Drosophila melanogaster

201 known processes

S6kII (Dmel_CG17596)

RPS6-protein kinase-II

(Aliases: Rsk,RSK,rsk,dRSK,CG17596,Dmel\CG17596,ign,S6KII)

S6kII biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
learning or memory GO:0007611 141 1.000
photoreceptor cell differentiation GO:0046530 170 0.997
compound eye morphogenesis GO:0001745 249 0.987
eye photoreceptor cell differentiation GO:0001754 145 0.985
neurological system process GO:0050877 358 0.977
learning GO:0007612 75 0.965
compound eye photoreceptor cell differentiation GO:0001751 140 0.959
long term memory GO:0007616 62 0.939
imaginal disc derived appendage morphogenesis GO:0035114 395 0.938
imaginal disc derived appendage development GO:0048737 399 0.932
compound eye development GO:0048749 307 0.921
eye development GO:0001654 323 0.919
eye morphogenesis GO:0048592 260 0.914
regulation of cellular component biogenesis GO:0044087 201 0.885
memory GO:0007613 94 0.878
vesicle localization GO:0051648 55 0.874
compound eye photoreceptor development GO:0042051 78 0.870
eye photoreceptor cell development GO:0042462 81 0.867
regulation of multicellular organismal development GO:2000026 414 0.867
cognition GO:0050890 141 0.867
synapse organization GO:0050808 196 0.866
establishment or maintenance of cell polarity GO:0007163 167 0.840
intracellular signal transduction GO:0035556 300 0.814
imaginal disc derived wing morphogenesis GO:0007476 337 0.803
regulation of photoreceptor cell differentiation GO:0046532 34 0.788
regulation of synapse structure and activity GO:0050803 128 0.768
single organism behavior GO:0044708 391 0.765
wing disc morphogenesis GO:0007472 344 0.704
establishment of localization in cell GO:0051649 402 0.703
brain development GO:0007420 120 0.669
sensory organ morphogenesis GO:0090596 260 0.643
positive regulation of cellular biosynthetic process GO:0031328 316 0.625
Human Fly
regulation of response to external stimulus GO:0032101 115 0.593
Fly
photoreceptor cell development GO:0042461 96 0.593
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.589
regulation of nervous system development GO:0051960 248 0.569
regulation of cell differentiation GO:0045595 302 0.554
rna processing GO:0006396 147 0.546
positive regulation of biosynthetic process GO:0009891 316 0.533
Human Fly
negative regulation of signal transduction GO:0009968 206 0.515
negative regulation of erbb signaling pathway GO:1901185 29 0.502
appendage development GO:0048736 401 0.481
muscle cell differentiation GO:0042692 103 0.470
Fly
regulation of erbb signaling pathway GO:1901184 42 0.469
epidermal growth factor receptor signaling pathway GO:0007173 58 0.463
muscle structure development GO:0061061 224 0.446
Fly
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.444
regulation of response to stress GO:0080134 200 0.423
Mouse Fly
regulation of catalytic activity GO:0050790 185 0.422
Human
regulation of r7 cell differentiation GO:0045676 15 0.409
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.397
intracellular transport GO:0046907 228 0.395
cell adhesion GO:0007155 136 0.394
regulation of cell development GO:0060284 215 0.393
muscle organ development GO:0007517 127 0.391
nuclear division GO:0000280 332 0.390
Mouse Fly
positive regulation of response to stimulus GO:0048584 323 0.386
Mouse Fly
r7 cell differentiation GO:0045466 43 0.382
negative regulation of multicellular organismal process GO:0051241 142 0.378
compound eye photoreceptor fate commitment GO:0001752 36 0.374
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.363
regulation of organ morphogenesis GO:2000027 78 0.358
regulation of protein metabolic process GO:0051246 256 0.352
Human Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.341
Human Mouse Fly
erbb signaling pathway GO:0038127 58 0.337
neuromuscular junction development GO:0007528 149 0.335
synaptic transmission GO:0007268 288 0.335
eye photoreceptor cell fate commitment GO:0042706 37 0.326
