Drosophila melanogaster

0 known processes

Mcr (Dmel_CG7586)

Macroglobulin complement-related

(Aliases: Dmel\CG7586,CG7586,anon-28DE,alpha-2-Mrp)

Mcr biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell junction assembly GO:0034329 42 0.998
regulation of tube architecture open tracheal system GO:0035152 68 0.998
cell cell junction organization GO:0045216 55 0.997
establishment of blood brain barrier GO:0060856 16 0.995
apical junction assembly GO:0043297 32 0.995
open tracheal system development GO:0007424 204 0.994
cell junction organization GO:0034330 57 0.992
respiratory system development GO:0060541 213 0.992
cell cell junction assembly GO:0007043 38 0.989
tissue morphogenesis GO:0048729 297 0.981
embryonic morphogenesis GO:0048598 206 0.948
regulation of tube size open tracheal system GO:0035151 43 0.937
morphogenesis of an epithelium GO:0002009 276 0.930
regulation of tube size GO:0035150 46 0.910
axon development GO:0061564 297 0.890
septate junction assembly GO:0019991 26 0.886
dorsal closure GO:0007391 79 0.881
neuron projection guidance GO:0097485 241 0.819
tube morphogenesis GO:0035239 191 0.817
morphogenesis of embryonic epithelium GO:0016331 94 0.807
extracellular matrix organization GO:0030198 32 0.804
axonogenesis GO:0007409 290 0.778
cell motility GO:0048870 251 0.770
biological adhesion GO:0022610 138 0.761
developmental growth involved in morphogenesis GO:0060560 65 0.728
regulation of anatomical structure morphogenesis GO:0022603 242 0.709
gliogenesis GO:0042063 80 0.708
cell adhesion GO:0007155 136 0.668
glial cell differentiation GO:0010001 35 0.638
immune response GO:0006955 246 0.630
Fly
cell migration GO:0016477 238 0.606
establishment of glial blood brain barrier GO:0060857 14 0.539
axon guidance GO:0007411 233 0.509
epithelial cell differentiation GO:0030855 322 0.502
Mouse
central nervous system development GO:0007417 201 0.494
protein modification process GO:0036211 438 0.489
Mouse
regulation of tube length open tracheal system GO:0035159 24 0.458
regulation of cell differentiation GO:0045595 302 0.446
Mouse
localization of cell GO:0051674 257 0.415
response to biotic stimulus GO:0009607 294 0.399
Fly
defense response GO:0006952 300 0.395
Fly
presynaptic membrane organization GO:0097090 4 0.381
innate immune response GO:0045087 144 0.375
response to organic substance GO:0010033 284 0.344
negative regulation of cell differentiation GO:0045596 143 0.340
regulation of multicellular organismal development GO:2000026 414 0.319
Mouse
maintenance of location GO:0051235 73 0.315
immune system process GO:0002376 347 0.313
Mouse Fly
protein localization GO:0008104 284 0.311
response to other organism GO:0051707 293 0.308
Fly
extracellular structure organization GO:0043062 46 0.294
regulation of cell morphogenesis GO:0022604 163 0.293
tube development GO:0035295 244 0.281
head involution GO:0008258 35 0.277
ameboidal type cell migration GO:0001667 151 0.274
intracellular signal transduction GO:0035556 300 0.257
positive regulation of protein metabolic process GO:0051247 128 0.255
neuron projection extension GO:1990138 32 0.249
glial cell development GO:0021782 27 0.243
ion transport GO:0006811 145 0.235
regulation of anatomical structure size GO:0090066 163 0.234
positive regulation of developmental process GO:0051094 143 0.233
embryonic development via the syncytial blastoderm GO:0001700 148 0.230
protein complex biogenesis GO:0070271 201 0.224
developmental maturation GO:0021700 172 0.223
cellular protein modification process GO:0006464 438 0.222
Mouse
response to wounding GO:0009611 94 0.220
germ cell migration GO:0008354 43 0.220
branching involved in open tracheal system development GO:0060446 45 0.209
meiotic cell cycle GO:0051321 171 0.208
single organism carbohydrate metabolic process GO:0044723 72 0.191
cellular macromolecule localization GO:0070727 220 0.189
regulation of response to external stimulus GO:0032101 115 0.186
striated muscle cell development GO:0055002 50 0.179
chemotaxis GO:0006935 249 0.179
cellular response to oxygen containing compound GO:1901701 79 0.173
trachea development GO:0060438 29 0.168
digestive system development GO:0055123 149 0.165
response to organophosphorus GO:0046683 2 0.164
cell recognition GO:0008037 102 0.163
regulation of defense response GO:0031347 102 0.157
digestive tract development GO:0048565 149 0.155
