Drosophila melanogaster

5 known processes

Irc (Dmel_CG8913)

Immune-regulated catalase

(Aliases: CG8913,Dmel\CG8913,IRC)

Irc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.997
defense response GO:0006952 300 0.975
antibacterial humoral response GO:0019731 44 0.963
humoral immune response GO:0006959 117 0.961
antifungal humoral response GO:0019732 12 0.959
defense response to bacterium GO:0042742 178 0.938
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.918
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 3 0.869
immune system process GO:0002376 347 0.849
antibacterial peptide production GO:0002778 22 0.842
production of molecular mediator of immune response GO:0002440 46 0.793
immune response GO:0006955 246 0.787
defense response to gram negative bacterium GO:0050829 94 0.732
defense response to fungus GO:0050832 48 0.716
response to biotic stimulus GO:0009607 294 0.709
defense response to other organism GO:0098542 225 0.704
regulation of defense response to bacterium GO:1900424 30 0.703
response to external biotic stimulus GO:0043207 293 0.685
innate immune response GO:0045087 144 0.661
antibacterial peptide biosynthetic process GO:0002780 22 0.646
antimicrobial humoral response GO:0019730 99 0.612
antimicrobial peptide biosynthetic process GO:0002777 38 0.607
regulation of melanization defense response GO:0035007 6 0.604
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.585
response to other organism GO:0051707 293 0.582
secondary metabolic process GO:0019748 75 0.556
Fly
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.537
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.533
pattern recognition receptor signaling pathway GO:0002221 2 0.494
melanization defense response GO:0035006 45 0.490
glycosaminoglycan catabolic process GO:0006027 3 0.459
positive regulation of antibacterial peptide production GO:0002803 20 0.454
peptidoglycan recognition protein signaling pathway GO:0061057 16 0.449
positive regulation of humoral immune response GO:0002922 28 0.439
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0006964 12 0.432
positive regulation of cellular amide metabolic process GO:0034250 26 0.428
antimicrobial peptide production GO:0002775 46 0.425
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.421
regulation of cellular amide metabolic process GO:0034248 39 0.420
defense response to gram positive bacterium GO:0050830 41 0.417
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.410
regulation of antibacterial peptide production GO:0002786 22 0.381
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.369
regulation of production of molecular mediator of immune response GO:0002700 44 0.351
immune effector process GO:0002252 98 0.348
positive regulation of response to biotic stimulus GO:0002833 31 0.342
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.326
regulation of defense response GO:0031347 102 0.325
activation of innate immune response GO:0002218 4 0.323
endocytosis GO:0006897 310 0.321
Fly
regulation of response to external stimulus GO:0032101 115 0.320
response to bacterium GO:0009617 198 0.302
positive regulation of immune system process GO:0002684 68 0.297
positive regulation of defense response to bacterium GO:1900426 23 0.289
negative regulation of defense response to bacterium GO:1900425 7 0.272
regulation of antimicrobial humoral response GO:0002759 50 0.266
regulation of immune response GO:0050776 118 0.266
positive regulation of defense response GO:0031349 59 0.250
aminoglycan metabolic process GO:0006022 18 0.240
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.228
positive regulation of antimicrobial peptide production GO:0002225 28 0.223
organonitrogen compound metabolic process GO:1901564 318 0.200
Fly
pigment metabolic process GO:0042440 84 0.195
Fly
cellular response to lipopolysaccharide GO:0071222 3 0.187
positive regulation of antimicrobial humoral response GO:0002760 28 0.179
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.177
vesicle mediated transport GO:0016192 381 0.172
Fly
organonitrogen compound biosynthetic process GO:1901566 117 0.172
