Drosophila melanogaster

41 known processes

Rox8 (Dmel_CG5422)

CG5422 gene product from transcript CG5422-RD

(Aliases: RRM12,Dmel\CG5422,ROX8,rrm12,Rbp12,TIAR,CG5422,dTIAR,DmTIAR,rox8)

Rox8 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular macromolecule catabolic process GO:0044265 136 0.253
Yeast
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.174
protein localization GO:0008104 284 0.117
cellular protein modification process GO:0006464 438 0.116
cellular catabolic process GO:0044248 372 0.113
Yeast
modification dependent macromolecule catabolic process GO:0043632 79 0.112
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.101
positive regulation of gene expression GO:0010628 290 0.095
wing disc morphogenesis GO:0007472 344 0.090
aromatic compound catabolic process GO:0019439 166 0.077
Yeast
defense response GO:0006952 300 0.076
regulation of intracellular signal transduction GO:1902531 236 0.075
protein modification process GO:0036211 438 0.073
organic substance transport GO:0071702 257 0.068
transcription from rna polymerase ii promoter GO:0006366 368 0.068
positive regulation of nucleic acid templated transcription GO:1903508 266 0.068
central nervous system development GO:0007417 201 0.067
morphogenesis of an epithelium GO:0002009 276 0.066
regulation of cell cycle GO:0051726 291 0.063
regulation of localization GO:0032879 275 0.063
protein modification by small protein conjugation GO:0032446 79 0.062
catabolic process GO:0009056 409 0.060
Yeast
regulation of proteolysis GO:0030162 87 0.060
positive regulation of transcription dna templated GO:0045893 266 0.059
regulation of proteasomal protein catabolic process GO:0061136 39 0.059
cellular protein localization GO:0034613 160 0.059
positive regulation of rna metabolic process GO:0051254 271 0.055
intracellular signal transduction GO:0035556 300 0.051
positive regulation of biosynthetic process GO:0009891 316 0.051
negative regulation of response to stimulus GO:0048585 258 0.050
positive regulation of rna biosynthetic process GO:1902680 266 0.049
phosphorylation GO:0016310 294 0.048
regulation of cellular protein catabolic process GO:1903362 44 0.047
modification dependent protein catabolic process GO:0019941 78 0.047
single organism catabolic process GO:0044712 228 0.045
protein localization to organelle GO:0033365 82 0.045
negative regulation of signal transduction GO:0009968 206 0.044
cellular nitrogen compound catabolic process GO:0044270 165 0.044
Yeast
macromolecule catabolic process GO:0009057 161 0.044
Yeast
tube development GO:0035295 244 0.043
proteolysis GO:0006508 192 0.043
cellular macromolecule localization GO:0070727 220 0.043
negative regulation of nucleic acid templated transcription GO:1903507 240 0.042
response to light stimulus GO:0009416 124 0.042
ubiquitin dependent protein catabolic process GO:0006511 78 0.041
establishment or maintenance of cell polarity GO:0007163 167 0.040
positive regulation of cellular biosynthetic process GO:0031328 316 0.039
negative regulation of rna metabolic process GO:0051253 251 0.039
homeostatic process GO:0042592 199 0.038
response to biotic stimulus GO:0009607 294 0.038
single organism behavior GO:0044708 391 0.038
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.038
protein catabolic process GO:0030163 101 0.038
negative regulation of signaling GO:0023057 219 0.037
establishment of localization in cell GO:0051649 402 0.036
proteasomal protein catabolic process GO:0010498 59 0.035
response to organic substance GO:0010033 284 0.035
positive regulation of response to stimulus GO:0048584 323 0.034
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.034
positive regulation of signal transduction GO:0009967 223 0.034
regulation of cell differentiation GO:0045595 302 0.033
positive regulation of cell communication GO:0010647 250 0.032
head development GO:0060322 135 0.032
positive regulation of multicellular organismal process GO:0051240 143 0.032
embryonic morphogenesis GO:0048598 206 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.031
cell cell signaling involved in cell fate commitment GO:0045168 210 0.030
regulation of cellular component biogenesis GO:0044087 201 0.030
nuclear transport GO:0051169 72 0.030
death GO:0016265 284 0.029
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.029
growth GO:0040007 359 0.029
Worm
cell motility GO:0048870 251 0.028
mrna metabolic process GO:0016071 124 0.028
lateral inhibition GO:0046331 206 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.028
phagocytosis GO:0006909 215 0.027
regulation of mapk cascade GO:0043408 92 0.026
regulation of cellular catabolic process GO:0031329 157 0.026
response to abiotic stimulus GO:0009628 341 0.026
positive regulation of developmental process GO:0051094 143 0.025
taxis GO:0042330 304 0.025
axon guidance GO:0007411 233 0.025
brain development GO:0007420 120 0.024
regulation of transport GO:0051049 181 0.023
regulation of protein metabolic process GO:0051246 256 0.023
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.023
protein complex assembly GO:0006461 200 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.022
jak stat cascade GO:0007259 49 0.022
regulation of protein catabolic process GO:0042176 55 0.022
negative regulation of cell communication GO:0010648 223 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.022
