Drosophila melanogaster

84 known processes

dnt (Dmel_CG17559)

doughnut on 2

(Aliases: Dmel\CG17559,CG17559)

dnt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived appendage development GO:0048737 399 0.323
Fly
salivary gland morphogenesis GO:0007435 145 0.246
tube morphogenesis GO:0035239 191 0.238
Zebrafish
salivary gland development GO:0007431 162 0.230
gland morphogenesis GO:0022612 145 0.218
dna endoreduplication GO:0042023 22 0.212
ribonucleoside metabolic process GO:0009119 127 0.211
tube development GO:0035295 244 0.176
Zebrafish
exocrine system development GO:0035272 162 0.155
positive regulation of macromolecule metabolic process GO:0010604 405 0.148
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.144
dna metabolic process GO:0006259 227 0.136
response to alcohol GO:0097305 95 0.130
single organism behavior GO:0044708 391 0.121
Fly
muscle structure development GO:0061061 224 0.109
imaginal disc derived appendage morphogenesis GO:0035114 395 0.103
appendage development GO:0048736 401 0.100
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.099
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.088
guanosine containing compound metabolic process GO:1901068 74 0.081
positive regulation of gene expression GO:0010628 290 0.078
catabolic process GO:0009056 409 0.072
post embryonic appendage morphogenesis GO:0035120 385 0.071
positive regulation of programmed cell death GO:0043068 62 0.069
positive regulation of rna metabolic process GO:0051254 271 0.068
respiratory system development GO:0060541 213 0.066
oxoacid metabolic process GO:0043436 103 0.064
response to biotic stimulus GO:0009607 294 0.063
establishment of localization in cell GO:0051649 402 0.062
Zebrafish
chromatin assembly or disassembly GO:0006333 52 0.061
syncytial blastoderm mitotic cell cycle GO:0035186 21 0.059
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.058
positive regulation of nucleic acid templated transcription GO:1903508 266 0.057
organonitrogen compound metabolic process GO:1901564 318 0.055
positive regulation of phosphorus metabolic process GO:0010562 139 0.055
Human
cell death GO:0008219 279 0.054
negative regulation of developmental growth GO:0048640 64 0.054
Mouse
nucleobase containing compound catabolic process GO:0034655 165 0.053
histone lysine demethylation GO:0070076 6 0.053
compound eye development GO:0048749 307 0.051
negative regulation of developmental process GO:0051093 201 0.051
Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.051
purine nucleoside metabolic process GO:0042278 127 0.050
developmental growth GO:0048589 280 0.050
Zebrafish Mouse
muscle attachment GO:0016203 36 0.048
positive regulation of signal transduction GO:0009967 223 0.047
Human
purine containing compound metabolic process GO:0072521 155 0.047
glycosyl compound metabolic process GO:1901657 127 0.047
regionalization GO:0003002 416 0.046
Worm
ribonucleoside triphosphate metabolic process GO:0009199 119 0.046
cellular nitrogen compound catabolic process GO:0044270 165 0.045
nucleobase containing small molecule metabolic process GO:0055086 174 0.044
ribonucleoside catabolic process GO:0042454 112 0.044
regulation of cell death GO:0010941 173 0.044
axon choice point recognition GO:0016198 26 0.043
Fly
taxis GO:0042330 304 0.043
digestive tract morphogenesis GO:0048546 127 0.043
Zebrafish
induction of programmed cell death by ecdysone GO:0035078 12 0.043
camera type eye morphogenesis GO:0048593 2 0.043
muscle organ development GO:0007517 127 0.042
intracellular signal transduction GO:0035556 300 0.042
Human
embryonic development via the syncytial blastoderm GO:0001700 148 0.042
positive regulation of cell communication GO:0010647 250 0.041
Human
histolysis GO:0007559 102 0.041
tissue death GO:0016271 102 0.041
regulation of cellular ketone metabolic process GO:0010565 3 0.040
macromolecular complex assembly GO:0065003 256 0.040
gland development GO:0048732 191 0.039
gliogenesis GO:0042063 80 0.039
ecdysone mediated induction of salivary gland cell autophagic cell death GO:0035072 12 0.038
positive regulation of cellular protein metabolic process GO:0032270 118 0.038
formation of organ boundary GO:0010160 30 0.037
ribonucleoside triphosphate catabolic process GO:0009203 108 0.037
cell cycle dna replication GO:0044786 23 0.037
nuclear division GO:0000280 332 0.037
carboxylic acid metabolic process GO:0019752 92 0.036
chemosensory behavior GO:0007635 106 0.036
Fly
programmed cell death GO:0012501 257 0.036
embryonic morphogenesis GO:0048598 206 0.035
Zebrafish
cell proliferation GO:0008283 299 0.035
developmental programmed cell death GO:0010623 138 0.035
response to oxygen containing compound GO:1901700 200 0.035
