Drosophila melanogaster

100 known processes

Sfmbt (Dmel_CG16975)

Scm-related gene containing four mbt domains

(Aliases: dSFMBT,dSfmbt,Dmel\CG16975,CG16975,SFMBT)

Sfmbt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of response to stimulus GO:0048585 258 0.602
stem cell development GO:0048864 79 0.597
negative regulation of signaling GO:0023057 219 0.595
cellular response to chemical stimulus GO:0070887 199 0.578
stem cell differentiation GO:0048863 117 0.569
cellular response to organic substance GO:0071310 132 0.509
negative regulation of signal transduction GO:0009968 206 0.456
negative regulation of cell communication GO:0010648 223 0.452
transcription from rna polymerase ii promoter GO:0006366 368 0.428
Fly
dna damage checkpoint GO:0000077 78 0.328
mitotic dna integrity checkpoint GO:0044774 75 0.300
negative regulation of developmental process GO:0051093 201 0.291
Worm
rna processing GO:0006396 147 0.289
enzyme linked receptor protein signaling pathway GO:0007167 179 0.282
mrna metabolic process GO:0016071 124 0.278
spindle organization GO:0007051 253 0.269
regulation of response to stress GO:0080134 200 0.256
cell cycle phase transition GO:0044770 140 0.232
negative regulation of cell cycle phase transition GO:1901988 103 0.209
regulation of cell differentiation GO:0045595 302 0.202
determination of adult lifespan GO:0008340 137 0.197
response to oxygen containing compound GO:1901700 200 0.193
regulation of immune system process GO:0002682 176 0.188
proteolysis GO:0006508 192 0.165
response to organic substance GO:0010033 284 0.154
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.143
positive regulation of transcription dna templated GO:0045893 266 0.142
dna templated transcription elongation GO:0006354 18 0.141
cell division GO:0051301 248 0.140
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.131
regulation of immune response GO:0050776 118 0.128
immune response GO:0006955 246 0.127
regulation of mitotic cell cycle GO:0007346 190 0.124
Fly
immune system process GO:0002376 347 0.122
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.119
negative regulation of cellular metabolic process GO:0031324 382 0.106
positive regulation of neuron projection regeneration GO:0070572 3 0.105
positive regulation of cellular biosynthetic process GO:0031328 316 0.105
defense response GO:0006952 300 0.102
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.102
Fly
response to external biotic stimulus GO:0043207 293 0.101
regulation of cell development GO:0060284 215 0.096
response to other organism GO:0051707 293 0.091
multicellular organismal aging GO:0010259 140 0.089
positive regulation of response to stimulus GO:0048584 323 0.085
response to endogenous stimulus GO:0009719 119 0.084
regulation of chromosome organization GO:0033044 64 0.084
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.081
cell proliferation GO:0008283 299 0.077
Fly
organelle fission GO:0048285 340 0.074
cellular response to endogenous stimulus GO:0071495 80 0.073
catabolic process GO:0009056 409 0.073
negative regulation of cell differentiation GO:0045596 143 0.070
macromolecular complex assembly GO:0065003 256 0.069
regulation of cell cycle phase transition GO:1901987 130 0.068
positive regulation of developmental process GO:0051094 143 0.067
response to oxidative stress GO:0006979 86 0.067
mitotic cell cycle phase transition GO:0044772 138 0.066
regulation of response to external stimulus GO:0032101 115 0.063
regulation of mitotic cell cycle phase transition GO:1901990 130 0.062
defense response to other organism GO:0098542 225 0.062
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.062
embryo development ending in birth or egg hatching GO:0009792 152 0.061
Mouse Fly
establishment of localization in cell GO:0051649 402 0.060
Fly
eye development GO:0001654 323 0.059
negative regulation of cell cycle process GO:0010948 109 0.058
response to biotic stimulus GO:0009607 294 0.058
positive regulation of biosynthetic process GO:0009891 316 0.057
regulation of cell proliferation GO:0042127 163 0.057
Fly
protein transport GO:0015031 155 0.057
mitotic nuclear division GO:0007067 213 0.057
cell cycle checkpoint GO:0000075 95 0.054
positive regulation of growth GO:0045927 75 0.051
cellular catabolic process GO:0044248 372 0.051
regulation of defense response GO:0031347 102 0.051
cellular response to oxygen containing compound GO:1901701 79 0.050
negative regulation of gene expression GO:0010629 387 0.049
regulation of immune effector process GO:0002697 52 0.048
sensory organ morphogenesis GO:0090596 260 0.048
macromolecule catabolic process GO:0009057 161 0.046
