Drosophila melanogaster

104 known processes

Ddc (Dmel_CG10697)

Dopa decarboxylase

(Aliases: l(2)37Ch,AADC,CG10697,HL9,l(2)37Bl,5-HT,l(2)k02104,ddc,fDDC,DdcDm,DDC,Dmel\CG10697)

Ddc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
phenol containing compound metabolic process GO:0018958 57 0.906
locomotory behavior GO:0007626 176 0.813
Worm Fly
phenol containing compound biosynthetic process GO:0046189 6 0.781
heart process GO:0003015 37 0.692
molting cycle chitin based cuticle GO:0007591 56 0.670
organic hydroxy compound metabolic process GO:1901615 83 0.642
heart contraction GO:0060047 26 0.617
cuticle pigmentation GO:0048067 22 0.543
organonitrogen compound biosynthetic process GO:1901566 117 0.530
tyrosine metabolic process GO:0006570 1 0.502
reproductive behavior GO:0019098 122 0.485
Worm Fly
cell migration GO:0016477 238 0.474
organonitrogen compound metabolic process GO:1901564 318 0.435
stem cell differentiation GO:0048863 117 0.434
catechol containing compound biosynthetic process GO:0009713 3 0.420
dopamine biosynthetic process from tyrosine GO:0006585 1 0.409
indole containing compound biosynthetic process GO:0042435 4 0.397
catecholamine biosynthetic process GO:0042423 3 0.391
tube development GO:0035295 244 0.390
negative regulation of rna biosynthetic process GO:1902679 240 0.381
pigmentation GO:0043473 75 0.378
negative regulation of cellular metabolic process GO:0031324 382 0.369
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.357
morphogenesis of an epithelium GO:0002009 276 0.348
embryonic morphogenesis GO:0048598 206 0.342
cuticle development GO:0042335 86 0.321
learning or memory GO:0007611 141 0.313
catechol containing compound metabolic process GO:0009712 10 0.300
epithelial cell migration GO:0010631 148 0.294
epithelial cell migration open tracheal system GO:0007427 32 0.294
regulation of blood circulation GO:1903522 21 0.285
muscle organ development GO:0007517 127 0.281
single organism biosynthetic process GO:0044711 206 0.277
regulation of epithelial cell proliferation GO:0050678 4 0.276
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.273
molting cycle GO:0042303 56 0.270
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.267
chitin based cuticle sclerotization GO:0007593 19 0.266
multi multicellular organism process GO:0044706 123 0.264
Worm Fly
heart development GO:0007507 82 0.263
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.260
digestive tract development GO:0048565 149 0.254
immune response GO:0006955 246 0.236
molting cycle process GO:0022404 29 0.235
muscle cell differentiation GO:0042692 103 0.234
central nervous system development GO:0007417 201 0.233
Zebrafish
organic hydroxy compound biosynthetic process GO:1901617 21 0.233
regulation of multicellular organismal development GO:2000026 414 0.226
negative regulation of developmental process GO:0051093 201 0.224
immune system process GO:0002376 347 0.212
transcription from rna polymerase ii promoter GO:0006366 368 0.205
regulation of chitin based cuticle tanning GO:0007564 14 0.192
negative regulation of gene expression GO:0010629 387 0.186
olfactory behavior GO:0042048 97 0.186
positive regulation of rna metabolic process GO:0051254 271 0.185
actin cytoskeleton organization GO:0030036 206 0.183
dopamine biosynthetic process GO:0042416 3 0.183
localization of cell GO:0051674 257 0.182
programmed cell death GO:0012501 257 0.182
positive regulation of macromolecule metabolic process GO:0010604 405 0.178
negative regulation of biosynthetic process GO:0009890 277 0.177
muscle structure development GO:0061061 224 0.176
negative regulation of cellular biosynthetic process GO:0031327 277 0.173
olfactory learning GO:0008355 56 0.167
striated muscle cell differentiation GO:0051146 90 0.165
regulation of cell differentiation GO:0045595 302 0.164
positive regulation of biosynthetic process GO:0009891 316 0.161
small molecule metabolic process GO:0044281 305 0.160
growth GO:0040007 359 0.160
multicellular organismal reproductive behavior GO:0033057 110 0.159
Worm Fly
cell motility GO:0048870 251 0.159
circulatory system process GO:0003013 37 0.158
positive regulation of response to stimulus GO:0048584 323 0.156
positive regulation of cellular biosynthetic process GO:0031328 316 0.155
striated muscle cell development GO:0055002 50 0.152
adult locomotory behavior GO:0008344 76 0.151
dopamine metabolic process GO:0042417 7 0.150
ameboidal type cell migration GO:0001667 151 0.147
mapk cascade GO:0000165 107 0.144
regulation of organ morphogenesis GO:2000027 78 0.141
regulation of heart contraction GO:0008016 21 0.141
post embryonic appendage morphogenesis GO:0035120 385 0.138
regulation of adult chitin containing cuticle pigmentation GO:0048082 13 0.136
cell proliferation GO:0008283 299 0.134
regulation of nervous system development GO:0051960 248 0.131
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.130
hematopoietic or lymphoid organ development GO:0048534 57 0.129
developmental programmed cell death GO:0010623 138 0.125
regulation of cuticle pigmentation GO:0048079 16 0.120
negative regulation of cellular component organization GO:0051129 108 0.120
pigment metabolic process GO:0042440 84 0.118
imaginal disc derived appendage development GO:0048737 399 0.118
single organism behavior GO:0044708 391 0.113
immune effector process GO:0002252 98 0.111
actomyosin structure organization GO:0031032 56 0.111
gonad development GO:0008406 50 0.107
learning GO:0007612 75 0.106
circulatory system development GO:0072359 82 0.105
