Drosophila melanogaster

81 known processes

CHES-1-like (Dmel_CG12690)

Checkpoint suppressor homologue

(Aliases: FoxN,anon-EST:Posey7,Ches-1-like,ches1,Dmches-1,CG12690,Dmel\CG12690)

CHES-1-like biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
renal filtration GO:0097205 7 0.112
positive regulation of macromolecule metabolic process GO:0010604 405 0.097
appendage morphogenesis GO:0035107 397 0.081
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.077
negative regulation of gene expression GO:0010629 387 0.075
imaginal disc derived appendage development GO:0048737 399 0.069
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.068
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.064
central nervous system development GO:0007417 201 0.061
appendage development GO:0048736 401 0.053
telencephalon development GO:0021537 2 0.051
positive regulation of signaling GO:0023056 243 0.049
negative regulation of cellular biosynthetic process GO:0031327 277 0.049
post embryonic appendage morphogenesis GO:0035120 385 0.047
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.046
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.045
catabolic process GO:0009056 409 0.044
positive regulation of transcription dna templated GO:0045893 266 0.044
chromatin organization GO:0006325 207 0.044
muscle organ development GO:0007517 127 0.044
establishment of localization in cell GO:0051649 402 0.044
protein modification process GO:0036211 438 0.044
negative regulation of cellular metabolic process GO:0031324 382 0.043
chromosome organization GO:0051276 360 0.042
imaginal disc derived appendage morphogenesis GO:0035114 395 0.042
camera type eye morphogenesis GO:0048593 2 0.042
positive regulation of response to stimulus GO:0048584 323 0.041
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.041
small molecule metabolic process GO:0044281 305 0.041
morphogenesis of an epithelium GO:0002009 276 0.040
positive regulation of signal transduction GO:0009967 223 0.039
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.039
transcription from rna polymerase ii promoter GO:0006366 368 0.038
antimicrobial humoral response GO:0019730 99 0.038
cellular catabolic process GO:0044248 372 0.037
salivary gland development GO:0007431 162 0.036
negative regulation of rna metabolic process GO:0051253 251 0.035
cell cell signaling involved in cell fate commitment GO:0045168 210 0.035
positive regulation of catabolic process GO:0009896 105 0.035
positive regulation of multicellular organismal process GO:0051240 143 0.035
aromatic compound catabolic process GO:0019439 166 0.035
regulation of cell cycle GO:0051726 291 0.034
death GO:0016265 284 0.034
renal system process GO:0003014 12 0.034
tube development GO:0035295 244 0.034
heterocycle catabolic process GO:0046700 166 0.034
carbohydrate derivative metabolic process GO:1901135 217 0.034
negative regulation of biosynthetic process GO:0009890 277 0.033
wing disc morphogenesis GO:0007472 344 0.032
camera type eye development GO:0043010 4 0.032
negative regulation of programmed cell death GO:0043069 72 0.032
cellular protein modification process GO:0006464 438 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.031
positive regulation of rna metabolic process GO:0051254 271 0.031
response to organic substance GO:0010033 284 0.031
growth GO:0040007 359 0.031
regulation of catalytic activity GO:0050790 185 0.031
positive regulation of cellular biosynthetic process GO:0031328 316 0.030
cell death GO:0008219 279 0.030
regulation of multicellular organismal development GO:2000026 414 0.030
positive regulation of rna biosynthetic process GO:1902680 266 0.030
regulation of cellular protein metabolic process GO:0032268 243 0.029
imaginal disc derived wing morphogenesis GO:0007476 337 0.029
cellular response to dna damage stimulus GO:0006974 223 0.029
positive regulation of hydrolase activity GO:0051345 78 0.029
proteolysis GO:0006508 192 0.029
regulation of cell proliferation GO:0042127 163 0.029
regulation of molecular function GO:0065009 217 0.028
response to other organism GO:0051707 293 0.028
positive regulation of cell communication GO:0010647 250 0.028
positive regulation of nucleic acid templated transcription GO:1903508 266 0.028
cellular protein localization GO:0034613 160 0.028
regulation of phosphorus metabolic process GO:0051174 210 0.028
positive regulation of developmental process GO:0051094 143 0.028
muscle structure development GO:0061061 224 0.027
organic substance catabolic process GO:1901575 308 0.026
intracellular transport GO:0046907 228 0.026
phosphorylation GO:0016310 294 0.026
gland morphogenesis GO:0022612 145 0.026