glial cell migration GO:0008347 31 0.035
induction of programmed cell death by hormones GO:0035081 12 0.035
retina morphogenesis in camera type eye GO:0060042 2 0.034
organophosphate metabolic process GO:0019637 195 0.034
negative regulation of cell differentiation GO:0045596 143 0.034
Mouse
dendrite morphogenesis GO:0048813 199 0.034
positive regulation of cellular biosynthetic process GO:0031328 316 0.033
regulation of immune response GO:0050776 118 0.032
defense response GO:0006952 300 0.032
organelle fission GO:0048285 340 0.032
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.032
purine containing compound catabolic process GO:0072523 112 0.032
organonitrogen compound catabolic process GO:1901565 128 0.032
response to ecdysone GO:0035075 34 0.032
cell junction organization GO:0034330 57 0.031
guanosine containing compound catabolic process GO:1901069 74 0.031
cellular amino acid metabolic process GO:0006520 61 0.031
spindle organization GO:0007051 253 0.031
extrinsic apoptotic signaling pathway GO:0097191 1 0.031
negative regulation of axon extension GO:0030517 3 0.030
Mouse
chromatin organization GO:0006325 207 0.030
regulation of cellular amino acid metabolic process GO:0006521 0 0.030
regulation of programmed cell death GO:0043067 152 0.030
phosphatidylinositol mediated signaling GO:0048015 4 0.030
dendrite development GO:0016358 204 0.030
death GO:0016265 284 0.029
nucleotide catabolic process GO:0009166 109 0.029
axonogenesis GO:0007409 290 0.029
regulation of organelle organization GO:0033043 196 0.029
olfactory behavior GO:0042048 97 0.029
Fly
ribose phosphate metabolic process GO:0019693 145 0.029
nucleoside metabolic process GO:0009116 127 0.028
carbohydrate derivative metabolic process GO:1901135 217 0.028
apoptotic signaling pathway GO:0097190 27 0.028
body morphogenesis GO:0010171 2 0.028
purine nucleotide metabolic process GO:0006163 146 0.028
open tracheal system development GO:0007424 204 0.027
regulation of dna metabolic process GO:0051052 34 0.027
purine ribonucleotide metabolic process GO:0009150 145 0.027
induction of programmed cell death GO:0012502 12 0.027
protein maturation GO:0051604 71 0.026
regulation of anatomical structure size GO:0090066 163 0.026
Mouse
dna replication GO:0006260 48 0.026
purine ribonucleoside metabolic process GO:0046128 127 0.026
regulation of cellular amine metabolic process GO:0033238 3 0.026
single organism biosynthetic process GO:0044711 206 0.026
response to ionizing radiation GO:0010212 32 0.026
positive regulation of transcription dna templated GO:0045893 266 0.026
regulation of cell substrate adhesion GO:0010810 2 0.026
glycosyl compound catabolic process GO:1901658 112 0.025
tissue morphogenesis GO:0048729 297 0.025
Zebrafish Worm
response to external biotic stimulus GO:0043207 293 0.025
heterocycle catabolic process GO:0046700 166 0.025
defense response to other organism GO:0098542 225 0.025
ras protein signal transduction GO:0007265 88 0.025
regulation of immune system process GO:0002682 176 0.025
appendage morphogenesis GO:0035107 397 0.025
positive regulation of phosphorylation GO:0042327 87 0.025
Human
salivary gland cell autophagic cell death GO:0035071 83 0.025
cell growth GO:0016049 108 0.024
Mouse
eye development GO:0001654 323 0.024
imaginal disc derived wing morphogenesis GO:0007476 337 0.024
salivary gland histolysis GO:0035070 88 0.024
organic acid metabolic process GO:0006082 103 0.024
photoreceptor cell development GO:0042461 96 0.024
growth GO:0040007 359 0.024
Zebrafish Mouse
cognition GO:0050890 141 0.024
Fly
protein dna complex assembly GO:0065004 63 0.024
embryo development ending in birth or egg hatching GO:0009792 152 0.024
purine ribonucleotide catabolic process GO:0009154 109 0.024
positive regulation of biosynthetic process GO:0009891 316 0.023
transcription from rna polymerase ii promoter GO:0006366 368 0.023
response to wounding GO:0009611 94 0.023
formation of anatomical boundary GO:0048859 37 0.023
ribonucleotide metabolic process GO:0009259 145 0.023
brain development GO:0007420 120 0.023
Mouse
eye morphogenesis GO:0048592 260 0.022
morphogenesis of an epithelium GO:0002009 276 0.022
Zebrafish Worm
branching morphogenesis of an epithelial tube GO:0048754 45 0.022
wing disc morphogenesis GO:0007472 344 0.022
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.022
purine nucleotide catabolic process GO:0006195 109 0.022
response to other organism GO:0051707 293 0.022
response to sterol GO:0036314 34 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.022
developmental cell growth GO:0048588 52 0.021
Mouse
positive regulation of intracellular signal transduction GO:1902533 116 0.021
Human
phagocytosis GO:0006909 215 0.021
