Drosophila melanogaster

37 known processes

Prp8 (Dmel_CG8877)

pre-mRNA processing factor 8

(Aliases: prp8,Dmel\CG8877,CG8877,E-2e)

Prp8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic cell cycle phase transition GO:0044772 138 0.828
regulation of neurogenesis GO:0050767 158 0.759
larval development GO:0002164 104 0.722
Worm
embryo development ending in birth or egg hatching GO:0009792 152 0.625
Worm
regulation of cell cycle process GO:0010564 181 0.568
negative regulation of developmental process GO:0051093 201 0.496
apoptotic process GO:0006915 159 0.477
rna processing GO:0006396 147 0.440
cellular protein modification process GO:0006464 438 0.416
regulation of cell cycle GO:0051726 291 0.328
regulation of growth GO:0040008 233 0.321
cell cycle phase transition GO:0044770 140 0.303
stem cell maintenance GO:0019827 67 0.295
cell proliferation GO:0008283 299 0.287
regulation of mitotic cell cycle GO:0007346 190 0.282
cell death GO:0008219 279 0.266
regulation of cell differentiation GO:0045595 302 0.262
chromatin organization GO:0006325 207 0.261
protein ubiquitination GO:0016567 70 0.237
chromatin assembly or disassembly GO:0006333 52 0.223
regulation of multicellular organismal development GO:2000026 414 0.222
body morphogenesis GO:0010171 2 0.220
gonad development GO:0008406 50 0.214
Worm
rrna processing GO:0006364 3 0.207
ncrna metabolic process GO:0034660 43 0.206
regulation of meiosis GO:0040020 3 0.205
negative regulation of rna biosynthetic process GO:1902679 240 0.205
organic acid metabolic process GO:0006082 103 0.203
modification dependent macromolecule catabolic process GO:0043632 79 0.202
regulation of programmed cell death GO:0043067 152 0.202
posttranscriptional regulation of gene expression GO:0010608 145 0.198
regulation of developmental growth GO:0048638 174 0.197
chromosome organization GO:0051276 360 0.188
ubiquitin dependent protein catabolic process GO:0006511 78 0.186
gene silencing by rna GO:0031047 57 0.179
catabolic process GO:0009056 409 0.175
regulation of chromatin organization GO:1902275 32 0.170
negative regulation of cell differentiation GO:0045596 143 0.170
multi multicellular organism process GO:0044706 123 0.169
cellular macromolecule catabolic process GO:0044265 136 0.168
determination of adult lifespan GO:0008340 137 0.159
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.152
protein modification by small protein conjugation or removal GO:0070647 106 0.151
meiotic cell cycle GO:0051321 171 0.143
axonogenesis GO:0007409 290 0.137
protein modification process GO:0036211 438 0.134
cellular catabolic process GO:0044248 372 0.131
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.130
regulation of phosphate metabolic process GO:0019220 210 0.122
ncrna processing GO:0034470 30 0.122
regulation of chromosome organization GO:0033044 64 0.120
regulation of response to stress GO:0080134 200 0.119
positive regulation of response to stimulus GO:0048584 323 0.117
response to bacterium GO:0009617 198 0.116
establishment of localization in cell GO:0051649 402 0.113
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.111
mitotic dna damage checkpoint GO:0044773 74 0.105
protein modification by small protein conjugation GO:0032446 79 0.103
positive regulation of phosphorylation GO:0042327 87 0.100
regionalization GO:0003002 416 0.100
programmed cell death GO:0012501 257 0.100
dendrite development GO:0016358 204 0.098
cellular macromolecular complex assembly GO:0034622 153 0.096
Human Yeast
cell cycle checkpoint GO:0000075 95 0.095
chromatin remodeling GO:0006338 72 0.095
transcription from rna polymerase ii promoter GO:0006366 368 0.091
negative regulation of cell cycle phase transition GO:1901988 103 0.089
negative regulation of cell cycle process GO:0010948 109 0.083
endocytosis GO:0006897 310 0.080
Worm
negative regulation of mitotic cell cycle GO:0045930 109 0.079
regulation of neuron projection development GO:0010975 69 0.078
negative regulation of cell cycle GO:0045786 116 0.078
stem cell development GO:0048864 79 0.076
mitotic cell cycle checkpoint GO:0007093 88 0.075
positive regulation of signal transduction GO:0009967 223 0.075
positive regulation of cell communication GO:0010647 250 0.072
ribonucleoprotein complex biogenesis GO:0022613 31 0.070
Human Yeast
regulation of mitotic cell cycle phase transition GO:1901990 130 0.068
intracellular signal transduction GO:0035556 300 0.068
axon development GO:0061564 297 0.067
ribonucleoprotein complex subunit organization GO:0071826 28 0.065
Human Yeast
reproductive system development GO:0061458 74 0.064
Worm
positive regulation of developmental growth GO:0048639 62 0.063
immune system process GO:0002376 347 0.063
multi organism reproductive behavior GO:0044705 121 0.062
positive regulation of signaling GO:0023056 243 0.061
lipid localization GO:0010876 54 0.060