ommatidial rotation GO:0016318 20 0.311
negative regulation of response to stimulus GO:0048585 258 0.300
synapse assembly GO:0007416 143 0.296
Fly
establishment of ommatidial planar polarity GO:0042067 49 0.294
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.290
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.283
associative learning GO:0008306 65 0.282
appendage morphogenesis GO:0035107 397 0.279
gene silencing GO:0016458 138 0.275
Fly
regulation of synapse organization GO:0050807 110 0.270
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.268
Human
negative regulation of signaling GO:0023057 219 0.258
negative regulation of cell communication GO:0010648 223 0.255
eggshell formation GO:0030703 105 0.248
morphogenesis of an epithelium GO:0002009 276 0.247
protein complex biogenesis GO:0070271 201 0.242
axonogenesis GO:0007409 290 0.242
Fly
negative regulation of rna biosynthetic process GO:1902679 240 0.239
Fly
muscle fiber development GO:0048747 12 0.236
positive regulation of protein metabolic process GO:0051247 128 0.229
nucleocytoplasmic transport GO:0006913 72 0.224
post embryonic appendage morphogenesis GO:0035120 385 0.221
regulation of intracellular signal transduction GO:1902531 236 0.220
establishment of vesicle localization GO:0051650 51 0.219
epithelial tube morphogenesis GO:0060562 88 0.219
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.216
Human Fly
cell type specific apoptotic process GO:0097285 38 0.211
Mouse
establishment of planar polarity GO:0001736 87 0.211
positive regulation of signaling GO:0023056 243 0.211
regulation of molecular function GO:0065009 217 0.206
Human
vesicle mediated transport GO:0016192 381 0.202
Fly
signal transduction by phosphorylation GO:0023014 107 0.200
Mouse
regulation of apoptotic process GO:0042981 130 0.200
Human
neuroblast proliferation GO:0007405 74 0.198
eggshell chorion assembly GO:0007306 66 0.196
locomotory behavior GO:0007626 176 0.193
transcription from rna polymerase ii promoter GO:0006366 368 0.192
Human
positive regulation of transcription dna templated GO:0045893 266 0.190
Human Fly
negative regulation of developmental growth GO:0048640 64 0.187
protein complex assembly GO:0006461 200 0.187
positive regulation of signal transduction GO:0009967 223 0.187
adult behavior GO:0030534 137 0.186
cell proliferation GO:0008283 299 0.185
Human
positive regulation of macromolecule metabolic process GO:0010604 405 0.183
Human Mouse Fly
enzyme linked receptor protein signaling pathway GO:0007167 179 0.181
terminal button organization GO:0072553 19 0.176
compound eye cone cell differentiation GO:0042675 13 0.173
protein localization GO:0008104 284 0.173
mapk cascade GO:0000165 107 0.170
Mouse
synaptic vesicle localization GO:0097479 53 0.160
regulation of programmed cell death GO:0043067 152 0.158
Human
regionalization GO:0003002 416 0.158
regulation of notch signaling pathway GO:0008593 100 0.158
regulation of phosphorylation GO:0042325 147 0.157
Mouse
regulation of cellular response to stress GO:0080135 89 0.156
Fly
dna integrity checkpoint GO:0031570 81 0.154
establishment of organelle localization GO:0051656 122 0.153
positive regulation of cellular protein metabolic process GO:0032270 118 0.148
male gamete generation GO:0048232 201 0.148
proteolysis GO:0006508 192 0.146
Human
regulation of cell morphogenesis GO:0022604 163 0.146
olfactory learning GO:0008355 56 0.144
regulation of transport GO:0051049 181 0.144
regulation of cellular component size GO:0032535 98 0.143
Fly
positive regulation of nervous system development GO:0051962 69 0.143
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.142
Human
regulation of phosphate metabolic process GO:0019220 210 0.141
Mouse
regulation of cellular protein metabolic process GO:0032268 243 0.140
Human
organelle localization GO:0051640 148 0.137
cellular protein modification process GO:0006464 438 0.134
cellular response to dna damage stimulus GO:0006974 223 0.132
