Drosophila melanogaster

22 known processes

alpha-Est7 (Dmel_CG1112)

alpha-Esterase-7

(Aliases: Dmel\CG1112,EST23,alphaE7,aE7,CG1112,H,Est-23,Ali,DmalphaE7,Est23,alphaest-7,ali,Mce)

alpha-Est7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to mercury ion GO:0046689 3 0.869
insecticide metabolic process GO:0017143 2 0.828
organic hydroxy compound metabolic process GO:1901615 83 0.611
Fly
medium chain fatty acid metabolic process GO:0051791 1 0.548
small molecule metabolic process GO:0044281 305 0.505
Fly
secondary metabolite catabolic process GO:0090487 1 0.453
fat soluble vitamin metabolic process GO:0006775 1 0.370
single organism behavior GO:0044708 391 0.368
organonitrogen compound metabolic process GO:1901564 318 0.346
Fly
regulation of tube size GO:0035150 46 0.334
Fly
lauric acid metabolic process GO:0048252 1 0.327
vitamin metabolic process GO:0006766 2 0.315
single organism biosynthetic process GO:0044711 206 0.309
epithelial cell development GO:0002064 274 0.303
Fly
regulation of anatomical structure size GO:0090066 163 0.303
Fly
polyol biosynthetic process GO:0046173 3 0.292
border follicle cell migration GO:0007298 113 0.283
Fly
response to external biotic stimulus GO:0043207 293 0.258
Fly
vitamin biosynthetic process GO:0009110 1 0.245
cellular ketone metabolic process GO:0042180 24 0.235
chemical homeostasis GO:0048878 92 0.230
sterol metabolic process GO:0016125 12 0.218
homeostatic process GO:0042592 199 0.207
columnar cuboidal epithelial cell development GO:0002066 249 0.204
Fly
response to biotic stimulus GO:0009607 294 0.190
Fly
alcohol metabolic process GO:0006066 25 0.187
Fly
alcohol biosynthetic process GO:0046165 14 0.184
growth GO:0040007 359 0.179
organic acid metabolic process GO:0006082 103 0.174
response to organophosphorus GO:0046683 2 0.174
response to organic substance GO:0010033 284 0.172
fat soluble vitamin biosynthetic process GO:0042362 1 0.170
ovarian follicle cell migration GO:0007297 121 0.169
Fly
epithelium migration GO:0090132 148 0.169
Fly
response to toxic substance GO:0009636 22 0.168
organic hydroxy compound biosynthetic process GO:1901617 21 0.160
steroid catabolic process GO:0006706 1 0.160
response to glucose GO:0009749 2 0.159
hormone metabolic process GO:0042445 33 0.152
acetylcholine metabolic process GO:0008291 2 0.152
Fly
response to other organism GO:0051707 293 0.151
Fly
ovarian follicle cell development GO:0030707 248 0.151
Fly
oxidation reduction process GO:0055114 123 0.149
cellular catabolic process GO:0044248 372 0.149
Fly
synaptic transmission GO:0007268 288 0.144
Fly
oxoacid metabolic process GO:0043436 103 0.141
axon guidance GO:0007411 233 0.138
Fly
carboxylic acid metabolic process GO:0019752 92 0.137
regulation of growth GO:0040008 233 0.135
aging GO:0007568 143 0.132
secondary metabolic process GO:0019748 75 0.132
fatty acid metabolic process GO:0006631 20 0.127
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.127
Fly
cellular ion homeostasis GO:0006873 39 0.126
regionalization GO:0003002 416 0.126
Fly
epithelial cell migration GO:0010631 148 0.122
Fly
tissue migration GO:0090130 155 0.119
Fly
epithelial cell differentiation GO:0030855 322 0.117
Fly
regulation of developmental growth GO:0048638 174 0.116
cellular hormone metabolic process GO:0034754 23 0.112
response to insecticide GO:0017085 14 0.112
hormone biosynthetic process GO:0042446 20 0.112
ameboidal type cell migration GO:0001667 151 0.111
Fly
organic substance catabolic process GO:1901575 308 0.106
Fly
organonitrogen compound catabolic process GO:1901565 128 0.106
Fly
motor neuron axon guidance GO:0008045 58 0.106
Fly
response to ddt GO:0046680 5 0.105
xenobiotic catabolic process GO:0042178 1 0.104
toxin catabolic process GO:0009407 1 0.103
insecticide catabolic process GO:0046701 1 0.100
choline catabolic process GO:0042426 1 0.100
