Drosophila melanogaster

63 known processes

MED28 (Dmel_CG5121)

Mediator complex subunit 28

(Aliases: Med28,dMED23,Med23,CG5121,BcDNA:GM31575,Dmel\CG5121)

MED28 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription from rna polymerase ii promoter GO:0006366 368 0.511
negative regulation of rna metabolic process GO:0051253 251 0.416
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.257
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.251
negative regulation of gene expression GO:0010629 387 0.220
negative regulation of biosynthetic process GO:0009890 277 0.216
negative regulation of cellular biosynthetic process GO:0031327 277 0.185
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.183
negative regulation of nucleic acid templated transcription GO:1903507 240 0.175
negative regulation of rna biosynthetic process GO:1902679 240 0.168
cell cycle checkpoint GO:0000075 95 0.118
regulation of cell cycle process GO:0010564 181 0.104
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.076
negative regulation of cellular metabolic process GO:0031324 382 0.076
negative regulation of transcription dna templated GO:0045892 237 0.066
regulation of gene expression epigenetic GO:0040029 128 0.061
endomembrane system organization GO:0010256 119 0.058
trna transcription from rna polymerase iii promoter GO:0042797 1 0.057
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.054
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.051
positive regulation of transcription dna templated GO:0045893 266 0.048
meiotic nuclear division GO:0007126 151 0.048
positive regulation of cellular component organization GO:0051130 156 0.047
regulation of organelle organization GO:0033043 196 0.046
gene silencing GO:0016458 138 0.045
positive regulation of macromolecule metabolic process GO:0010604 405 0.045
regulation of meiosis GO:0040020 3 0.044
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.039
protein localization GO:0008104 284 0.037
macromolecular complex assembly GO:0065003 256 0.036
carbohydrate derivative metabolic process GO:1901135 217 0.036
positive regulation of gene expression GO:0010628 290 0.035
hatching GO:0035188 4 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.035
mitotic g2 dna damage checkpoint GO:0007095 69 0.033
meiotic cell cycle GO:0051321 171 0.032
meiotic cell cycle process GO:1903046 132 0.031
positive regulation of nucleic acid templated transcription GO:1903508 266 0.031
secretion by cell GO:0032940 101 0.031
negative regulation of gene expression epigenetic GO:0045814 77 0.031
establishment of localization in cell GO:0051649 402 0.030
rna processing GO:0006396 147 0.029
organic substance catabolic process GO:1901575 308 0.029
ribonucleoprotein complex assembly GO:0022618 23 0.027
negative regulation of cell cycle phase transition GO:1901988 103 0.027
nucleobase containing small molecule metabolic process GO:0055086 174 0.027
cellular nitrogen compound catabolic process GO:0044270 165 0.025
response to other organism GO:0051707 293 0.024
regulation of gene silencing GO:0060968 63 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.023
organic cyclic compound catabolic process GO:1901361 168 0.023
rna interference GO:0016246 27 0.022
cellular catabolic process GO:0044248 372 0.021
mitotic g2 m transition checkpoint GO:0044818 70 0.021
mrna processing GO:0006397 104 0.021
nuclear division GO:0000280 332 0.021
positive regulation of rna metabolic process GO:0051254 271 0.019
dna metabolic process GO:0006259 227 0.019
regulation of cellular component biogenesis GO:0044087 201 0.019
positive regulation of cell communication GO:0010647 250 0.019
regulation of chromatin organization GO:1902275 32 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.018
heterochromatin organization GO:0070828 25 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
positive regulation of biosynthetic process GO:0009891 316 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.018
cellular response to dna damage stimulus GO:0006974 223 0.018
vesicle mediated transport GO:0016192 381 0.017
gene silencing by rna GO:0031047 57 0.017
defense response GO:0006952 300 0.017
ras protein signal transduction GO:0007265 88 0.017
single organism behavior GO:0044708 391 0.017
regulation of cell cycle GO:0051726 291 0.017
mitotic dna integrity checkpoint GO:0044774 75 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.017
single organism catabolic process GO:0044712 228 0.016
negative regulation of cell cycle GO:0045786 116 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
positive regulation of response to stimulus GO:0048584 323 0.016
organic acid metabolic process GO:0006082 103 0.016
regulation of mitotic cell cycle phase transition GO:1901990 130 0.016
regulation of rac gtpase activity GO:0032314 1 0.015
endocytosis GO:0006897 310 0.015
macromolecule catabolic process GO:0009057 161 0.015
larval development GO:0002164 104 0.015
negative regulation of signal transduction GO:0009968 206 0.015
catabolic process GO:0009056 409 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
g2 dna damage checkpoint GO:0031572 69 0.014
organelle fission GO:0048285 340 0.014
aromatic compound catabolic process GO:0019439 166 0.014
ribonucleoprotein complex subunit organization GO:0071826 28 0.014
heterocycle catabolic process GO:0046700 166 0.014
anterior posterior pattern specification GO:0009952 136 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
single organism membrane organization GO:0044802 93 0.014
regulation of protein modification process GO:0031399 112 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
protein modification process GO:0036211 438 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
negative regulation of mitotic cell cycle GO:0045930 109 0.013
phosphorylation GO:0016310 294 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
positive regulation of organelle organization GO:0010638 65 0.013
mitotic cell cycle phase transition GO:0044772 138 0.012
spliceosomal snrnp assembly GO:0000387 2 0.012
secretion GO:0046903 109 0.012
cellular protein localization GO:0034613 160 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
purine containing compound metabolic process GO:0072521 155 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
sister chromatid segregation GO:0000819 92 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
organic substance transport GO:0071702 257 0.012
protein methylation GO:0006479 43 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
chromatin remodeling GO:0006338 72 0.011
phagocytosis GO:0006909 215 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
dna damage checkpoint GO:0000077 78 0.011
chromosome segregation GO:0007059 157 0.011
regulation of cell cycle phase transition GO:1901987 130 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
cellular ketone metabolic process GO:0042180 24 0.010
regulation of transcription by chromatin organization GO:0034401 3 0.010
nucleoside metabolic process GO:0009116 127 0.010
positive regulation of cellular biosynthetic process GO:0031328 316 0.010
regulation of cellular protein metabolic process GO:0032268 243 0.010
negative regulation of signaling GO:0023057 219 0.010

MED28 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013