regulation of anatomical structure morphogenesis GO:0022603 242 0.025
humoral immune response GO:0006959 117 0.025
intracellular signal transduction GO:0035556 300 0.025
response to abiotic stimulus GO:0009628 341 0.025
nucleobase containing compound catabolic process GO:0034655 165 0.025
regulation of gene expression epigenetic GO:0040029 128 0.025
negative regulation of nucleic acid templated transcription GO:1903507 240 0.025
chromatin modification GO:0016568 147 0.024
forebrain development GO:0030900 2 0.024
negative regulation of rna biosynthetic process GO:1902679 240 0.024
connective tissue development GO:0061448 3 0.024
regulation of phosphate metabolic process GO:0019220 210 0.024
positive regulation of molecular function GO:0044093 136 0.024
protein catabolic process GO:0030163 101 0.024
rna processing GO:0006396 147 0.024
golgi organization GO:0007030 66 0.023
regulation of mitotic cell cycle GO:0007346 190 0.023
nucleobase containing small molecule metabolic process GO:0055086 174 0.023
endocytosis GO:0006897 310 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.023
phagocytosis GO:0006909 215 0.023
endomembrane system organization GO:0010256 119 0.023
response to biotic stimulus GO:0009607 294 0.022
protein transport GO:0015031 155 0.022
macromolecule catabolic process GO:0009057 161 0.022
heart development GO:0007507 82 0.022
regulation of catabolic process GO:0009894 170 0.022
positive regulation of gene expression GO:0010628 290 0.022
establishment of protein localization GO:0045184 163 0.022
tube morphogenesis GO:0035239 191 0.022
purine nucleotide catabolic process GO:0006195 109 0.022
developmental programmed cell death GO:0010623 138 0.022
regulation of cell cycle process GO:0010564 181 0.022
developmental growth GO:0048589 280 0.022
cell proliferation GO:0008283 299 0.022
single organism intracellular transport GO:1902582 207 0.022
positive regulation of catalytic activity GO:0043085 118 0.021
mesenchymal cell development GO:0014031 1 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
immune response GO:0006955 246 0.021
eye morphogenesis GO:0048592 260 0.021
dorsal ventral pattern formation GO:0009953 133 0.021
negative regulation of transcription dna templated GO:0045892 237 0.021
negative regulation of developmental process GO:0051093 201 0.021
negative regulation of cell death GO:0060548 81 0.020
nuclear transport GO:0051169 72 0.020
dna damage checkpoint GO:0000077 78 0.020
organonitrogen compound metabolic process GO:1901564 318 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.020
positive regulation of phosphate metabolic process GO:0045937 139 0.020
regulation of cell death GO:0010941 173 0.020
embryo development ending in birth or egg hatching GO:0009792 152 0.020
protein modification by small protein conjugation or removal GO:0070647 106 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
cardiovascular system development GO:0072358 82 0.019
muscle tissue development GO:0060537 30 0.019
negative regulation of cellular component organization GO:0051129 108 0.019
brain development GO:0007420 120 0.019
programmed cell death GO:0012501 257 0.019
embryonic development via the syncytial blastoderm GO:0001700 148 0.019
small gtpase mediated signal transduction GO:0007264 88 0.019
cholesterol homeostasis GO:0042632 3 0.018
mitotic spindle organization GO:0007052 220 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
organelle fission GO:0048285 340 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
limb development GO:0060173 1 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
eye development GO:0001654 323 0.018
positive regulation of developmental growth GO:0048639 62 0.018
regulation of cell differentiation GO:0045595 302 0.018
negative regulation of cell communication GO:0010648 223 0.018
purine nucleotide metabolic process GO:0006163 146 0.018
negative regulation of response to stimulus GO:0048585 258 0.018
neurological system process GO:0050877 358 0.018
dna metabolic process GO:0006259 227 0.017
regulation of notch signaling pathway GO:0008593 100 0.017
organophosphate metabolic process GO:0019637 195 0.017
hindgut morphogenesis GO:0007442 58 0.017
regulation of localization GO:0032879 275 0.017
organic substance transport GO:0071702 257 0.017
cell cycle checkpoint GO:0000075 95 0.017
response to oxygen containing compound GO:1901700 200 0.017
mrna processing GO:0006397 104 0.017
leg disc morphogenesis GO:0007478 80 0.017
segmentation GO:0035282 207 0.017
regulation of protein metabolic process GO:0051246 256 0.017
regionalization GO:0003002 416 0.017
nucleotide catabolic process GO:0009166 109 0.016
digestive tract development GO:0048565 149 0.016