Human Fly
asymmetric protein localization GO:0008105 33 0.131
adherens junction organization GO:0034332 27 0.130
negative regulation of gene expression GO:0010629 387 0.129
Human Fly
tube development GO:0035295 244 0.128
Zebrafish
epithelium migration GO:0090132 148 0.128
immune system process GO:0002376 347 0.126
Mouse
hemopoiesis GO:0030097 46 0.122
mitotic g2 m transition checkpoint GO:0044818 70 0.121
biological adhesion GO:0022610 138 0.120
phosphorylation GO:0016310 294 0.120
mitotic dna damage checkpoint GO:0044773 74 0.120
mitotic dna integrity checkpoint GO:0044774 75 0.118
protein phosphorylation GO:0006468 169 0.118
developmental growth GO:0048589 280 0.116
Fly
notch signaling pathway GO:0007219 120 0.114
negative regulation of developmental process GO:0051093 201 0.114
positive regulation of r7 cell differentiation GO:0045678 7 0.114
endocytosis GO:0006897 310 0.109
Fly
small gtpase mediated signal transduction GO:0007264 88 0.107
single organism intracellular transport GO:1902582 207 0.106
programmed cell death GO:0012501 257 0.105
Human Mouse
response to wounding GO:0009611 94 0.104
negative regulation of biosynthetic process GO:0009890 277 0.104
Fly
establishment of synaptic vesicle localization GO:0097480 50 0.103
peptidyl amino acid modification GO:0018193 105 0.103
Mouse Fly
oocyte microtubule cytoskeleton organization GO:0016325 35 0.101
regulation of growth GO:0040008 233 0.100
dna damage checkpoint GO:0000077 78 0.099
morphogenesis of a polarized epithelium GO:0001738 93 0.099
tissue migration GO:0090130 155 0.099
telencephalon development GO:0021537 2 0.096
positive regulation of cell communication GO:0010647 250 0.094
Fly
mitotic g2 dna damage checkpoint GO:0007095 69 0.093
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.092
Fly
chorion containing eggshell formation GO:0007304 105 0.091
negative regulation of cellular biosynthetic process GO:0031327 277 0.091
Fly
circadian rhythm GO:0007623 105 0.089
short term memory GO:0007614 19 0.089
regulation of developmental growth GO:0048638 174 0.088
regulation of phosphorus metabolic process GO:0051174 210 0.086
Mouse
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.085
establishment of tissue polarity GO:0007164 87 0.084
regulation of transferase activity GO:0051338 58 0.083
homeostatic process GO:0042592 199 0.083
Fly
regulation of vesicle mediated transport GO:0060627 59 0.083
regulation of mapk cascade GO:0043408 92 0.083
Mouse
macromolecular complex assembly GO:0065003 256 0.083
positive regulation of molecular function GO:0044093 136 0.083
regulation of synapse assembly GO:0051963 94 0.082
notch receptor processing GO:0007220 13 0.082
jnk cascade GO:0007254 50 0.081
negative regulation of nucleic acid templated transcription GO:1903507 240 0.079
Fly
positive regulation of cellular component biogenesis GO:0044089 80 0.076
central nervous system development GO:0007417 201 0.075
single organism cell adhesion GO:0098602 47 0.074
protein modification process GO:0036211 438 0.073
aromatic compound catabolic process GO:0019439 166 0.071
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.071
Fly
ovarian follicle cell development GO:0030707 248 0.071
regulation of anatomical structure morphogenesis GO:0022603 242 0.070
behavioral response to ethanol GO:0048149 49 0.069
regulation of map kinase activity GO:0043405 17 0.069
cytoskeleton dependent intracellular transport GO:0030705 44 0.067
regulation of immune system process GO:0002682 176 0.067
Mouse
negative regulation of transcription dna templated GO:0045892 237 0.067
Fly
regulation of neurogenesis GO:0050767 158 0.066
response to oxidative stress GO:0006979 86 0.066
regulation of protein complex assembly GO:0043254 42 0.065
negative regulation of intracellular signal transduction GO:1902532 57 0.065
response to growth factor GO:0070848 31 0.065
positive regulation of intracellular signal transduction GO:1902533 116 0.065