Fly
defense response to other organism GO:0098542 225 0.098
Fly
developmental growth GO:0048589 280 0.098
defense response to gram negative bacterium GO:0050829 94 0.096
ecdysteroid biosynthetic process GO:0045456 15 0.089
steroid metabolic process GO:0008202 20 0.089
response to extracellular stimulus GO:0009991 116 0.088
single organism catabolic process GO:0044712 228 0.086
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.085
ethanolamine containing compound metabolic process GO:0042439 4 0.082
Fly
lipid metabolic process GO:0006629 121 0.082
sterol biosynthetic process GO:0016126 9 0.081
monocarboxylic acid metabolic process GO:0032787 29 0.080
regulation of cellular ketone metabolic process GO:0010565 3 0.079
response to oxygen containing compound GO:1901700 200 0.078
sensory perception GO:0007600 196 0.078
aggressive behavior GO:0002118 63 0.078
lipid biosynthetic process GO:0008610 46 0.077
cellular response to chemical stimulus GO:0070887 199 0.076
choline metabolic process GO:0019695 1 0.075
Fly
response to light stimulus GO:0009416 124 0.072
Fly
amine catabolic process GO:0009310 1 0.072
Fly
ketone biosynthetic process GO:0042181 16 0.070
ecdysteroid metabolic process GO:0045455 19 0.068
catabolic process GO:0009056 409 0.067
Fly
localization of cell GO:0051674 257 0.066
Fly
response to nutrient levels GO:0031667 114 0.065
cellular amine metabolic process GO:0044106 12 0.065
Fly
nucleobase containing small molecule metabolic process GO:0055086 174 0.065
epidermal cell differentiation GO:0009913 51 0.063
Fly
cellular homeostasis GO:0019725 80 0.063
response to oxidative stress GO:0006979 86 0.062
organelle fission GO:0048285 340 0.062
Fly
toxin metabolic process GO:0009404 2 0.061
tube development GO:0035295 244 0.061
tergite morphogenesis GO:0007490 1 0.061
chromosome segregation GO:0007059 157 0.059
Fly
regulation of hormone levels GO:0010817 40 0.059
response to bacterium GO:0009617 198 0.059
neurotransmitter catabolic process GO:0042135 1 0.056
Fly
multi organism behavior GO:0051705 175 0.056
Fly
response to abiotic stimulus GO:0009628 341 0.056
Fly
cellular amino acid metabolic process GO:0006520 61 0.056
ecdysone metabolic process GO:0008205 11 0.055
small molecule biosynthetic process GO:0044283 37 0.055
regulation of cellular localization GO:0060341 136 0.054
organophosphate metabolic process GO:0019637 195 0.054
neuron projection guidance GO:0097485 241 0.054
Fly
positive regulation of gene expression GO:0010628 290 0.054
peptide metabolic process GO:0006518 80 0.052
anion homeostasis GO:0055081 3 0.052
positive regulation of multicellular organismal process GO:0051240 143 0.051
response to nitrogen compound GO:1901698 90 0.048
amine metabolic process GO:0009308 12 0.048
Fly
detection of stimulus GO:0051606 156 0.048
terpenoid metabolic process GO:0006721 7 0.047
neurological system process GO:0050877 358 0.047
cellular response to extracellular stimulus GO:0031668 64 0.047
cellular lipid metabolic process GO:0044255 83 0.047
neurotransmitter metabolic process GO:0042133 2 0.047
Fly
cellular nitrogen compound catabolic process GO:0044270 165 0.047
defense response to bacterium GO:0042742 178 0.047
cell migration GO:0016477 238 0.047
Fly
defense response GO:0006952 300 0.046
Fly
cell death GO:0008219 279 0.045
nuclear division GO:0000280 332 0.044
Fly
axonogenesis GO:0007409 290 0.043
Fly
chemotaxis GO:0006935 249 0.041
Fly
lipid catabolic process GO:0016042 21 0.041
female meiosis chromosome segregation GO:0016321 33 0.041
Fly
meiotic cell cycle GO:0051321 171 0.040
Fly
response to metal ion GO:0010038 23 0.040
dorsal closure GO:0007391 79 0.040
sensory perception of smell GO:0007608 80 0.039
programmed cell death GO:0012501 257 0.039
actin cytoskeleton organization GO:0030036 206 0.039
enzyme linked receptor protein signaling pathway GO:0007167 179 0.039
