Drosophila melanogaster

52 known processes

Ace (Dmel_CG17907)

Acetylcholine esterase

(Aliases: AcChE,CHE,ACE,l(3)87Ed,dAChE,ache,FBgn0000024,ace,l(3)26,CG17907,dmAChE,DmAChE,AchE,AChE,Dmel\CG17907)

Ace biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
adult behavior GO:0030534 137 0.966
male mating behavior GO:0060179 70 0.880
Fly
male courtship behavior veined wing generated song production GO:0045433 20 0.830
cation transport GO:0006812 110 0.812
adult locomotory behavior GO:0008344 76 0.806
cation transmembrane transport GO:0098655 88 0.784
single organism behavior GO:0044708 391 0.728
response to temperature stimulus GO:0009266 106 0.710
negative regulation of cellular metabolic process GO:0031324 382 0.690
negative regulation of biosynthetic process GO:0009890 277 0.643
regulation of transmembrane transport GO:0034762 27 0.609
response to monosaccharide GO:0034284 4 0.590
metal ion transport GO:0030001 74 0.574
courtship behavior GO:0007619 68 0.540
positive regulation of transport GO:0051050 92 0.506
homeostatic process GO:0042592 199 0.493
locomotory behavior GO:0007626 176 0.486
mating GO:0007618 120 0.483
Fly
reproductive behavior GO:0019098 122 0.480
Fly
ion transmembrane transport GO:0034220 122 0.479
transmembrane transport GO:0055085 139 0.478
regulation of localization GO:0032879 275 0.475
signal release GO:0023061 49 0.474
response to oxygen containing compound GO:1901700 200 0.473
Zebrafish
regulation of phosphate metabolic process GO:0019220 210 0.452
male courtship behavior veined wing vibration GO:0016545 21 0.417
negative regulation of cellular biosynthetic process GO:0031327 277 0.414
regulation of phosphorus metabolic process GO:0051174 210 0.401
positive regulation of macromolecule metabolic process GO:0010604 405 0.398
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.382
regulation of synaptic transmission GO:0050804 69 0.378
neurological system process GO:0050877 358 0.355
regulation of protein metabolic process GO:0051246 256 0.353
inorganic cation transmembrane transport GO:0098662 61 0.353
regulation of multicellular organismal development GO:2000026 414 0.347
synaptic transmission GO:0007268 288 0.340
response to glucose GO:0009749 2 0.331
chemical homeostasis GO:0048878 92 0.323
cognition GO:0050890 141 0.323
response to abiotic stimulus GO:0009628 341 0.317
phosphorylation GO:0016310 294 0.317
sensory perception GO:0007600 196 0.307
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.307
monovalent inorganic cation transport GO:0015672 40 0.305
regulation of transport GO:0051049 181 0.299
sleep GO:0030431 49 0.295
organonitrogen compound metabolic process GO:1901564 318 0.292
negative regulation of rna biosynthetic process GO:1902679 240 0.288
regulation of apoptotic process GO:0042981 130 0.287
regulation of molecular function GO:0065009 217 0.286
male courtship behavior veined wing extension GO:0048065 22 0.267
membrane depolarization GO:0051899 4 0.262
regulation of cellular localization GO:0060341 136 0.257
cation homeostasis GO:0055080 51 0.255
negative regulation of rna metabolic process GO:0051253 251 0.253
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.249
organophosphate metabolic process GO:0019637 195 0.246
positive regulation of molecular function GO:0044093 136 0.246
positive regulation of phosphorus metabolic process GO:0010562 139 0.240
nucleobase containing small molecule metabolic process GO:0055086 174 0.239
response to organic substance GO:0010033 284 0.228
Zebrafish Fly
cell junction organization GO:0034330 57 0.227
Fly
ion transport GO:0006811 145 0.224
regulation of membrane potential GO:0042391 35 0.223
programmed cell death GO:0012501 257 0.222
cell death GO:0008219 279 0.220
tissue morphogenesis GO:0048729 297 0.211
negative regulation of cell communication GO:0010648 223 0.209
