Drosophila melanogaster

0 known processes

wfs1 (Dmel_CG4917)

wolfram syndrome 1

(Aliases: CG4917,Dmel\CG4917)

wfs1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organonitrogen compound metabolic process GO:1901564 318 0.056
response to abiotic stimulus GO:0009628 341 0.052
establishment of localization in cell GO:0051649 402 0.050
positive regulation of macromolecule metabolic process GO:0010604 405 0.048
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.044
homeostatic process GO:0042592 199 0.043
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.041
response to radiation GO:0009314 155 0.040
positive regulation of response to stimulus GO:0048584 323 0.040
dna metabolic process GO:0006259 227 0.038
protein localization GO:0008104 284 0.037
positive regulation of biosynthetic process GO:0009891 316 0.034
regionalization GO:0003002 416 0.033
positive regulation of cellular biosynthetic process GO:0031328 316 0.031
positive regulation of signaling GO:0023056 243 0.031
positive regulation of rna metabolic process GO:0051254 271 0.030
protein modification process GO:0036211 438 0.030
chromosome organization GO:0051276 360 0.028
intracellular transport GO:0046907 228 0.028
positive regulation of cell communication GO:0010647 250 0.028
small molecule metabolic process GO:0044281 305 0.028
cellular catabolic process GO:0044248 372 0.027
imaginal disc derived appendage development GO:0048737 399 0.026
body morphogenesis GO:0010171 2 0.026
epithelial cell development GO:0002064 274 0.025
response to biotic stimulus GO:0009607 294 0.025
positive regulation of gene expression GO:0010628 290 0.025
cellular macromolecule localization GO:0070727 220 0.025
cellular amino acid metabolic process GO:0006520 61 0.024
appendage development GO:0048736 401 0.024
nucleobase containing small molecule metabolic process GO:0055086 174 0.024
transcription from rna polymerase ii promoter GO:0006366 368 0.024
intracellular signal transduction GO:0035556 300 0.024
phosphorylation GO:0016310 294 0.024
positive regulation of rna biosynthetic process GO:1902680 266 0.024
cellular response to dna damage stimulus GO:0006974 223 0.024
catabolic process GO:0009056 409 0.023
negative regulation of cellular metabolic process GO:0031324 382 0.023
telomere organization GO:0032200 21 0.023
nuclear division GO:0000280 332 0.023
regulation of phosphorus metabolic process GO:0051174 210 0.023
neurological system process GO:0050877 358 0.023
immune system process GO:0002376 347 0.023
regulation of immune system process GO:0002682 176 0.023
regulation of multicellular organismal development GO:2000026 414 0.022
regulation of response to stress GO:0080134 200 0.022
regulation of localization GO:0032879 275 0.021
carboxylic acid metabolic process GO:0019752 92 0.021
positive regulation of nucleic acid templated transcription GO:1903508 266 0.021
response to external biotic stimulus GO:0043207 293 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
ovarian follicle cell development GO:0030707 248 0.021
actin filament based process GO:0030029 220 0.021
regulation of protein metabolic process GO:0051246 256 0.021
oxoacid metabolic process GO:0043436 103 0.021
single organism intracellular transport GO:1902582 207 0.021
single organism catabolic process GO:0044712 228 0.021
regulation of molecular function GO:0065009 217 0.021
axon development GO:0061564 297 0.021
post embryonic appendage morphogenesis GO:0035120 385 0.021
ion transport GO:0006811 145 0.020
wing disc morphogenesis GO:0007472 344 0.020
brain development GO:0007420 120 0.020
organic acid metabolic process GO:0006082 103 0.020
positive regulation of signal transduction GO:0009967 223 0.020
anterior posterior pattern specification GO:0009952 136 0.020
programmed cell death GO:0012501 257 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
imaginal disc derived wing morphogenesis GO:0007476 337 0.020
negative regulation of response to stimulus GO:0048585 258 0.020
central nervous system development GO:0007417 201 0.020
cellular homeostasis GO:0019725 80 0.020
anatomical structure homeostasis GO:0060249 97 0.020
phagocytosis GO:0006909 215 0.020
appendage morphogenesis GO:0035107 397 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.019
organophosphate metabolic process GO:0019637 195 0.019
vesicle mediated transport GO:0016192 381 0.019
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.019
defense response GO:0006952 300 0.019
organelle fission GO:0048285 340 0.019
nucleoside phosphate metabolic process GO:0006753 162 0.019
transmembrane transport GO:0055085 139 0.019
nucleotide metabolic process GO:0009117 161 0.019
response to other organism GO:0051707 293 0.019
purine ribonucleotide metabolic process GO:0009150 145 0.019
cellular protein localization GO:0034613 160 0.019
regulation of transport GO:0051049 181 0.018
regulation of cell cycle GO:0051726 291 0.018
forebrain development GO:0030900 2 0.018
cell motility GO:0048870 251 0.018
immune response GO:0006955 246 0.018
