Drosophila melanogaster

0 known processes

hgo (Dmel_CG4779)

homogentisate 1,2-dioxygenase

(Aliases: Dmel\CG4779,CG4779)

hgo biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
catabolic process GO:0009056 409 0.100
small molecule metabolic process GO:0044281 305 0.089
cellular catabolic process GO:0044248 372 0.071
alpha amino acid metabolic process GO:1901605 20 0.061
steroid catabolic process GO:0006706 1 0.061
organic substance catabolic process GO:1901575 308 0.056
carboxylic acid metabolic process GO:0019752 92 0.056
neurological system process GO:0050877 358 0.047
organic acid metabolic process GO:0006082 103 0.046
organic substance transport GO:0071702 257 0.045
sensory perception of chemical stimulus GO:0007606 116 0.044
cellular amino acid metabolic process GO:0006520 61 0.044
organonitrogen compound catabolic process GO:1901565 128 0.043
establishment of localization in cell GO:0051649 402 0.041
organonitrogen compound biosynthetic process GO:1901566 117 0.040
organonitrogen compound metabolic process GO:1901564 318 0.040
response to starvation GO:0042594 97 0.039
positive regulation of signaling GO:0023056 243 0.037
endocytosis GO:0006897 310 0.037
mating GO:0007618 120 0.037
oxoacid metabolic process GO:0043436 103 0.036
multi organism behavior GO:0051705 175 0.036
response to other organism GO:0051707 293 0.035
response to abiotic stimulus GO:0009628 341 0.035
heterocycle catabolic process GO:0046700 166 0.035
appendage development GO:0048736 401 0.035
imaginal disc derived appendage development GO:0048737 399 0.035
response to nutrient levels GO:0031667 114 0.035
intracellular transport GO:0046907 228 0.034
positive regulation of response to stimulus GO:0048584 323 0.034
male mating behavior GO:0060179 70 0.034
post embryonic appendage morphogenesis GO:0035120 385 0.034
response to organic substance GO:0010033 284 0.034
vesicle mediated transport GO:0016192 381 0.033
response to bacterium GO:0009617 198 0.033
response to extracellular stimulus GO:0009991 116 0.033
sensory perception of smell GO:0007608 80 0.032
response to lipopolysaccharide GO:0032496 4 0.032
protein modification process GO:0036211 438 0.032
organelle fission GO:0048285 340 0.032
axis specification GO:0009798 167 0.032
organic cyclic compound catabolic process GO:1901361 168 0.031
wing disc morphogenesis GO:0007472 344 0.031
phagocytosis GO:0006909 215 0.031
intracellular signal transduction GO:0035556 300 0.030
aromatic compound catabolic process GO:0019439 166 0.030
developmental growth GO:0048589 280 0.030
rhythmic process GO:0048511 106 0.029
imaginal disc derived appendage morphogenesis GO:0035114 395 0.029
inter male aggressive behavior GO:0002121 60 0.028
cellular protein modification process GO:0006464 438 0.028
nuclear division GO:0000280 332 0.027
courtship behavior GO:0007619 68 0.027
positive regulation of cell communication GO:0010647 250 0.027
anion homeostasis GO:0055081 3 0.026
sensory perception GO:0007600 196 0.026
single organism biosynthetic process GO:0044711 206 0.025
vitamin biosynthetic process GO:0009110 1 0.025
response to oxygen containing compound GO:1901700 200 0.025
single organism catabolic process GO:0044712 228 0.025
regionalization GO:0003002 416 0.025
imaginal disc derived wing morphogenesis GO:0007476 337 0.025
positive regulation of signal transduction GO:0009967 223 0.025
compound eye development GO:0048749 307 0.025
response to external biotic stimulus GO:0043207 293 0.024
body morphogenesis GO:0010171 2 0.024
macromolecular complex assembly GO:0065003 256 0.024
cellular ketone metabolic process GO:0042180 24 0.024
single organism behavior GO:0044708 391 0.024
epithelial cell development GO:0002064 274 0.024
medium chain fatty acid metabolic process GO:0051791 1 0.024
carbohydrate derivative metabolic process GO:1901135 217 0.023
dorsal ventral pattern formation GO:0009953 133 0.023
response to mercury ion GO:0046689 3 0.023
xenobiotic catabolic process GO:0042178 1 0.023
regulation of localization GO:0032879 275 0.023
benzene containing compound metabolic process GO:0042537 3 0.023
single organism intracellular transport GO:1902582 207 0.022
response to organic cyclic compound GO:0014070 89 0.022
adult behavior GO:0030534 137 0.022
regulation of cell cycle GO:0051726 291 0.022
estrogen metabolic process GO:0008210 1 0.022
insecticide metabolic process GO:0017143 2 0.022
cell proliferation GO:0008283 299 0.021
phosphorylation GO:0016310 294 0.021
appendage morphogenesis GO:0035107 397 0.021
kidney development GO:0001822 3 0.021
dorsal ventral axis specification GO:0009950 66 0.021
growth GO:0040007 359 0.021
negative regulation of cellular metabolic process GO:0031324 382 0.021
protein complex biogenesis GO:0070271 201 0.020
cell motility GO:0048870 251 0.020
response to biotic stimulus GO:0009607 294 0.020
hormone catabolic process GO:0042447 3 0.020
jak stat cascade GO:0007259 49 0.020
response to fungus GO:0009620 50 0.020
protein complex assembly GO:0006461 200 0.020
