Drosophila melanogaster

156 known processes

RhoGAP18B (Dmel_CG42274)

CG42274 gene product from transcript CG42274-RC

(Aliases: Dmel\CG42274,CG7481,5-131,CG42274,Dmel_CG7481,Dmel_CG7502,CG7531,CG7502,CG17015,whir)

RhoGAP18B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory perception of smell GO:0007608 80 0.579
chemosensory behavior GO:0007635 106 0.570
olfactory behavior GO:0042048 97 0.492
sensory perception of chemical stimulus GO:0007606 116 0.483
sensory perception GO:0007600 196 0.227
single organism behavior GO:0044708 391 0.198
imaginal disc derived appendage morphogenesis GO:0035114 395 0.164
detection of chemical stimulus involved in sensory perception of smell GO:0050911 50 0.153
detection of stimulus GO:0051606 156 0.142
imaginal disc derived appendage development GO:0048737 399 0.135
neurological system process GO:0050877 358 0.125
detection of chemical stimulus GO:0009593 93 0.124
post embryonic appendage morphogenesis GO:0035120 385 0.122
appendage morphogenesis GO:0035107 397 0.107
wing disc morphogenesis GO:0007472 344 0.097
appendage development GO:0048736 401 0.088
adult behavior GO:0030534 137 0.084
response to ethanol GO:0045471 59 0.082
regulation of cellular amine metabolic process GO:0033238 3 0.077
detection of stimulus involved in sensory perception GO:0050906 92 0.072
small molecule metabolic process GO:0044281 305 0.066
positive regulation of cell communication GO:0010647 250 0.063
response to abiotic stimulus GO:0009628 341 0.060
imaginal disc derived wing morphogenesis GO:0007476 337 0.060
single organism biosynthetic process GO:0044711 206 0.056
response to organic substance GO:0010033 284 0.049
ovarian follicle cell development GO:0030707 248 0.049
protein heterooligomerization GO:0051291 4 0.048
cellular amino acid metabolic process GO:0006520 61 0.047
organonitrogen compound metabolic process GO:1901564 318 0.046
immune response GO:0006955 246 0.046
lateral inhibition GO:0046331 206 0.045
epithelial cell differentiation GO:0030855 322 0.045
regulation of cellular ketone metabolic process GO:0010565 3 0.043
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.042
regulation of phosphorylation GO:0042325 147 0.042
ras protein signal transduction GO:0007265 88 0.041
positive regulation of signaling GO:0023056 243 0.041
cell cell signaling involved in cell fate commitment GO:0045168 210 0.041
behavioral response to ethanol GO:0048149 49 0.040
immune system process GO:0002376 347 0.039
regulation of intracellular signal transduction GO:1902531 236 0.039
response to alcohol GO:0097305 95 0.039
response to radiation GO:0009314 155 0.039
regulation of phosphate metabolic process GO:0019220 210 0.039
intracellular signal transduction GO:0035556 300 0.038
cellular ketone metabolic process GO:0042180 24 0.038
insecticide metabolic process GO:0017143 2 0.037
epithelial cell migration GO:0010631 148 0.037
polyol biosynthetic process GO:0046173 3 0.037
regulation of phosphorus metabolic process GO:0051174 210 0.036
vesicle mediated transport GO:0016192 381 0.035
response to mercury ion GO:0046689 3 0.035
positive regulation of signal transduction GO:0009967 223 0.033
regulation of cell differentiation GO:0045595 302 0.033
organophosphate metabolic process GO:0019637 195 0.033
actin cytoskeleton organization GO:0030036 206 0.033
chemical homeostasis GO:0048878 92 0.032
negative regulation of cellular component organization GO:0051129 108 0.032
tissue migration GO:0090130 155 0.032
single organism catabolic process GO:0044712 228 0.031
carbohydrate derivative metabolic process GO:1901135 217 0.031
macromolecular complex assembly GO:0065003 256 0.031
amine metabolic process GO:0009308 12 0.030
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.029
organic hydroxy compound metabolic process GO:1901615 83 0.029
cellular amine metabolic process GO:0044106 12 0.029
epithelium migration GO:0090132 148 0.028
protein complex biogenesis GO:0070271 201 0.027
cell death GO:0008219 279 0.027
negative regulation of gene expression GO:0010629 387 0.027
oxoacid metabolic process GO:0043436 103 0.027
ameboidal type cell migration GO:0001667 151 0.027
protein complex assembly GO:0006461 200 0.027
homeostatic process GO:0042592 199 0.027
nucleotide metabolic process GO:0009117 161 0.026
negative regulation of cellular metabolic process GO:0031324 382 0.026
endocytosis GO:0006897 310 0.026
neuromuscular junction development GO:0007528 149 0.026
nucleoside phosphate metabolic process GO:0006753 162 0.026
spermatogenesis GO:0007283 200 0.026
response to light stimulus GO:0009416 124 0.026
cellular macromolecule catabolic process GO:0044265 136 0.025
organic substance catabolic process GO:1901575 308 0.025
protein phosphorylation GO:0006468 169 0.025
phosphorylation GO:0016310 294 0.025
cellular homeostasis GO:0019725 80 0.025
regionalization GO:0003002 416 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.024
regulation of organelle organization GO:0033043 196 0.024
response to external biotic stimulus GO:0043207 293 0.024