endocytosis GO:0006897 310 0.018
cellular protein modification process GO:0006464 438 0.018
actin filament organization GO:0007015 126 0.018
regulation of anatomical structure size GO:0090066 163 0.018
cation transport GO:0006812 110 0.018
regulation of intracellular signal transduction GO:1902531 236 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.018
epithelial cell differentiation GO:0030855 322 0.018
macromolecular complex assembly GO:0065003 256 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
organic substance transport GO:0071702 257 0.018
heterocycle catabolic process GO:0046700 166 0.018
regulation of programmed cell death GO:0043067 152 0.018
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
compound eye development GO:0048749 307 0.017
cellular ketone metabolic process GO:0042180 24 0.017
imaginal disc derived appendage morphogenesis GO:0035114 395 0.017
positive regulation of transcription dna templated GO:0045893 266 0.017
proteolysis GO:0006508 192 0.017
response to oxygen containing compound GO:1901700 200 0.017
wnt signaling pathway GO:0016055 98 0.017
protein complex biogenesis GO:0070271 201 0.017
single organism behavior GO:0044708 391 0.017
regulation of catalytic activity GO:0050790 185 0.017
camera type eye development GO:0043010 4 0.017
death GO:0016265 284 0.017
localization of cell GO:0051674 257 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.017
columnar cuboidal epithelial cell development GO:0002066 249 0.017
response to ionizing radiation GO:0010212 32 0.017
ribonucleotide metabolic process GO:0009259 145 0.016
purine nucleoside triphosphate metabolic process GO:0009144 119 0.016
male gamete generation GO:0048232 201 0.016
regulation of organelle organization GO:0033043 196 0.016
cell death GO:0008219 279 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
photoreceptor cell differentiation GO:0046530 170 0.016
eye development GO:0001654 323 0.016
eye morphogenesis GO:0048592 260 0.016
actin cytoskeleton organization GO:0030036 206 0.016
purine containing compound metabolic process GO:0072521 155 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
regulation of apoptotic process GO:0042981 130 0.016
organic substance catabolic process GO:1901575 308 0.016
purine containing compound catabolic process GO:0072523 112 0.016
cellular amine metabolic process GO:0044106 12 0.016
negative regulation of signaling GO:0023057 219 0.016
regulation of immune response GO:0050776 118 0.015
regulation of cell death GO:0010941 173 0.015
ameboidal type cell migration GO:0001667 151 0.015
spermatogenesis GO:0007283 200 0.015
telencephalon development GO:0021537 2 0.015
compound eye morphogenesis GO:0001745 249 0.015
segmentation GO:0035282 207 0.015
ribonucleoside metabolic process GO:0009119 127 0.015
cell aging GO:0007569 2 0.015
axis specification GO:0009798 167 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
tissue morphogenesis GO:0048729 297 0.015
developmental maturation GO:0021700 172 0.015
growth GO:0040007 359 0.015
regulation of cell differentiation GO:0045595 302 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
protein phosphorylation GO:0006468 169 0.014
nitrogen compound transport GO:0071705 85 0.014
cell division GO:0051301 248 0.014
response to organic substance GO:0010033 284 0.014
single organism cellular localization GO:1902580 180 0.014
cell migration GO:0016477 238 0.014
axon guidance GO:0007411 233 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
regulation of cellular localization GO:0060341 136 0.014
axonogenesis GO:0007409 290 0.014
regulation of catabolic process GO:0009894 170 0.014
regulation of phosphate metabolic process GO:0019220 210 0.014
morphogenesis of an epithelium GO:0002009 276 0.014
protein complex assembly GO:0006461 200 0.014
purine ribonucleoside metabolic process GO:0046128 127 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.014
organonitrogen compound biosynthetic process GO:1901566 117 0.014
ribose phosphate metabolic process GO:0019693 145 0.014
negative regulation of signal transduction GO:0009968 206 0.014
meiotic nuclear division GO:0007126 151 0.014
ribonucleoside catabolic process GO:0042454 112 0.013
amine metabolic process GO:0009308 12 0.013
chemotaxis GO:0006935 249 0.013
chromatin remodeling GO:0006338 72 0.013
tripartite regional subdivision GO:0007351 103 0.013
aromatic compound catabolic process GO:0019439 166 0.013
cell maturation GO:0048469 144 0.013
eye photoreceptor cell differentiation GO:0001754 145 0.013
chromatin organization GO:0006325 207 0.013
immune response regulating signaling pathway GO:0002764 2 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
defense response to gram negative bacterium GO:0050829 94 0.013
chromosome segregation GO:0007059 157 0.013
embryonic pattern specification GO:0009880 174 0.013
defense response to bacterium GO:0042742 178 0.013
protein modification by small protein conjugation or removal GO:0070647 106 0.013
nucleoside metabolic process GO:0009116 127 0.013
