Drosophila melanogaster

60 known processes

robo3 (Dmel_CG5423)

CG5423 gene product from transcript CG5423-RA

(Aliases: Robo 3,Dmel\CG5423,Robo-3,ROBO3,CT17158,CG5423,CG14345,dRobo-3,Robo3)

robo3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of axon extension involved in axon guidance GO:0048841 4 0.986
Zebrafish
neuron recognition GO:0008038 101 0.985
retinal ganglion cell axon guidance GO:0031290 12 0.982
Zebrafish Mouse
regulation of dendrite morphogenesis GO:0048814 28 0.973
Rat
axonogenesis GO:0007409 290 0.960
dendrite guidance GO:0070983 21 0.958
Fly
axon development GO:0061564 297 0.957
head development GO:0060322 135 0.937
synapse organization GO:0050808 196 0.903
Zebrafish
regulation of axon guidance GO:1902667 10 0.885
Zebrafish
cell recognition GO:0008037 102 0.857
positive regulation of axonogenesis GO:0050772 2 0.850
Human
neuron projection guidance GO:0097485 241 0.816
positive regulation of nervous system development GO:0051962 69 0.808
Human
central nervous system development GO:0007417 201 0.804
regulation of neurogenesis GO:0050767 158 0.803
Human Zebrafish Rat Fly
photoreceptor cell axon guidance GO:0072499 23 0.801
Fly
axon midline choice point recognition GO:0016199 26 0.793
Zebrafish Mouse Rat Fly
dendrite development GO:0016358 204 0.771
Rat Fly
synapse assembly GO:0007416 143 0.762
Zebrafish
axon choice point recognition GO:0016198 26 0.743
Zebrafish Mouse Rat Fly
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.711
Human
taxis GO:0042330 304 0.705
positive regulation of neurogenesis GO:0050769 41 0.701
Human
dendrite morphogenesis GO:0048813 199 0.673
Rat Fly
positive regulation of developmental process GO:0051094 143 0.662
Human
localization of cell GO:0051674 257 0.644
Human Zebrafish Mouse Worm Fly
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.639
Human
regulation of dendrite development GO:0050773 37 0.613
Rat Fly
positive regulation of cell projection organization GO:0031346 29 0.601
Human
cell migration GO:0016477 238 0.601
Human Zebrafish Mouse Worm Fly
positive regulation of cellular component organization GO:0051130 156 0.600
Human
regulation of behavior GO:0050795 75 0.577
Human Zebrafish
biological adhesion GO:0022610 138 0.549
Human Zebrafish Fly
regulation of multicellular organismal development GO:2000026 414 0.549
Human Zebrafish Rat Fly
positive regulation of cell differentiation GO:0045597 64 0.536
Human
regulation of cell projection organization GO:0031344 92 0.532
Human Zebrafish Rat Fly
regulation of anatomical structure size GO:0090066 163 0.521
Zebrafish
telencephalon development GO:0021537 2 0.489
Human Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.473
Human Zebrafish Rat
central complex development GO:0048036 9 0.462
regulation of cell proliferation GO:0042127 163 0.460
Human Mouse
brain development GO:0007420 120 0.453
regulation of cell development GO:0060284 215 0.426
Human Zebrafish Rat Fly
cell cell adhesion GO:0098609 26 0.425
Human
dendrite self avoidance GO:0070593 8 0.421
regulation of cell differentiation GO:0045595 302 0.414
Human Zebrafish Rat Fly
positive regulation of cell development GO:0010720 61 0.405
Human
positive regulation of multicellular organismal process GO:0051240 143 0.400
Human
positive regulation of neuron differentiation GO:0045666 26 0.384
Human
regulation of cellular component biogenesis GO:0044087 201 0.381
Zebrafish
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.380
regulation of neuron differentiation GO:0045664 103 0.374
Human Zebrafish Rat Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.370
positive regulation of axon guidance GO:1902669 1 0.363
growth GO:0040007 359 0.363
Zebrafish Mouse
axon guidance GO:0007411 233 0.362
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.350
positive regulation of signal transduction GO:0009967 223 0.343
Zebrafish
motor neuron axon guidance GO:0008045 58 0.341
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.338
Human
cardiac cell fate commitment GO:0060911 17 0.337
Fly
intracellular signal transduction GO:0035556 300 0.334
Zebrafish