regulation of cell proliferation GO:0042127 163 0.064
Human
stem cell division GO:0017145 69 0.063
tube morphogenesis GO:0035239 191 0.062
circadian behavior GO:0048512 76 0.061
single organismal cell cell adhesion GO:0016337 45 0.060
regulation of proteolysis GO:0030162 87 0.059
Human
positive regulation of mapk cascade GO:0043410 63 0.059
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.059
regulation of small gtpase mediated signal transduction GO:0051056 93 0.058
ras protein signal transduction GO:0007265 88 0.058
neuron projection guidance GO:0097485 241 0.058
Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.058
organic substance catabolic process GO:1901575 308 0.056
negative regulation of catalytic activity GO:0043086 42 0.056
Human
regulation of catabolic process GO:0009894 170 0.056
Fly
photoreceptor cell fate commitment GO:0046552 41 0.056
mrna processing GO:0006397 104 0.055
embryo development ending in birth or egg hatching GO:0009792 152 0.055
stress activated protein kinase signaling cascade GO:0031098 55 0.055
purine ribonucleotide metabolic process GO:0009150 145 0.055
cellular protein localization GO:0034613 160 0.054
actin filament organization GO:0007015 126 0.054
Fly
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.054
macromolecule catabolic process GO:0009057 161 0.054
regulation of wnt signaling pathway GO:0030111 68 0.053
positive regulation of cell differentiation GO:0045597 64 0.053
tissue morphogenesis GO:0048729 297 0.053
positive regulation of developmental process GO:0051094 143 0.053
regulation of endocytosis GO:0030100 37 0.053
peripheral nervous system development GO:0007422 52 0.053
axon development GO:0061564 297 0.052
Fly
negative regulation of nervous system development GO:0051961 92 0.051
mrna metabolic process GO:0016071 124 0.050
regulation of canonical wnt signaling pathway GO:0060828 15 0.050
positive regulation of multicellular organismal process GO:0051240 143 0.050
nuclear transport GO:0051169 72 0.049
dorsal appendage formation GO:0046843 47 0.049
epithelial cell migration GO:0010631 148 0.049
stress activated mapk cascade GO:0051403 52 0.049
nucleobase containing compound catabolic process GO:0034655 165 0.048
apoptotic process GO:0006915 159 0.048
Human Mouse
negative regulation of cell differentiation GO:0045596 143 0.046
hematopoietic or lymphoid organ development GO:0048534 57 0.046
actin cytoskeleton organization GO:0030036 206 0.046
Fly
negative regulation of cell death GO:0060548 81 0.045
Human
olfactory behavior GO:0042048 97 0.045
erk1 and erk2 cascade GO:0070371 39 0.045
Mouse
muscle tissue development GO:0060537 30 0.044
methylation GO:0032259 47 0.044
cell motility GO:0048870 251 0.043
taxis GO:0042330 304 0.043
Fly
nucleoside triphosphate catabolic process GO:0009143 108 0.043
immune response activating signal transduction GO:0002757 2 0.043
Mouse
germ line stem cell maintenance GO:0030718 50 0.042
positive regulation of cellular component organization GO:0051130 156 0.042
regulation of cell fate commitment GO:0010453 29 0.041
striated muscle tissue development GO:0014706 27 0.041
covalent chromatin modification GO:0016569 106 0.041
Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.040
Human Fly
microtubule based transport GO:0010970 42 0.040
skin development GO:0043588 65 0.040
Zebrafish
fertilization GO:0009566 26 0.040
positive regulation of cell development GO:0010720 61 0.040
germarium derived female germ line cyst formation GO:0030727 42 0.039
meiotic cell cycle GO:0051321 171 0.039
Mouse Fly
organelle fission GO:0048285 340 0.039
Mouse Fly
regulation of actin filament length GO:0030832 27 0.039
regulation of protein modification process GO:0031399 112 0.039
kidney development GO:0001822 3 0.039
negative regulation of ras protein signal transduction GO:0046580 13 0.039
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.039
negative regulation of notch signaling pathway GO:0045746 41 0.039