peptidoglycan metabolic process GO:0000270 3 0.165
phagocytosis GO:0006909 215 0.163
Fly
regulation of antimicrobial peptide production GO:0002784 44 0.162
regulation of humoral immune response GO:0002920 51 0.153
positive regulation of immune response GO:0050778 63 0.152
peptide biosynthetic process GO:0043043 42 0.150
response to peptidoglycan GO:0032494 2 0.144
positive regulation of response to stimulus GO:0048584 323 0.138
positive regulation of multi organism process GO:0043902 40 0.137
peptide metabolic process GO:0006518 80 0.134
melanin metabolic process GO:0006582 47 0.134
organic hydroxy compound metabolic process GO:1901615 83 0.131
positive regulation of cellular biosynthetic process GO:0031328 316 0.126
positive regulation of biosynthetic process GO:0009891 316 0.123
regulation of immune system process GO:0002682 176 0.121
phenol containing compound metabolic process GO:0018958 57 0.120
organelle fission GO:0048285 340 0.109
negative regulation of defense response GO:0031348 35 0.109
negative regulation of signaling GO:0023057 219 0.103
regulation of secondary metabolic process GO:0043455 7 0.102
response to fungus GO:0009620 50 0.102
positive regulation of response to external stimulus GO:0032103 44 0.100
cellular response to molecule of bacterial origin GO:0071219 3 0.087
taxis GO:0042330 304 0.087
negative regulation of cell communication GO:0010648 223 0.081
cellular response to radiation GO:0071478 52 0.079
negative regulation of response to stimulus GO:0048585 258 0.077
innate immune response activating signal transduction GO:0002758 2 0.076
response to organic substance GO:0010033 284 0.075
aging GO:0007568 143 0.074
appendage morphogenesis GO:0035107 397 0.074
positive regulation of antifungal peptide biosynthetic process GO:0006967 5 0.073
regulation of multi organism process GO:0043900 131 0.070
imaginal disc derived wing morphogenesis GO:0007476 337 0.067
intracellular signal transduction GO:0035556 300 0.066
response to organonitrogen compound GO:0010243 75 0.065
regulation of nervous system development GO:0051960 248 0.064
determination of adult lifespan GO:0008340 137 0.063
antifungal peptide production GO:0002781 7 0.061
meiotic cell cycle GO:0051321 171 0.060
catabolic process GO:0009056 409 0.059
cellular amide metabolic process GO:0043603 80 0.059
imaginal disc derived appendage morphogenesis GO:0035114 395 0.059
mapk cascade GO:0000165 107 0.057
defense response to virus GO:0051607 23 0.056
regulation of immune effector process GO:0002697 52 0.055
post embryonic appendage morphogenesis GO:0035120 385 0.053
negative regulation of cellular metabolic process GO:0031324 382 0.053
regulation of innate immune response GO:0045088 71 0.053
positive regulation of cell communication GO:0010647 250 0.051
response to oxygen containing compound GO:1901700 200 0.050
regionalization GO:0003002 416 0.048
regulation of localization GO:0032879 275 0.048
pigmentation GO:0043473 75 0.047
Fly
regulation of proteolysis GO:0030162 87 0.046
death GO:0016265 284 0.045
Fly
negative regulation of signal transduction GO:0009968 206 0.045
cellular response to chemical stimulus GO:0070887 199 0.044
carbohydrate derivative metabolic process GO:1901135 217 0.044
regulation of response to stress GO:0080134 200 0.042
regulation of cell morphogenesis GO:0022604 163 0.042
acylglycerol metabolic process GO:0006639 12 0.040
chemotaxis GO:0006935 249 0.039
multicellular organismal aging GO:0010259 140 0.038
regulation of catalytic activity GO:0050790 185 0.038
organic substance catabolic process GO:1901575 308 0.038
response to lipopolysaccharide GO:0032496 4 0.037
muscle structure development GO:0061061 224 0.037
cell adhesion GO:0007155 136 0.036
positive regulation of signaling GO:0023056 243 0.036
lateral inhibition GO:0046331 206 0.035
biological adhesion GO:0022610 138 0.034
cellular response to abiotic stimulus GO:0071214 58 0.034
nuclear division GO:0000280 332 0.034
chemosensory behavior GO:0007635 106 0.034
regulation of organelle organization GO:0033043 196 0.033
cellular response to oxygen containing compound GO:1901701 79 0.033