multicellular organismal reproductive behavior GO:0033057 110 0.208
Fly
response to hexose GO:0009746 3 0.205
positive regulation of phosphate metabolic process GO:0045937 139 0.205
negative regulation of nucleic acid templated transcription GO:1903507 240 0.205
cellular chemical homeostasis GO:0055082 40 0.204
cell junction assembly GO:0034329 42 0.203
Fly
cellular ion homeostasis GO:0006873 39 0.200
multi multicellular organism process GO:0044706 123 0.198
Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.198
catabolic process GO:0009056 409 0.197
synapse organization GO:0050808 196 0.195
Zebrafish
death GO:0016265 284 0.186
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.179
intracellular signal transduction GO:0035556 300 0.178
sensory perception of sound GO:0007605 56 0.178
positive regulation of cellular biosynthetic process GO:0031328 316 0.177
detection of light stimulus GO:0009583 58 0.177
cellular metal ion homeostasis GO:0006875 31 0.175
sensory perception of chemical stimulus GO:0007606 116 0.174
neurotransmitter transport GO:0006836 37 0.172
carbohydrate derivative metabolic process GO:1901135 217 0.170
chemotaxis GO:0006935 249 0.169
Fly
cellular response to heat GO:0034605 24 0.166
metal ion homeostasis GO:0055065 44 0.166
sensory perception of mechanical stimulus GO:0050954 72 0.164
response to heat GO:0009408 63 0.164
cellular response to oxygen containing compound GO:1901701 79 0.163
Zebrafish
response to carbohydrate GO:0009743 15 0.162
ion homeostasis GO:0050801 55 0.159
cellular response to organic substance GO:0071310 132 0.157
Zebrafish
cellular response to chemical stimulus GO:0070887 199 0.150
Zebrafish
regulation of ion transport GO:0043269 39 0.145
heart process GO:0003015 37 0.145
single organism biosynthetic process GO:0044711 206 0.142
negative regulation of transcription dna templated GO:0045892 237 0.142
positive regulation of biosynthetic process GO:0009891 316 0.140
nucleotide metabolic process GO:0009117 161 0.135
organonitrogen compound catabolic process GO:1901565 128 0.135
cell maturation GO:0048469 144 0.134
regulation of neurotransmitter levels GO:0001505 38 0.131
regulation of multi organism process GO:0043900 131 0.131
phototransduction visible light GO:0007603 27 0.130
regulation of protein modification process GO:0031399 112 0.130
nucleoside phosphate metabolic process GO:0006753 162 0.129
cellular amino acid metabolic process GO:0006520 61 0.127
cellular ketone metabolic process GO:0042180 24 0.127
regulation of cellular ketone metabolic process GO:0010565 3 0.126
regulation of metal ion transport GO:0010959 15 0.125
apoptotic process GO:0006915 159 0.125
learning or memory GO:0007611 141 0.124
epithelial cell development GO:0002064 274 0.122
Fly
ribose phosphate metabolic process GO:0019693 145 0.122
small molecule metabolic process GO:0044281 305 0.121
cell division GO:0051301 248 0.120
response to mechanical stimulus GO:0009612 28 0.118
regulation of cell differentiation GO:0045595 302 0.116
regulation of cellular protein metabolic process GO:0032268 243 0.115
immune effector process GO:0002252 98 0.115
actin filament based movement GO:0030048 26 0.115
regulation of protein phosphorylation GO:0001932 64 0.111
inorganic ion transmembrane transport GO:0098660 73 0.111
response to radiation GO:0009314 155 0.111
regulation of system process GO:0044057 36 0.107
g protein coupled receptor signaling pathway GO:0007186 136 0.107
regulation of neurotransmitter secretion GO:0046928 14 0.106
epithelial cell differentiation GO:0030855 322 0.106
Fly
regulation of secretion GO:0051046 44 0.105
negative regulation of signal transduction GO:0009968 206 0.104
heart development GO:0007507 82 0.101
Fly
nucleoside triphosphate metabolic process GO:0009141 120 0.100