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.039
head development GO:0060322 135 0.038
death GO:0016265 284 0.038
Human Mouse
rhabdomere development GO:0042052 38 0.038
regulation of actin cytoskeleton organization GO:0032956 42 0.038
negative regulation of cell development GO:0010721 62 0.037
regulation of neuroblast proliferation GO:1902692 34 0.037
actin polymerization or depolymerization GO:0008154 31 0.037
cell aging GO:0007569 2 0.037
response to endogenous stimulus GO:0009719 119 0.036
germarium derived egg chamber formation GO:0007293 101 0.036
cellular nitrogen compound catabolic process GO:0044270 165 0.036
negative regulation of cell cycle phase transition GO:1901988 103 0.036
adherens junction assembly GO:0034333 11 0.036
chemosensory behavior GO:0007635 106 0.036
negative regulation of cell cycle GO:0045786 116 0.036
Human Mouse
negative regulation of rna metabolic process GO:0051253 251 0.036
Fly
striated muscle cell differentiation GO:0051146 90 0.036
Fly
dendrite development GO:0016358 204 0.035
Fly
renal tubule development GO:0061326 64 0.035
regulation of localization GO:0032879 275 0.035
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.035
multicellular organismal homeostasis GO:0048871 41 0.035
regulation of cell shape GO:0008360 113 0.034
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.034
Fly
positive regulation of phosphorylation GO:0042327 87 0.034
response to starvation GO:0042594 97 0.034
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.034
Human Fly
negative regulation of growth GO:0045926 84 0.034
regulation of neural precursor cell proliferation GO:2000177 35 0.034
positive regulation of phosphate metabolic process GO:0045937 139 0.034
protein modification by small protein conjugation or removal GO:0070647 106 0.034
guanosine containing compound metabolic process GO:1901068 74 0.033
cytoplasmic transport GO:0016482 130 0.033
organonitrogen compound metabolic process GO:1901564 318 0.033
gtp catabolic process GO:0006184 72 0.032
renal filtration GO:0097205 7 0.032
cellular response to endogenous stimulus GO:0071495 80 0.032
cell activation GO:0001775 9 0.032
Human
wnt signaling pathway GO:0016055 98 0.031
cellular response to growth factor stimulus GO:0071363 30 0.031
defense response GO:0006952 300 0.031
Mouse
growth GO:0040007 359 0.031
Fly
protein ubiquitination GO:0016567 70 0.030
purine containing compound catabolic process GO:0072523 112 0.030
regulation of cell cycle GO:0051726 291 0.030
Human Mouse
cellular macromolecule localization GO:0070727 220 0.030
neuron apoptotic process GO:0051402 17 0.030
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.030
Mouse
chemotaxis GO:0006935 249 0.030
Fly
organophosphate metabolic process GO:0019637 195 0.030
meiotic nuclear division GO:0007126 151 0.029
Mouse Fly
regulation of defense response GO:0031347 102 0.029
Mouse
regulation of protein catabolic process GO:0042176 55 0.029
stem cell fate commitment GO:0048865 25 0.029
regulation of apoptotic signaling pathway GO:2001233 10 0.028
wound healing GO:0042060 75 0.028
protein modification by small protein conjugation GO:0032446 79 0.028
g protein coupled receptor signaling pathway GO:0007186 136 0.028
cellular macromolecular complex assembly GO:0034622 153 0.028
regulation of jnk cascade GO:0046328 40 0.028
cellular macromolecule catabolic process GO:0044265 136 0.028
response to nutrient levels GO:0031667 114 0.028
Fly
regulation of stress activated mapk cascade GO:0032872 41 0.027
synaptic vesicle transport GO:0048489 50 0.027
response to ionizing radiation GO:0010212 32 0.027
positive regulation of gene expression GO:0010628 290 0.027
Human Mouse Fly
developmental growth involved in morphogenesis GO:0060560 65 0.027
exocrine system development GO:0035272 162 0.027
embryonic morphogenesis GO:0048598 206 0.027
regulation of embryonic development GO:0045995 68 0.026
Mouse
carbohydrate derivative catabolic process GO:1901136 118 0.026
