Drosophila melanogaster

55 known processes

CG8878 (Dmel_CG8878)

CG8878 gene product from transcript CG8878-RA

(Aliases: VRK,Dmel\CG8878,BcDNA:LD23371)

CG8878 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule localization GO:0070727 220 0.281
cell division GO:0051301 248 0.238
regulation of cell cycle GO:0051726 291 0.235
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.216
positive regulation of nucleic acid templated transcription GO:1903508 266 0.195
positive regulation of rna biosynthetic process GO:1902680 266 0.187
positive regulation of transcription dna templated GO:0045893 266 0.168
cellular response to dna damage stimulus GO:0006974 223 0.138
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.120
transcription from rna polymerase ii promoter GO:0006366 368 0.109
positive regulation of macromolecule metabolic process GO:0010604 405 0.107
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.099
positive regulation of cellular biosynthetic process GO:0031328 316 0.089
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.085
positive regulation of rna metabolic process GO:0051254 271 0.084
organelle inheritance GO:0048308 2 0.079
Human
cellular protein modification process GO:0006464 438 0.079
Human Mouse Worm Fly
protein localization GO:0008104 284 0.079
establishment of localization in cell GO:0051649 402 0.071
single organism intracellular transport GO:1902582 207 0.070
neurological system process GO:0050877 358 0.063
regulation of cell cycle phase transition GO:1901987 130 0.062
catabolic process GO:0009056 409 0.061
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.060
mitotic cell cycle checkpoint GO:0007093 88 0.060
chromatin organization GO:0006325 207 0.059
Human Fly
vesicle mediated transport GO:0016192 381 0.059
morphogenesis of an epithelium GO:0002009 276 0.058
positive regulation of response to stimulus GO:0048584 323 0.057
cellular protein localization GO:0034613 160 0.055
cell cell signaling involved in cell fate commitment GO:0045168 210 0.053
cellular catabolic process GO:0044248 372 0.050
lateral inhibition GO:0046331 206 0.050
regulation of organelle organization GO:0033043 196 0.047
regulation of catabolic process GO:0009894 170 0.046
positive regulation of gene expression GO:0010628 290 0.046
negative regulation of cell cycle phase transition GO:1901988 103 0.044
regulation of cell proliferation GO:0042127 163 0.043
protein complex assembly GO:0006461 200 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.041
eye development GO:0001654 323 0.040
formation of a compartment boundary GO:0060288 4 0.039
regulation of cell cycle process GO:0010564 181 0.039
regulation of cellular protein metabolic process GO:0032268 243 0.038
negative regulation of gene expression GO:0010629 387 0.038
positive regulation of cellular component organization GO:0051130 156 0.037
single organism behavior GO:0044708 391 0.037
protein modification process GO:0036211 438 0.037
Human Mouse Worm Fly
regulation of protein transport GO:0051223 57 0.036
meiotic nuclear division GO:0007126 151 0.036
Fly
anterior posterior pattern specification GO:0009952 136 0.036
axon guidance GO:0007411 233 0.036
negative regulation of neurotransmitter secretion GO:0046929 2 0.035
tissue morphogenesis GO:0048729 297 0.035
cell proliferation GO:0008283 299 0.034
organic substance transport GO:0071702 257 0.034
death GO:0016265 284 0.034
organic substance catabolic process GO:1901575 308 0.034
chromosome organization GO:0051276 360 0.031
Human Fly
nuclear transport GO:0051169 72 0.029
single organism cellular localization GO:1902580 180 0.029
intracellular transport GO:0046907 228 0.028
maintenance of location GO:0051235 73 0.028
negative regulation of cellular biosynthetic process GO:0031327 277 0.028
regulation of protein metabolic process GO:0051246 256 0.027
regulation of intracellular transport GO:0032386 64 0.026
nucleocytoplasmic transport GO:0006913 72 0.026
regulation of mitotic cell cycle phase transition GO:1901990 130 0.026
cellular protein catabolic process GO:0044257 83 0.026
apoptotic process GO:0006915 159 0.026
regulation of localization GO:0032879 275 0.026
negative regulation of rna metabolic process GO:0051253 251 0.026
positive regulation of biosynthetic process GO:0009891 316 0.025
regulation of mitotic cell cycle GO:0007346 190 0.025
programmed cell death GO:0012501 257 0.024
ras protein signal transduction GO:0007265 88 0.024
positive regulation of neuron projection regeneration GO:0070572 3 0.023
negative regulation of biosynthetic process GO:0009890 277 0.023
negative regulation of mitotic cell cycle GO:0045930 109 0.023
positive regulation of organelle organization GO:0010638 65 0.023
regulation of cellular catabolic process GO:0031329 157 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.022
developmental growth GO:0048589 280 0.022
endocytosis GO:0006897 310 0.022
single organism membrane organization GO:0044802 93 0.022
organonitrogen compound metabolic process GO:1901564 318 0.021
establishment of protein localization GO:0045184 163 0.021
salivary gland morphogenesis GO:0007435 145 0.021
cell death GO:0008219 279 0.021
g2 dna damage checkpoint GO:0031572 69 0.021
sensory organ morphogenesis GO:0090596 260 0.021
regulation of protein catabolic process GO:0042176 55 0.020
negative regulation of cell cycle process GO:0010948 109 0.020
cell migration GO:0016477 238 0.020
embryo development ending in birth or egg hatching GO:0009792 152 0.019