regulation of synapse assembly GO:0051963 94 0.321
Zebrafish
synaptic target recognition GO:0008039 45 0.320
Fly
axon target recognition GO:0007412 16 0.312
ras protein signal transduction GO:0007265 88 0.312
Zebrafish
positive regulation of gene expression GO:0010628 290 0.310
chemotaxis GO:0006935 249 0.305
developmental growth GO:0048589 280 0.286
Zebrafish Mouse
stem cell differentiation GO:0048863 117 0.267
Fly
regulation of cytoskeleton organization GO:0051493 89 0.248
response to organic substance GO:0010033 284 0.245
Human
regulation of synapse organization GO:0050807 110 0.241
Zebrafish
positive regulation of response to stimulus GO:0048584 323 0.240
Zebrafish
regulation of cell growth GO:0001558 43 0.233
Zebrafish
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.233
cell proliferation GO:0008283 299 0.228
Human Mouse
regulation of neuron projection development GO:0010975 69 0.224
Human Zebrafish Rat Fly
convergent extension GO:0060026 2 0.224
Zebrafish
transcription from rna polymerase ii promoter GO:0006366 368 0.202
response to oxygen containing compound GO:1901700 200 0.197
positive regulation of biosynthetic process GO:0009891 316 0.196
axon extension involved in axon guidance GO:0048846 10 0.195
Zebrafish
negative regulation of axon extension GO:0030517 3 0.188
Zebrafish
regulation of actin cytoskeleton organization GO:0032956 42 0.185
compound eye development GO:0048749 307 0.183
cell motility GO:0048870 251 0.179
Human Zebrafish Mouse Worm Fly
developmental growth involved in morphogenesis GO:0060560 65 0.178
Zebrafish Mouse
positive regulation of transcription dna templated GO:0045893 266 0.175
neuroblast proliferation GO:0007405 74 0.171
regionalization GO:0003002 416 0.171
Zebrafish Fly
blastoderm segmentation GO:0007350 159 0.163
positive regulation of cellular biosynthetic process GO:0031328 316 0.162
regulation of synapse structure and activity GO:0050803 128 0.160
Zebrafish
positive regulation of developmental growth GO:0048639 62 0.159
actin filament based process GO:0030029 220 0.159
forebrain development GO:0030900 2 0.149
Human Mouse
axonal fasciculation GO:0007413 12 0.147
Zebrafish
negative regulation of growth GO:0045926 84 0.144
Zebrafish
ventral cord development GO:0007419 16 0.143
embryonic pattern specification GO:0009880 174 0.139
sensory organ morphogenesis GO:0090596 260 0.139
camera type eye development GO:0043010 4 0.137
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.136
Fly
gastrulation GO:0007369 70 0.135
cell growth GO:0016049 108 0.135
Zebrafish
regulation of cellular component movement GO:0051270 42 0.130
Zebrafish Mouse Fly
developmental cell growth GO:0048588 52 0.129
Zebrafish
ameboidal type cell migration GO:0001667 151 0.129
Human Zebrafish Fly
mushroom body development GO:0016319 70 0.126
regulation of protein metabolic process GO:0051246 256 0.125
Human
regulation of axonogenesis GO:0050770 32 0.121
Human Zebrafish
eye morphogenesis GO:0048592 260 0.121
negative regulation of rna metabolic process GO:0051253 251 0.119
positive regulation of rna biosynthetic process GO:1902680 266 0.116
regulation of localization GO:0032879 275 0.116
Zebrafish Mouse Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.116
axon extension GO:0048675 32 0.114
Zebrafish
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.112
Human
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.112
cell migration involved in gastrulation GO:0042074 9 0.112
negative regulation of nucleic acid templated transcription GO:1903507 240 0.109
camera type eye morphogenesis GO:0048593 2 0.107
regulation of catalytic activity GO:0050790 185 0.105
Human
epithelial cell migration open tracheal system GO:0007427 32 0.105
Fly
nucleobase containing small molecule metabolic process GO:0055086 174 0.098
regulation of nervous system development GO:0051960 248 0.097
Human Zebrafish Rat Fly
post embryonic appendage morphogenesis GO:0035120 385 0.097
retina development in camera type eye GO:0060041 4 0.096
dorsal ventral axon guidance GO:0033563 2 0.095
Worm