posttranscriptional gene silencing GO:0016441 46 0.025
posttranscriptional gene silencing by rna GO:0035194 45 0.025
protein catabolic process GO:0030163 101 0.025
positive regulation of neurogenesis GO:0050769 41 0.025
regulation of cell death GO:0010941 173 0.025
Human
response to external biotic stimulus GO:0043207 293 0.025
Mouse
histone modification GO:0016570 106 0.025
Fly
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.025
regulation of circadian rhythm GO:0042752 49 0.025
immune system development GO:0002520 57 0.025
positive regulation of rna metabolic process GO:0051254 271 0.025
Human Fly
regulation of cellular amine metabolic process GO:0033238 3 0.025
regulation of response to wounding GO:1903034 19 0.024
positive regulation of endocytosis GO:0045807 22 0.024
regulation of protein kinase activity GO:0045859 51 0.024
negative regulation of programmed cell death GO:0043069 72 0.024
Human
cell cell junction organization GO:0045216 55 0.024
protein heterooligomerization GO:0051291 4 0.023
digestive system development GO:0055123 149 0.023
Zebrafish
urogenital system development GO:0001655 72 0.023
multicellular organismal aging GO:0010259 140 0.023
regulation of cellular catabolic process GO:0031329 157 0.023
Fly
negative regulation of protein metabolic process GO:0051248 85 0.023
Human
axon cargo transport GO:0008088 29 0.023
regulation of autophagy GO:0010506 62 0.023
Fly
actin filament bundle organization GO:0061572 28 0.023
regulation of cell size GO:0008361 63 0.023
Fly
positive regulation of wnt signaling pathway GO:0030177 25 0.023
compound eye retinal cell programmed cell death GO:0046667 23 0.023
cellular response to insulin stimulus GO:0032869 28 0.023
actin filament based process GO:0030029 220 0.022
Fly
morphogenesis of a branching epithelium GO:0061138 45 0.022
gliogenesis GO:0042063 80 0.022
response to radiation GO:0009314 155 0.022
pigment cell differentiation GO:0050931 3 0.022
multi organism behavior GO:0051705 175 0.022
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.022
macromolecule methylation GO:0043414 45 0.022
cellular catabolic process GO:0044248 372 0.022
Fly
cell junction organization GO:0034330 57 0.022
positive regulation of synapse assembly GO:0051965 29 0.022
positive regulation of catabolic process GO:0009896 105 0.022
Fly
catabolic process GO:0009056 409 0.022
Fly
heterocycle catabolic process GO:0046700 166 0.022
inositol lipid mediated signaling GO:0048017 4 0.022
myotube cell development GO:0014904 3 0.022
canonical wnt signaling pathway GO:0060070 21 0.022
purine ribonucleoside catabolic process GO:0046130 112 0.022
asymmetric stem cell division GO:0098722 49 0.021
regulation of actin polymerization or depolymerization GO:0008064 27 0.021
chromatin modification GO:0016568 147 0.021
Fly
regulation of execution phase of apoptosis GO:1900117 5 0.021
regulation of epithelial cell proliferation GO:0050678 4 0.021
posttranscriptional regulation of gene expression GO:0010608 145 0.021
regulation of receptor mediated endocytosis GO:0048259 9 0.021
purine nucleotide catabolic process GO:0006195 109 0.021
negative regulation of wnt signaling pathway GO:0030178 28 0.021
negative regulation of phosphorus metabolic process GO:0010563 45 0.021
Mouse
immune response GO:0006955 246 0.021
Mouse
regulation of synaptic vesicle endocytosis GO:1900242 7 0.020
determination of adult lifespan GO:0008340 137 0.020
regulation of ras protein signal transduction GO:0046578 93 0.020
morphogenesis of a branching structure GO:0001763 45 0.020
positive regulation of immune system process GO:0002684 68 0.020
Mouse
negative regulation of phosphate metabolic process GO:0045936 45 0.020
Mouse
negative regulation of mitotic cell cycle GO:0045930 109 0.020
columnar cuboidal epithelial cell development GO:0002066 249 0.020
larval development GO:0002164 104 0.020
germ line cyst formation GO:0048134 44 0.020