Worm
camera type eye development GO:0043010 4 0.019
regulation of protein modification process GO:0031399 112 0.019
axon development GO:0061564 297 0.018
chromatin silencing GO:0006342 76 0.018
regulation of growth GO:0040008 233 0.018
membrane organization GO:0061024 112 0.018
growth GO:0040007 359 0.018
body morphogenesis GO:0010171 2 0.018
positive regulation of phosphate metabolic process GO:0045937 139 0.018
regulation of transport GO:0051049 181 0.018
regulation of apoptotic process GO:0042981 130 0.017
macromolecule catabolic process GO:0009057 161 0.017
chromatin modification GO:0016568 147 0.017
Human Fly
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
central nervous system development GO:0007417 201 0.017
eye morphogenesis GO:0048592 260 0.017
cellular macromolecule catabolic process GO:0044265 136 0.016
negative regulation of cell cycle GO:0045786 116 0.016
negative regulation of protein binding GO:0032091 1 0.016
regulation of semaphorin plexin signaling pathway GO:2001260 2 0.016
embryonic development via the syncytial blastoderm GO:0001700 148 0.016
cellular response to chemical stimulus GO:0070887 199 0.016
Human Worm
positive regulation of signal transduction GO:0009967 223 0.016
compound eye morphogenesis GO:0001745 249 0.015
nucleosome organization GO:0034728 59 0.015
phagocytosis GO:0006909 215 0.015
response to external biotic stimulus GO:0043207 293 0.015
protein ubiquitination GO:0016567 70 0.015
positive regulation of epidermal growth factor activated receptor activity GO:0045741 1 0.015
positive regulation of cell communication GO:0010647 250 0.015
nitric oxide metabolic process GO:0046209 1 0.015
exocrine system development GO:0035272 162 0.014
modification dependent protein catabolic process GO:0019941 78 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.014
mitotic dna integrity checkpoint GO:0044774 75 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
multi multicellular organism process GO:0044706 123 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
gland development GO:0048732 191 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
regulation of hemocyte proliferation GO:0035206 37 0.014
cytoplasmic transport GO:0016482 130 0.014
proteolysis GO:0006508 192 0.014
apoptotic signaling pathway GO:0097190 27 0.014
protein catabolic process GO:0030163 101 0.014
nitrogen compound transport GO:0071705 85 0.013
establishment of tissue polarity GO:0007164 87 0.013
compound eye development GO:0048749 307 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
regulation of protein processing GO:0070613 32 0.013
phosphorylation GO:0016310 294 0.013
positive regulation of signaling GO:0023056 243 0.013
response to abiotic stimulus GO:0009628 341 0.013
nuclear import GO:0051170 51 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
negative regulation of rna biosynthetic process GO:1902679 240 0.013
protein import GO:0017038 55 0.013
head development GO:0060322 135 0.013
positive regulation of protein metabolic process GO:0051247 128 0.012
regulation of programmed cell death GO:0043067 152 0.012
spindle organization GO:0007051 253 0.012
Fly
learning or memory GO:0007611 141 0.012
hindbrain development GO:0030902 2 0.012
response to other organism GO:0051707 293 0.012
reproductive system development GO:0061458 74 0.012
Worm
dendrite development GO:0016358 204 0.012
embryonic morphogenesis GO:0048598 206 0.012
response to biotic stimulus GO:0009607 294 0.012
protein modification by small protein conjugation GO:0032446 79 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
Worm
regulation of stem cell differentiation GO:2000736 14 0.012
ubiquitin dependent protein catabolic process GO:0006511 78 0.011
multi organism behavior GO:0051705 175 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
regulation of meiosis GO:0040020 3 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
regulation of cell differentiation GO:0045595 302 0.011
humoral immune response GO:0006959 117 0.011
reproductive behavior GO:0019098 122 0.011
aromatic compound catabolic process GO:0019439 166 0.011
stress granule disassembly GO:0035617 1 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
organophosphate metabolic process GO:0019637 195 0.011
protein complex biogenesis GO:0070271 201 0.011
organelle assembly GO:0070925 198 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
positive regulation of protein modification process GO:0031401 58 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.010
sex differentiation GO:0007548 81 0.010
Worm
defense response to bacterium GO:0042742 178 0.010
neuron projection guidance GO:0097485 241 0.010
developmental programmed cell death GO:0010623 138 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
regulation of cell death GO:0010941 173 0.010
amine metabolic process GO:0009308 12 0.010
positive regulation of developmental growth GO:0048639 62 0.010
cellular response to nutrient GO:0031670 1 0.010
regulation of cellular localization GO:0060341 136 0.010
regulation of molecular function GO:0065009 217 0.010
Mouse
organic cyclic compound catabolic process GO:1901361 168 0.010

CG8878 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.020
cancer DOID:162 0 0.013
central nervous system cancer DOID:3620 0 0.013
meningioma DOID:3565 0 0.013
familial meningioma DOID:4586 0 0.013
organ system cancer DOID:0050686 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
nervous system cancer DOID:3093 0 0.013