catabolic process GO:0009056 409 0.023
spermatid differentiation GO:0048515 114 0.023
response to oxidative stress GO:0006979 86 0.023
positive regulation of rho gtpase activity GO:0032321 19 0.022
epithelial cell development GO:0002064 274 0.022
regulation of cellular localization GO:0060341 136 0.022
purine containing compound metabolic process GO:0072521 155 0.022
small gtpase mediated signal transduction GO:0007264 88 0.022
purine ribonucleoside metabolic process GO:0046128 127 0.022
locomotory behavior GO:0007626 176 0.022
regulation of cytoskeleton organization GO:0051493 89 0.022
lipid metabolic process GO:0006629 121 0.022
aging GO:0007568 143 0.022
positive regulation of response to stimulus GO:0048584 323 0.022
rna processing GO:0006396 147 0.022
nucleobase containing small molecule metabolic process GO:0055086 174 0.021
g protein coupled receptor signaling pathway GO:0007186 136 0.021
carboxylic acid metabolic process GO:0019752 92 0.021
phagocytosis GO:0006909 215 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.021
metal ion transport GO:0030001 74 0.021
cellular protein modification process GO:0006464 438 0.020
regulation of small gtpase mediated signal transduction GO:0051056 93 0.020
lipid homeostasis GO:0055088 33 0.020
defense response GO:0006952 300 0.020
rho protein signal transduction GO:0007266 14 0.020
columnar cuboidal epithelial cell development GO:0002066 249 0.020
regulation of growth GO:0040008 233 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.020
regulation of transport GO:0051049 181 0.019
negative regulation of response to stimulus GO:0048585 258 0.018
regulation of ras protein signal transduction GO:0046578 93 0.018
purine nucleotide catabolic process GO:0006195 109 0.018
mapk cascade GO:0000165 107 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.018
detection of chemical stimulus involved in sensory perception GO:0050907 75 0.018
regulation of multicellular organismal development GO:2000026 414 0.018
ribonucleotide metabolic process GO:0009259 145 0.018
dendrite morphogenesis GO:0048813 199 0.018
ethanolamine containing compound metabolic process GO:0042439 4 0.018
regulation of protein modification process GO:0031399 112 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
neurotransmitter metabolic process GO:0042133 2 0.018
purine containing compound catabolic process GO:0072523 112 0.018
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
response to oxygen containing compound GO:1901700 200 0.017
programmed cell death GO:0012501 257 0.017
regulation of response to external stimulus GO:0032101 115 0.017
regulation of immune system process GO:0002682 176 0.017
steroid catabolic process GO:0006706 1 0.017
nucleobase containing compound catabolic process GO:0034655 165 0.017
chromosome organization GO:0051276 360 0.017
response to other organism GO:0051707 293 0.017
positive regulation of cellular component biogenesis GO:0044089 80 0.017
regulation of cellular component biogenesis GO:0044087 201 0.017
lauric acid metabolic process GO:0048252 1 0.017
protein modification process GO:0036211 438 0.017
eye development GO:0001654 323 0.017
compound eye development GO:0048749 307 0.017
organonitrogen compound catabolic process GO:1901565 128 0.017
positive regulation of gtp catabolic process GO:0033126 43 0.017
embryo development ending in birth or egg hatching GO:0009792 152 0.017
purine ribonucleotide metabolic process GO:0009150 145 0.017
cellular response to dna damage stimulus GO:0006974 223 0.017
positive regulation of intracellular signal transduction GO:1902533 116 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
growth GO:0040007 359 0.016
negative regulation of signaling GO:0023057 219 0.016
eye morphogenesis GO:0048592 260 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
ovarian follicle cell migration GO:0007297 121 0.016
regulation of molecular function GO:0065009 217 0.016
organic hydroxy compound biosynthetic process GO:1901617 21 0.016
acetylcholine metabolic process GO:0008291 2 0.016
regulation of cell projection organization GO:0031344 92 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
developmental growth GO:0048589 280 0.015
regulation of g protein coupled receptor protein signaling pathway GO:0008277 23 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
protein localization GO:0008104 284 0.015
regulation of catalytic activity GO:0050790 185 0.015
apoptotic process GO:0006915 159 0.015
cellular ion homeostasis GO:0006873 39 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
aromatic compound catabolic process GO:0019439 166 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
adult locomotory behavior GO:0008344 76 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
innate immune response GO:0045087 144 0.014
ribonucleotide catabolic process GO:0009261 109 0.014
regulation of developmental growth GO:0048638 174 0.014
spindle organization GO:0007051 253 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.014
regulation of hormone levels GO:0010817 40 0.014