regulation of transport GO:0051049 181 0.033
regulation of response to biotic stimulus GO:0002831 63 0.033
imaginal disc derived appendage development GO:0048737 399 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.032
growth GO:0040007 359 0.032
cellular response to organic substance GO:0071310 132 0.031
stress activated mapk cascade GO:0051403 52 0.031
melanotic encapsulation of foreign target GO:0035011 30 0.030
regulation of molecular function GO:0065009 217 0.030
reactive oxygen species metabolic process GO:0072593 22 0.029
positive regulation of melanization defense response GO:0035008 1 0.029
regulation of intracellular signal transduction GO:1902531 236 0.028
small molecule metabolic process GO:0044281 305 0.028
Fly
regulation of vesicle mediated transport GO:0060627 59 0.028
regulation of cellular component biogenesis GO:0044087 201 0.028
proteolysis GO:0006508 192 0.027
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.027
amide biosynthetic process GO:0043604 42 0.027
regulation of cell shape GO:0008360 113 0.027
dorsal ventral axis specification GO:0009950 66 0.027
meiotic nuclear division GO:0007126 151 0.027
response to abiotic stimulus GO:0009628 341 0.027
response to wounding GO:0009611 94 0.027
regulation of response to wounding GO:1903034 19 0.027
axis specification GO:0009798 167 0.026
regulation of cell differentiation GO:0045595 302 0.026
negative regulation of response to external stimulus GO:0032102 22 0.026
dna metabolic process GO:0006259 227 0.026
response to nitrogen compound GO:1901698 90 0.025
organic substance transport GO:0071702 257 0.025
hemolymph coagulation GO:0042381 10 0.025
epithelial cell migration GO:0010631 148 0.025
macromolecule catabolic process GO:0009057 161 0.024
regulation of hydrolase activity GO:0051336 97 0.024
regulation of mapk cascade GO:0043408 92 0.024
regulation of growth GO:0040008 233 0.024
cell cell signaling involved in cell fate commitment GO:0045168 210 0.023
neuron projection guidance GO:0097485 241 0.023
regulation of phosphate metabolic process GO:0019220 210 0.023
positive regulation of antifungal peptide production GO:0002804 6 0.023
positive regulation of cellular component biogenesis GO:0044089 80 0.022
open tracheal system development GO:0007424 204 0.022
regulation of antifungal peptide production GO:0002788 6 0.022
positive regulation of signal transduction GO:0009967 223 0.022
apoptotic process GO:0006915 159 0.022
dorsal ventral pattern formation GO:0009953 133 0.022
cellular response to biotic stimulus GO:0071216 4 0.021
immune response regulating signaling pathway GO:0002764 2 0.021
wing disc morphogenesis GO:0007472 344 0.021
regulation of cell death GO:0010941 173 0.020
Fly
axon development GO:0061564 297 0.020
cellular homeostasis GO:0019725 80 0.020
actin filament organization GO:0007015 126 0.020
phosphatidylinositol mediated signaling GO:0048015 4 0.020
immune response activating signal transduction GO:0002757 2 0.020
response to radiation GO:0009314 155 0.020
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
neutral lipid metabolic process GO:0006638 12 0.019
protein processing GO:0016485 68 0.019
regulation of multicellular organismal development GO:2000026 414 0.019
olfactory behavior GO:0042048 97 0.019
wound healing GO:0042060 75 0.019
neurotransmitter catabolic process GO:0042135 1 0.019
axon guidance GO:0007411 233 0.019
cellular amine metabolic process GO:0044106 12 0.019
regulation of endopeptidase activity GO:0052548 36 0.019
synaptic transmission GO:0007268 288 0.019
non sensory hair organization GO:0035316 47 0.019
epithelial cell differentiation GO:0030855 322 0.018
cell migration GO:0016477 238 0.018
cellular biogenic amine catabolic process GO:0042402 1 0.017
autophagic cell death GO:0048102 83 0.017
phosphorylation GO:0016310 294 0.017
positive regulation of transport GO:0051050 92 0.017
developmental growth GO:0048589 280 0.016
developmental programmed cell death GO:0010623 138 0.016
negative regulation of intracellular signal transduction GO:1902532 57 0.016
positive regulation of cellular component organization GO:0051130 156 0.016
