Drosophila melanogaster

13 known processes

CG5428 (Dmel_CG5428)

CG5428 gene product from transcript CG5428-RB

(Aliases: Dmel\CG5428)

CG5428 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
small molecule metabolic process GO:0044281 305 0.068
Human
organonitrogen compound metabolic process GO:1901564 318 0.050
Human Rat
endocytosis GO:0006897 310 0.039
sterol homeostasis GO:0055092 4 0.038
cell cell signaling involved in cell fate commitment GO:0045168 210 0.038
carboxylic acid metabolic process GO:0019752 92 0.038
Human
lateral inhibition GO:0046331 206 0.038
imaginal disc derived appendage development GO:0048737 399 0.034
organic acid metabolic process GO:0006082 103 0.033
Human
phagocytosis GO:0006909 215 0.033
catabolic process GO:0009056 409 0.033
single organism biosynthetic process GO:0044711 206 0.033
vesicle mediated transport GO:0016192 381 0.032
response to biotic stimulus GO:0009607 294 0.032
Fly
imaginal disc derived appendage morphogenesis GO:0035114 395 0.031
organic substance transport GO:0071702 257 0.031
organelle fission GO:0048285 340 0.031
oxoacid metabolic process GO:0043436 103 0.031
Human
body morphogenesis GO:0010171 2 0.031
defense response GO:0006952 300 0.030
Fly
response to bacterium GO:0009617 198 0.030
Fly
response to abiotic stimulus GO:0009628 341 0.030
response to external biotic stimulus GO:0043207 293 0.030
Fly
post embryonic appendage morphogenesis GO:0035120 385 0.030
appendage development GO:0048736 401 0.029
response to other organism GO:0051707 293 0.029
Fly
imaginal disc derived wing morphogenesis GO:0007476 337 0.029
organic substance catabolic process GO:1901575 308 0.029
cellular catabolic process GO:0044248 372 0.029
homeostatic process GO:0042592 199 0.029
wing disc morphogenesis GO:0007472 344 0.028
taxis GO:0042330 304 0.028
positive regulation of cell communication GO:0010647 250 0.027
appendage morphogenesis GO:0035107 397 0.027
epithelial cell differentiation GO:0030855 322 0.027
Human
nuclear division GO:0000280 332 0.027
regionalization GO:0003002 416 0.026
protein modification process GO:0036211 438 0.026
neurological system process GO:0050877 358 0.026
cellular amino acid metabolic process GO:0006520 61 0.025
Human
response to lipopolysaccharide GO:0032496 4 0.025
kidney development GO:0001822 3 0.025
compound eye development GO:0048749 307 0.025
lipid metabolic process GO:0006629 121 0.025
Human Rat
cellular protein modification process GO:0006464 438 0.025
response to organic substance GO:0010033 284 0.025
Rat
single organism behavior GO:0044708 391 0.025
ethanolamine containing compound metabolic process GO:0042439 4 0.025
anion homeostasis GO:0055081 3 0.024
open tracheal system development GO:0007424 204 0.024
response to organophosphorus GO:0046683 2 0.024
detection of stimulus GO:0051606 156 0.024
carbohydrate derivative metabolic process GO:1901135 217 0.024
cellular lipid metabolic process GO:0044255 83 0.023
immune system process GO:0002376 347 0.023
establishment of localization in cell GO:0051649 402 0.023
defense response to other organism GO:0098542 225 0.023
Fly
positive regulation of signaling GO:0023056 243 0.022
cell death GO:0008219 279 0.022
steroid catabolic process GO:0006706 1 0.022
regulation of cell cycle GO:0051726 291 0.022
salivary gland morphogenesis GO:0007435 145 0.022
death GO:0016265 284 0.022
cellular amine metabolic process GO:0044106 12 0.022
macromolecular complex assembly GO:0065003 256 0.022
exocrine system development GO:0035272 162 0.022
positive regulation of response to stimulus GO:0048584 323 0.022
negative regulation of gene expression GO:0010629 387 0.022
eye development GO:0001654 323 0.022
cellular ketone metabolic process GO:0042180 24 0.021
amine metabolic process GO:0009308 12 0.021
positive regulation of signal transduction GO:0009967 223 0.021
regulation of localization GO:0032879 275 0.021
programmed cell death GO:0012501 257 0.021
regulation of molecular function GO:0065009 217 0.020
immune response activating signal transduction GO:0002757 2 0.020
single organism catabolic process GO:0044712 228 0.020
regulation of multicellular organismal development GO:2000026 414 0.020