retina morphogenesis in camera type eye GO:0060042 2 0.095
negative regulation of nervous system development GO:0051961 92 0.091
Zebrafish
olfactory bulb axon guidance GO:0071678 3 0.091
metal ion transport GO:0030001 74 0.089
cellular response to organic substance GO:0071310 132 0.089
Human
negative regulation of multicellular organismal process GO:0051241 142 0.089
Human Zebrafish
establishment of cell polarity GO:0030010 40 0.086
positive regulation of cell communication GO:0010647 250 0.085
Zebrafish
single organism cell adhesion GO:0098602 47 0.084
Fly
regulation of developmental growth GO:0048638 174 0.083
Zebrafish
locomotory behavior GO:0007626 176 0.080
Fly
positive regulation of axon extension GO:0045773 2 0.079
cardioblast cell fate commitment GO:0042684 14 0.075
Fly
single organism behavior GO:0044708 391 0.075
negative regulation of cell proliferation GO:0008285 69 0.074
Human Mouse
organonitrogen compound metabolic process GO:1901564 318 0.074
outflow tract morphogenesis GO:0003151 4 0.073
Fly
positive regulation of rna metabolic process GO:0051254 271 0.072
tissue morphogenesis GO:0048729 297 0.072
Zebrafish Mouse
regulation of anatomical structure morphogenesis GO:0022603 242 0.072
Human Zebrafish Rat
positive regulation of signaling GO:0023056 243 0.072
Zebrafish
epithelial cell development GO:0002064 274 0.072
kidney epithelium development GO:0072073 3 0.071
Human Mouse
negative regulation of biosynthetic process GO:0009890 277 0.070
regulation of neural precursor cell proliferation GO:2000177 35 0.070
positive regulation of neuron projection development GO:0010976 14 0.070
Human
digestive tract development GO:0048565 149 0.069
regulation of intracellular signal transduction GO:1902531 236 0.068
Zebrafish
central nervous system neuron differentiation GO:0021953 8 0.068
Human Zebrafish Mouse
cell junction organization GO:0034330 57 0.068
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.068
regulation of cell morphogenesis GO:0022604 163 0.067
Human Zebrafish Rat
phosphorylation GO:0016310 294 0.067
respiratory system development GO:0060541 213 0.067
Fly
negative regulation of cell communication GO:0010648 223 0.066
Human
regulation of small gtpase mediated signal transduction GO:0051056 93 0.065
Zebrafish
retinal cone cell differentiation GO:0042670 2 0.065
nucleotide catabolic process GO:0009166 109 0.064
protein localization GO:0008104 284 0.063
neural precursor cell proliferation GO:0061351 75 0.062
cardiocyte differentiation GO:0035051 29 0.062
Fly
apical junction assembly GO:0043297 32 0.062
kidney development GO:0001822 3 0.062
Human Mouse
dorsal ventral pattern formation GO:0009953 133 0.062
Zebrafish
actin polymerization or depolymerization GO:0008154 31 0.061
stem cell development GO:0048864 79 0.061
leg disc development GO:0035218 92 0.061
neuromuscular junction development GO:0007528 149 0.061
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.061
multi organism behavior GO:0051705 175 0.060
regulation of actin filament based process GO:0032970 42 0.060
nephron tubule development GO:0072080 3 0.060
eye photoreceptor cell differentiation GO:0001754 145 0.059
synaptic growth at neuromuscular junction GO:0051124 119 0.059
positive regulation of phosphate metabolic process GO:0045937 139 0.058
axis specification GO:0009798 167 0.058
segmentation GO:0035282 207 0.058
regulation of stem cell proliferation GO:0072091 40 0.057
negative regulation of neuron death GO:1901215 18 0.057
columnar cuboidal epithelial cell development GO:0002066 249 0.057
anatomical structure homeostasis GO:0060249 97 0.057
Fly
regulation of mapk cascade GO:0043408 92 0.057
cell division GO:0051301 248 0.056
epithelial cell differentiation GO:0030855 322 0.055
neuron projection extension GO:1990138 32 0.055
Zebrafish
divalent inorganic cation transport GO:0072511 30 0.055
eye development GO:0001654 323 0.054
positive regulation of nucleic acid templated transcription GO:1903508 266 0.053
cell adhesion GO:0007155 136 0.053
Human Zebrafish Fly
stem cell proliferation GO:0072089 88 0.053
kidney morphogenesis GO:0060993 3 0.053
