Drosophila melanogaster

5 known processes

Cyp12a4 (Dmel_CG6042)

CG6042 gene product from transcript CG6042-RA

(Aliases: Dmel\CG6042,cyp12a4,12a4,P450,CG6042,CYP12A4)

Cyp12a4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
insecticide metabolic process GO:0017143 2 1.000
secondary metabolite catabolic process GO:0090487 1 0.998
medium chain fatty acid metabolic process GO:0051791 1 0.995
response to mercury ion GO:0046689 3 0.993
toxin catabolic process GO:0009407 1 0.990
insecticide catabolic process GO:0046701 1 0.984
lauric acid metabolic process GO:0048252 1 0.980
response to toxic substance GO:0009636 22 0.974
organic hydroxy compound biosynthetic process GO:1901617 21 0.944
Fly
response to ddt GO:0046680 5 0.913
Fly
steroid catabolic process GO:0006706 1 0.895
ketone biosynthetic process GO:0042181 16 0.879
Fly
polyol biosynthetic process GO:0046173 3 0.874
fat soluble vitamin biosynthetic process GO:0042362 1 0.857
vitamin biosynthetic process GO:0009110 1 0.843
regulation of tube size GO:0035150 46 0.824
sterol metabolic process GO:0016125 12 0.810
Fly
xenobiotic catabolic process GO:0042178 1 0.789
cellular hormone metabolic process GO:0034754 23 0.755
Fly
vitamin metabolic process GO:0006766 2 0.736
steroid biosynthetic process GO:0006694 16 0.732
Fly
response to insecticide GO:0017085 14 0.717
organic hydroxy compound metabolic process GO:1901615 83 0.700
Fly
alcohol biosynthetic process GO:0046165 14 0.679
Fly
anion homeostasis GO:0055081 3 0.678
multi organism behavior GO:0051705 175 0.648
aggressive behavior GO:0002118 63 0.634
ecdysone biosynthetic process GO:0006697 9 0.601
Fly
sensory perception of smell GO:0007608 80 0.591
tissue migration GO:0090130 155 0.590
Fly
sterol biosynthetic process GO:0016126 9 0.577
Fly
response to caffeine GO:0031000 12 0.572
fatty acid metabolic process GO:0006631 20 0.565
hormone biosynthetic process GO:0042446 20 0.552
Fly
fat soluble vitamin metabolic process GO:0006775 1 0.510
sensory perception of chemical stimulus GO:0007606 116 0.499
ecdysteroid biosynthetic process GO:0045456 15 0.464
Fly
response to organophosphorus GO:0046683 2 0.462
response to organic substance GO:0010033 284 0.457
Fly
positive regulation of multicellular organismal process GO:0051240 143 0.437
alcohol metabolic process GO:0006066 25 0.431
Fly
lipid catabolic process GO:0016042 21 0.419
regulation of anatomical structure size GO:0090066 163 0.416
response to xenobiotic stimulus GO:0009410 5 0.404
ecdysone metabolic process GO:0008205 11 0.404
Fly
single organism biosynthetic process GO:0044711 206 0.388
Fly
sensory perception GO:0007600 196 0.386
organonitrogen compound catabolic process GO:1901565 128 0.357
small molecule metabolic process GO:0044281 305 0.353
Fly
developmental growth GO:0048589 280 0.344
Fly
response to nitrogen compound GO:1901698 90 0.341
secondary metabolic process GO:0019748 75 0.332
epithelium migration GO:0090132 148 0.321
Fly
ovarian follicle cell migration GO:0007297 121 0.318
Fly
growth GO:0040007 359 0.304
Fly
cellular ketone metabolic process GO:0042180 24 0.303
Fly
steroid metabolic process GO:0008202 20 0.300
Fly
lipid biosynthetic process GO:0008610 46 0.296
Fly
toxin metabolic process GO:0009404 2 0.293
regulation of developmental growth GO:0048638 174 0.289
ecdysteroid metabolic process GO:0045455 19 0.287
Fly
cellular ion homeostasis GO:0006873 39 0.283
response to purine containing compound GO:0014074 12 0.261
terpenoid metabolic process GO:0006721 7 0.258
positive regulation of gene expression GO:0010628 290 0.254
cellular catabolic process GO:0044248 372 0.252
epithelial cell development GO:0002064 274 0.252
Fly
chemical homeostasis GO:0048878 92 0.251
response to temperature stimulus GO:0009266 106 0.247
lipid metabolic process GO:0006629 121 0.244
Fly
neurological system process GO:0050877 358 0.238
