Drosophila melanogaster

88 known processes

wds (Dmel_CG17437)

will die slowly

(Aliases: zw8,l(1)zw8,l(1)16-94,Dmel\CG17437,CG17437,zw-8,l(1)G0251,WDS,EG:BACR25B3.7,l(1)3Ad,Wds)

wds biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
histone modification GO:0016570 106 0.919
protein acetylation GO:0006473 39 0.914
covalent chromatin modification GO:0016569 106 0.912
peptidyl lysine modification GO:0018205 57 0.841
chromatin organization GO:0006325 207 0.825
histone h4 acetylation GO:0043967 13 0.779
Human
positive regulation of rna metabolic process GO:0051254 271 0.759
Mouse
histone acetylation GO:0016573 38 0.685
protein modification process GO:0036211 438 0.658
positive regulation of gene expression GO:0010628 290 0.608
Mouse
internal peptidyl lysine acetylation GO:0018393 38 0.588
protein acylation GO:0043543 42 0.559
positive regulation of transcription dna templated GO:0045893 266 0.538
Mouse
chromatin remodeling GO:0006338 72 0.475
enzyme linked receptor protein signaling pathway GO:0007167 179 0.444
imaginal disc derived appendage development GO:0048737 399 0.443
chromatin modification GO:0016568 147 0.437
negative regulation of cellular metabolic process GO:0031324 382 0.407
wing disc morphogenesis GO:0007472 344 0.357
positive regulation of rna biosynthetic process GO:1902680 266 0.347
Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.338
Mouse
regionalization GO:0003002 416 0.329
positive regulation of biosynthetic process GO:0009891 316 0.320
Mouse
peptidyl amino acid modification GO:0018193 105 0.304
chromosome organization GO:0051276 360 0.304
cellular protein modification process GO:0006464 438 0.293
cellular component assembly involved in morphogenesis GO:0010927 151 0.288
peptidyl lysine acetylation GO:0018394 39 0.275
appendage morphogenesis GO:0035107 397 0.206
alternative mrna splicing via spliceosome GO:0000380 60 0.190
negative regulation of rna metabolic process GO:0051253 251 0.187
internal protein amino acid acetylation GO:0006475 38 0.183
negative regulation of cell cycle process GO:0010948 109 0.183
compound eye photoreceptor cell differentiation GO:0001751 140 0.181
positive regulation of nucleic acid templated transcription GO:1903508 266 0.180
Mouse
negative regulation of gene expression GO:0010629 387 0.166
vesicle mediated transport GO:0016192 381 0.166
cellular amino acid metabolic process GO:0006520 61 0.154
positive regulation of cellular biosynthetic process GO:0031328 316 0.150
Mouse
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.150
cellular response to dna damage stimulus GO:0006974 223 0.150
intracellular signal transduction GO:0035556 300 0.149
imaginal disc derived wing morphogenesis GO:0007476 337 0.148
transcription from rna polymerase ii promoter GO:0006366 368 0.147
Mouse
establishment of localization in cell GO:0051649 402 0.145
dendrite morphogenesis GO:0048813 199 0.142
negative regulation of cellular biosynthetic process GO:0031327 277 0.141
muscle cell development GO:0055001 50 0.139
open tracheal system development GO:0007424 204 0.139
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.137
regulation of protein modification process GO:0031399 112 0.135
stem cell differentiation GO:0048863 117 0.134
organelle assembly GO:0070925 198 0.133
post embryonic appendage morphogenesis GO:0035120 385 0.131
muscle cell differentiation GO:0042692 103 0.128
methylation GO:0032259 47 0.127
imaginal disc derived appendage morphogenesis GO:0035114 395 0.122
stem cell maintenance GO:0019827 67 0.118
dendrite development GO:0016358 204 0.117
response to abiotic stimulus GO:0009628 341 0.115
molting cycle GO:0042303 56 0.115
axon development GO:0061564 297 0.114
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.111
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.111
Mouse
rna splicing GO:0008380 83 0.109
regulation of multicellular organismal development GO:2000026 414 0.102
Worm
regulation of cellular amine metabolic process GO:0033238 3 0.101
appendage development GO:0048736 401 0.101
cell motility GO:0048870 251 0.094
Worm
actin cytoskeleton organization GO:0030036 206 0.092
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.086
Mouse
regulation of nervous system development GO:0051960 248 0.086
regulation of cellular protein metabolic process GO:0032268 243 0.085
proteolysis GO:0006508 192 0.084
eye photoreceptor cell differentiation GO:0001754 145 0.080
cytoplasmic transport GO:0016482 130 0.079
regulation of cellular ketone metabolic process GO:0010565 3 0.079
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.078
body morphogenesis GO:0010171 2 0.076
immune response GO:0006955 246 0.074
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.074
Mouse
spermatogenesis GO:0007283 200 0.071