transcription from rna polymerase ii promoter GO:0006366 368 0.020
hormone catabolic process GO:0042447 3 0.020
defense response to bacterium GO:0042742 178 0.020
Fly
intracellular signal transduction GO:0035556 300 0.020
cholesterol homeostasis GO:0042632 3 0.020
developmental programmed cell death GO:0010623 138 0.020
sensory organ morphogenesis GO:0090596 260 0.020
forebrain development GO:0030900 2 0.020
gland morphogenesis GO:0022612 145 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
immune response regulating signaling pathway GO:0002764 2 0.020
positive regulation of macromolecule metabolic process GO:0010604 405 0.019
response to glucose GO:0009749 2 0.019
androgen metabolic process GO:0008209 1 0.019
chemotaxis GO:0006935 249 0.019
immune response GO:0006955 246 0.019
negative regulation of cellular metabolic process GO:0031324 382 0.019
chromosome organization GO:0051276 360 0.019
vitamin biosynthetic process GO:0009110 1 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.019
compound eye morphogenesis GO:0001745 249 0.018
histolysis GO:0007559 102 0.018
single organism intracellular transport GO:1902582 207 0.018
epithelial cell development GO:0002064 274 0.018
chemical homeostasis GO:0048878 92 0.018
morphogenesis of an epithelium GO:0002009 276 0.018
regulation of response to stress GO:0080134 200 0.018
multi organism behavior GO:0051705 175 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
proteolysis GO:0006508 192 0.018
cell proliferation GO:0008283 299 0.018
developmental growth GO:0048589 280 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.018
gland development GO:0048732 191 0.018
spindle organization GO:0007051 253 0.018
camera type eye development GO:0043010 4 0.018
adult behavior GO:0030534 137 0.017
very long chain fatty acid metabolic process GO:0000038 4 0.017
sensory perception GO:0007600 196 0.017
neutral lipid biosynthetic process GO:0046460 2 0.017
positive regulation of lipid storage GO:0010884 4 0.017
axonogenesis GO:0007409 290 0.017
organonitrogen compound catabolic process GO:1901565 128 0.017
tissue death GO:0016271 102 0.017
nucleobase containing small molecule metabolic process GO:0055086 174 0.017
positive regulation of cell migration GO:0030335 2 0.017
positive regulation of gene expression GO:0010628 290 0.017
response to radiation GO:0009314 155 0.017
eye morphogenesis GO:0048592 260 0.017
organophosphate metabolic process GO:0019637 195 0.017
connective tissue development GO:0061448 3 0.017
cellular response to lipopolysaccharide GO:0071222 3 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
regulation of mitotic cell cycle GO:0007346 190 0.017
salivary gland development GO:0007431 162 0.017
regulation of immune system process GO:0002682 176 0.016
innate immune response activating signal transduction GO:0002758 2 0.016
organic hydroxy compound metabolic process GO:1901615 83 0.016
Human Rat
activation of innate immune response GO:0002218 4 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
positive regulation of biosynthetic process GO:0009891 316 0.016
pattern recognition receptor signaling pathway GO:0002221 2 0.016
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.016
organelle assembly GO:0070925 198 0.016
chromosome segregation GO:0007059 157 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
meiotic cell cycle process GO:1903046 132 0.016
respiratory system development GO:0060541 213 0.016
cholesterol transport GO:0030301 2 0.016
anatomical structure homeostasis GO:0060249 97 0.016
regulation of catalytic activity GO:0050790 185 0.016
response to monosaccharide GO:0034284 4 0.016
mating GO:0007618 120 0.016
xenobiotic catabolic process GO:0042178 1 0.016
response to hexose GO:0009746 3 0.016
cell migration GO:0016477 238 0.016
localization of cell GO:0051674 257 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
organonitrogen compound biosynthetic process GO:1901566 117 0.016
organic cyclic compound catabolic process GO:1901361 168 0.015
positive regulation of cell motility GO:2000147 3 0.015
intracellular transport GO:0046907 228 0.015
heterocycle catabolic process GO:0046700 166 0.015