regulation of ras protein signal transduction GO:0046578 93 0.053
Zebrafish
cellular macromolecule localization GO:0070727 220 0.052
digestive tract morphogenesis GO:0048546 127 0.052
positive regulation of phosphorus metabolic process GO:0010562 139 0.052
regulation of growth GO:0040008 233 0.052
Zebrafish
epidermal cell differentiation GO:0009913 51 0.052
hindbrain development GO:0030902 2 0.051
regulation of molecular function GO:0065009 217 0.049
Human
positive regulation of molecular function GO:0044093 136 0.049
Human
substrate dependent cell migration GO:0006929 3 0.049
Human
negative regulation of rna biosynthetic process GO:1902679 240 0.047
regulation of phosphorus metabolic process GO:0051174 210 0.047
anterior posterior pattern specification GO:0009952 136 0.047
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.046
regulation of epithelial cell proliferation GO:0050678 4 0.046
Human
protein modification process GO:0036211 438 0.046
positive regulation of cell cell adhesion GO:0022409 9 0.046
Fly
neuron migration GO:0001764 5 0.046
Mouse Worm Fly
cell projection assembly GO:0030031 94 0.045
Zebrafish
negative regulation of neurogenesis GO:0050768 53 0.045
Zebrafish
neural retina development GO:0003407 4 0.045
regulation of cardioblast differentiation GO:0051890 9 0.044
protein complex biogenesis GO:0070271 201 0.044
imaginal disc derived wing morphogenesis GO:0007476 337 0.043
appendage development GO:0048736 401 0.043
adult behavior GO:0030534 137 0.043
establishment or maintenance of cell polarity GO:0007163 167 0.042
response to reactive oxygen species GO:0000302 24 0.041
organic substance catabolic process GO:1901575 308 0.041
glial cell migration GO:0008347 31 0.040
startle response GO:0001964 16 0.040
Fly
salivary gland development GO:0007431 162 0.040
Fly
positive chemotaxis GO:0050918 4 0.039
Mouse
cell cell junction assembly GO:0007043 38 0.039
spiracle morphogenesis open tracheal system GO:0035277 22 0.039
nephron morphogenesis GO:0072028 3 0.039
regulation of actin polymerization or depolymerization GO:0008064 27 0.038
determination of dorsal ventral asymmetry GO:0048262 3 0.038
Zebrafish
open tracheal system development GO:0007424 204 0.038
Fly
regulation of cellular component size GO:0032535 98 0.037
Zebrafish
carbohydrate derivative catabolic process GO:1901136 118 0.037
rho protein signal transduction GO:0007266 14 0.037
carbohydrate derivative metabolic process GO:1901135 217 0.036
cognition GO:0050890 141 0.036
digestive system development GO:0055123 149 0.035
regulation of neuroblast proliferation GO:1902692 34 0.035
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.035
reproductive behavior GO:0019098 122 0.034
regulation of membrane potential GO:0042391 35 0.034
regulation of chemotaxis GO:0050920 12 0.034
Human Zebrafish
small gtpase mediated signal transduction GO:0007264 88 0.034
Zebrafish
negative regulation of cell differentiation GO:0045596 143 0.033
Zebrafish
central nervous system projection neuron axonogenesis GO:0021952 6 0.032
Zebrafish
multi multicellular organism process GO:0044706 123 0.032
regulation of rac protein signal transduction GO:0035020 3 0.032
Zebrafish
cell junction assembly GO:0034329 42 0.032
negative regulation of gene expression GO:0010629 387 0.032
purine ribonucleotide catabolic process GO:0009154 109 0.032
death GO:0016265 284 0.031
Human
imaginal disc derived appendage development GO:0048737 399 0.031
establishment of localization in cell GO:0051649 402 0.031
response to other organism GO:0051707 293 0.031
gland development GO:0048732 191 0.031
Human Mouse Fly
leg disc morphogenesis GO:0007478 80 0.031
positive regulation of cytoskeleton organization GO:0051495 21 0.031
regulation of organelle organization GO:0033043 196 0.030
single organismal cell cell adhesion GO:0016337 45 0.030
Fly
response to endogenous stimulus GO:0009719 119 0.030
Human
regulation of locomotion GO:0040012 42 0.030
Human Zebrafish Mouse Fly
positive regulation of cellular catabolic process GO:0031331 95 0.030
convergent extension involved in gastrulation GO:0060027 2 0.030