negative regulation of innate immune response GO:0045824 30 0.016
cellular ketone metabolic process GO:0042180 24 0.016
Fly
cell death GO:0008219 279 0.016
Fly
cellular catabolic process GO:0044248 372 0.016
axonogenesis GO:0007409 290 0.016
regulation of programmed cell death GO:0043067 152 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.016
salivary gland histolysis GO:0035070 88 0.015
negative regulation of proteolysis GO:0045861 31 0.015
glycosaminoglycan metabolic process GO:0030203 11 0.015
localization of cell GO:0051674 257 0.015
salivary gland development GO:0007431 162 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.015
single organism behavior GO:0044708 391 0.015
toll signaling pathway GO:0008063 25 0.015
regulation of antifungal peptide biosynthetic process GO:0002810 5 0.015
secretion by cell GO:0032940 101 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
peptidoglycan catabolic process GO:0009253 3 0.015
positive regulation of innate immune response GO:0045089 38 0.015
epithelial cell development GO:0002064 274 0.015
regulation of cellular localization GO:0060341 136 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
oligosaccharide transport GO:0015772 2 0.014
single organism biosynthetic process GO:0044711 206 0.014
Fly
positive regulation of organelle organization GO:0010638 65 0.014
establishment of localization in cell GO:0051649 402 0.014
exocrine system development GO:0035272 162 0.014
positive regulation of molecular function GO:0044093 136 0.014
regulation of defense response to fungus GO:1900150 6 0.014
phototaxis GO:0042331 21 0.014
regulation of meiosis GO:0040020 3 0.014
nitrogen compound transport GO:0071705 85 0.014
response to nutrient levels GO:0031667 114 0.014
organonitrogen compound catabolic process GO:1901565 128 0.014
detection of external biotic stimulus GO:0098581 2 0.014
regulation of cellular component size GO:0032535 98 0.013
regulation of cell cycle GO:0051726 291 0.013
positive regulation of cell cell adhesion GO:0022409 9 0.013
regulation of cell adhesion GO:0030155 27 0.013
regulation of protein metabolic process GO:0051246 256 0.013
connective tissue development GO:0061448 3 0.013
meiotic cell cycle process GO:1903046 132 0.013
negative regulation of developmental process GO:0051093 201 0.013
mitotic nuclear division GO:0007067 213 0.012
carbohydrate metabolic process GO:0005975 82 0.012
spermatogenesis GO:0007283 200 0.012
response to endogenous stimulus GO:0009719 119 0.012
appendage development GO:0048736 401 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
leg disc morphogenesis GO:0007478 80 0.012
gland development GO:0048732 191 0.011
positive regulation of cell differentiation GO:0045597 64 0.011
positive regulation of cytoskeleton organization GO:0051495 21 0.011
response to hexose GO:0009746 3 0.011
regulation of apoptotic process GO:0042981 130 0.011
salivary gland morphogenesis GO:0007435 145 0.011
aminoglycan catabolic process GO:0006026 6 0.011
regulation of phosphorylation GO:0042325 147 0.011
cell motility GO:0048870 251 0.011
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 4 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
eye development GO:0001654 323 0.011
negative regulation of molecular function GO:0044092 51 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
cell cycle checkpoint GO:0000075 95 0.011
imaginal disc derived leg morphogenesis GO:0007480 80 0.011
dendrite morphogenesis GO:0048813 199 0.011
regulation of hemocyte proliferation GO:0035206 37 0.011
gland morphogenesis GO:0022612 145 0.011
actin filament bundle assembly GO:0051017 26 0.010
developmental maturation GO:0021700 172 0.010
detection of chemical stimulus GO:0009593 93 0.010
cell projection assembly GO:0030031 94 0.010
cellular protein modification process GO:0006464 438 0.010
retina development in camera type eye GO:0060041 4 0.010
cellular ion homeostasis GO:0006873 39 0.010
response to light stimulus GO:0009416 124 0.010
regulation of cell cycle process GO:0010564 181 0.010
morphogenesis of an epithelium GO:0002009 276 0.010

Irc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035