response to ethanol GO:0045471 59 0.039
positive regulation of signaling GO:0023056 243 0.038
response to monosaccharide GO:0034284 4 0.038
cellular response to external stimulus GO:0071496 66 0.038
steroid biosynthetic process GO:0006694 16 0.037
skin development GO:0043588 65 0.037
Fly
signal release GO:0023061 49 0.037
response to fungus GO:0009620 50 0.036
positive regulation of biosynthetic process GO:0009891 316 0.036
organic substance transport GO:0071702 257 0.036
cell cell signaling involved in cell fate commitment GO:0045168 210 0.036
behavioral response to ethanol GO:0048149 49 0.036
ion homeostasis GO:0050801 55 0.036
positive regulation of cell communication GO:0010647 250 0.035
cellular response to oxidative stress GO:0034599 28 0.035
acetate ester metabolic process GO:1900619 2 0.035
Fly
response to temperature stimulus GO:0009266 106 0.034
negative regulation of cellular metabolic process GO:0031324 382 0.034
respiratory system development GO:0060541 213 0.034
Fly
negative regulation of biosynthetic process GO:0009890 277 0.034
multicellular organismal aging GO:0010259 140 0.034
epidermis development GO:0008544 65 0.033
Fly
secretion GO:0046903 109 0.033
lateral inhibition GO:0046331 206 0.033
response to endogenous stimulus GO:0009719 119 0.032
cell motility GO:0048870 251 0.032
Fly
organic cyclic compound catabolic process GO:1901361 168 0.032
melanin metabolic process GO:0006582 47 0.032
pigment metabolic process GO:0042440 84 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.031
cellular response to uv GO:0034644 12 0.031
cell cell junction organization GO:0045216 55 0.031
Fly
regulation of blood circulation GO:1903522 21 0.031
cellular amide metabolic process GO:0043603 80 0.031
post embryonic appendage morphogenesis GO:0035120 385 0.031
Fly
embryonic development via the syncytial blastoderm GO:0001700 148 0.031
response to organonitrogen compound GO:0010243 75 0.030
female meiotic division GO:0007143 70 0.030
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.030
death GO:0016265 284 0.030
immune system process GO:0002376 347 0.029
imaginal disc derived appendage development GO:0048737 399 0.029
Fly
immune effector process GO:0002252 98 0.029
purine containing compound metabolic process GO:0072521 155 0.029
apical junction assembly GO:0043297 32 0.029
Fly
organonitrogen compound biosynthetic process GO:1901566 117 0.029
apoptotic process GO:0006915 159 0.029
immune response GO:0006955 246 0.028
ecdysone biosynthetic process GO:0006697 9 0.028
axon development GO:0061564 297 0.028
Fly
protein complex assembly GO:0006461 200 0.028
acetylcholine catabolic process GO:0006581 1 0.028
Fly
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.027
detection of chemical stimulus GO:0009593 93 0.027
camera type eye development GO:0043010 4 0.027
imaginal disc derived wing morphogenesis GO:0007476 337 0.027
Fly
regulation of tube architecture open tracheal system GO:0035152 68 0.027
Fly
cellular response to starvation GO:0009267 61 0.027
cellular response to heat GO:0034605 24 0.027
adult behavior GO:0030534 137 0.026
cuticle development GO:0042335 86 0.026
cellular chemical homeostasis GO:0055082 40 0.026
nucleoside phosphate metabolic process GO:0006753 162 0.026
cell cell junction assembly GO:0007043 38 0.025
Fly
ras protein signal transduction GO:0007265 88 0.025
establishment of localization in cell GO:0051649 402 0.025
spermatogenesis GO:0007283 200 0.025
Fly
morphogenesis of embryonic epithelium GO:0016331 94 0.025
morphogenesis of an epithelium GO:0002009 276 0.025
connective tissue development GO:0061448 3 0.024
response to alkaloid GO:0043279 26 0.023
response to hexose GO:0009746 3 0.023
melanotic encapsulation of foreign target GO:0035011 30 0.023
wing disc morphogenesis GO:0007472 344 0.023
Fly
