Drosophila melanogaster

18 known processes

D2R (Dmel_CG33517)

Dopamine 2-like receptor

(Aliases: CG33517,anon-WO0170980.32,DD2R,CG9569,Dmel\CG33517,CG17004,anon-WO0170980.31,anon-WO0170980.130,anon-WO0170980.131,Dop2R)

D2R biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
feeding behavior GO:0007631 50 0.485
Mouse
detection of chemical stimulus GO:0009593 93 0.215
single organism behavior GO:0044708 391 0.192
Human Mouse Rat
g protein coupled receptor signaling pathway GO:0007186 136 0.164
phenol containing compound metabolic process GO:0018958 57 0.149
Mouse
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.124
chemosensory behavior GO:0007635 106 0.121
Rat
positive regulation of gene expression GO:0010628 290 0.120
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.093
Rat
response to alkaloid GO:0043279 26 0.088
Human Mouse Rat
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.082
Human Rat
organonitrogen compound metabolic process GO:1901564 318 0.081
Human Mouse Rat
detection of stimulus GO:0051606 156 0.074
male mating behavior GO:0060179 70 0.070
defense response GO:0006952 300 0.069
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.061
Rat
sensory perception of chemical stimulus GO:0007606 116 0.061
Mouse
defense response to bacterium GO:0042742 178 0.061
response to insecticide GO:0017085 14 0.058
negative regulation of cellular metabolic process GO:0031324 382 0.057
Human Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.057
Human Rat
positive regulation of cellular biosynthetic process GO:0031328 316 0.056
Rat
positive regulation of rna metabolic process GO:0051254 271 0.055
Rat
positive regulation of transcription dna templated GO:0045893 266 0.055
Rat
positive regulation of biosynthetic process GO:0009891 316 0.054
Rat
response to organic substance GO:0010033 284 0.053
Human Mouse Rat
negative regulation of gene expression GO:0010629 387 0.052
Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.051
Rat
response to other organism GO:0051707 293 0.051
defense response to other organism GO:0098542 225 0.049
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.048
pigment metabolic process GO:0042440 84 0.048
multi organism reproductive behavior GO:0044705 121 0.047
positive regulation of rna biosynthetic process GO:1902680 266 0.047
Rat
carbohydrate derivative metabolic process GO:1901135 217 0.046
Human Rat
negative regulation of camp metabolic process GO:0030815 3 0.045
Human Rat
regulation of developmental growth GO:0048638 174 0.045
Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.045
Rat
response to external biotic stimulus GO:0043207 293 0.045
regulation of cell size GO:0008361 63 0.044
anatomical structure homeostasis GO:0060249 97 0.044
response to biotic stimulus GO:0009607 294 0.043
melanization defense response GO:0035006 45 0.042
response to radiation GO:0009314 155 0.042
Mouse Rat
negative regulation of biosynthetic process GO:0009890 277 0.041
Human Rat
nucleotide metabolic process GO:0009117 161 0.041
Human Rat
regulation of anatomical structure morphogenesis GO:0022603 242 0.040
positive regulation of macromolecule metabolic process GO:0010604 405 0.039
Human Rat
epithelial cell development GO:0002064 274 0.037
neurological system process GO:0050877 358 0.037
Human Mouse Rat
innate immune response GO:0045087 144 0.037
regulation of behavior GO:0050795 75 0.036
Rat
melanin metabolic process GO:0006582 47 0.036
immune response GO:0006955 246 0.036
immune system process GO:0002376 347 0.033
response to monosaccharide GO:0034284 4 0.032
circadian rhythm GO:0007623 105 0.032
Mouse Rat
protein modification process GO:0036211 438 0.032
Human Rat
developmental maturation GO:0021700 172 0.031
compound eye morphogenesis GO:0001745 249 0.031
heart process GO:0003015 37 0.031
Mouse
regulation of camp biosynthetic process GO:0030817 12 0.030
Human Rat
ribonucleotide metabolic process GO:0009259 145 0.030
Human Rat
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 10 0.030
Human Mouse
regulation of growth GO:0040008 233 0.030
Mouse
sensory perception GO:0007600 196 0.029
Mouse
adult behavior GO:0030534 137 0.029
Human Mouse Rat
sensory perception of smell GO:0007608 80 0.029
Mouse
lateral inhibition GO:0046331 206 0.029
purine containing compound biosynthetic process GO:0072522 30 0.028
Human Rat
carbohydrate derivative biosynthetic process GO:1901137 85 0.027
Human Rat
regionalization GO:0003002 416 0.027
macromolecular complex assembly GO:0065003 256 0.027
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 17 0.027
Human Mouse Rat
response to light stimulus GO:0009416 124 0.026
Mouse Rat
negative regulation of nucleic acid templated transcription GO:1903507 240 0.026
Rat
cellular protein modification process GO:0006464 438 0.026
Human Rat
adult feeding behavior GO:0008343 13 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.026