response to organic cyclic compound GO:0014070 89 0.227
Fly
cellular lipid metabolic process GO:0044255 83 0.226
oxidation reduction process GO:0055114 123 0.226
Fly
isoprenoid metabolic process GO:0006720 8 0.225
response to external biotic stimulus GO:0043207 293 0.218
small molecule biosynthetic process GO:0044283 37 0.215
Fly
hormone metabolic process GO:0042445 33 0.215
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.214
dorsal closure GO:0007391 79 0.211
Fly
monocarboxylic acid metabolic process GO:0032787 29 0.209
catabolic process GO:0009056 409 0.207
organonitrogen compound metabolic process GO:1901564 318 0.206
carboxylic acid metabolic process GO:0019752 92 0.203
response to metal ion GO:0010038 23 0.199
response to alkaloid GO:0043279 26 0.199
regulation of system process GO:0044057 36 0.198
homeostatic process GO:0042592 199 0.183
single organism catabolic process GO:0044712 228 0.181
organic cyclic compound catabolic process GO:1901361 168 0.175
ameboidal type cell migration GO:0001667 151 0.167
Fly
organic acid metabolic process GO:0006082 103 0.165
response to abiotic stimulus GO:0009628 341 0.163
organic substance catabolic process GO:1901575 308 0.160
cellular nitrogen compound catabolic process GO:0044270 165 0.160
ion homeostasis GO:0050801 55 0.154
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.152
Fly
response to lipid GO:0033993 38 0.151
embryonic development via the syncytial blastoderm GO:0001700 148 0.145
Fly
defense response to bacterium GO:0042742 178 0.141
response to other organism GO:0051707 293 0.137
single organism behavior GO:0044708 391 0.135
border follicle cell migration GO:0007298 113 0.132
Fly
response to endogenous stimulus GO:0009719 119 0.129
cellular chemical homeostasis GO:0055082 40 0.127
response to biotic stimulus GO:0009607 294 0.127
cellular homeostasis GO:0019725 80 0.126
response to extracellular stimulus GO:0009991 116 0.125
regulation of growth GO:0040008 233 0.120
response to nutrient levels GO:0031667 114 0.114
regulation of blood circulation GO:1903522 21 0.113
response to inorganic substance GO:0010035 44 0.109
defense response to other organism GO:0098542 225 0.107
response to organonitrogen compound GO:0010243 75 0.106
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.098
Fly
response to bacterium GO:0009617 198 0.097
gland development GO:0048732 191 0.097
tergite morphogenesis GO:0007490 1 0.096
Fly
tissue morphogenesis GO:0048729 297 0.093
Fly
cell motility GO:0048870 251 0.092
Fly
defense response GO:0006952 300 0.081
cellular response to chemical stimulus GO:0070887 199 0.078
ovarian follicle cell development GO:0030707 248 0.078
Fly
response to oxygen containing compound GO:1901700 200 0.075
appendage development GO:0048736 401 0.075
aging GO:0007568 143 0.074
epithelial cell migration GO:0010631 148 0.073
Fly
cell migration GO:0016477 238 0.071
Fly
imaginal disc derived appendage development GO:0048737 399 0.070
localization of cell GO:0051674 257 0.070
Fly
regulation of hormone levels GO:0010817 40 0.069
Fly
acetate ester metabolic process GO:1900619 2 0.068
morphogenesis of an epithelium GO:0002009 276 0.064
Fly
defense response to gram negative bacterium GO:0050829 94 0.064
response to hormone GO:0009725 45 0.063
oxoacid metabolic process GO:0043436 103 0.063
circulatory system process GO:0003013 37 0.062
hormone catabolic process GO:0042447 3 0.062
epithelial cell differentiation GO:0030855 322 0.062
Fly
imaginal disc derived appendage morphogenesis GO:0035114 395 0.062
wing disc morphogenesis GO:0007472 344 0.062
response to transition metal nanoparticle GO:1990267 9 0.060
synaptic transmission GO:0007268 288 0.060
digestive tract development GO:0048565 149 0.057
Fly
androgen metabolic process GO:0008209 1 0.056
central nervous system development GO:0007417 201 0.055
Fly