glial cell differentiation GO:0010001 35 0.030
actin cytoskeleton organization GO:0030036 206 0.029
positive regulation of protein metabolic process GO:0051247 128 0.029
Human
salivary gland morphogenesis GO:0007435 145 0.028
muscle organ development GO:0007517 127 0.028
cellular protein localization GO:0034613 160 0.028
ion transport GO:0006811 145 0.028
negative regulation of response to stimulus GO:0048585 258 0.028
Human Zebrafish
response to alcohol GO:0097305 95 0.028
regulation of cell migration GO:0030334 22 0.028
Zebrafish Mouse Fly
protein ubiquitination GO:0016567 70 0.028
negative regulation of synapse assembly GO:0051964 39 0.027
Zebrafish
cellular homeostasis GO:0019725 80 0.027
Fly
nucleoside phosphate metabolic process GO:0006753 162 0.027
multi organism reproductive behavior GO:0044705 121 0.027
determination of bilateral symmetry GO:0009855 13 0.027
Zebrafish
photoreceptor cell differentiation GO:0046530 170 0.027
protein catabolic process GO:0030163 101 0.027
regulation of protein complex assembly GO:0043254 42 0.027
purine containing compound catabolic process GO:0072523 112 0.027
actin filament polymerization GO:0030041 27 0.026
ribonucleotide metabolic process GO:0009259 145 0.026
appendage morphogenesis GO:0035107 397 0.026
positive regulation of cellular component biogenesis GO:0044089 80 0.026
gliogenesis GO:0042063 80 0.026
signal transduction by phosphorylation GO:0023014 107 0.026
positive regulation of cell migration GO:0030335 2 0.026
nucleoside catabolic process GO:0009164 112 0.026
single organism biosynthetic process GO:0044711 206 0.026
imaginal disc derived appendage morphogenesis GO:0035114 395 0.025
epithelium migration GO:0090132 148 0.025
Human Zebrafish Fly
gtp metabolic process GO:0046039 72 0.025
synaptic transmission GO:0007268 288 0.025
Zebrafish
positive regulation of proteolysis GO:0045862 52 0.025
Human
small molecule metabolic process GO:0044281 305 0.025
regulation of protein phosphorylation GO:0001932 64 0.025
positive regulation of cellular protein metabolic process GO:0032270 118 0.025
Human
cellular response to hormone stimulus GO:0032870 44 0.024
Human
stem cell maintenance GO:0019827 67 0.024
negative regulation of signal transduction GO:0009968 206 0.024
Human
cell maturation GO:0048469 144 0.024
purine containing compound metabolic process GO:0072521 155 0.024
homeostatic process GO:0042592 199 0.024
Fly
regulation of rho gtpase activity GO:0032319 20 0.024
guanosine containing compound catabolic process GO:1901069 74 0.024
positive regulation of cell motility GO:2000147 3 0.024
negative regulation of transcription dna templated GO:0045892 237 0.024
positive regulation of intracellular signal transduction GO:1902533 116 0.024
Zebrafish
regulation of phosphate metabolic process GO:0019220 210 0.024
positive regulation of phosphorylation GO:0042327 87 0.023
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.023
Zebrafish
positive regulation of peptidase activity GO:0010952 29 0.023
Human
camera type eye photoreceptor cell differentiation GO:0060219 2 0.023
glandular epithelial cell differentiation GO:0002067 1 0.023
anterior posterior axis specification GO:0009948 109 0.023
regulation of cellular protein metabolic process GO:0032268 243 0.023
Human
response to ethanol GO:0045471 59 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.023
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.023
glycosyl compound metabolic process GO:1901657 127 0.023
regulation of proteolysis GO:0030162 87 0.023
Human
regulation of cell size GO:0008361 63 0.023
Zebrafish
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.023
negative chemotaxis GO:0050919 15 0.022
Human Mouse
epithelial tube morphogenesis GO:0060562 88 0.022
Mouse
apoptotic process GO:0006915 159 0.022
Human
cellular nitrogen compound catabolic process GO:0044270 165 0.022
gland morphogenesis GO:0022612 145 0.022
Mouse
circulatory system development GO:0072359 82 0.022
Human Zebrafish Fly
macromolecule catabolic process GO:0009057 161 0.022
mating behavior GO:0007617 106 0.021