defense response GO:0006952 300 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
response to endogenous stimulus GO:0009719 119 0.019
negative regulation of gene expression GO:0010629 387 0.019
response to alcohol GO:0097305 95 0.019
response to glucose GO:0009749 2 0.019
localization of cell GO:0051674 257 0.019
regulation of intracellular signal transduction GO:1902531 236 0.019
monocarboxylic acid transport GO:0015718 3 0.018
oxidation reduction process GO:0055114 123 0.018
reproductive behavior GO:0019098 122 0.018
death GO:0016265 284 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.017
positive regulation of gene expression GO:0010628 290 0.017
defense response to other organism GO:0098542 225 0.017
cell death GO:0008219 279 0.017
programmed cell death GO:0012501 257 0.017
eye development GO:0001654 323 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
cellular response to ethanol GO:0071361 4 0.017
epithelial cell differentiation GO:0030855 322 0.017
border follicle cell migration GO:0007298 113 0.017
regulation of transport GO:0051049 181 0.017
positive regulation of macromolecule metabolic process GO:0010604 405 0.017
response to monosaccharide GO:0034284 4 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
protein maturation GO:0051604 71 0.016
sensory organ morphogenesis GO:0090596 260 0.016
homeostatic process GO:0042592 199 0.016
sterol homeostasis GO:0055092 4 0.016
multi organism reproductive behavior GO:0044705 121 0.016
response to oxidative stress GO:0006979 86 0.016
tyrosine metabolic process GO:0006570 1 0.016
oligosaccharide transport GO:0015772 2 0.016
regulation of multicellular organismal development GO:2000026 414 0.016
positive regulation of biosynthetic process GO:0009891 316 0.016
response to organophosphorus GO:0046683 2 0.016
carbohydrate derivative catabolic process GO:1901136 118 0.016
chaeta development GO:0022416 97 0.016
carboxylic acid transport GO:0046942 18 0.016
indole containing compound biosynthetic process GO:0042435 4 0.015
ion transport GO:0006811 145 0.015
taxis GO:0042330 304 0.015
organic hydroxy compound biosynthetic process GO:1901617 21 0.015
organophosphate metabolic process GO:0019637 195 0.015
amine metabolic process GO:0009308 12 0.015
camera type eye development GO:0043010 4 0.015
macromolecule catabolic process GO:0009057 161 0.015
response to hexose GO:0009746 3 0.015
regulation of protein metabolic process GO:0051246 256 0.015
regulation of cellular localization GO:0060341 136 0.015
regulation of developmental growth GO:0048638 174 0.015
aggressive behavior GO:0002118 63 0.015
single organism carbohydrate metabolic process GO:0044723 72 0.015
gland development GO:0048732 191 0.015
organic hydroxy compound metabolic process GO:1901615 83 0.015
cation transport GO:0006812 110 0.015
multicellular organismal reproductive behavior GO:0033057 110 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.015
regulation of cell death GO:0010941 173 0.015
nucleobase containing compound catabolic process GO:0034655 165 0.015
small molecule catabolic process GO:0044282 21 0.014
phenol containing compound metabolic process GO:0018958 57 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
regulation of growth GO:0040008 233 0.014
meiotic nuclear division GO:0007126 151 0.014
cellular amine metabolic process GO:0044106 12 0.014
mitotic nuclear division GO:0007067 213 0.014
l amino acid import GO:0043092 2 0.014
purine containing compound catabolic process GO:0072523 112 0.014
meiosis i GO:0007127 59 0.014
positive regulation of cell migration GO:0030335 2 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
meiotic cell cycle process GO:1903046 132 0.014
immune response activating signal transduction GO:0002757 2 0.014
open tracheal system development GO:0007424 204 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
proteolysis GO:0006508 192 0.013
male courtship behavior GO:0008049 63 0.013
fat soluble vitamin metabolic process GO:0006775 1 0.013
regulation of immune response GO:0050776 118 0.013
negative regulation of cell communication GO:0010648 223 0.013
aromatic amino acid family metabolic process GO:0009072 3 0.013
male gamete generation GO:0048232 201 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
neutral lipid biosynthetic process GO:0046460 2 0.013
protein processing GO:0016485 68 0.013
regulation of molecular function GO:0065009 217 0.013
tissue morphogenesis GO:0048729 297 0.013
immune response regulating signaling pathway GO:0002764 2 0.013
regulation of anatomical structure size GO:0090066 163 0.013
cell migration GO:0016477 238 0.013
autophagy GO:0006914 108 0.013
axon guidance GO:0007411 233 0.013
feeding behavior GO:0007631 50 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
negative regulation of signal transduction GO:0009968 206 0.013
purine nucleoside metabolic process GO:0042278 127 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
chromosome organization GO:0051276 360 0.013