morphogenesis of embryonic epithelium GO:0016331 94 0.054
Fly
positive regulation of response to stimulus GO:0048584 323 0.052
embryonic morphogenesis GO:0048598 206 0.050
Fly
response to lipopolysaccharide GO:0032496 4 0.050
chitin based cuticle development GO:0040003 49 0.047
Fly
detection of stimulus GO:0051606 156 0.047
xenobiotic metabolic process GO:0006805 5 0.046
heterocycle catabolic process GO:0046700 166 0.045
response to alcohol GO:0097305 95 0.045
aromatic compound catabolic process GO:0019439 166 0.045
blood circulation GO:0008015 26 0.044
meiotic cell cycle process GO:1903046 132 0.044
cuticle development GO:0042335 86 0.044
Fly
mitotic spindle organization GO:0007052 220 0.042
columnar cuboidal epithelial cell development GO:0002066 249 0.041
Fly
embryo development ending in birth or egg hatching GO:0009792 152 0.041
Fly
regulation of multicellular organismal development GO:2000026 414 0.040
head involution GO:0008258 35 0.040
Fly
post embryonic appendage morphogenesis GO:0035120 385 0.039
acetylcholine metabolic process GO:0008291 2 0.038
cell proliferation GO:0008283 299 0.038
positive regulation of cell migration GO:0030335 2 0.037
midgut development GO:0007494 23 0.037
Fly
spindle organization GO:0007051 253 0.037
protein modification process GO:0036211 438 0.036
protein complex biogenesis GO:0070271 201 0.035
regulation of localization GO:0032879 275 0.035
imaginal disc derived wing morphogenesis GO:0007476 337 0.035
cellular response to xenobiotic stimulus GO:0071466 5 0.035
chaeta development GO:0022416 97 0.035
digestive system development GO:0055123 149 0.035
Fly
protein complex assembly GO:0006461 200 0.035
cellular amine metabolic process GO:0044106 12 0.035
response to copper ion GO:0046688 4 0.034
telencephalon development GO:0021537 2 0.033
cellular amino acid metabolic process GO:0006520 61 0.033
estrogen metabolic process GO:0008210 1 0.032
multicellular organismal reproductive behavior GO:0033057 110 0.032
forebrain development GO:0030900 2 0.032
regulation of cellular ketone metabolic process GO:0010565 3 0.031
multi organism reproductive behavior GO:0044705 121 0.031
appendage morphogenesis GO:0035107 397 0.030
vesicle mediated transport GO:0016192 381 0.030
macromolecular complex assembly GO:0065003 256 0.030
cell death GO:0008219 279 0.030
programmed cell death GO:0012501 257 0.029
phototransduction GO:0007602 52 0.029
response to drug GO:0042493 17 0.029
kidney development GO:0001822 3 0.029
positive regulation of cell motility GO:2000147 3 0.029
transmembrane transport GO:0055085 139 0.028
neuron recognition GO:0008038 101 0.028
response to cadmium ion GO:0046686 9 0.028
positive regulation of signal transduction GO:0009967 223 0.027
death GO:0016265 284 0.027
regulation of behavior GO:0050795 75 0.027
regulation of multi organism process GO:0043900 131 0.026
thermosensory behavior GO:0040040 19 0.026
cellular protein modification process GO:0006464 438 0.025
multi multicellular organism process GO:0044706 123 0.025
endocytosis GO:0006897 310 0.025
regulation of reproductive process GO:2000241 54 0.024
meiotic nuclear division GO:0007126 151 0.024
mitotic spindle elongation GO:0000022 81 0.024
regulation of molecular function GO:0065009 217 0.024
intracellular signal transduction GO:0035556 300 0.023
negative regulation of cellular biosynthetic process GO:0031327 277 0.023
actin filament organization GO:0007015 126 0.022
tube development GO:0035295 244 0.022
Fly
positive regulation of cell communication GO:0010647 250 0.022
ethanolamine containing compound metabolic process GO:0042439 4 0.022
tissue death GO:0016271 102 0.021
regulation of transport GO:0051049 181 0.021
camera type eye development GO:0043010 4 0.021
autophagic cell death GO:0048102 83 0.020
response to ethanol GO:0045471 59 0.020
water homeostasis GO:0030104 3 0.020
chromosome segregation GO:0007059 157 0.020