mating behavior sex discrimination GO:0048047 7 0.021
regulation of cell cycle GO:0051726 291 0.021
establishment of spindle orientation GO:0051294 18 0.021
hair cell differentiation GO:0035315 47 0.021
divalent metal ion transport GO:0070838 26 0.021
positive regulation of dendrite morphogenesis GO:0050775 9 0.021
glycosyl compound catabolic process GO:1901658 112 0.021
protein depolymerization GO:0051261 31 0.021
purine nucleoside catabolic process GO:0006152 112 0.021
actin filament organization GO:0007015 126 0.021
positive regulation of growth GO:0045927 75 0.021
proteolysis GO:0006508 192 0.020
Human
purine nucleotide catabolic process GO:0006195 109 0.020
protein complex assembly GO:0006461 200 0.020
negative regulation of molecular function GO:0044092 51 0.020
embryonic morphogenesis GO:0048598 206 0.020
feeding behavior GO:0007631 50 0.020
intracellular transport GO:0046907 228 0.020
protein polymerization GO:0051258 42 0.020
spermatogenesis GO:0007283 200 0.020
negative regulation of signaling GO:0023057 219 0.020
Human
nephron tubule morphogenesis GO:0072078 3 0.020
central nervous system neuron development GO:0021954 8 0.020
Human Zebrafish Mouse
single organism catabolic process GO:0044712 228 0.020
positive regulation of ras protein signal transduction GO:0046579 43 0.020
Zebrafish
regulation of cellular catabolic process GO:0031329 157 0.020
stem cell division GO:0017145 69 0.020
regulation of nucleoside metabolic process GO:0009118 50 0.020
nucleobase containing compound catabolic process GO:0034655 165 0.019
epithelial structure maintenance GO:0010669 17 0.019
cell cell junction organization GO:0045216 55 0.019
wing disc morphogenesis GO:0007472 344 0.019
neurological system process GO:0050877 358 0.019
Fly
regulation of phosphorylation GO:0042325 147 0.019
periodic partitioning GO:0007365 29 0.019
cellular catabolic process GO:0044248 372 0.019
negative regulation of cellular metabolic process GO:0031324 382 0.019
specification of symmetry GO:0009799 13 0.019
Zebrafish
cardioblast cell fate specification GO:0042685 9 0.018
Fly
catabolic process GO:0009056 409 0.018
nephron epithelium development GO:0072009 3 0.018
behavioral response to ethanol GO:0048149 49 0.018
nucleus localization GO:0051647 34 0.018
regulation of axon extension GO:0030516 8 0.018
Zebrafish
regulation of nucleotide catabolic process GO:0030811 48 0.018
ribonucleotide catabolic process GO:0009261 109 0.018
epithelial cell migration GO:0010631 148 0.018
Human Zebrafish Fly
regulation of actin filament polymerization GO:0030833 25 0.018
cellular protein complex assembly GO:0043623 71 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
nucleotide metabolic process GO:0009117 161 0.018
regulation of actin filament length GO:0030832 27 0.017
positive regulation of epithelial cell differentiation GO:0030858 1 0.017
nucleoside phosphate catabolic process GO:1901292 110 0.017
positive regulation of hydrolase activity GO:0051345 78 0.017
Human
macromolecular complex disassembly GO:0032984 37 0.017
enteroendocrine cell differentiation GO:0035883 1 0.017
torso signaling pathway GO:0008293 21 0.017
glial cell development GO:0021782 27 0.017
body morphogenesis GO:0010171 2 0.017
organophosphate metabolic process GO:0019637 195 0.017
mesodermal cell migration GO:0008078 7 0.016
purine ribonucleotide metabolic process GO:0009150 145 0.016
positive regulation of dendrite development GO:1900006 9 0.016
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
sex differentiation GO:0007548 81 0.016
positive regulation of apoptotic process GO:0043065 47 0.016
Human
cardioblast differentiation GO:0010002 20 0.016
Fly
regulation of purine nucleotide metabolic process GO:1900542 62 0.016
establishment of tissue polarity GO:0007164 87 0.016
positive regulation of small gtpase mediated signal transduction GO:0051057 43 0.016
Zebrafish
negative regulation of cell fate specification GO:0009996 15 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
organonitrogen compound biosynthetic process GO:1901566 117 0.016
