open tracheal system GO:0007425 2 0.012
oocyte morphogenesis GO:0048601 3 0.012
eye development GO:0001654 323 0.012
regulation of cell proliferation involved in compound eye morphogenesis GO:2000495 2 0.012
nuclear envelope organization GO:0006998 7 0.012
Human
regulation of cdc42 protein signal transduction GO:0032489 3 0.012
positive regulation of cell development GO:0010720 61 0.012
eye morphogenesis GO:0048592 260 0.012
single organism nuclear import GO:1902593 51 0.012
Mouse
maternal determination of dorsal ventral axis ovarian follicular epithelium soma encoded GO:0008071 1 0.012
carboxylic acid metabolic process GO:0019752 92 0.011
nitrogen compound transport GO:0071705 85 0.011
Mouse
locomotory behavior GO:0007626 176 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
lymph gland development GO:0048542 28 0.011
positive regulation of multicellular organism growth GO:0040018 21 0.011
ion transport GO:0006811 145 0.011
regulation of viral genome replication GO:0045069 4 0.011
dorsal closure leading edge cell differentiation GO:0046663 2 0.011
ribonucleoside monophosphate metabolic process GO:0009161 51 0.011
regulation of proteasomal protein catabolic process GO:0061136 39 0.011
oenocyte delamination GO:0060233 2 0.011
tube development GO:0035295 244 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
chromatin modification GO:0016568 147 0.011
pole plasm mrna localization GO:0019094 49 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.010
axis specification GO:0009798 167 0.010
regulation of transmembrane transport GO:0034762 27 0.010
centriole replication GO:0007099 24 0.010
meiotic cell cycle process GO:1903046 132 0.010
regulation of mrna splicing via spliceosome GO:0048024 64 0.010
regulation of planar cell polarity pathway involved in axis elongation GO:2000040 2 0.010
regulation of rna splicing GO:0043484 69 0.010
negative regulation of terminal cell fate specification open tracheal system GO:0035155 2 0.010

Nup154 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
syndrome DOID:225 0 0.033
cancer DOID:162 0 0.026
disease of cellular proliferation DOID:14566 0 0.026
organ system cancer DOID:0050686 0 0.016