Drosophila melanogaster

0 known processes

MICAL-like (Dmel_CG11259)

CG11259 gene product from transcript CG11259-RA

(Aliases: AAK93415,Dmel\CG11259,CG11259)

MICAL-like biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of macromolecule metabolic process GO:0010604 405 0.257
cellular macromolecule localization GO:0070727 220 0.178
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.158
negative regulation of gene expression GO:0010629 387 0.136
vesicle mediated transport GO:0016192 381 0.122
Human
positive regulation of rna metabolic process GO:0051254 271 0.114
establishment of localization in cell GO:0051649 402 0.113
Human
carbohydrate derivative metabolic process GO:1901135 217 0.110
purine nucleoside triphosphate catabolic process GO:0009146 108 0.110
purine ribonucleoside catabolic process GO:0046130 112 0.105
single organism intracellular transport GO:1902582 207 0.104
Human
organic cyclic compound catabolic process GO:1901361 168 0.101
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.099
endocytosis GO:0006897 310 0.098
Human
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.095
purine nucleoside catabolic process GO:0006152 112 0.094
actin cytoskeleton organization GO:0030036 206 0.093
positive regulation of catalytic activity GO:0043085 118 0.088
negative regulation of cellular biosynthetic process GO:0031327 277 0.084
positive regulation of cellular biosynthetic process GO:0031328 316 0.080
positive regulation of gene expression GO:0010628 290 0.079
positive regulation of transcription dna templated GO:0045893 266 0.075
cellular catabolic process GO:0044248 372 0.072
glycosyl compound catabolic process GO:1901658 112 0.069
cell adhesion GO:0007155 136 0.068
positive regulation of biosynthetic process GO:0009891 316 0.067
nucleobase containing compound catabolic process GO:0034655 165 0.066
regulation of cytoskeleton organization GO:0051493 89 0.066
nucleoside phosphate catabolic process GO:1901292 110 0.065
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.064
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.064
negative regulation of rna metabolic process GO:0051253 251 0.064
morphogenesis of an epithelium GO:0002009 276 0.064
nucleoside metabolic process GO:0009116 127 0.064
ribonucleoside catabolic process GO:0042454 112 0.061
ribonucleoside triphosphate catabolic process GO:0009203 108 0.060
single organism membrane organization GO:0044802 93 0.059
Human
extracellular structure organization GO:0043062 46 0.057
cellular nitrogen compound catabolic process GO:0044270 165 0.056
protein localization GO:0008104 284 0.055
Human
macromolecular complex assembly GO:0065003 256 0.055
catabolic process GO:0009056 409 0.054
nucleoside phosphate metabolic process GO:0006753 162 0.053
heterocycle catabolic process GO:0046700 166 0.053
positive regulation of molecular function GO:0044093 136 0.053
positive regulation of nucleic acid templated transcription GO:1903508 266 0.051
cellular protein localization GO:0034613 160 0.051
Human
purine nucleotide catabolic process GO:0006195 109 0.051
positive regulation of catabolic process GO:0009896 105 0.051
growth GO:0040007 359 0.050
carbohydrate derivative catabolic process GO:1901136 118 0.049
compound eye development GO:0048749 307 0.049
morphogenesis of embryonic epithelium GO:0016331 94 0.049
positive regulation of response to stimulus GO:0048584 323 0.049
nucleotide catabolic process GO:0009166 109 0.047
biological adhesion GO:0022610 138 0.046
nucleotide metabolic process GO:0009117 161 0.046
cell cell signaling involved in cell fate commitment GO:0045168 210 0.046
positive regulation of cellular component biogenesis GO:0044089 80 0.046
purine nucleoside metabolic process GO:0042278 127 0.044
protein transport GO:0015031 155 0.044
Human
positive regulation of hydrolase activity GO:0051345 78 0.044
positive regulation of rna biosynthetic process GO:1902680 266 0.043
nucleobase containing small molecule metabolic process GO:0055086 174 0.043
organic substance transport GO:0071702 257 0.042
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.042
ribonucleotide metabolic process GO:0009259 145 0.041
transcription from rna polymerase ii promoter GO:0006366 368 0.041
aromatic compound catabolic process GO:0019439 166 0.040
organophosphate metabolic process GO:0019637 195 0.039
organonitrogen compound metabolic process GO:1901564 318 0.039
negative regulation of transcription dna templated GO:0045892 237 0.039
purine containing compound catabolic process GO:0072523 112 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.039