heart morphogenesis GO:0003007 32 0.099
Fly
regulation of phosphorylation GO:0042325 147 0.099
response to nitrogen compound GO:1901698 90 0.097
Zebrafish
imaginal disc derived wing morphogenesis GO:0007476 337 0.097
Fly
transcription from rna polymerase ii promoter GO:0006366 368 0.096
amino acid transport GO:0006865 12 0.095
regulation of programmed cell death GO:0043067 152 0.095
protein modification process GO:0036211 438 0.094
multicellular organismal aging GO:0010259 140 0.094
Fly
single organism catabolic process GO:0044712 228 0.094
associative learning GO:0008306 65 0.093
cell cell junction assembly GO:0007043 38 0.093
Fly
cellular macromolecule localization GO:0070727 220 0.093
secretion GO:0046903 109 0.092
regulation of anatomical structure morphogenesis GO:0022603 242 0.091
negative regulation of gene expression GO:0010629 387 0.091
neurotransmitter metabolic process GO:0042133 2 0.089
developmental growth GO:0048589 280 0.088
regulation of cell morphogenesis GO:0022604 163 0.087
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.087
establishment of localization in cell GO:0051649 402 0.087
embryonic morphogenesis GO:0048598 206 0.087
positive regulation of protein metabolic process GO:0051247 128 0.086
learning GO:0007612 75 0.086
purine containing compound metabolic process GO:0072521 155 0.083
regulation of cell development GO:0060284 215 0.083
carboxylic acid metabolic process GO:0019752 92 0.083
pigment metabolic process GO:0042440 84 0.083
mapk cascade GO:0000165 107 0.082
vesicle mediated transport GO:0016192 381 0.082
Mouse
chromatin silencing GO:0006342 76 0.082
hindbrain development GO:0030902 2 0.082
nitrogen compound transport GO:0071705 85 0.082
regulation of intracellular signal transduction GO:1902531 236 0.082
circulatory system development GO:0072359 82 0.081
Fly
cellular cation homeostasis GO:0030003 38 0.081
localization of cell GO:0051674 257 0.081
Fly
detection of visible light GO:0009584 38 0.079
regulation of nervous system development GO:0051960 248 0.077
regulation of nucleotide metabolic process GO:0006140 62 0.076
response to light stimulus GO:0009416 124 0.076
axonogenesis GO:0007409 290 0.075
Fly
oxidation reduction process GO:0055114 123 0.075
signal transduction by phosphorylation GO:0023014 107 0.074
response to oxidative stress GO:0006979 86 0.072
purine nucleotide catabolic process GO:0006195 109 0.072
developmental maturation GO:0021700 172 0.071
regulation of response to stress GO:0080134 200 0.069
cellular amine metabolic process GO:0044106 12 0.069
positive regulation of gene expression GO:0010628 290 0.068
male courtship behavior GO:0008049 63 0.067
endocytosis GO:0006897 310 0.067
Mouse
negative regulation of response to stimulus GO:0048585 258 0.066
positive regulation of cellular protein metabolic process GO:0032270 118 0.066
divalent metal ion transport GO:0070838 26 0.065
cell motility GO:0048870 251 0.065
Fly
sensory organ morphogenesis GO:0090596 260 0.064
multi organism reproductive behavior GO:0044705 121 0.064
Fly
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.064
regulation of catabolic process GO:0009894 170 0.063
imaginal disc derived appendage morphogenesis GO:0035114 395 0.063
Fly
response to organic cyclic compound GO:0014070 89 0.063
axon development GO:0061564 297 0.062
Fly
appendage development GO:0048736 401 0.062
Fly
regulation of catalytic activity GO:0050790 185 0.062
negative regulation of signaling GO:0023057 219 0.061
calcium ion homeostasis GO:0055074 23 0.061
aging GO:0007568 143 0.061
Fly
dendrite morphogenesis GO:0048813 199 0.060
oxoacid metabolic process GO:0043436 103 0.059
purine ribonucleoside metabolic process GO:0046128 127 0.059
gene silencing GO:0016458 138 0.058
actin filament based process GO:0030029 220 0.057
Zebrafish