ribonucleoside metabolic process GO:0009119 127 0.016
regulation of tube architecture open tracheal system GO:0035152 68 0.016
regulation of cell substrate adhesion GO:0010810 2 0.015
Zebrafish
nephron epithelium morphogenesis GO:0072088 3 0.015
microtubule polymerization or depolymerization GO:0031109 39 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
Human
response to organic cyclic compound GO:0014070 89 0.015
response to organonitrogen compound GO:0010243 75 0.015
nucleoside metabolic process GO:0009116 127 0.015
regulation of cell shape GO:0008360 113 0.015
organic substance transport GO:0071702 257 0.015
calcium ion transport GO:0006816 24 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.015
response to oxidative stress GO:0006979 86 0.015
gonad development GO:0008406 50 0.015
neuroblast development GO:0014019 13 0.015
response to nitrogen compound GO:1901698 90 0.014
mapk cascade GO:0000165 107 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
rac protein signal transduction GO:0016601 3 0.014
Zebrafish
reproductive system development GO:0061458 74 0.014
response to glucose GO:0009749 2 0.014
protein complex disassembly GO:0043241 36 0.014
positive regulation of nucleotide metabolic process GO:0045981 55 0.014
morphogenesis of a polarized epithelium GO:0001738 93 0.014
hindgut morphogenesis GO:0007442 58 0.014
asymmetric cell division GO:0008356 37 0.014
neuron death GO:0070997 27 0.014
flight behavior GO:0007629 26 0.014
response to monosaccharide GO:0034284 4 0.014
negative regulation of programmed cell death GO:0043069 72 0.014
positive regulation of synapse assembly GO:0051965 29 0.013
programmed cell death GO:0012501 257 0.013
Human
organonitrogen compound catabolic process GO:1901565 128 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.013
Human
response to extracellular stimulus GO:0009991 116 0.013
response to alkaloid GO:0043279 26 0.013
male gamete generation GO:0048232 201 0.013
regulation of photoreceptor cell axon guidance GO:2000289 5 0.013
chaeta morphogenesis GO:0008407 42 0.013
neuron maturation GO:0042551 31 0.013
purine nucleoside metabolic process GO:0042278 127 0.013
negative regulation of behavior GO:0048521 8 0.013
Human Zebrafish
positive regulation of gtp catabolic process GO:0033126 43 0.013
gtp catabolic process GO:0006184 72 0.013
actin filament bundle organization GO:0061572 28 0.013
embryonic axis specification GO:0000578 107 0.013
cell fate specification GO:0001708 71 0.013
Fly
cellular response to oxygen containing compound GO:1901701 79 0.013
positive regulation of gtpase activity GO:0043547 43 0.013
cellular amine metabolic process GO:0044106 12 0.013
positive regulation of locomotion GO:0040017 8 0.013
neuroblast division GO:0055057 35 0.012
detection of stimulus GO:0051606 156 0.012
regulation of ras gtpase activity GO:0032318 38 0.012
cation transport GO:0006812 110 0.012
protein modification by small protein conjugation or removal GO:0070647 106 0.012
lamellipodium organization GO:0097581 21 0.012
Zebrafish
skin development GO:0043588 65 0.012
regulation of extent of cell growth GO:0061387 8 0.012
Zebrafish
hemocyte differentiation GO:0042386 38 0.012
amine metabolic process GO:0009308 12 0.012
positive regulation of neural precursor cell proliferation GO:2000179 8 0.012
positive regulation of nucleoside metabolic process GO:0045979 47 0.012
establishment of mitotic spindle localization GO:0040001 17 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.012
chaeta development GO:0022416 97 0.012
maintenance of presynaptic active zone structure GO:0048790 8 0.012
negative regulation of protein depolymerization GO:1901880 23 0.011
spindle localization GO:0051653 22 0.011
muscle cell migration GO:0014812 3 0.011
regulation of microtubule based process GO:0032886 49 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011

robo3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.065
disease of anatomical entity DOID:7 0 0.065
Human
eye and adnexa disease DOID:1492 0 0.065
nervous system disease DOID:863 0 0.065
urinary system disease DOID:18 0 0.013
Human