cation transport GO:0006812 110 0.153
camera type eye development GO:0043010 4 0.148
carbohydrate derivative metabolic process GO:1901135 217 0.144
single organism cellular localization GO:1902580 180 0.143
metal ion transport GO:0030001 74 0.140
ovarian follicle cell development GO:0030707 248 0.136
taxis GO:0042330 304 0.130
ion transmembrane transport GO:0034220 122 0.129
epithelial cell migration GO:0010631 148 0.128
regulation of cellular localization GO:0060341 136 0.126
response to radiation GO:0009314 155 0.125
carbohydrate derivative biosynthetic process GO:1901137 85 0.124
positive regulation of signal transduction GO:0009967 223 0.123
regionalization GO:0003002 416 0.122
regulation of cell development GO:0060284 215 0.121
regulation of cell shape GO:0008360 113 0.121
meiotic cell cycle process GO:1903046 132 0.119
cellular response to chemical stimulus GO:0070887 199 0.118
regulation of immune system process GO:0002682 176 0.116
epithelial cell development GO:0002064 274 0.114
cellular protein localization GO:0034613 160 0.114
striated muscle cell differentiation GO:0051146 90 0.111
response to oxygen containing compound GO:1901700 200 0.108
telencephalon development GO:0021537 2 0.104
cell maturation GO:0048469 144 0.102
single organism behavior GO:0044708 391 0.100
homeostatic process GO:0042592 199 0.100
cellular catabolic process GO:0044248 372 0.097
defense response to other organism GO:0098542 225 0.090
Fly
immune response regulating signaling pathway GO:0002764 2 0.090
skin development GO:0043588 65 0.089
Mouse
protein transport GO:0015031 155 0.088
protein complex assembly GO:0006461 200 0.088
response to organonitrogen compound GO:0010243 75 0.088
regulation of catalytic activity GO:0050790 185 0.087
cellular component disassembly GO:0022411 46 0.086
response to external biotic stimulus GO:0043207 293 0.086
Fly
axis specification GO:0009798 167 0.086
regulation of response to stress GO:0080134 200 0.084
positive regulation of cellular component organization GO:0051130 156 0.084
protein localization to organelle GO:0033365 82 0.083
regulation of cell cell adhesion GO:0022407 21 0.081
protein complex disassembly GO:0043241 36 0.080
positive regulation of defense response GO:0031349 59 0.080
positive regulation of multicellular organismal process GO:0051240 143 0.080
cell adhesion involved in heart morphogenesis GO:0061343 12 0.079
single organismal cell cell adhesion GO:0016337 45 0.079
endocytosis GO:0006897 310 0.078
Fly
positive regulation of signaling GO:0023056 243 0.077
ensheathment of neurons GO:0007272 10 0.077
body morphogenesis GO:0010171 2 0.076
protein import GO:0017038 55 0.075
cell substrate adhesion GO:0031589 10 0.074
single organism nuclear import GO:1902593 51 0.073
neurological system process GO:0050877 358 0.073
regulation of innate immune response GO:0045088 71 0.071
organophosphate metabolic process GO:0019637 195 0.070
imaginal disc derived wing morphogenesis GO:0007476 337 0.069
muscle cell differentiation GO:0042692 103 0.069
response to hormone GO:0009725 45 0.068
regulation of cell adhesion GO:0030155 27 0.066
regulation of axonogenesis GO:0050770 32 0.066
organelle fission GO:0048285 340 0.065
synaptic transmission GO:0007268 288 0.065
response to lipopolysaccharide GO:0032496 4 0.065
cell migration involved in gastrulation GO:0042074 9 0.063
developmental growth GO:0048589 280 0.063
innate immune response in mucosa GO:0002227 2 0.063
branching morphogenesis of an epithelial tube GO:0048754 45 0.063
heart morphogenesis GO:0003007 32 0.062
regulation of actin cytoskeleton organization GO:0032956 42 0.061
positive regulation of phosphate metabolic process GO:0045937 139 0.058
cellular response to organic substance GO:0071310 132 0.058
detection of stimulus involved in sensory perception GO:0050906 92 0.058
response to endogenous stimulus GO:0009719 119 0.058
mesodermal cell migration GO:0008078 7 0.057
cellular response to endogenous stimulus GO:0071495 80 0.057
cell activation GO:0001775 9 0.055
single organism biosynthetic process GO:0044711 206 0.055
regulation of immune response GO:0050776 118 0.055
negative regulation of cell adhesion GO:0007162 9 0.054
morphogenesis of a branching structure GO:0001763 45 0.053
embryo development ending in birth or egg hatching GO:0009792 152 0.053
carbohydrate metabolic process GO:0005975 82 0.053