Rat
epithelial cell differentiation GO:0030855 322 0.026
cell death GO:0008219 279 0.025
negative regulation of rna metabolic process GO:0051253 251 0.025
Rat
growth GO:0040007 359 0.025
Mouse
columnar cuboidal epithelial cell development GO:0002066 249 0.025
response to extracellular stimulus GO:0009991 116 0.025
detection of light stimulus GO:0009583 58 0.025
nucleobase containing small molecule metabolic process GO:0055086 174 0.025
Human Rat
negative regulation of rna biosynthetic process GO:1902679 240 0.024
Rat
response to bacterium GO:0009617 198 0.024
purine nucleotide metabolic process GO:0006163 146 0.024
Human Rat
post embryonic appendage morphogenesis GO:0035120 385 0.023
purine ribonucleotide metabolic process GO:0009150 145 0.023
Human Rat
multi organism behavior GO:0051705 175 0.023
positive regulation of nucleic acid templated transcription GO:1903508 266 0.023
Rat
dna metabolic process GO:0006259 227 0.023
homeostatic process GO:0042592 199 0.023
Human Mouse Rat
oocyte differentiation GO:0009994 145 0.023
larval behavior GO:0030537 42 0.023
telencephalon development GO:0021537 2 0.023
Mouse Rat
regulation of nervous system development GO:0051960 248 0.022
Mouse
tube morphogenesis GO:0035239 191 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.022
Rat
ribose phosphate metabolic process GO:0019693 145 0.022
Human Rat
death GO:0016265 284 0.021
sensory perception of taste GO:0050909 25 0.021
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.021
Human Mouse Rat
cellular response to carbohydrate stimulus GO:0071322 4 0.021
regulation of anatomical structure size GO:0090066 163 0.021
cell cell signaling involved in cell fate commitment GO:0045168 210 0.021
chromosome organization GO:0051276 360 0.021
protein complex assembly GO:0006461 200 0.021
compound eye development GO:0048749 307 0.021
defense response to gram negative bacterium GO:0050829 94 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.020
Rat
regulation of nucleotide biosynthetic process GO:0030808 14 0.020
Human Rat
forebrain development GO:0030900 2 0.019
Mouse Rat
regulation of protein metabolic process GO:0051246 256 0.019
Human Rat
cellular ketone metabolic process GO:0042180 24 0.019
response to toxic substance GO:0009636 22 0.019
Rat
oocyte development GO:0048599 124 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.018
Rat
chromatin organization GO:0006325 207 0.018
positive regulation of developmental process GO:0051094 143 0.018
Mouse
ovarian follicle cell development GO:0030707 248 0.018
purine containing compound metabolic process GO:0072521 155 0.018
Human Rat
covalent chromatin modification GO:0016569 106 0.018
negative regulation of signal transduction GO:0009968 206 0.018
Human Mouse Rat
eye photoreceptor cell differentiation GO:0001754 145 0.018
regulation of cell cycle GO:0051726 291 0.018
Human Rat
carboxylic acid metabolic process GO:0019752 92 0.018
organic hydroxy compound metabolic process GO:1901615 83 0.018
Mouse
organic substance catabolic process GO:1901575 308 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.018
Human Rat
appendage development GO:0048736 401 0.018
enzyme linked receptor protein signaling pathway GO:0007167 179 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
Mouse
leg disc development GO:0035218 92 0.017
regulation of organelle organization GO:0033043 196 0.017
Rat
intracellular signal transduction GO:0035556 300 0.017
Human Mouse Rat
regulation of mitotic cell cycle GO:0007346 190 0.017
Rat
digestive tract morphogenesis GO:0048546 127 0.017
organic substance transport GO:0071702 257 0.017
Human Mouse Rat
regulation of cell proliferation GO:0042127 163 0.017
Mouse Rat
male gamete generation GO:0048232 201 0.017
eggshell formation GO:0030703 105 0.016
response to nitrogen compound GO:1901698 90 0.016
Human Mouse Rat
regulation of cell death GO:0010941 173 0.016
salivary gland development GO:0007431 162 0.016
spermatogenesis GO:0007283 200 0.016
small molecule metabolic process GO:0044281 305 0.016
Human Rat
appendage morphogenesis GO:0035107 397 0.016
phototaxis GO:0042331 21 0.016
proteolysis GO:0006508 192 0.016
organic acid metabolic process GO:0006082 103 0.015
regulation of multicellular organismal development GO:2000026 414 0.015
Mouse
regulation of purine nucleotide biosynthetic process GO:1900371 14 0.015
Human Rat
positive regulation of cell proliferation GO:0008284 47 0.015
Mouse Rat
catabolic process GO:0009056 409 0.015
protein localization GO:0008104 284 0.015
Human Mouse
photoreceptor cell differentiation GO:0046530 170 0.015
oxoacid metabolic process GO:0043436 103 0.015
cyclic purine nucleotide metabolic process GO:0052652 25 0.015
Human Rat
camp biosynthetic process GO:0006171 17 0.015
Human Rat
regulation of molecular function GO:0065009 217 0.015
Human Rat
regulation of nucleotide metabolic process GO:0006140 62 0.014