cell proliferation GO:0008283 299 0.014
regulation of localization GO:0032879 275 0.014
multicellular organismal aging GO:0010259 140 0.014
nuclear division GO:0000280 332 0.014
organic cyclic compound catabolic process GO:1901361 168 0.013
rna splicing GO:0008380 83 0.013
digestive tract development GO:0048565 149 0.013
response to temperature stimulus GO:0009266 106 0.013
leg disc development GO:0035218 92 0.013
negative regulation of cell communication GO:0010648 223 0.013
vitamin biosynthetic process GO:0009110 1 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
positive regulation of jun kinase activity GO:0043507 4 0.013
acetate ester metabolic process GO:1900619 2 0.013
cell migration GO:0016477 238 0.013
membrane depolarization GO:0051899 4 0.013
nucleoside triphosphate catabolic process GO:0009143 108 0.013
positive regulation of rna metabolic process GO:0051254 271 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
anion homeostasis GO:0055081 3 0.013
response to endogenous stimulus GO:0009719 119 0.013
organic acid metabolic process GO:0006082 103 0.013
protein localization to organelle GO:0033365 82 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
response to heat GO:0009408 63 0.012
regulation of nucleotide metabolic process GO:0006140 62 0.012
alcohol metabolic process GO:0006066 25 0.012
tube development GO:0035295 244 0.012
nucleoside catabolic process GO:0009164 112 0.012
positive regulation of transport GO:0051050 92 0.012
embryonic morphogenesis GO:0048598 206 0.012
macromolecule catabolic process GO:0009057 161 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
small molecule biosynthetic process GO:0044283 37 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
regulation of nervous system development GO:0051960 248 0.012
cellular response to organic substance GO:0071310 132 0.012
endomembrane system organization GO:0010256 119 0.012
skin development GO:0043588 65 0.012
response to monosaccharide GO:0034284 4 0.012
regulation of neuron projection development GO:0010975 69 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
fat soluble vitamin biosynthetic process GO:0042362 1 0.012
negative regulation of intracellular signal transduction GO:1902532 57 0.012
response to glucose GO:0009749 2 0.011
compound eye morphogenesis GO:0001745 249 0.011
imaginal disc derived leg morphogenesis GO:0007480 80 0.011
mrna processing GO:0006397 104 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.011
peptidyl amino acid modification GO:0018193 105 0.011
lipid biosynthetic process GO:0008610 46 0.011
cation homeostasis GO:0055080 51 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
stem cell differentiation GO:0048863 117 0.011
positive regulation of macromolecule metabolic process GO:0010604 405 0.011
actin filament based process GO:0030029 220 0.011
regulation of protein kinase activity GO:0045859 51 0.011
regulation of protein metabolic process GO:0051246 256 0.011
cellular response to mechanical stimulus GO:0071260 2 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
death GO:0016265 284 0.011
response to copper ion GO:0046688 4 0.011
negative regulation of transcription dna templated GO:0045892 237 0.011
synapse organization GO:0050808 196 0.011
chromosome segregation GO:0007059 157 0.011
response to inorganic substance GO:0010035 44 0.011
positive regulation of cell migration GO:0030335 2 0.011
sterol homeostasis GO:0055092 4 0.011
cellular lipid metabolic process GO:0044255 83 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
digestive system development GO:0055123 149 0.011
positive regulation of protein modification process GO:0031401 58 0.011
regulation of mapk cascade GO:0043408 92 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
positive regulation of cell motility GO:2000147 3 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
organelle fission GO:0048285 340 0.010
vitamin metabolic process GO:0006766 2 0.010
regulation of epithelial cell proliferation GO:0050678 4 0.010
cell motility GO:0048870 251 0.010
response to organophosphorus GO:0046683 2 0.010
positive regulation of ras gtpase activity GO:0032320 36 0.010
negative regulation of nucleic acid templated transcription GO:1903507 240 0.010
regulation of cell size GO:0008361 63 0.010
body morphogenesis GO:0010171 2 0.010
feeding behavior GO:0007631 50 0.010
cortical cytoskeleton organization GO:0030865 29 0.010
xenobiotic catabolic process GO:0042178 1 0.010
regulation of response to stress GO:0080134 200 0.010
positive regulation of mapk cascade GO:0043410 63 0.010

RhoGAP18B disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.050
disease of anatomical entity DOID:7 0 0.034
hypertension DOID:10763 0 0.023
artery disease DOID:0050828 0 0.023
vascular disease DOID:178 0 0.023
cardiovascular system disease DOID:1287 0 0.023
carbohydrate metabolism disease DOID:0050013 0 0.018
acquired metabolic disease DOID:0060158 0 0.018
glucose metabolism disease DOID:4194 0 0.018
essential hypertension DOID:10825 0 0.012