cell proliferation GO:0008283 299 0.056
positive regulation of catalytic activity GO:0043085 118 0.056
detection of stimulus GO:0051606 156 0.055
regulation of oocyte development GO:0060281 27 0.055
regulation of behavior GO:0050795 75 0.054
response to ethanol GO:0045471 59 0.053
Zebrafish
multi organism behavior GO:0051705 175 0.053
Fly
morphogenesis of an epithelium GO:0002009 276 0.053
positive regulation of signaling GO:0023056 243 0.052
heart contraction GO:0060047 26 0.052
positive regulation of secretion GO:0051047 22 0.052
organic substance transport GO:0071702 257 0.052
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.052
enzyme linked receptor protein signaling pathway GO:0007167 179 0.051
tube development GO:0035295 244 0.051
response to extracellular stimulus GO:0009991 116 0.051
amine metabolic process GO:0009308 12 0.051
ribonucleotide metabolic process GO:0009259 145 0.050
purine ribonucleotide metabolic process GO:0009150 145 0.050
positive regulation of nucleotide metabolic process GO:0045981 55 0.049
positive regulation of transcription dna templated GO:0045893 266 0.049
regulation of circadian rhythm GO:0042752 49 0.049
ectodermal placode development GO:0071696 4 0.047
lipid metabolic process GO:0006629 121 0.047
oocyte maturation GO:0001556 3 0.047
regulation of hormone levels GO:0010817 40 0.047
cellular lipid metabolic process GO:0044255 83 0.047
cellular homeostasis GO:0019725 80 0.047
immune system process GO:0002376 347 0.047
regulation of mapk cascade GO:0043408 92 0.046
response to inorganic substance GO:0010035 44 0.044
regulation of neurogenesis GO:0050767 158 0.044
carbohydrate homeostasis GO:0033500 12 0.044
behavioral response to ethanol GO:0048149 49 0.044
carbohydrate derivative biosynthetic process GO:1901137 85 0.044
divalent inorganic cation homeostasis GO:0072507 29 0.044
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.044
protein phosphorylation GO:0006468 169 0.043
regulation of cellular amine metabolic process GO:0033238 3 0.043
organic acid transport GO:0015849 18 0.042
regulation of immune system process GO:0002682 176 0.042
divalent inorganic cation transport GO:0072511 30 0.042
regulation of organelle organization GO:0033043 196 0.042
defense response GO:0006952 300 0.041
Fly
phagocytosis GO:0006909 215 0.041
regulation of neuron differentiation GO:0045664 103 0.041
positive regulation of rna metabolic process GO:0051254 271 0.041
positive regulation of response to stimulus GO:0048584 323 0.041
chromatin silencing at centromere GO:0030702 3 0.041
positive regulation of phosphorylation GO:0042327 87 0.040
negative regulation of gene expression epigenetic GO:0045814 77 0.040
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.040
thermotaxis GO:0043052 16 0.040
l glutamate import GO:0051938 1 0.039
response to organophosphorus GO:0046683 2 0.039
Fly
positive regulation of cell communication GO:0010647 250 0.039
purine nucleoside triphosphate metabolic process GO:0009144 119 0.039
regulation of cell death GO:0010941 173 0.039
cellular calcium ion homeostasis GO:0006874 21 0.039
imaginal disc derived appendage development GO:0048737 399 0.038
Fly
acid secretion GO:0046717 1 0.038
glial cell development GO:0021782 27 0.038
response to alcohol GO:0097305 95 0.037
Zebrafish
calcium ion transport GO:0006816 24 0.037
positive regulation of cellular catabolic process GO:0031331 95 0.037
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.037
Fly
purine ribonucleoside catabolic process GO:0046130 112 0.037
cellular protein localization GO:0034613 160 0.037
phototransduction GO:0007602 52 0.036
organic acid metabolic process GO:0006082 103 0.036
ameboidal type cell migration GO:0001667 151 0.036
Fly
regulation of gene expression epigenetic GO:0040029 128 0.035
wing disc morphogenesis GO:0007472 344 0.035