retina development in camera type eye GO:0060041 4 0.021
cell cell junction organization GO:0045216 55 0.021
forebrain development GO:0030900 2 0.021
Mouse
positive regulation of response to stimulus GO:0048584 323 0.021
Human
single organism cell adhesion GO:0098602 47 0.021
regulation of cell differentiation GO:0045595 302 0.021
Mouse
aromatic compound catabolic process GO:0019439 166 0.021
nucleoside catabolic process GO:0009164 112 0.021
regulation of protein metabolic process GO:0051246 256 0.021
regulation of mapk cascade GO:0043408 92 0.020
Human
sensory perception GO:0007600 196 0.020
actin filament organization GO:0007015 126 0.020
positive regulation of molecular function GO:0044093 136 0.020
immune effector process GO:0002252 98 0.020
nephron development GO:0072006 3 0.020
positive regulation of dna endoreduplication GO:0032877 4 0.020
inositol lipid mediated signaling GO:0048017 4 0.020
chromatin modification GO:0016568 147 0.020
organic cyclic compound catabolic process GO:1901361 168 0.019
regulation of gene expression epigenetic GO:0040029 128 0.019
regulation of phosphate metabolic process GO:0019220 210 0.019
Human
nucleoside triphosphate catabolic process GO:0009143 108 0.019
morphogenesis of a branching epithelium GO:0061138 45 0.019
chromatin remodeling GO:0006338 72 0.019
protein dna complex subunit organization GO:0071824 86 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
Human
digestive tract development GO:0048565 149 0.019
Zebrafish
actin filament bundle organization GO:0061572 28 0.019
branching involved in open tracheal system development GO:0060446 45 0.019
cellular catabolic process GO:0044248 372 0.018
gtp metabolic process GO:0046039 72 0.018
karyosome formation GO:0030717 22 0.018
carbohydrate derivative catabolic process GO:1901136 118 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.018
dna packaging GO:0006323 91 0.018
negative regulation of nervous system development GO:0051961 92 0.018
Mouse
response to ketone GO:1901654 34 0.018
response to organic cyclic compound GO:0014070 89 0.018
positive regulation of nucleotide catabolic process GO:0030813 46 0.018
organic substance catabolic process GO:1901575 308 0.018
response to insulin GO:0032868 29 0.018
gtp catabolic process GO:0006184 72 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
cell motility GO:0048870 251 0.018
Zebrafish
spindle assembly GO:0051225 80 0.017
olfactory learning GO:0008355 56 0.017
Fly
positive regulation of cellular amine metabolic process GO:0033240 0 0.017
positive regulation of developmental process GO:0051094 143 0.017
nucleotide metabolic process GO:0009117 161 0.017
eye photoreceptor cell differentiation GO:0001754 145 0.017
regulation of small gtpase mediated signal transduction GO:0051056 93 0.017
regulation of sequestering of calcium ion GO:0051282 3 0.017
Zebrafish
localization of cell GO:0051674 257 0.017
Zebrafish
regulation of chromosome organization GO:0033044 64 0.017
regulation of phosphorylation GO:0042325 147 0.017
Human
regulation of gtpase activity GO:0043087 44 0.017
oocyte maturation GO:0001556 3 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.016
regulation of chromatin organization GO:1902275 32 0.016
regulation of cellular component size GO:0032535 98 0.016
Mouse
positive regulation of apoptotic signaling pathway GO:2001235 4 0.016
ribonucleotide catabolic process GO:0009261 109 0.016
camera type eye development GO:0043010 4 0.016
immune system development GO:0002520 57 0.016
positive regulation of gtp catabolic process GO:0033126 43 0.016
activation of cysteine type endopeptidase activity GO:0097202 17 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
protein modification by small protein conjugation GO:0032446 79 0.016
endocytosis GO:0006897 310 0.016
single organism intracellular transport GO:1902582 207 0.016
Zebrafish
convergent extension GO:0060026 2 0.016
Zebrafish
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
positive regulation of protein modification process GO:0031401 58 0.016
regulation of cell development GO:0060284 215 0.016
Mouse
release of sequestered calcium ion into cytosol GO:0051209 1 0.016
Zebrafish
gastrulation GO:0007369 70 0.015
Zebrafish
heterochromatin organization GO:0070828 25 0.015
wnt signaling pathway GO:0016055 98 0.015
Zebrafish Mouse Fly
positive regulation of multicellular organismal process GO:0051240 143 0.015
autophagic cell death GO:0048102 83 0.015
morphogenesis of a branching structure GO:0001763 45 0.015
nucleolus organization GO:0007000 4 0.015
neurological system process GO:0050877 358 0.015
Fly
protein ubiquitination GO:0016567 70 0.015
neural retina development GO:0003407 4 0.015
response to ethanol GO:0045471 59 0.015