positive regulation of cell motility GO:2000147 3 0.020
regulation of translation GO:0006417 56 0.020
mitotic cell cycle checkpoint GO:0007093 88 0.020
protein localization to nucleus GO:0034504 55 0.020
morphogenesis of embryonic epithelium GO:0016331 94 0.020
positive regulation of transferase activity GO:0051347 26 0.019
cell projection assembly GO:0030031 94 0.019
organic cyclic compound catabolic process GO:1901361 168 0.019
cellular response to nutrient levels GO:0031669 62 0.019
Fly
nucleobase containing small molecule metabolic process GO:0055086 174 0.019
g2 dna damage checkpoint GO:0031572 69 0.019
organ growth GO:0035265 56 0.019
torc1 signaling GO:0038202 12 0.018
purine containing compound metabolic process GO:0072521 155 0.018
regulation of epithelial cell differentiation GO:0030856 4 0.018
epidermis development GO:0008544 65 0.018
intrinsic apoptotic signaling pathway GO:0097193 16 0.018
gland development GO:0048732 191 0.018
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.018
purine nucleoside catabolic process GO:0006152 112 0.018
axon guidance GO:0007411 233 0.018
Fly
positive regulation of kinase activity GO:0033674 25 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
positive regulation of jun kinase activity GO:0043507 4 0.018
spermatogenesis GO:0007283 200 0.018
response to hormone GO:0009725 45 0.018
cellular pigmentation GO:0033059 12 0.018
rhythmic behavior GO:0007622 76 0.017
negative regulation of mapk cascade GO:0043409 23 0.017
Mouse
nucleoside triphosphate metabolic process GO:0009141 120 0.017
lateral inhibition GO:0046331 206 0.017
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.017
regulation of bmp signaling pathway GO:0030510 23 0.017
regulation of cellular localization GO:0060341 136 0.017
positive regulation of neuron apoptotic process GO:0043525 1 0.017
regulation of organ growth GO:0046620 42 0.017
muscle system process GO:0003012 21 0.017
chaeta development GO:0022416 97 0.017
cystoblast division GO:0007282 10 0.017
extrinsic apoptotic signaling pathway GO:0097191 1 0.017
nucleotide catabolic process GO:0009166 109 0.017
negative regulation of cellular protein metabolic process GO:0032269 85 0.017
Human
endomembrane system organization GO:0010256 119 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.017
Fly
positive regulation of apoptotic signaling pathway GO:2001235 4 0.017
epithelial cell differentiation GO:0030855 322 0.017
regulation of muscle contraction GO:0006937 5 0.017
macromolecule deacylation GO:0098732 11 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.016
regulation of behavior GO:0050795 75 0.016
regulation of synaptic transmission GO:0050804 69 0.016
regulation of mrna metabolic process GO:1903311 72 0.016
dorsal ventral pattern formation GO:0009953 133 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
regulation of cell substrate adhesion GO:0010810 2 0.016
nucleoside metabolic process GO:0009116 127 0.016
cellular response to oxidative stress GO:0034599 28 0.016
actin filament polymerization GO:0030041 27 0.016
compound eye pigmentation GO:0048072 17 0.016
response to abiotic stimulus GO:0009628 341 0.016
regulation of cell adhesion GO:0030155 27 0.016
cell cycle checkpoint GO:0000075 95 0.016
digestive tract morphogenesis GO:0048546 127 0.016
regulation of neuron differentiation GO:0045664 103 0.016
circulatory system development GO:0072359 82 0.015
Mouse
negative regulation of apoptotic process GO:0043066 63 0.015
Human
negative regulation of synapse assembly GO:0051964 39 0.015
forebrain development GO:0030900 2 0.015
response to lipopolysaccharide GO:0032496 4 0.015
Mouse
negative regulation of neurogenesis GO:0050768 53 0.015
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.015
neuron death GO:0070997 27 0.015
regulation of cell cycle phase transition GO:1901987 130 0.015

S6kII disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
cardiovascular system disease DOID:1287 0 0.017