cell junction organization GO:0034330 57 0.023
Fly
oxidoreduction coenzyme metabolic process GO:0006733 2 0.023
chaeta development GO:0022416 97 0.023
central nervous system development GO:0007417 201 0.022
innate immune response GO:0045087 144 0.022
digestive system development GO:0055123 149 0.022
negative regulation of cellular component organization GO:0051129 108 0.022
negative regulation of cellular biosynthetic process GO:0031327 277 0.022
cellular biogenic amine catabolic process GO:0042402 1 0.022
Fly
regulation of transport GO:0051049 181 0.021
energy derivation by oxidation of organic compounds GO:0015980 32 0.021
regulation of system process GO:0044057 36 0.021
cellular protein modification process GO:0006464 438 0.021
melanization defense response GO:0035006 45 0.021
circulatory system process GO:0003013 37 0.021
meiotic cell cycle process GO:1903046 132 0.021
Fly
open tracheal system development GO:0007424 204 0.021
Fly
response to caffeine GO:0031000 12 0.020
wound healing GO:0042060 75 0.020
energy taxis GO:0009453 21 0.020
Fly
tissue morphogenesis GO:0048729 297 0.020
protein modification process GO:0036211 438 0.020
actin filament based process GO:0030029 220 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.019
hair cell differentiation GO:0035315 47 0.019
Fly
positive regulation of cell migration GO:0030335 2 0.019
regulation of immune system process GO:0002682 176 0.019
male gamete generation GO:0048232 201 0.018
Fly
intracellular signal transduction GO:0035556 300 0.018
secretion by cell GO:0032940 101 0.018
appendage morphogenesis GO:0035107 397 0.018
Fly
carbohydrate derivative metabolic process GO:1901135 217 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.018
appendage development GO:0048736 401 0.018
Fly
mating behavior GO:0007617 106 0.018
Fly
thermosensory behavior GO:0040040 19 0.018
organic hydroxy compound catabolic process GO:1901616 4 0.018
Fly
regulation of neurotransmitter levels GO:0001505 38 0.017
Fly
regulation of organelle organization GO:0033043 196 0.017
macromolecular complex assembly GO:0065003 256 0.017
regulation of secretion by cell GO:1903530 39 0.017
isoprenoid metabolic process GO:0006720 8 0.017
blood circulation GO:0008015 26 0.016
pyridine containing compound metabolic process GO:0072524 3 0.016
hormone catabolic process GO:0042447 3 0.016
regulation of apoptotic process GO:0042981 130 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.016
response to purine containing compound GO:0014074 12 0.016
regulation of localization GO:0032879 275 0.016
proteolysis GO:0006508 192 0.016
response to alcohol GO:0097305 95 0.016
regulation of secretion GO:0051046 44 0.016
monocarboxylic acid transport GO:0015718 3 0.015
pyridine nucleotide metabolic process GO:0019362 2 0.015
response to cadmium ion GO:0046686 9 0.015
positive regulation of secretion GO:0051047 22 0.015
salivary gland morphogenesis GO:0007435 145 0.015
response to radiation GO:0009314 155 0.015
Fly
digestive tract development GO:0048565 149 0.015
biological adhesion GO:0022610 138 0.015
Fly
response to inorganic substance GO:0010035 44 0.015
circadian behavior GO:0048512 76 0.015
positive regulation of cellular catabolic process GO:0031331 95 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
imaginal disc derived appendage morphogenesis GO:0035114 395 0.015
Fly
chitin based cuticle development GO:0040003 49 0.015
regulation of cell morphogenesis GO:0022604 163 0.015
embryonic morphogenesis GO:0048598 206 0.015
g protein coupled receptor signaling pathway GO:0007186 136 0.015
positive regulation of cell motility GO:2000147 3 0.014
dna metabolic process GO:0006259 227 0.014
multicellular organismal reproductive behavior GO:0033057 110 0.014
Fly
reproductive behavior GO:0019098 122 0.014
Fly
nucleobase containing compound catabolic process GO:0034655 165 0.014