regulation of transport GO:0051049 181 0.052
cellular component assembly involved in morphogenesis GO:0010927 151 0.052
regulation of protein metabolic process GO:0051246 256 0.052
Mouse
regulation of cellular response to stress GO:0080135 89 0.052
negative regulation of multicellular organismal process GO:0051241 142 0.051
brain development GO:0007420 120 0.051
forebrain development GO:0030900 2 0.051
response to abiotic stimulus GO:0009628 341 0.051
adult locomotory behavior GO:0008344 76 0.050
wing disc morphogenesis GO:0007472 344 0.050
columnar cuboidal epithelial cell development GO:0002066 249 0.049
protein modification by small protein conjugation or removal GO:0070647 106 0.049
transmembrane transport GO:0055085 139 0.049
gastrulation GO:0007369 70 0.048
epithelial cell morphogenesis involved in gastrulation GO:0003381 7 0.048
nuclear transport GO:0051169 72 0.048
axonal fasciculation GO:0007413 12 0.048
axon ensheathment GO:0008366 10 0.048
negative regulation of developmental growth GO:0048640 64 0.047
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.046
response to organic cyclic compound GO:0014070 89 0.046
post embryonic appendage morphogenesis GO:0035120 385 0.045
learning GO:0007612 75 0.044
cation homeostasis GO:0055080 51 0.044
protein localization to nucleus GO:0034504 55 0.044
establishment of protein localization GO:0045184 163 0.044
cellular response to hormone stimulus GO:0032870 44 0.042
wound healing GO:0042060 75 0.042
positive regulation of immune response GO:0050778 63 0.042
oocyte axis specification GO:0007309 108 0.041
regulation of mapk cascade GO:0043408 92 0.041
positive regulation of transport GO:0051050 92 0.041
regulation of transferase activity GO:0051338 58 0.040
negative regulation of signal transduction GO:0009968 206 0.040
cellular response to peptide GO:1901653 28 0.039
negative regulation of cell development GO:0010721 62 0.039
tissue migration GO:0090130 155 0.037
wnt signaling pathway GO:0016055 98 0.036
positive regulation of developmental growth GO:0048639 62 0.036
protein targeting to nucleus GO:0044744 51 0.036
synaptic target recognition GO:0008039 45 0.036
protein phosphorylation GO:0006468 169 0.035
Mouse
epidermis development GO:0008544 65 0.035
Mouse
circulatory system development GO:0072359 82 0.035
negative regulation of response to stimulus GO:0048585 258 0.035
epithelium migration GO:0090132 148 0.034
regulation of tube diameter GO:0035296 14 0.034
actin cytoskeleton organization GO:0030036 206 0.033
lateral inhibition GO:0046331 206 0.033
positive regulation of cell communication GO:0010647 250 0.033
regulation of localization GO:0032879 275 0.033
response to nitrogen compound GO:1901698 90 0.033
response to light stimulus GO:0009416 124 0.033
negative regulation of developmental process GO:0051093 201 0.033
regulation of cell projection organization GO:0031344 92 0.033
reproductive system development GO:0061458 74 0.033
regulation of nervous system development GO:0051960 248 0.032
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.032
morphogenesis of a branching epithelium GO:0061138 45 0.032
retinal ganglion cell axon guidance GO:0031290 12 0.031
heart development GO:0007507 82 0.031
regulation of cell size GO:0008361 63 0.031
gland development GO:0048732 191 0.031
establishment of protein localization to organelle GO:0072594 62 0.030
cellular response to organonitrogen compound GO:0071417 36 0.030
phosphorylation GO:0016310 294 0.030
Mouse
golgi organization GO:0007030 66 0.030
positive regulation of molecular function GO:0044093 136 0.030
negative regulation of cellular component organization GO:0051129 108 0.030
mesoderm development GO:0007498 78 0.030
single organism cell adhesion GO:0098602 47 0.029
positive regulation of response to stimulus GO:0048584 323 0.029
cellular protein complex disassembly GO:0043624 35 0.029
regulation of multi organism process GO:0043900 131 0.029
gastrulation with mouth forming first GO:0001703 36 0.028
cuticle development GO:0042335 86 0.028
hemopoiesis GO:0030097 46 0.027
Mouse
nucleotide metabolic process GO:0009117 161 0.027
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.027
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.027
glycoprotein biosynthetic process GO:0009101 41 0.026
appendage development GO:0048736 401 0.026