positive regulation of rna metabolic process GO:0051254 271 0.045
response to alcohol GO:0097305 95 0.045
locomotory behavior GO:0007626 176 0.044
peptidyl lysine modification GO:0018205 57 0.043
cell death GO:0008219 279 0.043
mitotic g2 dna damage checkpoint GO:0007095 69 0.043
cellular macromolecule catabolic process GO:0044265 136 0.042
positive regulation of cellular component organization GO:0051130 156 0.042
regulation of cell cycle process GO:0010564 181 0.041
intracellular steroid hormone receptor signaling pathway GO:0030518 12 0.041
compound eye development GO:0048749 307 0.041
protein complex assembly GO:0006461 200 0.040
sister chromatid segregation GO:0000819 92 0.040
g1 s transition of mitotic cell cycle GO:0000082 31 0.039
chemotaxis GO:0006935 249 0.039
endocytosis GO:0006897 310 0.039
mitotic cell cycle checkpoint GO:0007093 88 0.039
positive regulation of developmental growth GO:0048639 62 0.038
organic substance transport GO:0071702 257 0.038
stem cell division GO:0017145 69 0.037
nuclear division GO:0000280 332 0.037
mitotic spindle organization GO:0007052 220 0.037
establishment of protein localization GO:0045184 163 0.037
positive regulation of cell communication GO:0010647 250 0.036
death GO:0016265 284 0.036
regulation of molecular function GO:0065009 217 0.035
vesicle mediated transport GO:0016192 381 0.034
mesenchymal cell development GO:0014031 1 0.034
cell adhesion GO:0007155 136 0.033
meiosis i GO:0007127 59 0.033
central nervous system development GO:0007417 201 0.032
response to bacterium GO:0009617 198 0.032
covalent chromatin modification GO:0016569 106 0.032
chromatin modification GO:0016568 147 0.031
single organism catabolic process GO:0044712 228 0.030
phosphorylation GO:0016310 294 0.030
chromosome segregation GO:0007059 157 0.030
gene silencing GO:0016458 138 0.030
g2 dna damage checkpoint GO:0031572 69 0.030
protein localization GO:0008104 284 0.029
mitotic dna damage checkpoint GO:0044773 74 0.029
organic substance catabolic process GO:1901575 308 0.029
cellular macromolecule localization GO:0070727 220 0.029
embryonic development via the syncytial blastoderm GO:0001700 148 0.028
Fly
positive regulation of multicellular organismal process GO:0051240 143 0.028
stem cell maintenance GO:0019827 67 0.028
positive regulation of nucleic acid templated transcription GO:1903508 266 0.027
negative regulation of rna biosynthetic process GO:1902679 240 0.027
response to sterol GO:0036314 34 0.027
negative regulation of gene expression epigenetic GO:0045814 77 0.026
apoptotic process GO:0006915 159 0.026
positive regulation of immune response GO:0050778 63 0.026
cellular response to hormone stimulus GO:0032870 44 0.025
regulation of phosphorus metabolic process GO:0051174 210 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.025
neuron projection guidance GO:0097485 241 0.025
cellular response to dna damage stimulus GO:0006974 223 0.025
dna integrity checkpoint GO:0031570 81 0.025
camera type eye development GO:0043010 4 0.025
mitotic sister chromatid segregation GO:0000070 87 0.025
imaginal disc derived appendage morphogenesis GO:0035114 395 0.024
dendrite development GO:0016358 204 0.024
Fly
negative regulation of programmed cell death GO:0043069 72 0.024
regulation of dna metabolic process GO:0051052 34 0.024
mrna processing GO:0006397 104 0.023
regulation of growth GO:0040008 233 0.023
regulation of transport GO:0051049 181 0.023
cellular protein localization GO:0034613 160 0.023
chromatin silencing GO:0006342 76 0.023
intracellular signal transduction GO:0035556 300 0.022
regulation of dna templated transcription elongation GO:0032784 17 0.022
defense response to bacterium GO:0042742 178 0.022
taxis GO:0042330 304 0.022
protein modification process GO:0036211 438 0.022
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.022
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.021
multicellular organismal reproductive behavior GO:0033057 110 0.021
regulation of anatomical structure morphogenesis GO:0022603 242 0.021
regulation of protein metabolic process GO:0051246 256 0.020
posttranscriptional regulation of gene expression GO:0010608 145 0.020
negative regulation of rna metabolic process GO:0051253 251 0.020
programmed cell death GO:0012501 257 0.020
positive regulation of protein modification process GO:0031401 58 0.020
cellular response to lipid GO:0071396 20 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.019
cellular response to ketone GO:1901655 17 0.019
intracellular transport GO:0046907 228 0.019
cellular response to organic cyclic compound GO:0071407 32 0.019
development of primary sexual characteristics GO:0045137 50 0.019