purine nucleoside triphosphate metabolic process GO:0009144 119 0.015
nucleosome organization GO:0034728 59 0.015
regulation of wnt signaling pathway GO:0030111 68 0.015
regulation of protein phosphorylation GO:0001932 64 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
Human
regulation of molecular function GO:0065009 217 0.014
organic substance transport GO:0071702 257 0.014
axis elongation GO:0003401 3 0.014
Zebrafish
regulation of hydrolase activity GO:0051336 97 0.014
epithelial tube morphogenesis GO:0060562 88 0.014
single organism catabolic process GO:0044712 228 0.014
sensory organ morphogenesis GO:0090596 260 0.014
purine ribonucleoside catabolic process GO:0046130 112 0.014
motor neuron axon guidance GO:0008045 58 0.014
Fly
small molecule metabolic process GO:0044281 305 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
protein modification process GO:0036211 438 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.014
chromosome organization GO:0051276 360 0.014
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.013
peptidyl amino acid modification GO:0018193 105 0.013
golgi organization GO:0007030 66 0.013
cytokinesis GO:0000910 90 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
Mouse
vesicle mediated transport GO:0016192 381 0.013
positive regulation of gtpase activity GO:0043547 43 0.013
mitotic spindle organization GO:0007052 220 0.013
positive regulation of cell death GO:0010942 69 0.013
actin filament bundle assembly GO:0051017 26 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
compound eye photoreceptor development GO:0042051 78 0.013
regulation of protein modification process GO:0031399 112 0.013
cellularization GO:0007349 90 0.013
cell division GO:0051301 248 0.013
Worm
signal transduction by phosphorylation GO:0023014 107 0.013
Human
wound healing GO:0042060 75 0.013
skeletal muscle organ development GO:0060538 48 0.013
microtubule organizing center organization GO:0031023 168 0.013
regulation of cell fate commitment GO:0010453 29 0.012
regulation of heart induction GO:0090381 3 0.012
mesodermal cell migration GO:0008078 7 0.012
positive regulation of catabolic process GO:0009896 105 0.012
regulation of cell fate specification GO:0042659 27 0.012
cellular ketone metabolic process GO:0042180 24 0.012
regulation of chromatin modification GO:1903308 28 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
regulation of localization GO:0032879 275 0.012
Zebrafish Mouse
positive regulation of protein metabolic process GO:0051247 128 0.012
response to bacterium GO:0009617 198 0.012
immune system process GO:0002376 347 0.012
cellular amine metabolic process GO:0044106 12 0.012
kidney development GO:0001822 3 0.012
limb morphogenesis GO:0035108 1 0.012
sex comb development GO:0045498 8 0.012
positive regulation of cell migration GO:0030335 2 0.012
protein heterooligomerization GO:0051291 4 0.012
proteolysis GO:0006508 192 0.012
regulation of defense response GO:0031347 102 0.012
immune response GO:0006955 246 0.011
spindle assembly involved in female meiosis GO:0007056 14 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
regulation of ras gtpase activity GO:0032318 38 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.011
axon midline choice point recognition GO:0016199 26 0.011
Fly
detection of stimulus involved in sensory perception GO:0050906 92 0.011
learning or memory GO:0007611 141 0.011
Fly
cellular response to oxygen containing compound GO:1901701 79 0.011
macromolecule catabolic process GO:0009057 161 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
innate immune response GO:0045087 144 0.011
telencephalon development GO:0021537 2 0.011
Mouse
anterior posterior axis specification embryo GO:0008595 103 0.011
axon development GO:0061564 297 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
positive regulation of signaling GO:0023056 243 0.011
Human
purine nucleoside triphosphate catabolic process GO:0009146 108 0.010
digestive system development GO:0055123 149 0.010
Zebrafish
positive regulation of phosphate metabolic process GO:0045937 139 0.010
Human
protein processing GO:0016485 68 0.010
apoptotic process GO:0006915 159 0.010
regulation of imaginal disc derived wing size GO:0044719 20 0.010
gastrulation with mouth forming first GO:0001703 36 0.010
eye photoreceptor cell development GO:0042462 81 0.010
larval development GO:0002164 104 0.010
Worm
regulation of response to external stimulus GO:0032101 115 0.010
Mouse
organophosphate catabolic process GO:0046434 112 0.010
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.010
Mouse

dnt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.012
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010