digestive tract morphogenesis GO:0048546 127 0.026
retina development in camera type eye GO:0060041 4 0.026
positive regulation of innate immune response GO:0045089 38 0.025
growth GO:0040007 359 0.025
regulation of intracellular protein transport GO:0033157 46 0.025
genitalia morphogenesis GO:0035112 16 0.025
larval development GO:0002164 104 0.025
regulation of intracellular signal transduction GO:1902531 236 0.025
positive regulation of catalytic activity GO:0043085 118 0.025
mapk cascade GO:0000165 107 0.024
endodermal cell differentiation GO:0035987 3 0.024
macromolecular complex assembly GO:0065003 256 0.024
regulation of response to biotic stimulus GO:0002831 63 0.024
oocyte development GO:0048599 124 0.023
endodermal cell fate commitment GO:0001711 3 0.023
innate immune response activating signal transduction GO:0002758 2 0.023
regulation of molecular function GO:0065009 217 0.023
neuron recognition GO:0008038 101 0.022
carbohydrate derivative catabolic process GO:1901136 118 0.022
apical constriction GO:0003383 18 0.022
signal transduction by phosphorylation GO:0023014 107 0.022
zinc ion transport GO:0006829 5 0.021
regulation of phosphorylation GO:0042325 147 0.021
Mouse
cell cell signaling involved in cell fate commitment GO:0045168 210 0.021
membrane organization GO:0061024 112 0.021
sensory perception of mechanical stimulus GO:0050954 72 0.021
imaginal disc derived appendage development GO:0048737 399 0.021
regulation of protein modification process GO:0031399 112 0.021
Mouse
positive regulation of immune system process GO:0002684 68 0.021
photoreceptor cell development GO:0042461 96 0.021
transmission of nerve impulse GO:0019226 12 0.020
heparan sulfate proteoglycan biosynthetic process GO:0015012 10 0.020
nuclear import GO:0051170 51 0.020
negative regulation of multi organism process GO:0043901 29 0.020
interspecies interaction between organisms GO:0044419 16 0.020
establishment of cell polarity GO:0030010 40 0.020
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 15 0.020
protein modification by small protein conjugation GO:0032446 79 0.020
organic substance transport GO:0071702 257 0.019
cell growth GO:0016049 108 0.018
exocrine system development GO:0035272 162 0.018
cell adhesion mediated by integrin GO:0033627 12 0.018
membrane biogenesis GO:0044091 8 0.018
adult behavior GO:0030534 137 0.018
hindbrain development GO:0030902 2 0.018
response to virus GO:0009615 28 0.018
molting cycle GO:0042303 56 0.018
Mouse
determination of adult lifespan GO:0008340 137 0.018
positive regulation of cell differentiation GO:0045597 64 0.018
positive regulation of axon extension GO:0045773 2 0.018
intracellular transport GO:0046907 228 0.018
action potential GO:0001508 13 0.017
lipid localization GO:0010876 54 0.017
mesenchymal cell development GO:0014031 1 0.017
axon extension GO:0048675 32 0.017
regulation of neuron projection development GO:0010975 69 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
Mouse
positive regulation of protein localization to nucleus GO:1900182 21 0.017
instar larval development GO:0002168 55 0.017
organic hydroxy compound metabolic process GO:1901615 83 0.017
regulation of dendrite morphogenesis GO:0048814 28 0.016
cellular response to lipopolysaccharide GO:0071222 3 0.016
detection of light stimulus GO:0009583 58 0.016
neuronal action potential GO:0019228 10 0.016
catabolic process GO:0009056 409 0.016
regulation of tube diameter open tracheal system GO:0035158 11 0.016
regulation of hydrolase activity GO:0051336 97 0.016
inorganic ion transmembrane transport GO:0098660 73 0.016
adherens junction organization GO:0034332 27 0.016
detection of stimulus GO:0051606 156 0.016
immune response activating signal transduction GO:0002757 2 0.015
locomotory behavior GO:0007626 176 0.015
positive regulation of phosphorylation GO:0042327 87 0.015
negative regulation of rna metabolic process GO:0051253 251 0.015
positive regulation of jun kinase activity GO:0043507 4 0.015
mesenchyme development GO:0060485 9 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
response to nutrient levels GO:0031667 114 0.015
cellular response to abiotic stimulus GO:0071214 58 0.015
axis elongation GO:0003401 3 0.015
cellular response to nitrogen compound GO:1901699 51 0.015
negative regulation of response to external stimulus GO:0032102 22 0.015
intracellular protein transport GO:0006886 104 0.015