axonogenesis GO:0007409 290 0.070
dna biosynthetic process GO:0071897 24 0.069
imaginal disc derived wing vein specification GO:0007474 48 0.069
response to radiation GO:0009314 155 0.068
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.068
striated muscle cell development GO:0055002 50 0.067
neuronal stem cell maintenance GO:0097150 4 0.066
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.064
positive regulation of signaling GO:0023056 243 0.063
central nervous system development GO:0007417 201 0.061
regulation of cellular amino acid metabolic process GO:0006521 0 0.060
photoreceptor cell differentiation GO:0046530 170 0.058
regulation of rna splicing GO:0043484 69 0.056
intracellular transport GO:0046907 228 0.055
histone h3 acetylation GO:0043966 11 0.051
Human
establishment of protein localization GO:0045184 163 0.050
regulation of small gtpase mediated signal transduction GO:0051056 93 0.050
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.048
phosphorylation GO:0016310 294 0.047
negative regulation of developmental process GO:0051093 201 0.047
Worm
cellular response to chemical stimulus GO:0070887 199 0.047
amine metabolic process GO:0009308 12 0.046
regulation of cell differentiation GO:0045595 302 0.046
regulation of erbb signaling pathway GO:1901184 42 0.046
nucleosome organization GO:0034728 59 0.044
mrna splicing via spliceosome GO:0000398 73 0.043
muscle structure development GO:0061061 224 0.041
dna damage checkpoint GO:0000077 78 0.040
negative regulation of cell cycle GO:0045786 116 0.040
rna processing GO:0006396 147 0.040
actomyosin structure organization GO:0031032 56 0.039
regulation of protein metabolic process GO:0051246 256 0.039
transmembrane transport GO:0055085 139 0.039
cellular amine metabolic process GO:0044106 12 0.038
immune system process GO:0002376 347 0.037
phagocytosis GO:0006909 215 0.037
myofibril assembly GO:0030239 36 0.037
modification dependent macromolecule catabolic process GO:0043632 79 0.036
single organism intracellular transport GO:1902582 207 0.036
postreplication repair GO:0006301 2 0.036
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.035
Mouse
response to endogenous stimulus GO:0009719 119 0.035
epidermal growth factor receptor signaling pathway GO:0007173 58 0.034
positive regulation of signal transduction GO:0009967 223 0.034
dorsal ventral pattern formation GO:0009953 133 0.033
organic acid metabolic process GO:0006082 103 0.033
anterior posterior axis specification GO:0009948 109 0.032
regulation of bmp signaling pathway GO:0030510 23 0.032
regulation of immune response GO:0050776 118 0.032
cellular protein localization GO:0034613 160 0.032
respiratory system development GO:0060541 213 0.031
neuron fate commitment GO:0048663 50 0.030
nucleocytoplasmic transport GO:0006913 72 0.029
axon guidance GO:0007411 233 0.028
protein catabolic process GO:0030163 101 0.028
defense response GO:0006952 300 0.028
regulation of mitotic cell cycle phase transition GO:1901990 130 0.028
spindle organization GO:0007051 253 0.028
inter male aggressive behavior GO:0002121 60 0.028
proteasomal protein catabolic process GO:0010498 59 0.028
mrna metabolic process GO:0016071 124 0.028
regulation of immune system process GO:0002682 176 0.027
positive regulation of cell communication GO:0010647 250 0.027
tube morphogenesis GO:0035239 191 0.026
regulation of gene expression epigenetic GO:0040029 128 0.026
male gamete generation GO:0048232 201 0.026
regulation of mrna splicing via spliceosome GO:0048024 64 0.025
carboxylic acid metabolic process GO:0019752 92 0.025
erbb signaling pathway GO:0038127 58 0.025
forebrain development GO:0030900 2 0.025
regulation of phosphorylation GO:0042325 147 0.025
regulation of phosphorus metabolic process GO:0051174 210 0.024
embryo development ending in birth or egg hatching GO:0009792 152 0.024
macromolecule methylation GO:0043414 45 0.024
regulation of intracellular signal transduction GO:1902531 236 0.022
neurological system process GO:0050877 358 0.021
negative regulation of cell differentiation GO:0045596 143 0.021
axis specification GO:0009798 167 0.021
stem cell development GO:0048864 79 0.021
cell fate specification GO:0001708 71 0.021
organonitrogen compound metabolic process GO:1901564 318 0.021
cellular macromolecule catabolic process GO:0044265 136 0.021
head development GO:0060322 135 0.020
germ line stem cell maintenance GO:0030718 50 0.020
positive regulation of immune response GO:0050778 63 0.020
actin filament based process GO:0030029 220 0.020
nuclear export GO:0051168 24 0.020
response to alcohol GO:0097305 95 0.020
translesion synthesis GO:0019985 2 0.020
positive regulation of response to stimulus GO:0048584 323 0.019
negative regulation of nucleic acid templated transcription GO:1903507 240 0.019