meiotic cell cycle GO:0051321 171 0.012
purine containing compound metabolic process GO:0072521 155 0.012
respiratory system development GO:0060541 213 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
polyol biosynthetic process GO:0046173 3 0.012
neutral lipid catabolic process GO:0046461 3 0.012
multi multicellular organism process GO:0044706 123 0.012
regulation of response to stress GO:0080134 200 0.012
endomembrane system organization GO:0010256 119 0.012
sulfur compound metabolic process GO:0006790 59 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
regulation of lipid transport GO:0032368 3 0.012
response to temperature stimulus GO:0009266 106 0.012
carbohydrate metabolic process GO:0005975 82 0.012
immune system process GO:0002376 347 0.012
chromosome segregation GO:0007059 157 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
cellular response to organic substance GO:0071310 132 0.012
regulation of immune system process GO:0002682 176 0.012
ethanolamine containing compound metabolic process GO:0042439 4 0.012
response to radiation GO:0009314 155 0.012
regulation of programmed cell death GO:0043067 152 0.012
telencephalon development GO:0021537 2 0.012
actin filament based process GO:0030029 220 0.012
mesoderm development GO:0007498 78 0.012
pattern recognition receptor signaling pathway GO:0002221 2 0.012
chemotaxis GO:0006935 249 0.011
neuron projection guidance GO:0097485 241 0.011
regulation of catalytic activity GO:0050790 185 0.011
spermatid differentiation GO:0048515 114 0.011
cell cycle phase transition GO:0044770 140 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
detection of stimulus GO:0051606 156 0.011
nucleoside catabolic process GO:0009164 112 0.011
connective tissue development GO:0061448 3 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
negative regulation of signaling GO:0023057 219 0.011
regulation of organelle organization GO:0033043 196 0.011
segmentation GO:0035282 207 0.011
spindle organization GO:0007051 253 0.011
forebrain development GO:0030900 2 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
regulation of cell proliferation GO:0042127 163 0.011
organophosphate catabolic process GO:0046434 112 0.011
carbohydrate derivative biosynthetic process GO:1901137 85 0.011
circadian rhythm GO:0007623 105 0.011
regulation of catabolic process GO:0009894 170 0.011
acetylcholine catabolic process GO:0006581 1 0.011
protein phosphorylation GO:0006468 169 0.011
positive regulation of transport GO:0051050 92 0.011
apoptotic process GO:0006915 159 0.011
nitrogen compound transport GO:0071705 85 0.011
glycosyl compound catabolic process GO:1901658 112 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
cellular modified amino acid metabolic process GO:0006575 45 0.011
cuticle development GO:0042335 86 0.011
alditol phosphate metabolic process GO:0052646 2 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
disaccharide transport GO:0015766 2 0.011
multicellular organismal aging GO:0010259 140 0.011
phospholipid homeostasis GO:0055091 1 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.010
cellularization GO:0007349 90 0.010
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.010
nucleoside metabolic process GO:0009116 127 0.010
enzyme linked receptor protein signaling pathway GO:0007167 179 0.010
aging GO:0007568 143 0.010
notch signaling pathway GO:0007219 120 0.010
cellular response to endogenous stimulus GO:0071495 80 0.010
response to nitrogen compound GO:1901698 90 0.010
female meiotic division GO:0007143 70 0.010
regulation of cellular amino acid metabolic process GO:0006521 0 0.010
signal transduction by phosphorylation GO:0023014 107 0.010
compound eye morphogenesis GO:0001745 249 0.010
rna processing GO:0006396 147 0.010
response to organonitrogen compound GO:0010243 75 0.010
response to hormone GO:0009725 45 0.010
drinking behavior GO:0042756 2 0.010
nucleoside phosphate metabolic process GO:0006753 162 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
actin cytoskeleton organization GO:0030036 206 0.010

hgo disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.056
disease of metabolism DOID:0014667 0 0.037
inherited metabolic disorder DOID:655 0 0.028
nervous system disease DOID:863 0 0.026
cardiovascular system disease DOID:1287 0 0.023
acquired metabolic disease DOID:0060158 0 0.019
carbohydrate metabolism disease DOID:0050013 0 0.019
diabetes mellitus DOID:9351 0 0.019
glucose metabolism disease DOID:4194 0 0.019
type 2 diabetes mellitus DOID:9352 0 0.016
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.015
central nervous system disease DOID:331 0 0.015
musculoskeletal system disease DOID:17 0 0.015
vascular disease DOID:178 0 0.013
artery disease DOID:0050828 0 0.012
hypertension DOID:10763 0 0.012
essential hypertension DOID:10825 0 0.012
lipid metabolism disorder DOID:3146 0 0.010
familial lipoprotein lipase deficiency DOID:14118 0 0.010
familial hyperlipidemia DOID:1168 0 0.010