multicellular organismal aging GO:0010259 140 0.022
response to endogenous stimulus GO:0009719 119 0.022
organic cyclic compound catabolic process GO:1901361 168 0.021
Yeast
regulation of multicellular organismal development GO:2000026 414 0.021
cardiovascular system development GO:0072358 82 0.021
response to other organism GO:0051707 293 0.021
intracellular transport GO:0046907 228 0.021
endocytosis GO:0006897 310 0.021
negative regulation of cellular biosynthetic process GO:0031327 277 0.021
Mouse
positive regulation of cellular protein metabolic process GO:0032270 118 0.020
regulation of organelle organization GO:0033043 196 0.020
cell division GO:0051301 248 0.020
Mouse
purine nucleotide metabolic process GO:0006163 146 0.020
positive regulation of intracellular signal transduction GO:1902533 116 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.020
mrna processing GO:0006397 104 0.019
neurological system process GO:0050877 358 0.019
immune system process GO:0002376 347 0.019
post embryonic appendage morphogenesis GO:0035120 385 0.019
protein transport GO:0015031 155 0.019
cell proliferation GO:0008283 299 0.019
Mouse
circulatory system development GO:0072359 82 0.019
cell adhesion GO:0007155 136 0.018
cytoplasmic transport GO:0016482 130 0.018
protein ubiquitination GO:0016567 70 0.018
vesicle mediated transport GO:0016192 381 0.018
negative regulation of protein metabolic process GO:0051248 85 0.018
Mouse
regulation of growth GO:0040008 233 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.017
regulation of cellular localization GO:0060341 136 0.017
regulation of catalytic activity GO:0050790 185 0.017
chemotaxis GO:0006935 249 0.017
muscle structure development GO:0061061 224 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.016
Yeast
response to radiation GO:0009314 155 0.016
stem cell proliferation GO:0072089 88 0.016
mitotic cell cycle checkpoint GO:0007093 88 0.016
protein phosphorylation GO:0006468 169 0.016
developmental growth GO:0048589 280 0.016
regulation of mrna processing GO:0050684 71 0.015
axonogenesis GO:0007409 290 0.015
intracellular protein transport GO:0006886 104 0.015
nucleotide metabolic process GO:0009117 161 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
rna processing GO:0006396 147 0.015
regulation of immune effector process GO:0002697 52 0.015
appendage morphogenesis GO:0035107 397 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
positive regulation of protein catabolic process GO:0045732 34 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
Mouse
cell death GO:0008219 279 0.014
cell migration GO:0016477 238 0.014
nucleoside triphosphate metabolic process GO:0009141 120 0.014
nitrogen compound transport GO:0071705 85 0.014
wing disc pattern formation GO:0035222 66 0.014
nuclear pore organization GO:0006999 1 0.014
cellular protein catabolic process GO:0044257 83 0.014
dorsal ventral pattern formation GO:0009953 133 0.014
regulation of developmental growth GO:0048638 174 0.014
regulation of cytoplasmic transport GO:1903649 47 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
tissue morphogenesis GO:0048729 297 0.013
nucleus organization GO:0006997 45 0.013
regulation of establishment of protein localization GO:0070201 61 0.013
mitotic nuclear division GO:0007067 213 0.013
organonitrogen compound metabolic process GO:1901564 318 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
stem cell development GO:0048864 79 0.013
determination of adult lifespan GO:0008340 137 0.012
behavioral response to ethanol GO:0048149 49 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
Mouse
epithelial cell development GO:0002064 274 0.012
negative regulation of cell cycle GO:0045786 116 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
negative regulation of neuron death GO:1901215 18 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
Mouse
regulation of intracellular transport GO:0032386 64 0.012
morphogenesis of embryonic epithelium GO:0016331 94 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.011
positive regulation of catabolic process GO:0009896 105 0.011
histone deubiquitination GO:0016578 8 0.011
imaginal disc derived appendage morphogenesis GO:0035114 395 0.011
nucleobase containing compound transport GO:0015931 56 0.011
single organism intracellular transport GO:1902582 207 0.011
adult behavior GO:0030534 137 0.011
negative regulation of protein binding GO:0032091 1 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
Mouse
regulation of response to stress GO:0080134 200 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
organic substance catabolic process GO:1901575 308 0.011
Yeast
regulation of cellular response to stress GO:0080135 89 0.011
negative regulation of phosphatase activity GO:0010923 3 0.011
positive regulation of signaling GO:0023056 243 0.010
regulation of protein localization GO:0032880 76 0.010
response to alcohol GO:0097305 95 0.010
stem cell differentiation GO:0048863 117 0.010
negative regulation of developmental process GO:0051093 201 0.010
mapk cascade GO:0000165 107 0.010
multi organism behavior GO:0051705 175 0.010
covalent chromatin modification GO:0016569 106 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
Worm

Rox8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021