regulation of notch signaling pathway GO:0008593 100 0.019
negative regulation of signal transduction GO:0009968 206 0.019
protein alkylation GO:0008213 43 0.019
spindle assembly involved in mitosis GO:0090307 50 0.019
regulation of transport GO:0051049 181 0.019
striated muscle cell differentiation GO:0051146 90 0.019
response to organic substance GO:0010033 284 0.019
olfactory behavior GO:0042048 97 0.019
nuclear transport GO:0051169 72 0.018
positive regulation of immune system process GO:0002684 68 0.018
protein transport GO:0015031 155 0.018
negative regulation of protein modification process GO:0031400 29 0.018
protein localization to organelle GO:0033365 82 0.018
organic substance transport GO:0071702 257 0.018
embryonic pattern specification GO:0009880 174 0.018
negative regulation of protein metabolic process GO:0051248 85 0.018
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.018
protein complex assembly GO:0006461 200 0.018
positive regulation of histone deacetylation GO:0031065 2 0.018
regulation of response to stress GO:0080134 200 0.018
cell death GO:0008219 279 0.017
Worm
protein targeting to nucleus GO:0044744 51 0.017
endocytosis GO:0006897 310 0.017
defense response to other organism GO:0098542 225 0.017
apoptotic process GO:0006915 159 0.017
Worm
regulation of phosphatase activity GO:0010921 3 0.016
negative regulation of rna biosynthetic process GO:1902679 240 0.016
gtp metabolic process GO:0046039 72 0.016
oxoacid metabolic process GO:0043436 103 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.016
developmental maturation GO:0021700 172 0.016
hematopoietic progenitor cell differentiation GO:0002244 1 0.016
macromolecule catabolic process GO:0009057 161 0.016
protein maturation GO:0051604 71 0.015
ubiquitin dependent protein catabolic process GO:0006511 78 0.015
regulation of nucleocytoplasmic transport GO:0046822 35 0.015
rna splicing via transesterification reactions GO:0000375 73 0.015
nucleobase containing compound transport GO:0015931 56 0.015
organelle localization GO:0051640 148 0.015
aging GO:0007568 143 0.015
Worm
regulation of mrna metabolic process GO:1903311 72 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
single organism cellular localization GO:1902580 180 0.014
mitotic cytokinesis GO:0000281 50 0.014
larval development GO:0002164 104 0.014
Worm
establishment or maintenance of cell polarity GO:0007163 167 0.014
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
negative regulation of transcription dna templated GO:0045892 237 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
mrna processing GO:0006397 104 0.013
small molecule metabolic process GO:0044281 305 0.013
Mouse
positive regulation of protein deacetylation GO:0090312 2 0.013
regulation of molecular function GO:0065009 217 0.013
histone deubiquitination GO:0016578 8 0.013
neuron recognition GO:0008038 101 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
positive regulation of cellular component organization GO:0051130 156 0.013
cell cycle checkpoint GO:0000075 95 0.013
compound eye development GO:0048749 307 0.013
regulation of neuron differentiation GO:0045664 103 0.013
protein processing GO:0016485 68 0.013
intracellular protein transport GO:0006886 104 0.013
mitochondrion organization GO:0007005 65 0.013
cellular macromolecule localization GO:0070727 220 0.012
neuron projection guidance GO:0097485 241 0.012
regulation of hemocyte proliferation GO:0035206 37 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
bmp signaling pathway GO:0030509 27 0.012
protein phosphorylation GO:0006468 169 0.012
cell migration GO:0016477 238 0.012
Worm
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
oocyte development GO:0048599 124 0.011
exocrine system development GO:0035272 162 0.011
response to biotic stimulus GO:0009607 294 0.011
regulation of meiosis GO:0040020 3 0.011
eye photoreceptor cell fate commitment GO:0042706 37 0.011
salivary gland development GO:0007431 162 0.011
regulation of cytoplasmic transport GO:1903649 47 0.011
positive regulation of notch signaling pathway GO:0045747 34 0.011
segmentation GO:0035282 207 0.011
dna metabolic process GO:0006259 227 0.011
ras protein signal transduction GO:0007265 88 0.011
hindbrain development GO:0030902 2 0.011
anatomical structure homeostasis GO:0060249 97 0.011
protein targeting GO:0006605 64 0.010
notch signaling pathway GO:0007219 120 0.010
cell maturation GO:0048469 144 0.010
striated muscle myosin thick filament assembly GO:0071688 3 0.010
regulation of phosphate metabolic process GO:0019220 210 0.010
chemosensory behavior GO:0007635 106 0.010
cellular protein catabolic process GO:0044257 83 0.010

wds disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013