phosphorylation GO:0016310 294 0.020
determination of adult lifespan GO:0008340 137 0.020
response to monosaccharide GO:0034284 4 0.020
acetylcholine catabolic process GO:0006581 1 0.019
phagocytosis GO:0006909 215 0.019
benzene containing compound metabolic process GO:0042537 3 0.019
gland morphogenesis GO:0022612 145 0.019
amine metabolic process GO:0009308 12 0.019
positive regulation of signaling GO:0023056 243 0.019
exocrine system development GO:0035272 162 0.018
salivary gland morphogenesis GO:0007435 145 0.018
inter male aggressive behavior GO:0002121 60 0.018
single organism intracellular transport GO:1902582 207 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.018
cellular response to nitrogen compound GO:1901699 51 0.018
neurotransmitter metabolic process GO:0042133 2 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.018
negative regulation of biosynthetic process GO:0009890 277 0.018
cellular response to organic substance GO:0071310 132 0.018
protein transport GO:0015031 155 0.018
regulation of response to stress GO:0080134 200 0.018
cellular response to ketone GO:1901655 17 0.018
regulation of oviposition GO:0046662 14 0.018
nucleoside catabolic process GO:0009164 112 0.017
positive regulation of cellular component biogenesis GO:0044089 80 0.017
reproductive behavior GO:0019098 122 0.017
salivary gland cell autophagic cell death GO:0035071 83 0.017
mrna processing GO:0006397 104 0.017
response to glucose GO:0009749 2 0.017
motor neuron axon guidance GO:0008045 58 0.017
positive regulation of cellular component organization GO:0051130 156 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
synapse assembly GO:0007416 143 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
female meiotic division GO:0007143 70 0.016
axon guidance GO:0007411 233 0.016
small molecule catabolic process GO:0044282 21 0.015
positive regulation of molecular function GO:0044093 136 0.015
multicellular organismal aging GO:0010259 140 0.015
nucleocytoplasmic transport GO:0006913 72 0.015
positive regulation of intracellular signal transduction GO:1902533 116 0.015
renal system process GO:0003014 12 0.015
organic substance transport GO:0071702 257 0.015
synaptic target recognition GO:0008039 45 0.015
positive regulation of transport GO:0051050 92 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
intracellular transport GO:0046907 228 0.015
pyridine containing compound metabolic process GO:0072524 3 0.015
negative regulation of cellular metabolic process GO:0031324 382 0.014
cellular protein complex disassembly GO:0043624 35 0.014
establishment of localization in cell GO:0051649 402 0.014
detection of light stimulus GO:0009583 58 0.014
cellular biogenic amine catabolic process GO:0042402 1 0.014
cellular response to ethanol GO:0071361 4 0.014
response to oxidative stress GO:0006979 86 0.014
cellular response to hexose stimulus GO:0071331 1 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
response to light stimulus GO:0009416 124 0.014
maintenance of location GO:0051235 73 0.014
regulation of programmed cell death GO:0043067 152 0.013
salivary gland development GO:0007431 162 0.013
cellular response to organonitrogen compound GO:0071417 36 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
negative regulation of rna metabolic process GO:0051253 251 0.013
brain development GO:0007420 120 0.013
organophosphate catabolic process GO:0046434 112 0.013
cell recognition GO:0008037 102 0.013
single organism carbohydrate metabolic process GO:0044723 72 0.013
axonogenesis GO:0007409 290 0.013
immune response activating signal transduction GO:0002757 2 0.013
cell projection assembly GO:0030031 94 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
detection of abiotic stimulus GO:0009582 66 0.012
response to radiation GO:0009314 155 0.012