regulation of innate immune response GO:0045088 71 0.014
positive regulation of response to stimulus GO:0048584 323 0.014
response to hormone GO:0009725 45 0.014
phosphorylation GO:0016310 294 0.014
regulation of cell death GO:0010941 173 0.014
positive regulation of cell differentiation GO:0045597 64 0.014
positive regulation of cell death GO:0010942 69 0.014
phosphatidylinositol mediated signaling GO:0048015 4 0.013
heterocycle catabolic process GO:0046700 166 0.013
purine nucleoside metabolic process GO:0042278 127 0.013
multi multicellular organism process GO:0044706 123 0.013
Fly
carbohydrate homeostasis GO:0033500 12 0.013
cellular response to nutrient levels GO:0031669 62 0.013
cell junction assembly GO:0034329 42 0.013
Fly
aromatic compound catabolic process GO:0019439 166 0.013
compound eye morphogenesis GO:0001745 249 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
positive regulation of catabolic process GO:0009896 105 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.013
nicotinamide nucleotide metabolic process GO:0046496 2 0.013
carbohydrate biosynthetic process GO:0016051 17 0.013
carbohydrate metabolic process GO:0005975 82 0.012
phototransduction GO:0007602 52 0.012
response to transition metal nanoparticle GO:1990267 9 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
regulation of cell differentiation GO:0045595 302 0.012
response to organic cyclic compound GO:0014070 89 0.012
non sensory hair organization GO:0035316 47 0.012
Fly
regulation of catalytic activity GO:0050790 185 0.012
heart morphogenesis GO:0003007 32 0.012
Fly
transmembrane transport GO:0055085 139 0.012
macromolecule catabolic process GO:0009057 161 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
actin filament organization GO:0007015 126 0.011
cellular response to endogenous stimulus GO:0071495 80 0.011
neuropeptide signaling pathway GO:0007218 45 0.011
cellular polysaccharide biosynthetic process GO:0033692 7 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
positive regulation of transport GO:0051050 92 0.011
defense response to fungus GO:0050832 48 0.011
nucleotide metabolic process GO:0009117 161 0.011
cardiovascular system development GO:0072358 82 0.011
Fly
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
retina development in camera type eye GO:0060041 4 0.011
positive regulation of signal transduction GO:0009967 223 0.011
cellular modified amino acid metabolic process GO:0006575 45 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
cation homeostasis GO:0055080 51 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
cellular component disassembly GO:0022411 46 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
regulation of cellular component size GO:0032535 98 0.010
regulation of cellular amine metabolic process GO:0033238 3 0.010
pigment metabolic process involved in pigmentation GO:0043474 33 0.010
nitrogen compound transport GO:0071705 85 0.010
peripheral nervous system development GO:0007422 52 0.010
Fly
multi organism reproductive behavior GO:0044705 121 0.010
Fly
nucleoside metabolic process GO:0009116 127 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
cellular biogenic amine metabolic process GO:0006576 9 0.010
Fly

alpha-Est7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
hypertension DOID:10763 0 0.408
artery disease DOID:0050828 0 0.408
disease of anatomical entity DOID:7 0 0.408
vascular disease DOID:178 0 0.408
essential hypertension DOID:10825 0 0.408
cardiovascular system disease DOID:1287 0 0.408
disease of metabolism DOID:0014667 0 0.036
acquired metabolic disease DOID:0060158 0 0.018
nervous system disease DOID:863 0 0.016
central nervous system disease DOID:331 0 0.013
neurodegenerative disease DOID:1289 0 0.012
carbohydrate metabolism disease DOID:0050013 0 0.011
inherited metabolic disorder DOID:655 0 0.011