organic substance transport GO:0071702 257 0.060
protein dna complex subunit organization GO:0071824 86 0.060
positive regulation of macromolecule metabolic process GO:0010604 405 0.057
multicellular organismal reproductive behavior GO:0033057 110 0.057
regulation of neuron differentiation GO:0045664 103 0.057
organic substance catabolic process GO:1901575 308 0.056
mitotic g2 m transition checkpoint GO:0044818 70 0.056
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.056
regulation of phosphorylation GO:0042325 147 0.055
nucleocytoplasmic transport GO:0006913 72 0.055
cell division GO:0051301 248 0.055
defense response to bacterium GO:0042742 178 0.054
regulation of mrna metabolic process GO:1903311 72 0.054
rna splicing via transesterification reactions GO:0000375 73 0.053
reproductive behavior GO:0019098 122 0.053
response to oxygen containing compound GO:1901700 200 0.052
regulation of rna splicing GO:0043484 69 0.052
aging GO:0007568 143 0.051
nuclear transport GO:0051169 72 0.049
regulation of cytoplasmic transport GO:1903649 47 0.049
positive regulation of multicellular organism growth GO:0040018 21 0.047
regulation of cell death GO:0010941 173 0.046
regulation of mrna processing GO:0050684 71 0.046
regulation of intracellular signal transduction GO:1902531 236 0.046
enzyme linked receptor protein signaling pathway GO:0007167 179 0.045
phosphorylation GO:0016310 294 0.045
reproductive structure development GO:0048608 74 0.045
Worm
small molecule metabolic process GO:0044281 305 0.045
neuron projection guidance GO:0097485 241 0.044
oviposition GO:0018991 19 0.044
gliogenesis GO:0042063 80 0.043
neuroblast proliferation GO:0007405 74 0.043
growth GO:0040007 359 0.043
regulation of protein metabolic process GO:0051246 256 0.042
regulation of immune system process GO:0002682 176 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.042
negative regulation of neuroblast proliferation GO:0007406 27 0.042
ribonucleoprotein complex assembly GO:0022618 23 0.041
Human Yeast
alternative mrna splicing via spliceosome GO:0000380 60 0.041
g2 dna damage checkpoint GO:0031572 69 0.041
dna integrity checkpoint GO:0031570 81 0.040
positive regulation of phosphate metabolic process GO:0045937 139 0.040
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.040
organelle inheritance GO:0048308 2 0.039
intracellular transport GO:0046907 228 0.039
negative regulation of gene expression GO:0010629 387 0.039
rna splicing GO:0008380 83 0.038
positive regulation of intracellular signal transduction GO:1902533 116 0.038
negative regulation of transcription factor import into nucleus GO:0042992 4 0.038
macromolecule catabolic process GO:0009057 161 0.038
proteolysis GO:0006508 192 0.038
multi organism behavior GO:0051705 175 0.037
histone exchange GO:0043486 21 0.036
response to external biotic stimulus GO:0043207 293 0.036
photoreceptor cell differentiation GO:0046530 170 0.035
response to biotic stimulus GO:0009607 294 0.035
positive regulation of phosphorus metabolic process GO:0010562 139 0.034
regulation of cellular protein metabolic process GO:0032268 243 0.034
carboxylic acid metabolic process GO:0019752 92 0.034
regulation of apoptotic process GO:0042981 130 0.034
cytoplasmic transport GO:0016482 130 0.033
negative regulation of multicellular organismal process GO:0051241 142 0.033
regulation of mrna splicing via spliceosome GO:0048024 64 0.032
receptor mediated endocytosis GO:0006898 21 0.032
Worm
response to organic cyclic compound GO:0014070 89 0.031
maintenance of location GO:0051235 73 0.031
positive regulation of gene expression GO:0010628 290 0.030
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.030
modification dependent protein catabolic process GO:0019941 78 0.030
lipid storage GO:0019915 38 0.029
response to other organism GO:0051707 293 0.029
response to abiotic stimulus GO:0009628 341 0.029
chromatin modification GO:0016568 147 0.028
neuron recognition GO:0008038 101 0.027
immune response GO:0006955 246 0.027
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.027
positive regulation of protein metabolic process GO:0051247 128 0.027
response to organic substance GO:0010033 284 0.027
cellular amino acid metabolic process GO:0006520 61 0.026
atp dependent chromatin remodeling GO:0043044 22 0.026
regulation of meiotic cell cycle GO:0051445 9 0.026
cell motility GO:0048870 251 0.026
Worm
anterior posterior pattern specification GO:0009952 136 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.026
signal transduction by phosphorylation GO:0023014 107 0.025
regulation of organelle organization GO:0033043 196 0.025
regulation of cell cycle phase transition GO:1901987 130 0.025
single organism nuclear import GO:1902593 51 0.024
regulation of dna templated transcription elongation GO:0032784 17 0.024
positive regulation of growth GO:0045927 75 0.024