positive regulation of rna biosynthetic process GO:1902680 266 0.019
cellular ketone metabolic process GO:0042180 24 0.019
positive regulation of multi organism process GO:0043902 40 0.019
negative regulation of immune system process GO:0002683 50 0.019
negative regulation of cellular biosynthetic process GO:0031327 277 0.019
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.019
response to lipid GO:0033993 38 0.019
protein complex biogenesis GO:0070271 201 0.018
establishment or maintenance of cell polarity GO:0007163 167 0.018
regulation of developmental growth GO:0048638 174 0.018
autophagy GO:0006914 108 0.018
cell fate specification GO:0001708 71 0.018
dendrite morphogenesis GO:0048813 199 0.018
Fly
larval development GO:0002164 104 0.018
Worm
regulation of protein modification process GO:0031399 112 0.017
genitalia development GO:0048806 26 0.017
endomembrane system organization GO:0010256 119 0.017
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.017
response to organic cyclic compound GO:0014070 89 0.017
negative regulation of cellular component organization GO:0051129 108 0.017
regulation of cellular localization GO:0060341 136 0.017
response to ecdysone GO:0035075 34 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.017
regulation of apoptotic process GO:0042981 130 0.016
neural precursor cell proliferation GO:0061351 75 0.016
Fly
defense response to gram negative bacterium GO:0050829 94 0.016
meiotic cell cycle GO:0051321 171 0.016
positive regulation of cellular component biogenesis GO:0044089 80 0.016
regulation of mrna metabolic process GO:1903311 72 0.016
negative regulation of apoptotic process GO:0043066 63 0.016
developmental maturation GO:0021700 172 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
phagocytosis GO:0006909 215 0.015
embryonic organ development GO:0048568 50 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.015
regulation of cellular response to stress GO:0080135 89 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
rna splicing via transesterification reactions GO:0000375 73 0.015
neurological system process GO:0050877 358 0.015
innate immune response GO:0045087 144 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.014
Worm
negative regulation of biosynthetic process GO:0009890 277 0.014
renal tubule development GO:0061326 64 0.014
gland morphogenesis GO:0022612 145 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
salivary gland development GO:0007431 162 0.013
ncrna metabolic process GO:0034660 43 0.013
formation of a compartment boundary GO:0060288 4 0.013
brain development GO:0007420 120 0.013
cellular response to growth factor stimulus GO:0071363 30 0.013
protein secretion GO:0009306 45 0.013
histone lysine demethylation GO:0070076 6 0.013
mitochondrial membrane organization GO:0007006 3 0.013
compound eye morphogenesis GO:0001745 249 0.013
embryonic morphogenesis GO:0048598 206 0.013
growth GO:0040007 359 0.013
regulation of hemocyte proliferation GO:0035206 37 0.012
negative regulation of mitotic cell cycle GO:0045930 109 0.012
sex differentiation GO:0007548 81 0.012
muscle organ development GO:0007517 127 0.012
Fly
positive regulation of signal transduction GO:0009967 223 0.012
response to abiotic stimulus GO:0009628 341 0.012
rna catabolic process GO:0006401 37 0.012
negative regulation of toll signaling pathway GO:0045751 7 0.012
meiotic cell cycle process GO:1903046 132 0.012
secretion by cell GO:0032940 101 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
multi organism reproductive behavior GO:0044705 121 0.012
negative regulation of cell cycle GO:0045786 116 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.011
response to ketone GO:1901654 34 0.011
regulation of proteolysis GO:0030162 87 0.011
salivary gland morphogenesis GO:0007435 145 0.011
regulation of programmed cell death GO:0043067 152 0.011
stem cell proliferation GO:0072089 88 0.011
Fly
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.011
positive regulation of signaling GO:0023056 243 0.011
negative regulation of cell death GO:0060548 81 0.011
rna 3 end processing GO:0031123 45 0.011
regulation of cell cycle GO:0051726 291 0.011
Fly
digestive tract morphogenesis GO:0048546 127 0.011
axon guidance GO:0007411 233 0.011
positive regulation of molecular function GO:0044093 136 0.010
eye morphogenesis GO:0048592 260 0.010
positive regulation of epidermal growth factor activated receptor activity GO:0045741 1 0.010
body morphogenesis GO:0010171 2 0.010
cell cycle g1 s phase transition GO:0044843 31 0.010
heart development GO:0007507 82 0.010

Sfmbt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011