polyol biosynthetic process GO:0046173 3 0.015
protein complex biogenesis GO:0070271 201 0.015
macromolecule catabolic process GO:0009057 161 0.015
neuron projection guidance GO:0097485 241 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
innate immune response GO:0045087 144 0.015
mitotic nuclear division GO:0007067 213 0.015
cell recognition GO:0008037 102 0.015
response to light stimulus GO:0009416 124 0.015
axon development GO:0061564 297 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
phosphorylation GO:0016310 294 0.015
pheromone biosynthetic process GO:0042811 3 0.015
protein localization GO:0008104 284 0.015
lipid biosynthetic process GO:0008610 46 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
telencephalon development GO:0021537 2 0.015
cell motility GO:0048870 251 0.015
axon guidance GO:0007411 233 0.015
fat soluble vitamin metabolic process GO:0006775 1 0.015
response to oxygen containing compound GO:1901700 200 0.015
Rat
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.015
purine containing compound metabolic process GO:0072521 155 0.015
axis specification GO:0009798 167 0.015
salivary gland cell autophagic cell death GO:0035071 83 0.015
cellular response to organic substance GO:0071310 132 0.015
Rat
vitamin metabolic process GO:0006766 2 0.015
aromatic compound catabolic process GO:0019439 166 0.015
regulation of immune response GO:0050776 118 0.015
protein complex assembly GO:0006461 200 0.015
autophagic cell death GO:0048102 83 0.014
segmentation GO:0035282 207 0.014
acetate ester metabolic process GO:1900619 2 0.014
regulation of anatomical structure size GO:0090066 163 0.014
long chain fatty acid metabolic process GO:0001676 3 0.014
chitin based cuticle development GO:0040003 49 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
ovarian follicle cell development GO:0030707 248 0.014
cellular macromolecule localization GO:0070727 220 0.014
dorsal ventral pattern formation GO:0009953 133 0.014
tissue morphogenesis GO:0048729 297 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
salivary gland histolysis GO:0035070 88 0.014
spermatogenesis GO:0007283 200 0.014
locomotory behavior GO:0007626 176 0.014
acetylcholine metabolic process GO:0008291 2 0.014
monocarboxylic acid transport GO:0015718 3 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
secondary metabolic process GO:0019748 75 0.014
multi organism reproductive behavior GO:0044705 121 0.014
tube development GO:0035295 244 0.014
maintenance of location GO:0051235 73 0.014
regulation of transport GO:0051049 181 0.014
nucleotide metabolic process GO:0009117 161 0.014
neurotransmitter metabolic process GO:0042133 2 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
ras protein signal transduction GO:0007265 88 0.014
small gtpase mediated signal transduction GO:0007264 88 0.013
l amino acid import GO:0043092 2 0.013
endomembrane system organization GO:0010256 119 0.013
biological adhesion GO:0022610 138 0.013
regulation of innate immune response GO:0045088 71 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
triglyceride biosynthetic process GO:0019432 2 0.013
regulation of sequestering of triglyceride GO:0010889 3 0.013
pigmentation GO:0043473 75 0.013
cellular response to ethanol GO:0071361 4 0.013
meiotic nuclear division GO:0007126 151 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
fat soluble vitamin biosynthetic process GO:0042362 1 0.013
embryonic pattern specification GO:0009880 174 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
cuticle development GO:0042335 86 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
cell division GO:0051301 248 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
detection of chemical stimulus GO:0009593 93 0.013
detection of light stimulus GO:0009583 58 0.013
response to temperature stimulus GO:0009266 106 0.013
positive regulation of molecular function GO:0044093 136 0.013
amine catabolic process GO:0009310 1 0.013
rna processing GO:0006396 147 0.013
cellular modified amino acid metabolic process GO:0006575 45 0.013
Human
ion transport GO:0006811 145 0.013
glycerolipid catabolic process GO:0046503 3 0.013
limb development GO:0060173 1 0.013