regulation of protein modification process GO:0031399 112 0.013
response to bacterium GO:0009617 198 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.013
developmental programmed cell death GO:0010623 138 0.013
lipid metabolic process GO:0006629 121 0.013
centrosome duplication GO:0051298 121 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
protein transport GO:0015031 155 0.013
open tracheal system development GO:0007424 204 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
negative regulation of rna biosynthetic process GO:1902679 240 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
tube development GO:0035295 244 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
developmental growth GO:0048589 280 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
blastoderm segmentation GO:0007350 159 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
chromatin modification GO:0016568 147 0.012
sensory organ morphogenesis GO:0090596 260 0.012
lateral inhibition GO:0046331 206 0.012
jak stat cascade GO:0007259 49 0.012
regulation of cell development GO:0060284 215 0.012
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
peptide metabolic process GO:0006518 80 0.012
membrane organization GO:0061024 112 0.012
monocarboxylic acid transport GO:0015718 3 0.012
centrosome organization GO:0051297 163 0.012
head development GO:0060322 135 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
inorganic ion transmembrane transport GO:0098660 73 0.012
ion transmembrane transport GO:0034220 122 0.012
immune response activating signal transduction GO:0002757 2 0.012
telomere maintenance GO:0000723 21 0.012
connective tissue development GO:0061448 3 0.012
cation transmembrane transport GO:0098655 88 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
taxis GO:0042330 304 0.012
chemical homeostasis GO:0048878 92 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
positive regulation of cell motility GO:2000147 3 0.011
embryonic morphogenesis GO:0048598 206 0.011
negative regulation of gene expression GO:0010629 387 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
single organism membrane organization GO:0044802 93 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
anterior posterior axis specification GO:0009948 109 0.011
respiratory system development GO:0060541 213 0.011
endomembrane system organization GO:0010256 119 0.011
positive regulation of immune system process GO:0002684 68 0.011
regulation of defense response GO:0031347 102 0.011
macromolecule catabolic process GO:0009057 161 0.011
response to temperature stimulus GO:0009266 106 0.011
aging GO:0007568 143 0.011
microtubule organizing center organization GO:0031023 168 0.011
cellular amide metabolic process GO:0043603 80 0.011
wound healing GO:0042060 75 0.011
protein processing GO:0016485 68 0.011
atp metabolic process GO:0046034 49 0.011
response to lipopolysaccharide GO:0032496 4 0.011
defense response to other organism GO:0098542 225 0.011
locomotory behavior GO:0007626 176 0.011
positive regulation of lipid metabolic process GO:0045834 4 0.011
positive regulation of apoptotic signaling pathway GO:2001235 4 0.011
adult behavior GO:0030534 137 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
cellularization GO:0007349 90 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
response to wounding GO:0009611 94 0.011
cytoplasmic transport GO:0016482 130 0.011
establishment of protein localization GO:0045184 163 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.010
protein modification by small protein conjugation GO:0032446 79 0.010
cell proliferation GO:0008283 299 0.010
positive regulation of transport GO:0051050 92 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
regulation of cellular component size GO:0032535 98 0.010
positive regulation of cell migration GO:0030335 2 0.010
maintenance of location GO:0051235 73 0.010
nucleoside catabolic process GO:0009164 112 0.010
negative regulation of cell communication GO:0010648 223 0.010
embryonic axis specification GO:0000578 107 0.010
single organism biosynthetic process GO:0044711 206 0.010
regulation of protein localization GO:0032880 76 0.010
erbb signaling pathway GO:0038127 58 0.010
innate immune response GO:0045087 144 0.010
regulation of cell cycle process GO:0010564 181 0.010
embryonic development via the syncytial blastoderm GO:0001700 148 0.010
cellular component assembly involved in morphogenesis GO:0010927 151 0.010
rna localization GO:0006403 115 0.010
tube morphogenesis GO:0035239 191 0.010
anterior posterior axis specification embryo GO:0008595 103 0.010
positive regulation of catabolic process GO:0009896 105 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.010

wfs1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.053
nervous system disease DOID:863 0 0.021
cardiovascular system disease DOID:1287 0 0.012
disease of metabolism DOID:0014667 0 0.012
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010
central nervous system disease DOID:331 0 0.010