segmentation GO:0035282 207 0.015
macromolecular complex disassembly GO:0032984 37 0.014
regulation of cell motility GO:2000145 23 0.014
regulation of hemocyte proliferation GO:0035206 37 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.014
tube formation GO:0035148 21 0.014
development of primary sexual characteristics GO:0045137 50 0.014
cellular amine metabolic process GO:0044106 12 0.014
stem cell differentiation GO:0048863 117 0.014
sex differentiation GO:0007548 81 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
regulation of multicellular organism growth GO:0040014 40 0.014
chitin based cuticle development GO:0040003 49 0.014
actin mediated cell contraction GO:0070252 21 0.014
imaginal disc growth GO:0007446 37 0.014
cellular response to lipid GO:0071396 20 0.014
positive regulation of cellular component biogenesis GO:0044089 80 0.014
regulation of cellular component size GO:0032535 98 0.014
nuclear division GO:0000280 332 0.013
multicellular organism growth GO:0035264 46 0.013
cardiovascular system development GO:0072358 82 0.013
multicellular organismal signaling GO:0035637 12 0.013
negative regulation of phosphate metabolic process GO:0045936 45 0.013
Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.013
developmental cell growth GO:0048588 52 0.013
regulation of cell substrate adhesion GO:0010810 2 0.013
regulation of protein targeting GO:1903533 29 0.013
organelle localization GO:0051640 148 0.013
response to axon injury GO:0048678 12 0.012
mitochondrial membrane organization GO:0007006 3 0.012
male genitalia development GO:0030539 19 0.012
single organism intracellular transport GO:1902582 207 0.012
ras protein signal transduction GO:0007265 88 0.012
salivary gland development GO:0007431 162 0.012
cellular response to organic cyclic compound GO:0071407 32 0.012
formation of primary germ layer GO:0001704 24 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
Mouse
establishment or maintenance of cell polarity GO:0007163 167 0.012
regulation of developmental growth GO:0048638 174 0.012
synapse assembly GO:0007416 143 0.012
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.012
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.012
blastoderm segmentation GO:0007350 159 0.012
negative regulation of signaling GO:0023057 219 0.012
sarcomere organization GO:0045214 26 0.012
epithelial cell migration open tracheal system GO:0007427 32 0.012
social behavior GO:0035176 4 0.012
response to lipid GO:0033993 38 0.011
nephron development GO:0072006 3 0.011
regulation of embryonic cell shape GO:0016476 30 0.011
regulation of protein localization GO:0032880 76 0.011
microtubule based movement GO:0007018 51 0.011
regulation of cytoplasmic transport GO:1903649 47 0.011
activation of innate immune response GO:0002218 4 0.011
positive regulation of growth GO:0045927 75 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
cytoplasmic transport GO:0016482 130 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
regulation of protein complex assembly GO:0043254 42 0.011
chemosensory behavior GO:0007635 106 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.011
response to extracellular stimulus GO:0009991 116 0.011
tissue homeostasis GO:0001894 36 0.011
negative regulation of cell communication GO:0010648 223 0.011
nucleocytoplasmic transport GO:0006913 72 0.011
basement membrane organization GO:0071711 10 0.011
regulation of actin polymerization or depolymerization GO:0008064 27 0.010
regulation of protein import into nucleus GO:0042306 28 0.010
positive regulation of intracellular protein transport GO:0090316 30 0.010
antimicrobial humoral response GO:0019730 99 0.010
Fly
positive regulation of intracellular signal transduction GO:1902533 116 0.010
response to alcohol GO:0097305 95 0.010
regulation of neuron differentiation GO:0045664 103 0.010
vesicle mediated transport GO:0016192 381 0.010
Fly
cellular protein complex assembly GO:0043623 71 0.010
positive regulation of protein modification process GO:0031401 58 0.010
oocyte construction GO:0007308 112 0.010
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.010
regulation of protein phosphorylation GO:0001932 64 0.010
Mouse

Mcr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.086
benign neoplasm DOID:0060072 0 0.014
disease of cellular proliferation DOID:14566 0 0.014