protein transport GO:0015031 155 0.013
meiotic cell cycle GO:0051321 171 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
l glutamate import GO:0051938 1 0.012
negative regulation of signal transduction GO:0009968 206 0.012
regulation of cell death GO:0010941 173 0.012
apoptotic process GO:0006915 159 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.012
jak stat cascade GO:0007259 49 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
hormone metabolic process GO:0042445 33 0.012
Human Rat
purine nucleoside metabolic process GO:0042278 127 0.012
hindbrain development GO:0030902 2 0.012
positive regulation of nucleic acid templated transcription GO:1903508 266 0.012
male gamete generation GO:0048232 201 0.012
lipid localization GO:0010876 54 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
regulation of gene expression epigenetic GO:0040029 128 0.012
regulation of nervous system development GO:0051960 248 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
sensory perception of smell GO:0007608 80 0.012
gene silencing GO:0016458 138 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
regulation of catabolic process GO:0009894 170 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
regulation of cell differentiation GO:0045595 302 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
nucleoside metabolic process GO:0009116 127 0.012
cell cycle phase transition GO:0044770 140 0.012
benzene containing compound metabolic process GO:0042537 3 0.012
estrogen metabolic process GO:0008210 1 0.012
Human Rat
positive regulation of rna biosynthetic process GO:1902680 266 0.012
choline metabolic process GO:0019695 1 0.012
tube morphogenesis GO:0035239 191 0.012
neuropeptide signaling pathway GO:0007218 45 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
adult locomotory behavior GO:0008344 76 0.012
neuron recognition GO:0008038 101 0.012
regulation of organelle organization GO:0033043 196 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
regulation of lipid transport GO:0032368 3 0.012
hematopoietic progenitor cell differentiation GO:0002244 1 0.012
small molecule biosynthetic process GO:0044283 37 0.012
phospholipid homeostasis GO:0055091 1 0.012
blastoderm segmentation GO:0007350 159 0.012
regulation of cell cycle process GO:0010564 181 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
neurotransmitter catabolic process GO:0042135 1 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
regulation of programmed cell death GO:0043067 152 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
chaeta development GO:0022416 97 0.012
humoral immune response GO:0006959 117 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
negative regulation of rna biosynthetic process GO:1902679 240 0.012
mesenchymal cell development GO:0014031 1 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
purine containing compound catabolic process GO:0072523 112 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
regulation of cell proliferation GO:0042127 163 0.011
eye photoreceptor cell differentiation GO:0001754 145 0.011
ameboidal type cell migration GO:0001667 151 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
multicellular organismal aging GO:0010259 140 0.011
alditol phosphate metabolic process GO:0052646 2 0.011
toxin metabolic process GO:0009404 2 0.011
establishment of protein localization GO:0045184 163 0.011
central nervous system development GO:0007417 201 0.011
acylglycerol catabolic process GO:0046464 3 0.011
fatty acid elongation GO:0030497 3 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
negative regulation of developmental process GO:0051093 201 0.011
acylglycerol biosynthetic process GO:0046463 2 0.011
organophosphate catabolic process GO:0046434 112 0.011
single organism cellular localization GO:1902580 180 0.011
rna localization GO:0006403 115 0.011
regulation of protein metabolic process GO:0051246 256 0.011
detection of abiotic stimulus GO:0009582 66 0.011
cellular protein localization GO:0034613 160 0.011
nucleoside catabolic process GO:0009164 112 0.011
epithelial cell migration GO:0010631 148 0.011
response to endogenous stimulus GO:0009719 119 0.011
Rat