regulation of cell cycle GO:0051726 291 0.038
organic substance catabolic process GO:1901575 308 0.038
organophosphate catabolic process GO:0046434 112 0.038
nucleoside catabolic process GO:0009164 112 0.038
regulation of multicellular organismal development GO:2000026 414 0.038
purine nucleotide metabolic process GO:0006163 146 0.038
positive regulation of nucleoside metabolic process GO:0045979 47 0.037
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.037
regulation of molecular function GO:0065009 217 0.036
organonitrogen compound catabolic process GO:1901565 128 0.036
wing disc morphogenesis GO:0007472 344 0.036
phagocytosis GO:0006909 215 0.036
single organism catabolic process GO:0044712 228 0.036
regulation of protein metabolic process GO:0051246 256 0.035
negative regulation of biosynthetic process GO:0009890 277 0.034
regulation of hydrolase activity GO:0051336 97 0.034
regulation of cell differentiation GO:0045595 302 0.034
gastrulation involving germ band extension GO:0010004 36 0.034
immune system process GO:0002376 347 0.034
regulation of anatomical structure size GO:0090066 163 0.033
intracellular signal transduction GO:0035556 300 0.033
regulation of immune effector process GO:0002697 52 0.032
immune effector process GO:0002252 98 0.032
regulation of cell shape GO:0008360 113 0.032
actin filament based process GO:0030029 220 0.032
protein modification process GO:0036211 438 0.032
gtp catabolic process GO:0006184 72 0.032
positive regulation of signaling GO:0023056 243 0.032
regulation of cell morphogenesis GO:0022604 163 0.032
regulation of organelle organization GO:0033043 196 0.031
positive regulation of protein metabolic process GO:0051247 128 0.031
membrane organization GO:0061024 112 0.031
Human
response to organic substance GO:0010033 284 0.031
guanosine containing compound catabolic process GO:1901069 74 0.030
cellular protein modification process GO:0006464 438 0.030
endomembrane system organization GO:0010256 119 0.030
Human
purine ribonucleotide metabolic process GO:0009150 145 0.030
lateral inhibition GO:0046331 206 0.029
nuclear division GO:0000280 332 0.029
ribonucleoside triphosphate metabolic process GO:0009199 119 0.029
positive regulation of cell communication GO:0010647 250 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.029
imaginal disc derived appendage development GO:0048737 399 0.029
nucleoside triphosphate metabolic process GO:0009141 120 0.029
regulation of anatomical structure morphogenesis GO:0022603 242 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.029
purine ribonucleotide catabolic process GO:0009154 109 0.028
purine nucleoside triphosphate metabolic process GO:0009144 119 0.028
cellular response to dna damage stimulus GO:0006974 223 0.028
ribose phosphate metabolic process GO:0019693 145 0.028
regulation of catalytic activity GO:0050790 185 0.028
small molecule metabolic process GO:0044281 305 0.027
regulation of cell development GO:0060284 215 0.027
regulation of gtpase activity GO:0043087 44 0.027
positive regulation of phosphorus metabolic process GO:0010562 139 0.027
regulation of cell cycle process GO:0010564 181 0.026
defense response to gram negative bacterium GO:0050829 94 0.026
regulation of catabolic process GO:0009894 170 0.026
ribonucleoside metabolic process GO:0009119 127 0.025
open tracheal system development GO:0007424 204 0.025
regulation of intracellular signal transduction GO:1902531 236 0.025
g protein coupled receptor signaling pathway GO:0007186 136 0.025
translation GO:0006412 69 0.024
molting cycle GO:0042303 56 0.024
single organism membrane fusion GO:0044801 42 0.024
negative regulation of cellular metabolic process GO:0031324 382 0.024
cell death GO:0008219 279 0.024
nucleoside triphosphate catabolic process GO:0009143 108 0.023
regulation of phosphate metabolic process GO:0019220 210 0.023
purine containing compound metabolic process GO:0072521 155 0.023
positive regulation of gtp catabolic process GO:0033126 43 0.023
positive regulation of ras gtpase activity GO:0032320 36 0.023
regulation of small gtpase mediated signal transduction GO:0051056 93 0.023
intracellular transport GO:0046907 228 0.023
Human
ribonucleotide catabolic process GO:0009261 109 0.023
protein complex assembly GO:0006461 200 0.022
response to oxygen containing compound GO:1901700 200 0.022
regulation of cell adhesion GO:0030155 27 0.022
positive regulation of signal transduction GO:0009967 223 0.022