Fly
organic cyclic compound catabolic process GO:1901361 168 0.035
cellular nitrogen compound catabolic process GO:0044270 165 0.034
nucleobase containing compound catabolic process GO:0034655 165 0.034
glycosyl compound metabolic process GO:1901657 127 0.034
detection of external stimulus GO:0009581 66 0.034
regulation of cell projection organization GO:0031344 92 0.033
actin mediated cell contraction GO:0070252 21 0.033
immune response regulating signaling pathway GO:0002764 2 0.033
regulation of cellular amino acid metabolic process GO:0006521 0 0.033
positive regulation of nucleic acid templated transcription GO:1903508 266 0.033
regulation of anatomical structure size GO:0090066 163 0.033
Fly
cellular catabolic process GO:0044248 372 0.032
taxis GO:0042330 304 0.032
molting cycle chitin based cuticle GO:0007591 56 0.032
rhythmic process GO:0048511 106 0.032
response to endogenous stimulus GO:0009719 119 0.031
Zebrafish
myotube cell development GO:0014904 3 0.031
regulation of protein kinase activity GO:0045859 51 0.031
positive regulation of protein modification process GO:0031401 58 0.031
purine containing compound catabolic process GO:0072523 112 0.031
cellular protein modification process GO:0006464 438 0.031
regulation of secretion by cell GO:1903530 39 0.030
regulation of purine nucleotide metabolic process GO:1900542 62 0.030
establishment of protein localization GO:0045184 163 0.030
response to nutrient levels GO:0031667 114 0.030
axon guidance GO:0007411 233 0.030
Fly
purine nucleoside metabolic process GO:0042278 127 0.030
regulation of blood circulation GO:1903522 21 0.030
ribonucleoside triphosphate catabolic process GO:0009203 108 0.030
muscle contraction GO:0006936 13 0.030
aromatic compound catabolic process GO:0019439 166 0.030
calcium ion transmembrane transport GO:0070588 17 0.030
positive regulation of immune system process GO:0002684 68 0.030
organonitrogen compound biosynthetic process GO:1901566 117 0.030
body morphogenesis GO:0010171 2 0.029
positive regulation of multicellular organismal process GO:0051240 143 0.029
regulation of cellular component biogenesis GO:0044087 201 0.029
regulation of nucleoside metabolic process GO:0009118 50 0.029
nucleoside metabolic process GO:0009116 127 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.028
molting cycle GO:0042303 56 0.028
positive regulation of protein phosphorylation GO:0001934 34 0.028
purine nucleotide metabolic process GO:0006163 146 0.028
negative regulation of multicellular organismal process GO:0051241 142 0.028
reproductive structure development GO:0048608 74 0.028
heterocycle catabolic process GO:0046700 166 0.027
immune response GO:0006955 246 0.027
regulation of developmental growth GO:0048638 174 0.027
cell cycle phase transition GO:0044770 140 0.027
circulatory system process GO:0003013 37 0.026
establishment of vesicle localization GO:0051650 51 0.026
regulation of embryonic pattern specification GO:1902875 27 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.026
secretion by cell GO:0032940 101 0.026
organic anion transport GO:0015711 28 0.026
anion homeostasis GO:0055081 3 0.026
organelle assembly GO:0070925 198 0.026
Zebrafish
growth GO:0040007 359 0.026
response to hormone GO:0009725 45 0.026
release of sequestered calcium ion into cytosol GO:0051209 1 0.025
maintenance of location GO:0051235 73 0.025
Fly
regulation of cellular catabolic process GO:0031329 157 0.025
post embryonic appendage morphogenesis GO:0035120 385 0.025
Fly
positive regulation of nucleoside metabolic process GO:0045979 47 0.025
response to toxic substance GO:0009636 22 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.025
regulation of notch signaling pathway GO:0008593 100 0.025
oocyte development GO:0048599 124 0.025
regulation of locomotion GO:0040012 42 0.025
