Drosophila melanogaster

66 known processes

Mtp (Dmel_CG9342)

Microsomal triacylglycerol transfer protein

(Aliases: Dmel\CG9342,CG9342,CT3751,MTP,dMTP)

Mtp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid metabolic process GO:0006629 121 0.589
regulation of lipid storage GO:0010883 22 0.446
dendrite development GO:0016358 204 0.363
maintenance of location GO:0051235 73 0.354
open tracheal system development GO:0007424 204 0.254
cellular lipid metabolic process GO:0044255 83 0.233
regulation of cell differentiation GO:0045595 302 0.220
epithelial tube morphogenesis GO:0060562 88 0.204
branching involved in open tracheal system development GO:0060446 45 0.203
branching morphogenesis of an epithelial tube GO:0048754 45 0.184
trachea morphogenesis GO:0060439 22 0.184
regulation of localization GO:0032879 275 0.181
appendage development GO:0048736 401 0.172
vesicle mediated transport GO:0016192 381 0.154
response to alcohol GO:0097305 95 0.151
lipid biosynthetic process GO:0008610 46 0.145
respiratory system development GO:0060541 213 0.135
lipid storage GO:0019915 38 0.131
cellular response to endogenous stimulus GO:0071495 80 0.120
triglyceride metabolic process GO:0006641 12 0.111
regulation of dendrite development GO:0050773 37 0.110
dendrite morphogenesis GO:0048813 199 0.108
morphogenesis of a branching epithelium GO:0061138 45 0.107
organic substance catabolic process GO:1901575 308 0.106
morphogenesis of an epithelium GO:0002009 276 0.103
imaginal disc derived appendage morphogenesis GO:0035114 395 0.102
endocytosis GO:0006897 310 0.099
tube development GO:0035295 244 0.095
tissue morphogenesis GO:0048729 297 0.091
lipid localization GO:0010876 54 0.091
cell motility GO:0048870 251 0.087
regulation of cell development GO:0060284 215 0.086
positive regulation of cellular biosynthetic process GO:0031328 316 0.085
small molecule metabolic process GO:0044281 305 0.084
imaginal disc derived wing morphogenesis GO:0007476 337 0.082
trachea development GO:0060438 29 0.079
terminal branching open tracheal system GO:0007430 17 0.078
single organism biosynthetic process GO:0044711 206 0.077
response to oxygen containing compound GO:1901700 200 0.077
organonitrogen compound biosynthetic process GO:1901566 117 0.074
aging GO:0007568 143 0.072
positive regulation of lipid storage GO:0010884 4 0.068
regulation of catabolic process GO:0009894 170 0.068
developmental programmed cell death GO:0010623 138 0.062
response to lipopolysaccharide GO:0032496 4 0.062
morphogenesis of a branching structure GO:0001763 45 0.061
carboxylic acid metabolic process GO:0019752 92 0.060
multicellular organismal aging GO:0010259 140 0.060
positive regulation of signaling GO:0023056 243 0.058
border follicle cell migration GO:0007298 113 0.056
fatty acid oxidation GO:0019395 6 0.053
phosphatidylinositol mediated signaling GO:0048015 4 0.053
fatty acid beta oxidation GO:0006635 6 0.052
very long chain fatty acid metabolic process GO:0000038 4 0.052
determination of adult lifespan GO:0008340 137 0.049
lipid modification GO:0030258 24 0.046
regulation of neuron projection development GO:0010975 69 0.045
cellular response to nitrogen compound GO:1901699 51 0.045
acylglycerol metabolic process GO:0006639 12 0.044
negative regulation of developmental process GO:0051093 201 0.044
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.044
regulation of nurse cell apoptotic process GO:0045477 9 0.043
monocarboxylic acid metabolic process GO:0032787 29 0.043
immune system process GO:0002376 347 0.042
positive regulation of rna biosynthetic process GO:1902680 266 0.042
imaginal disc derived appendage development GO:0048737 399 0.041
wing disc morphogenesis GO:0007472 344 0.041
appendage morphogenesis GO:0035107 397 0.041
response to bacterium GO:0009617 198 0.040
regulation of protein complex disassembly GO:0043244 29 0.040
response to growth factor GO:0070848 31 0.039
regulation of nervous system development GO:0051960 248 0.039
transcription from rna polymerase ii promoter GO:0006366 368 0.039
positive regulation of molecular function GO:0044093 136 0.039
tube morphogenesis GO:0035239 191 0.038
regulation of multi organism process GO:0043900 131 0.038
regulation of multicellular organismal development GO:2000026 414 0.038
response to ethanol GO:0045471 59 0.038
positive regulation of catabolic process GO:0009896 105 0.037