regulation of mitotic cell cycle phase transition GO:1901990 130 0.016
cellular macromolecule catabolic process GO:0044265 136 0.016
tissue morphogenesis GO:0048729 297 0.016
nucleoside triphosphate metabolic process GO:0009141 120 0.016
regulation of muscle organ development GO:0048634 13 0.016
sensory organ morphogenesis GO:0090596 260 0.016
negative regulation of cell differentiation GO:0045596 143 0.016
amine metabolic process GO:0009308 12 0.016
cytoplasmic transport GO:0016482 130 0.016
mesenchymal cell differentiation GO:0048762 1 0.016
response to organic cyclic compound GO:0014070 89 0.016
epithelial cell differentiation GO:0030855 322 0.016
compound eye photoreceptor cell differentiation GO:0001751 140 0.016
regulation of organelle organization GO:0033043 196 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
response to alcohol GO:0097305 95 0.016
cellular response to organic substance GO:0071310 132 0.016
rho protein signal transduction GO:0007266 14 0.016
cellular response to oxygen containing compound GO:1901701 79 0.016
response to external biotic stimulus GO:0043207 293 0.016
nucleoside metabolic process GO:0009116 127 0.015
regulation of hydrolase activity GO:0051336 97 0.015
protein localization GO:0008104 284 0.015
positive regulation of cellular catabolic process GO:0031331 95 0.015
regulation of phosphorylation GO:0042325 147 0.015
sterol homeostasis GO:0055092 4 0.015
regulation of developmental growth GO:0048638 174 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
positive regulation of endopeptidase activity GO:0010950 26 0.015
regulation of synapse structure and activity GO:0050803 128 0.015
negative regulation of cell cycle process GO:0010948 109 0.015
epithelial tube morphogenesis GO:0060562 88 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.015
stem cell proliferation GO:0072089 88 0.015
regulation of apoptotic process GO:0042981 130 0.015
spindle organization GO:0007051 253 0.015
body morphogenesis GO:0010171 2 0.015
compound eye development GO:0048749 307 0.015
epidermal growth factor receptor signaling pathway GO:0007173 58 0.015
imaginal disc derived leg morphogenesis GO:0007480 80 0.015
embryonic pattern specification GO:0009880 174 0.015
single organism catabolic process GO:0044712 228 0.015
lateral inhibition GO:0046331 206 0.015
response to lipopolysaccharide GO:0032496 4 0.015
modification dependent protein catabolic process GO:0019941 78 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
mapk cascade GO:0000165 107 0.014
endodermal cell fate commitment GO:0001711 3 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
multi organism behavior GO:0051705 175 0.014
outflow tract morphogenesis GO:0003151 4 0.014
protein phosphorylation GO:0006468 169 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
regulation of response to stress GO:0080134 200 0.014
mitotic cell cycle phase transition GO:0044772 138 0.014
leg disc development GO:0035218 92 0.014
compound eye morphogenesis GO:0001745 249 0.014
regulation of defense response GO:0031347 102 0.014
purine containing compound metabolic process GO:0072521 155 0.014
nephrocyte filtration GO:0097206 7 0.014
eye photoreceptor cell differentiation GO:0001754 145 0.014
extrinsic apoptotic signaling pathway GO:0097191 1 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
stem cell development GO:0048864 79 0.014
multi organism reproductive behavior GO:0044705 121 0.014
nucleotide metabolic process GO:0009117 161 0.014
renal tubule morphogenesis GO:0061333 44 0.014
regulation of cell development GO:0060284 215 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
notch signaling pathway GO:0007219 120 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
salivary gland morphogenesis GO:0007435 145 0.014
skeletal muscle fiber development GO:0048741 3 0.014
guanosine containing compound metabolic process GO:1901068 74 0.013
ras protein signal transduction GO:0007265 88 0.013
nucleoside catabolic process GO:0009164 112 0.013
salivary gland cell autophagic cell death GO:0035071 83 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
localization of cell GO:0051674 257 0.013
stem cell differentiation GO:0048863 117 0.013
mrna metabolic process GO:0016071 124 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
regulation of proteolysis GO:0030162 87 0.013
single organism biosynthetic process GO:0044711 206 0.013
anatomical structure homeostasis GO:0060249 97 0.013
embryonic morphogenesis GO:0048598 206 0.013
response to nutrient levels GO:0031667 114 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
regulation of establishment of protein localization GO:0070201 61 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