eye photoreceptor cell differentiation GO:0001754 145 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.022
regulation of purine nucleotide metabolic process GO:1900542 62 0.022
positive regulation of cellular catabolic process GO:0031331 95 0.022
developmental maturation GO:0021700 172 0.022
protein complex biogenesis GO:0070271 201 0.022
regulation of nucleotide metabolic process GO:0006140 62 0.021
regulation of cellular component size GO:0032535 98 0.021
phosphorylation GO:0016310 294 0.021
regulation of cell death GO:0010941 173 0.021
establishment of protein localization GO:0045184 163 0.021
Human
regulation of growth GO:0040008 233 0.021
developmental programmed cell death GO:0010623 138 0.021
cellular response to extracellular stimulus GO:0031668 64 0.021
regulation of nucleotide catabolic process GO:0030811 48 0.021
photoreceptor cell differentiation GO:0046530 170 0.021
glycosyl compound metabolic process GO:1901657 127 0.021
purine ribonucleoside metabolic process GO:0046128 127 0.020
establishment or maintenance of cell polarity GO:0007163 167 0.020
compound eye morphogenesis GO:0001745 249 0.020
cellularization GO:0007349 90 0.020
negative regulation of developmental process GO:0051093 201 0.020
organelle fission GO:0048285 340 0.020
neurological system process GO:0050877 358 0.019
response to abiotic stimulus GO:0009628 341 0.019
regulation of immune response GO:0050776 118 0.019
regulation of nucleoside metabolic process GO:0009118 50 0.019
programmed cell death GO:0012501 257 0.019
cellular response to chemical stimulus GO:0070887 199 0.019
single organism biosynthetic process GO:0044711 206 0.019
tissue morphogenesis GO:0048729 297 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.019
actin filament bundle organization GO:0061572 28 0.019
small gtpase mediated signal transduction GO:0007264 88 0.018
gland morphogenesis GO:0022612 145 0.018
embryonic morphogenesis GO:0048598 206 0.018
sensory organ morphogenesis GO:0090596 260 0.018
regulation of cellular component biogenesis GO:0044087 201 0.018
appendage morphogenesis GO:0035107 397 0.018
regulation of gtp catabolic process GO:0033124 44 0.018
gland development GO:0048732 191 0.017
cellular response to nutrient levels GO:0031669 62 0.017
body morphogenesis GO:0010171 2 0.017
regulation of rab protein signal transduction GO:0032483 7 0.017
regulation of response to stress GO:0080134 200 0.017
aging GO:0007568 143 0.017
regulation of actin cytoskeleton organization GO:0032956 42 0.017
cellular response to external stimulus GO:0071496 66 0.017
actin filament organization GO:0007015 126 0.017
regulation of translation GO:0006417 56 0.017
response to endogenous stimulus GO:0009719 119 0.017
positive regulation of cellular component organization GO:0051130 156 0.016
regulation of localization GO:0032879 275 0.016
guanosine containing compound metabolic process GO:1901068 74 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.016
exocrine system development GO:0035272 162 0.016
positive regulation of phosphate metabolic process GO:0045937 139 0.016
single organism behavior GO:0044708 391 0.016
morphogenesis of a polarized epithelium GO:0001738 93 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
positive regulation of endopeptidase activity GO:0010950 26 0.016
regulation of establishment of protein localization GO:0070201 61 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.015
proteolysis GO:0006508 192 0.015
ras protein signal transduction GO:0007265 88 0.015
cell growth GO:0016049 108 0.015
cell proliferation GO:0008283 299 0.015
spindle organization GO:0007051 253 0.015
positive regulation of multicellular organismal process GO:0051240 143 0.015
regulation of notch signaling pathway GO:0008593 100 0.015
gtp metabolic process GO:0046039 72 0.015
actomyosin structure organization GO:0031032 56 0.015
secretion GO:0046903 109 0.015
regulation of membrane potential GO:0042391 35 0.015
extracellular matrix organization GO:0030198 32 0.015
non sensory hair organization GO:0035316 47 0.015
respiratory system development GO:0060541 213 0.015
cytoplasmic transport GO:0016482 130 0.015
regulation of purine nucleotide catabolic process GO:0033121 48 0.015
appendage development GO:0048736 401 0.015
death GO:0016265 284 0.015
cellular amide metabolic process GO:0043603 80 0.015
cell fate determination GO:0001709 91 0.014
taxis GO:0042330 304 0.014
antimicrobial humoral response GO:0019730 99 0.014
actin filament based movement GO:0030048 26 0.014
regulation of cellular localization GO:0060341 136 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