female meiosis chromosome segregation GO:0016321 33 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
choline metabolic process GO:0019695 1 0.012
developmental maturation GO:0021700 172 0.012
epidermis development GO:0008544 65 0.012
axon development GO:0061564 297 0.012
macromolecular complex disassembly GO:0032984 37 0.012
pattern recognition receptor signaling pathway GO:0002221 2 0.012
neurotransmitter catabolic process GO:0042135 1 0.012
synapse organization GO:0050808 196 0.012
neuron projection guidance GO:0097485 241 0.012
respiratory system development GO:0060541 213 0.012
mrna splicing via spliceosome GO:0000398 73 0.012
glutamate metabolic process GO:0006536 5 0.012
cellular response to peptide GO:1901653 28 0.012
activation of innate immune response GO:0002218 4 0.012
regulation of cell death GO:0010941 173 0.011
regionalization GO:0003002 416 0.011
protein localization GO:0008104 284 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
organelle fission GO:0048285 340 0.011
maintenance of imaginal disc derived wing hair orientation GO:0035321 3 0.011
body morphogenesis GO:0010171 2 0.011
open tracheal system development GO:0007424 204 0.011
head development GO:0060322 135 0.011
choline catabolic process GO:0042426 1 0.011
regulation of cell differentiation GO:0045595 302 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
regulation of apoptotic process GO:0042981 130 0.011
rhythmic behavior GO:0007622 76 0.011
regulation of cellular localization GO:0060341 136 0.011
cell maturation GO:0048469 144 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
response to hexose GO:0009746 3 0.011
ion transport GO:0006811 145 0.011
imaginal disc derived wing hair organization GO:0035317 45 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
regulation of catalytic activity GO:0050790 185 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
cellular component disassembly GO:0022411 46 0.011
epidermal cell differentiation GO:0009913 51 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
innate immune response activating signal transduction GO:0002758 2 0.011
mrna metabolic process GO:0016071 124 0.011
nuclear division GO:0000280 332 0.011
regulation of immune system process GO:0002682 176 0.011
cellular macromolecule localization GO:0070727 220 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
histoblast morphogenesis GO:0007488 9 0.011
Fly
regulation of catabolic process GO:0009894 170 0.011
establishment of blood nerve barrier GO:0008065 2 0.011
rna splicing GO:0008380 83 0.011
phosphate ion transport GO:0006817 4 0.011
nucleotide metabolic process GO:0009117 161 0.011
positive regulation of developmental process GO:0051094 143 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.010
positive regulation of biosynthetic process GO:0009891 316 0.010
lateral inhibition GO:0046331 206 0.010
apoptotic process GO:0006915 159 0.010
regulation of cellular response to stress GO:0080135 89 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.010
circadian rhythm GO:0007623 105 0.010
regulation of cell proliferation GO:0042127 163 0.010
cellular response to endogenous stimulus GO:0071495 80 0.010
histolysis GO:0007559 102 0.010
regulation of phosphate metabolic process GO:0019220 210 0.010
pigment metabolic process involved in pigmentation GO:0043474 33 0.010

Cyp12a4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
hypertension DOID:10763 0 0.907
artery disease DOID:0050828 0 0.907
disease of anatomical entity DOID:7 0 0.907
vascular disease DOID:178 0 0.907
essential hypertension DOID:10825 0 0.907
cardiovascular system disease DOID:1287 0 0.907
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.013
nervous system disease DOID:863 0 0.012
carbohydrate metabolism disease DOID:0050013 0 0.010
glucose metabolism disease DOID:4194 0 0.010
acquired metabolic disease DOID:0060158 0 0.010