anterior posterior axis specification GO:0009948 109 0.013
digestive system development GO:0055123 149 0.013
microtubule based movement GO:0007018 51 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
autophagic cell death GO:0048102 83 0.013
positive regulation of nervous system development GO:0051962 69 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
ion transport GO:0006811 145 0.013
positive regulation of biosynthetic process GO:0009891 316 0.013
gene silencing GO:0016458 138 0.012
head development GO:0060322 135 0.012
negative regulation of signal transduction GO:0009968 206 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.012
intracellular protein transport GO:0006886 104 0.012
vesicle mediated transport GO:0016192 381 0.012
apoptotic process GO:0006915 159 0.012
positive regulation of nucleotide catabolic process GO:0030813 46 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
organophosphate catabolic process GO:0046434 112 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
cellular amine metabolic process GO:0044106 12 0.012
regulation of mapk cascade GO:0043408 92 0.012
negative regulation of cell cycle GO:0045786 116 0.012
nucleocytoplasmic transport GO:0006913 72 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
stem cell division GO:0017145 69 0.012
oxoacid metabolic process GO:0043436 103 0.012
hormone catabolic process GO:0042447 3 0.012
embryonic hindgut morphogenesis GO:0048619 48 0.012
urogenital system development GO:0001655 72 0.012
regulation of transport GO:0051049 181 0.012
mitotic nuclear division GO:0007067 213 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
synapse organization GO:0050808 196 0.012
dendrite development GO:0016358 204 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
organic acid metabolic process GO:0006082 103 0.012
cell motility GO:0048870 251 0.012
nuclear division GO:0000280 332 0.012
immune system process GO:0002376 347 0.012
histone modification GO:0016570 106 0.012
regulation of protein localization GO:0032880 76 0.012
protein modification by small protein conjugation GO:0032446 79 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
regulation of mrna processing GO:0050684 71 0.011
regulation of nervous system development GO:0051960 248 0.011
nephron epithelium development GO:0072009 3 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
kidney epithelium development GO:0072073 3 0.011
nucleus organization GO:0006997 45 0.011
centrosome organization GO:0051297 163 0.011
regulation of programmed cell death GO:0043067 152 0.011
negative regulation of signaling GO:0023057 219 0.011
dendrite morphogenesis GO:0048813 199 0.011
mesoderm development GO:0007498 78 0.011
chemosensory behavior GO:0007635 106 0.011
gland development GO:0048732 191 0.011
myotube cell development GO:0014904 3 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
cellular macromolecule localization GO:0070727 220 0.011
retina development in camera type eye GO:0060041 4 0.011
axon development GO:0061564 297 0.011
signal transduction in response to dna damage GO:0042770 3 0.011
microtubule organizing center organization GO:0031023 168 0.011
blastoderm segmentation GO:0007350 159 0.011
anterior posterior pattern specification GO:0009952 136 0.011
monocarboxylic acid transport GO:0015718 3 0.011
response to sterol GO:0036314 34 0.011
microtubule based transport GO:0010970 42 0.011
covalent chromatin modification GO:0016569 106 0.011
regulation of cellular localization GO:0060341 136 0.011
sex differentiation GO:0007548 81 0.011
response to ketone GO:1901654 34 0.011
kidney development GO:0001822 3 0.010
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.010
regulation of epithelial cell differentiation GO:0030856 4 0.010
positive regulation of cell development GO:0010720 61 0.010
glycosyl compound catabolic process GO:1901658 112 0.010
response to wounding GO:0009611 94 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
homeostatic process GO:0042592 199 0.010
regulation of neurogenesis GO:0050767 158 0.010
multi multicellular organism process GO:0044706 123 0.010
muscle cell development GO:0055001 50 0.010
circulatory system development GO:0072359 82 0.010
limb morphogenesis GO:0035108 1 0.010
regulation of immune system process GO:0002682 176 0.010
regulation of growth GO:0040008 233 0.010
regulation of cellular response to stress GO:0080135 89 0.010

CHES-1-like disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.015
musculoskeletal system disease DOID:17 0 0.011
sensory system disease DOID:0050155 0 0.010
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010
eye and adnexa disease DOID:1492 0 0.010