positive regulation of cell motility GO:2000147 3 0.014
embryonic pattern specification GO:0009880 174 0.014
positive regulation of response to external stimulus GO:0032103 44 0.014
wnt signaling pathway GO:0016055 98 0.014
negative regulation of rna biosynthetic process GO:1902679 240 0.014
regulation of cell substrate adhesion GO:0010810 2 0.014
kidney morphogenesis GO:0060993 3 0.014
response to oxidative stress GO:0006979 86 0.014
mitotic spindle organization GO:0007052 220 0.013
response to organic cyclic compound GO:0014070 89 0.013
regulation of transport GO:0051049 181 0.013
response to biotic stimulus GO:0009607 294 0.013
regulation of phosphorylation GO:0042325 147 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
regulation of neuron differentiation GO:0045664 103 0.013
oocyte differentiation GO:0009994 145 0.013
positive regulation of cell adhesion GO:0045785 10 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
cellular response to organic substance GO:0071310 132 0.013
establishment of organelle localization GO:0051656 122 0.013
immune response GO:0006955 246 0.013
gastrulation with mouth forming first GO:0001703 36 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.013
regulation of programmed cell death GO:0043067 152 0.013
oocyte axis specification GO:0007309 108 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
regulation of nervous system development GO:0051960 248 0.013
regulation of ras protein signal transduction GO:0046578 93 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
molting cycle chitin based cuticle GO:0007591 56 0.012
protein polymerization GO:0051258 42 0.012
dorsal closure GO:0007391 79 0.012
single organism cellular localization GO:1902580 180 0.012
Human
negative regulation of multicellular organismal process GO:0051241 142 0.012
innate immune response GO:0045087 144 0.012
actin filament bundle assembly GO:0051017 26 0.012
striated muscle cell differentiation GO:0051146 90 0.012
cation transport GO:0006812 110 0.012
axon development GO:0061564 297 0.012
protein processing GO:0016485 68 0.012
salivary gland morphogenesis GO:0007435 145 0.012
positive regulation of nucleotide catabolic process GO:0030813 46 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
protein phosphorylation GO:0006468 169 0.012
autophagy GO:0006914 108 0.012
regulation of intracellular transport GO:0032386 64 0.012
organelle fusion GO:0048284 46 0.012
positive regulation of nucleotide metabolic process GO:0045981 55 0.012
cellular homeostasis GO:0019725 80 0.011
positive regulation of gtpase activity GO:0043547 43 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
regulation of protein transport GO:0051223 57 0.011
positive regulation of intracellular transport GO:0032388 42 0.011
multi organism behavior GO:0051705 175 0.011
salivary gland development GO:0007431 162 0.011
defense response to other organism GO:0098542 225 0.011
cell recognition GO:0008037 102 0.011
localization of cell GO:0051674 257 0.011
eye development GO:0001654 323 0.011
wound healing GO:0042060 75 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.011
humoral immune response GO:0006959 117 0.011
organelle assembly GO:0070925 198 0.011
positive regulation of developmental process GO:0051094 143 0.011
regulation of vesicle mediated transport GO:0060627 59 0.011
response to nutrient levels GO:0031667 114 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
activation of cysteine type endopeptidase activity GO:0097202 17 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
synapse organization GO:0050808 196 0.010
spindle elongation GO:0051231 83 0.010
negative regulation of mitotic cell cycle GO:0045930 109 0.010
golgi vesicle transport GO:0048193 27 0.010
organelle membrane fusion GO:0090174 16 0.010
response to hydrogen peroxide GO:0042542 11 0.010
positive regulation of protein transport GO:0051222 37 0.010
response to external biotic stimulus GO:0043207 293 0.010
cell division GO:0051301 248 0.010
response to organonitrogen compound GO:0010243 75 0.010
endosomal transport GO:0016197 44 0.010
Human
regulation of cellular amide metabolic process GO:0034248 39 0.010
regulation of actin filament length GO:0030832 27 0.010
skeletal muscle fiber development GO:0048741 3 0.010
centrosome organization GO:0051297 163 0.010
meiotic nuclear division GO:0007126 151 0.010

MICAL-like disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.068
nervous system disease DOID:863 0 0.020
central nervous system disease DOID:331 0 0.013