Worm
response to wounding GO:0009611 94 0.025
cellular response to radiation GO:0071478 52 0.025
neuron projection guidance GO:0097485 241 0.024
Fly
positive regulation of intracellular signal transduction GO:1902533 116 0.024
monocarboxylic acid transport GO:0015718 3 0.024
positive regulation of hydrolase activity GO:0051345 78 0.024
action potential GO:0001508 13 0.024
ribonucleotide catabolic process GO:0009261 109 0.024
ribonucleoside triphosphate metabolic process GO:0009199 119 0.024
multicellular organismal signaling GO:0035637 12 0.024
cytosolic calcium ion homeostasis GO:0051480 11 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.023
regulation of microtubule based process GO:0032886 49 0.023
regulation of cell maturation GO:1903429 27 0.023
regulation of protein transport GO:0051223 57 0.023
synaptic vesicle exocytosis GO:0016079 16 0.023
cellular response to carbohydrate stimulus GO:0071322 4 0.023
positive regulation of cell migration GO:0030335 2 0.023
endoplasmic reticulum organization GO:0007029 13 0.023
response to external biotic stimulus GO:0043207 293 0.023
Fly
central nervous system development GO:0007417 201 0.023
protein complex biogenesis GO:0070271 201 0.023
Mouse
positive regulation of rna biosynthetic process GO:1902680 266 0.023
response to drug GO:0042493 17 0.023
positive regulation of cell motility GO:2000147 3 0.023
carbohydrate metabolic process GO:0005975 82 0.023
purine ribonucleotide catabolic process GO:0009154 109 0.022
establishment of glial blood brain barrier GO:0060857 14 0.022
ribonucleoside metabolic process GO:0009119 127 0.022
mesenchymal cell differentiation GO:0048762 1 0.022
skeletal muscle organ development GO:0060538 48 0.022
cellular protein complex disassembly GO:0043624 35 0.022
chromatin organization GO:0006325 207 0.022
regulation of apoptotic signaling pathway GO:2001233 10 0.022
epidermis development GO:0008544 65 0.022
Fly
nucleotide catabolic process GO:0009166 109 0.022
cellular response to carbon dioxide GO:0071244 2 0.022
protein complex assembly GO:0006461 200 0.021
Mouse
positive regulation of catabolic process GO:0009896 105 0.021
nucleoside catabolic process GO:0009164 112 0.021
detection of abiotic stimulus GO:0009582 66 0.021
carbohydrate derivative catabolic process GO:1901136 118 0.021
anatomical structure homeostasis GO:0060249 97 0.021
sensory perception of smell GO:0007608 80 0.021
regulation of cell cycle process GO:0010564 181 0.021
compound eye morphogenesis GO:0001745 249 0.021
skeletal muscle tissue development GO:0007519 13 0.021
covalent chromatin modification GO:0016569 106 0.021
ectodermal placode morphogenesis GO:0071697 4 0.021
regulation of neurotransmitter transport GO:0051588 14 0.021
response to other organism GO:0051707 293 0.020
Fly
spermatogenesis GO:0007283 200 0.020
Fly
axis specification GO:0009798 167 0.020
regulation of cellular component movement GO:0051270 42 0.020
detection of chemical stimulus GO:0009593 93 0.020
inositol lipid mediated signaling GO:0048017 4 0.020
cellular macromolecular complex assembly GO:0034622 153 0.020
apoptotic signaling pathway GO:0097190 27 0.020
negative regulation of cell differentiation GO:0045596 143 0.020
wound healing GO:0042060 75 0.020
extrinsic apoptotic signaling pathway GO:0097191 1 0.020
purine nucleoside triphosphate catabolic process GO:0009146 108 0.020
regulation of cellular response to stress GO:0080135 89 0.020
cellular response to dna damage stimulus GO:0006974 223 0.019
ribonucleoside catabolic process GO:0042454 112 0.019
negative regulation of cell death GO:0060548 81 0.019
ovarian follicle cell migration GO:0007297 121 0.019
Fly
regulation of vesicle mediated transport GO:0060627 59 0.019
organophosphate biosynthetic process GO:0090407 46 0.019