regulation of molecular function GO:0065009 217 0.036
establishment of localization in cell GO:0051649 402 0.035
glial cell development GO:0021782 27 0.035
central nervous system development GO:0007417 201 0.035
regulation of neuron differentiation GO:0045664 103 0.034
organic acid metabolic process GO:0006082 103 0.034
epithelial cell differentiation GO:0030855 322 0.034
cell maturation GO:0048469 144 0.034
catabolic process GO:0009056 409 0.033
stem cell development GO:0048864 79 0.033
response to abiotic stimulus GO:0009628 341 0.033
kidney development GO:0001822 3 0.033
head development GO:0060322 135 0.032
response to external biotic stimulus GO:0043207 293 0.031
glycerolipid metabolic process GO:0046486 34 0.031
cell migration GO:0016477 238 0.030
nucleotide metabolic process GO:0009117 161 0.030
oxoacid metabolic process GO:0043436 103 0.030
organophosphate metabolic process GO:0019637 195 0.029
cholesterol transport GO:0030301 2 0.029
metal ion homeostasis GO:0055065 44 0.029
phagocytosis GO:0006909 215 0.029
carbohydrate derivative metabolic process GO:1901135 217 0.028
response to other organism GO:0051707 293 0.028
response to biotic stimulus GO:0009607 294 0.028
homeostatic process GO:0042592 199 0.027
cognition GO:0050890 141 0.027
septate junction assembly GO:0019991 26 0.026
regulation of lipid metabolic process GO:0019216 15 0.026
forebrain development GO:0030900 2 0.026
organic substance transport GO:0071702 257 0.026
intracellular transport GO:0046907 228 0.025
spermatogenesis GO:0007283 200 0.025
organic hydroxy compound metabolic process GO:1901615 83 0.025
regulation of cellular localization GO:0060341 136 0.024
single organism intracellular transport GO:1902582 207 0.024
interspecies interaction between organisms GO:0044419 16 0.024
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.024
post embryonic appendage morphogenesis GO:0035120 385 0.024
sterol homeostasis GO:0055092 4 0.024
regulation of anatomical structure morphogenesis GO:0022603 242 0.024
embryonic morphogenesis GO:0048598 206 0.024
regulation of establishment of protein localization GO:0070201 61 0.023
acylglycerol catabolic process GO:0046464 3 0.023
regulation of neurogenesis GO:0050767 158 0.023
neutral lipid metabolic process GO:0006638 12 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.023
response to extracellular stimulus GO:0009991 116 0.023
positive regulation of gene expression GO:0010628 290 0.022
purine nucleotide metabolic process GO:0006163 146 0.021
single organism catabolic process GO:0044712 228 0.021
nucleobase containing small molecule metabolic process GO:0055086 174 0.021
establishment of protein localization GO:0045184 163 0.021
protein localization GO:0008104 284 0.021
regulation of protein transport GO:0051223 57 0.021
carbohydrate metabolic process GO:0005975 82 0.021
response to starvation GO:0042594 97 0.021
body morphogenesis GO:0010171 2 0.020
regulation of dendrite morphogenesis GO:0048814 28 0.020
steroid metabolic process GO:0008202 20 0.020
cellular ketone metabolic process GO:0042180 24 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.020
lipid catabolic process GO:0016042 21 0.020
regulation of intracellular protein transport GO:0033157 46 0.020
extracellular matrix disassembly GO:0022617 4 0.020
chemosensory behavior GO:0007635 106 0.019
syncytium formation GO:0006949 43 0.019
organonitrogen compound metabolic process GO:1901564 318 0.019
cellular protein localization GO:0034613 160 0.019
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.018
negative regulation of cellular component organization GO:0051129 108 0.018
skin development GO:0043588 65 0.018
striated muscle cell differentiation GO:0051146 90 0.018
positive regulation of rna metabolic process GO:0051254 271 0.018
hemopoiesis GO:0030097 46 0.018
cellular response to nutrient levels GO:0031669 62 0.018
regulation of vesicle mediated transport GO:0060627 59 0.018
cellular response to light stimulus GO:0071482 37 0.017
defense response GO:0006952 300 0.017
protein transport GO:0015031 155 0.017
mesenchymal cell differentiation GO:0048762 1 0.017
regulation of catalytic activity GO:0050790 185 0.017
regulation of cell proliferation GO:0042127 163 0.017
negative regulation of signal transduction GO:0009968 206 0.017
ovarian follicle cell development GO:0030707 248 0.017