Human Rat
digestive system development GO:0055123 149 0.014
wing disc morphogenesis GO:0007472 344 0.014
cell maturation GO:0048469 144 0.014
response to temperature stimulus GO:0009266 106 0.014
taxis GO:0042330 304 0.014
organophosphate metabolic process GO:0019637 195 0.014
Human Rat
sensory organ morphogenesis GO:0090596 260 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
Human Rat
regulation of cellular component size GO:0032535 98 0.014
regulation of catabolic process GO:0009894 170 0.014
endocytosis GO:0006897 310 0.014
Human Rat
response to organonitrogen compound GO:0010243 75 0.014
Human Mouse Rat
phototransduction GO:0007602 52 0.014
epithelium migration GO:0090132 148 0.014
cellular catabolic process GO:0044248 372 0.014
cellular chemical homeostasis GO:0055082 40 0.013
Human Rat
negative regulation of cellular component organization GO:0051129 108 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
chorion containing eggshell formation GO:0007304 105 0.013
imaginal disc derived appendage development GO:0048737 399 0.013
regulation of immune system process GO:0002682 176 0.013
regulation of gene silencing GO:0060968 63 0.013
cellular homeostasis GO:0019725 80 0.013
Human Rat
regulation of defense response GO:0031347 102 0.013
detection of stimulus involved in sensory perception GO:0050906 92 0.013
protein complex biogenesis GO:0070271 201 0.013
regulation of response to external stimulus GO:0032101 115 0.013
Human Mouse
regulation of phosphate metabolic process GO:0019220 210 0.013
Human Rat
eye development GO:0001654 323 0.013
Rat
cell division GO:0051301 248 0.013
Human Rat
cellular amino acid metabolic process GO:0006520 61 0.013
camera type eye development GO:0043010 4 0.013
Rat
rhythmic process GO:0048511 106 0.013
Mouse Rat
retina development in camera type eye GO:0060041 4 0.013
Rat
regulation of response to stress GO:0080134 200 0.012
rna processing GO:0006396 147 0.012
regulation of cell differentiation GO:0045595 302 0.012
Mouse
ion homeostasis GO:0050801 55 0.012
Human Mouse Rat
negative regulation of cell size GO:0045792 19 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
Human Rat
regulation of organ growth GO:0046620 42 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
Human Rat
leg disc morphogenesis GO:0007478 80 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
regulation of cell shape GO:0008360 113 0.012
kidney development GO:0001822 3 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
response to abiotic stimulus GO:0009628 341 0.012
Mouse Rat
male courtship behavior tapping to detect pheromone GO:0016544 1 0.012
response to alcohol GO:0097305 95 0.012
Mouse Rat
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
Human Rat
antimicrobial humoral response GO:0019730 99 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
phagocytosis GO:0006909 215 0.011
single organism biosynthetic process GO:0044711 206 0.011
Human Rat
positive regulation of cell migration GO:0030335 2 0.011
regulation of programmed cell death GO:0043067 152 0.011
single organism cellular localization GO:1902580 180 0.011
apoptotic process GO:0006915 159 0.011
imaginal disc pattern formation GO:0007447 91 0.011
establishment of protein localization GO:0045184 163 0.011
Human
phosphorylation GO:0016310 294 0.011
Human Rat
ameboidal type cell migration GO:0001667 151 0.011
developmental growth GO:0048589 280 0.011
Mouse
negative regulation of cell death GO:0060548 81 0.011
monocarboxylic acid transport GO:0015718 3 0.011
Human
regulation of cell fate specification GO:0042659 27 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
Mouse Rat
embryonic morphogenesis GO:0048598 206 0.011
cyclic nucleotide biosynthetic process GO:0009190 25 0.011
Human Rat
mitotic spindle organization GO:0007052 220 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
Rat
reproductive behavior GO:0019098 122 0.011
chromatin modification GO:0016568 147 0.010
positive regulation of developmental growth GO:0048639 62 0.010
Mouse
positive regulation of signal transduction GO:0009967 223 0.010
Human Mouse Rat
regulation of response to wounding GO:1903034 19 0.010
neuron projection guidance GO:0097485 241 0.010
protein heterooligomerization GO:0051291 4 0.010
response to endogenous stimulus GO:0009719 119 0.010
Human Mouse Rat
regulation of intracellular signal transduction GO:1902531 236 0.010
Human Mouse Rat
eye morphogenesis GO:0048592 260 0.010
digestive tract development GO:0048565 149 0.010
positive regulation of cell motility GO:2000147 3 0.010
stem cell differentiation GO:0048863 117 0.010
aromatic compound catabolic process GO:0019439 166 0.010

D2R disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
musculoskeletal system disease DOID:17 0 0.015
nervous system disease DOID:863 0 0.014
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012