cellular response to endogenous stimulus GO:0071495 80 0.019
positive regulation of developmental process GO:0051094 143 0.019
regulation of immune effector process GO:0002697 52 0.019
phosphatidylinositol mediated signaling GO:0048015 4 0.019
response to biotic stimulus GO:0009607 294 0.019
Fly
skin development GO:0043588 65 0.019
Fly
single organism cellular localization GO:1902580 180 0.019
determination of adult lifespan GO:0008340 137 0.018
Fly
response to metal ion GO:0010038 23 0.018
postreplication repair GO:0006301 2 0.018
positive regulation of neurotransmitter secretion GO:0001956 2 0.018
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.018
positive regulation of exocytosis GO:0045921 4 0.018
regulation of reproductive process GO:2000241 54 0.018
lipid localization GO:0010876 54 0.018
Fly
cellular response to lipopolysaccharide GO:0071222 3 0.018
positive regulation of secretion by cell GO:1903532 20 0.018
organic substance catabolic process GO:1901575 308 0.018
secondary metabolic process GO:0019748 75 0.018
cellular response to mechanical stimulus GO:0071260 2 0.018
regulation of nucleotide catabolic process GO:0030811 48 0.018
connective tissue development GO:0061448 3 0.018
positive regulation of signal transduction GO:0009967 223 0.017
synaptic vesicle transport GO:0048489 50 0.017
regulation of neuron projection development GO:0010975 69 0.017
regulation of actin filament based process GO:0032970 42 0.017
peptide metabolic process GO:0006518 80 0.017
cell cycle arrest GO:0007050 4 0.017
potassium ion transmembrane transport GO:0071805 18 0.017
gtp metabolic process GO:0046039 72 0.017
nucleoside triphosphate catabolic process GO:0009143 108 0.017
histone modification GO:0016570 106 0.017
regulation of response to external stimulus GO:0032101 115 0.017
regulation of sequestering of calcium ion GO:0051282 3 0.017
regulation of ion transmembrane transport GO:0034765 27 0.017
developmental programmed cell death GO:0010623 138 0.017
cell migration GO:0016477 238 0.017
Fly
regulation of synapse structure and activity GO:0050803 128 0.017
Zebrafish
regulation of tube size GO:0035150 46 0.016
Fly
regulation of dendrite morphogenesis GO:0048814 28 0.016
carboxylic acid transport GO:0046942 18 0.016
ethanolamine containing compound metabolic process GO:0042439 4 0.016
cellular response to hexose stimulus GO:0071331 1 0.016
cytokinesis GO:0000910 90 0.016
cardiovascular system development GO:0072358 82 0.016
Fly
visual learning GO:0008542 4 0.016
regulation of cell cycle GO:0051726 291 0.016
positive regulation of apoptotic process GO:0043065 47 0.016
regulation of protein localization GO:0032880 76 0.016
segmentation GO:0035282 207 0.016
regulation of transmembrane transporter activity GO:0022898 6 0.016
regulation of immune response GO:0050776 118 0.016
macromolecule catabolic process GO:0009057 161 0.016
spinal cord development GO:0021510 1 0.016
regulation of response to biotic stimulus GO:0002831 63 0.016
cellular response to biotic stimulus GO:0071216 4 0.016
biological adhesion GO:0022610 138 0.015
Human Fly
protein transport GO:0015031 155 0.015
glycosyl compound catabolic process GO:1901658 112 0.015
cytoskeleton dependent cytokinesis GO:0061640 81 0.015

Ace disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.111
cardiovascular system disease DOID:1287 0 0.068
nervous system disease DOID:863 0 0.047
cancer DOID:162 0 0.033
disease of cellular proliferation DOID:14566 0 0.033
disease of metabolism DOID:0014667 0 0.025
acquired metabolic disease DOID:0060158 0 0.025
organ system cancer DOID:0050686 0 0.025
carbohydrate metabolism disease DOID:0050013 0 0.023
glucose metabolism disease DOID:4194 0 0.023
heart conduction disease DOID:10273 0 0.023
diabetes mellitus DOID:9351 0 0.021
musculoskeletal system disease DOID:17 0 0.021