camera type eye morphogenesis GO:0048593 2 0.011
detection of external stimulus GO:0009581 66 0.011
protein phosphorylation GO:0006468 169 0.011
response to extracellular stimulus GO:0009991 116 0.011
Rat
growth GO:0040007 359 0.011
response to organic cyclic compound GO:0014070 89 0.011
Rat
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
dorsal ventral axis specification GO:0009950 66 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
negative regulation of cell communication GO:0010648 223 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
embryonic morphogenesis GO:0048598 206 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
medium chain fatty acid metabolic process GO:0051791 1 0.011
synaptic transmission GO:0007268 288 0.011
negative regulation of transcription dna templated GO:0045892 237 0.011
developmental maturation GO:0021700 172 0.011
choline catabolic process GO:0042426 1 0.010
chromosome separation GO:0051304 42 0.010
antimicrobial humoral response GO:0019730 99 0.010
regulation of tube architecture open tracheal system GO:0035152 68 0.010
triglyceride catabolic process GO:0019433 3 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.010
mating behavior GO:0007617 106 0.010
ribonucleoside catabolic process GO:0042454 112 0.010
cellular biogenic amine catabolic process GO:0042402 1 0.010
cellular component assembly involved in morphogenesis GO:0010927 151 0.010
regulation of apoptotic process GO:0042981 130 0.010
very long chain fatty acid biosynthetic process GO:0042761 2 0.010
phototransduction GO:0007602 52 0.010
mitotic sister chromatid segregation GO:0000070 87 0.010
actin cytoskeleton organization GO:0030036 206 0.010
phosphatidylethanolamine metabolic process GO:0046337 1 0.010
acetylcholine catabolic process GO:0006581 1 0.010
purine ribonucleoside catabolic process GO:0046130 112 0.010
negative regulation of cell cycle GO:0045786 116 0.010
reproductive behavior GO:0019098 122 0.010
regulation of multi organism process GO:0043900 131 0.010
ribonucleotide metabolic process GO:0009259 145 0.010
digestive tract development GO:0048565 149 0.010
response to copper ion GO:0046688 4 0.010
carbohydrate derivative biosynthetic process GO:1901137 85 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010
defense response to gram negative bacterium GO:0050829 94 0.010
cytoplasmic transport GO:0016482 130 0.010
drinking behavior GO:0042756 2 0.010
limb morphogenesis GO:0035108 1 0.010
response to alcohol GO:0097305 95 0.010
Rat
cellularization GO:0007349 90 0.010
tissue migration GO:0090130 155 0.010
cellular response to hexose stimulus GO:0071331 1 0.010
regulation of phosphate metabolic process GO:0019220 210 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.010
anterior posterior pattern specification GO:0009952 136 0.010
oxidation reduction process GO:0055114 123 0.010
regulation of proteolysis GO:0030162 87 0.010
retina development in camera type eye GO:0060041 4 0.010
notch signaling pathway GO:0007219 120 0.010
dna metabolic process GO:0006259 227 0.010
lipid homeostasis GO:0055088 33 0.010
tripartite regional subdivision GO:0007351 103 0.010
protein catabolic process GO:0030163 101 0.010
response to mercury ion GO:0046689 3 0.010
pigment metabolic process GO:0042440 84 0.010

CG5428 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
nervous system disease DOID:863 0 0.025
disease of metabolism DOID:0014667 0 0.025
artery disease DOID:0050828 0 0.017
vascular disease DOID:178 0 0.017
hypertension DOID:10763 0 0.017
cardiovascular system disease DOID:1287 0 0.017
acquired metabolic disease DOID:0060158 0 0.017
inherited metabolic disorder DOID:655 0 0.016
sensory system disease DOID:0050155 0 0.014
type 2 diabetes mellitus DOID:9352 0 0.014
glucose metabolism disease DOID:4194 0 0.014
diabetes mellitus DOID:9351 0 0.014
carbohydrate metabolism disease DOID:0050013 0 0.014
essential hypertension DOID:10825 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
central nervous system disease DOID:331 0 0.011
urinary system disease DOID:18 0 0.010
musculoskeletal system disease DOID:17 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
cancer DOID:162 0 0.010