mapk cascade GO:0000165 107 0.024
establishment or maintenance of cell polarity GO:0007163 167 0.023
single organism behavior GO:0044708 391 0.023
spindle organization GO:0007051 253 0.022
establishment of rna localization GO:0051236 47 0.022
multicellular organismal aging GO:0010259 140 0.022
single organism catabolic process GO:0044712 228 0.022
vesicle mediated transport GO:0016192 381 0.022
Worm
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.021
cell growth GO:0016049 108 0.021
aromatic compound catabolic process GO:0019439 166 0.020
mrna metabolic process GO:0016071 124 0.020
regulation of phosphorus metabolic process GO:0051174 210 0.020
regulation of nucleocytoplasmic transport GO:0046822 35 0.019
defense response GO:0006952 300 0.019
sex differentiation GO:0007548 81 0.019
Worm
negative regulation of response to stimulus GO:0048585 258 0.019
regulation of small gtpase mediated signal transduction GO:0051056 93 0.019
rna interference GO:0016246 27 0.019
cell migration GO:0016477 238 0.019
Worm
single organism cellular localization GO:1902580 180 0.018
nucleobase containing compound transport GO:0015931 56 0.018
positive regulation of cellular protein metabolic process GO:0032270 118 0.018
protein catabolic process GO:0030163 101 0.017
posttranscriptional gene silencing by rna GO:0035194 45 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
anterior posterior axis specification GO:0009948 109 0.017
negative regulation of neural precursor cell proliferation GO:2000178 27 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
regulation of mitotic sister chromatid separation GO:0010965 28 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.017
mrna splicing via spliceosome GO:0000398 73 0.017
protein localization to nucleus GO:0034504 55 0.016
dna damage checkpoint GO:0000077 78 0.016
dna templated transcription elongation GO:0006354 18 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
organonitrogen compound metabolic process GO:1901564 318 0.016
gene silencing GO:0016458 138 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
positive regulation of rna metabolic process GO:0051254 271 0.015
axon guidance GO:0007411 233 0.015
epithelial cell differentiation GO:0030855 322 0.015
regulation of catabolic process GO:0009894 170 0.015
posttranscriptional gene silencing GO:0016441 46 0.015
innate immune response GO:0045087 144 0.015
mitotic dna integrity checkpoint GO:0044774 75 0.015
macromolecular complex assembly GO:0065003 256 0.014
Human Yeast
regulation of cellular response to stress GO:0080135 89 0.014
regulation of cell division GO:0051302 72 0.014
protein transport GO:0015031 155 0.014
regulation of hemocyte proliferation GO:0035206 37 0.014
genitalia development GO:0048806 26 0.013
Worm
rna transport GO:0050658 46 0.013
positive regulation of mapk cascade GO:0043410 63 0.013
molting cycle GO:0042303 56 0.013
Worm
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
covalent chromatin modification GO:0016569 106 0.013
eye photoreceptor cell differentiation GO:0001754 145 0.012
macromolecule methylation GO:0043414 45 0.012
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.012
establishment of spindle localization GO:0051293 22 0.012
oxoacid metabolic process GO:0043436 103 0.012
intermediate filament based process GO:0045103 1 0.012
development of primary sexual characteristics GO:0045137 50 0.012
Worm
chromatin assembly GO:0031497 48 0.012
single organism biosynthetic process GO:0044711 206 0.012
response to inorganic substance GO:0010035 44 0.012
response to endogenous stimulus GO:0009719 119 0.012
protein import GO:0017038 55 0.012
rna 3 end processing GO:0031123 45 0.011
meiotic nuclear division GO:0007126 151 0.011
salivary gland development GO:0007431 162 0.011
mrna transport GO:0051028 15 0.011
regulation of intracellular transport GO:0032386 64 0.011
cellular protein catabolic process GO:0044257 83 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
positive regulation of transcription factor import into nucleus GO:0042993 19 0.011
positive regulation of mitotic cell cycle GO:0045931 34 0.011
regulation of notch signaling pathway GO:0008593 100 0.011
axis specification GO:0009798 167 0.011
positive regulation of catabolic process GO:0009896 105 0.011
heterocycle catabolic process GO:0046700 166 0.011
regulation of apoptotic cell clearance GO:2000425 2 0.010
muscle structure development GO:0061061 224 0.010
regulation of cellular ketone metabolic process GO:0010565 3 0.010
phagocytosis GO:0006909 215 0.010
meiotic cytokinesis GO:0033206 33 0.010
prostanoid biosynthetic process GO:0046457 1 0.010
establishment of protein localization GO:0045184 163 0.010
organelle assembly GO:0070925 198 0.010
regulation of cell development GO:0060284 215 0.010

Prp8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org