inositol lipid mediated signaling GO:0048017 4 0.017
negative regulation of cell communication GO:0010648 223 0.017
autophagic vacuole assembly GO:0000045 2 0.016
pigmentation GO:0043473 75 0.016
negative regulation of rna metabolic process GO:0051253 251 0.016
ion homeostasis GO:0050801 55 0.016
response to nutrient levels GO:0031667 114 0.016
acetate ester biosynthetic process GO:1900620 1 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
single organism carbohydrate metabolic process GO:0044723 72 0.016
cellular catabolic process GO:0044248 372 0.016
cellular response to lipopolysaccharide GO:0071222 3 0.016
feeding behavior GO:0007631 50 0.015
regulation of cell morphogenesis GO:0022604 163 0.015
positive regulation of response to stimulus GO:0048584 323 0.015
regionalization GO:0003002 416 0.015
negative regulation of cell development GO:0010721 62 0.015
wound healing GO:0042060 75 0.015
single organism behavior GO:0044708 391 0.015
cellular response to peptide GO:1901653 28 0.015
chemical homeostasis GO:0048878 92 0.015
organelle fission GO:0048285 340 0.015
positive regulation of nucleic acid templated transcription GO:1903508 266 0.015
protein import into nucleus GO:0006606 51 0.014
ovarian follicle cell migration GO:0007297 121 0.014
regulation of programmed cell death GO:0043067 152 0.014
negative regulation of rna biosynthetic process GO:1902679 240 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
eye pigment biosynthetic process GO:0006726 32 0.013
intracellular protein transport GO:0006886 104 0.013
mesenchymal cell development GO:0014031 1 0.013
purine nucleoside metabolic process GO:0042278 127 0.013
positive regulation of biosynthetic process GO:0009891 316 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.013
regulation of cellular component size GO:0032535 98 0.013
response to organic substance GO:0010033 284 0.013
retina development in camera type eye GO:0060041 4 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.013
metal ion transport GO:0030001 74 0.013
neurotransmitter metabolic process GO:0042133 2 0.012
regulation of nucleocytoplasmic transport GO:0046822 35 0.012
fatty acid homeostasis GO:0055089 2 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
antibacterial humoral response GO:0019731 44 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
triglyceride catabolic process GO:0019433 3 0.012
substrate adhesion dependent cell spreading GO:0034446 2 0.012
regulation of bmp signaling pathway GO:0030510 23 0.012
steroid biosynthetic process GO:0006694 16 0.012
detection of external biotic stimulus GO:0098581 2 0.012
cellular response to organonitrogen compound GO:0071417 36 0.012
nuclear transport GO:0051169 72 0.012
fatty acid catabolic process GO:0009062 9 0.011
telencephalon development GO:0021537 2 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
cell death GO:0008219 279 0.011
cellular macromolecule localization GO:0070727 220 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
rho protein signal transduction GO:0007266 14 0.011
epithelial cell migration GO:0010631 148 0.011
cellular response to starvation GO:0009267 61 0.011
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.011
retrograde axon cargo transport GO:0008090 9 0.011
humoral immune response GO:0006959 117 0.011
brain development GO:0007420 120 0.011
detection of visible light GO:0009584 38 0.011
negative regulation of cellular metabolic process GO:0031324 382 0.011
exocrine system development GO:0035272 162 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
monocarboxylic acid transport GO:0015718 3 0.010
cholesterol homeostasis GO:0042632 3 0.010
organelle assembly GO:0070925 198 0.010
protein localization to organelle GO:0033365 82 0.010
programmed cell death GO:0012501 257 0.010
glial cell differentiation GO:0010001 35 0.010
regulation of cellular protein metabolic process GO:0032268 243 0.010
zinc ion homeostasis GO:0055069 6 0.010

Mtp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.041
musculoskeletal system disease DOID:17 0 0.041
connective tissue disease DOID:65 0 0.041
bone disease DOID:0080001 0 0.017
nervous system disease DOID:863 0 0.011
disease of metabolism DOID:0014667 0 0.011
carbohydrate metabolism disease DOID:0050013 0 0.011
glucose metabolism disease DOID:4194 0 0.011
acquired metabolic disease DOID:0060158 0 0.011