sex differentiation GO:0007548 81 0.105
imaginal disc derived appendage morphogenesis GO:0035114 395 0.101
chemosensory behavior GO:0007635 106 0.100
positive regulation of transcription dna templated GO:0045893 266 0.100
blood circulation GO:0008015 26 0.100
neurological system process GO:0050877 358 0.099
negative regulation of rna metabolic process GO:0051253 251 0.096
response to oxygen containing compound GO:1901700 200 0.095
Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.094
negative regulation of transcription dna templated GO:0045892 237 0.093
cellular component assembly involved in morphogenesis GO:0010927 151 0.092
positive regulation of signaling GO:0023056 243 0.090
photoreceptor cell development GO:0042461 96 0.090
serotonin metabolic process GO:0042428 2 0.089
reproductive system development GO:0061458 74 0.088
head development GO:0060322 135 0.087
Zebrafish
positive regulation of catalytic activity GO:0043085 118 0.087
g protein coupled receptor signaling pathway GO:0007186 136 0.085
adult behavior GO:0030534 137 0.085
Fly
multi organism reproductive behavior GO:0044705 121 0.084
Worm Fly
eye morphogenesis GO:0048592 260 0.084
forebrain development GO:0030900 2 0.083
negative regulation of multicellular organismal process GO:0051241 142 0.083
phosphorylation GO:0016310 294 0.082
cellular amine metabolic process GO:0044106 12 0.080
compound eye pigmentation GO:0048072 17 0.080
regulation of localization GO:0032879 275 0.079
stem cell development GO:0048864 79 0.077
regulation of cell cycle GO:0051726 291 0.077
dendrite development GO:0016358 204 0.076
muscle tissue morphogenesis GO:0060415 2 0.076
positive regulation of nucleic acid templated transcription GO:1903508 266 0.076
regulation of molecular function GO:0065009 217 0.075
cellular protein modification process GO:0006464 438 0.075
regulation of anatomical structure morphogenesis GO:0022603 242 0.074
mitochondrion organization GO:0007005 65 0.074
eye photoreceptor cell differentiation GO:0001754 145 0.074
developmental pigmentation GO:0048066 68 0.072
positive regulation of multicellular organismal process GO:0051240 143 0.072
cellular catabolic process GO:0044248 372 0.072
regulation of protein metabolic process GO:0051246 256 0.071
vesicle mediated transport GO:0016192 381 0.070
Rat
regulation of phosphorus metabolic process GO:0051174 210 0.070
regulation of neurogenesis GO:0050767 158 0.070
development of primary sexual characteristics GO:0045137 50 0.069
amine metabolic process GO:0009308 12 0.069
connective tissue development GO:0061448 3 0.069
actin filament based process GO:0030029 220 0.068
urogenital system development GO:0001655 72 0.068
actin filament organization GO:0007015 126 0.068
defense response GO:0006952 300 0.067
wing disc morphogenesis GO:0007472 344 0.067
open tracheal system development GO:0007424 204 0.067
positive regulation of cell communication GO:0010647 250 0.067
digestive system development GO:0055123 149 0.067
response to temperature stimulus GO:0009266 106 0.067
stem cell proliferation GO:0072089 88 0.066
appendage morphogenesis GO:0035107 397 0.065
myofibril assembly GO:0030239 36 0.065
ovarian follicle cell development GO:0030707 248 0.065
aging GO:0007568 143 0.065
Rat
signal transduction by phosphorylation GO:0023014 107 0.064
spermatogenesis GO:0007283 200 0.064
columnar cuboidal epithelial cell development GO:0002066 249 0.064
death GO:0016265 284 0.064
negative regulation of nervous system development GO:0051961 92 0.064
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.063
eye development GO:0001654 323 0.063
body morphogenesis GO:0010171 2 0.063
innate immune response GO:0045087 144 0.062
organic substance catabolic process GO:1901575 308 0.061
regulation of cell cycle process GO:0010564 181 0.060
melanin metabolic process GO:0006582 47 0.060
tissue morphogenesis GO:0048729 297 0.060
intracellular signal transduction GO:0035556 300 0.060
embryonic organ development GO:0048568 50 0.058
cell fate specification GO:0001708 71 0.058
regulation of catalytic activity GO:0050790 185 0.057
cardiovascular system development GO:0072358 82 0.057
primary amino compound biosynthetic process GO:1901162 2 0.057
regulation of cellular catabolic process GO:0031329 157 0.057
mesoderm development GO:0007498 78 0.057
cellular response to organic substance GO:0071310 132 0.057
Rat
regulation of phosphate metabolic process GO:0019220 210 0.056
ion transport GO:0006811 145 0.055
dna replication GO:0006260 48 0.055
multi organism behavior GO:0051705 175 0.054
Worm Fly
muscle cell development GO:0055001 50 0.054
regulation of response to stress GO:0080134 200 0.053
dna metabolic process GO:0006259 227 0.052
stress activated mapk cascade GO:0051403 52 0.052
cell division GO:0051301 248 0.051
establishment of localization in cell GO:0051649 402 0.051
Rat
carboxylic acid metabolic process GO:0019752 92 0.050
protein modification process GO:0036211 438 0.050
regulation of cell migration GO:0030334 22 0.050
regulation of transport GO:0051049 181 0.049
apoptotic process involved in morphogenesis GO:0060561 3 0.049
male courtship behavior GO:0008049 63 0.048
negative regulation of phosphate metabolic process GO:0045936 45 0.048
compound eye photoreceptor cell differentiation GO:0001751 140 0.048
catabolic process GO:0009056 409 0.047
sensory organ morphogenesis GO:0090596 260 0.047
organophosphate metabolic process GO:0019637 195 0.047
cation homeostasis GO:0055080 51 0.045
embryo development ending in birth or egg hatching GO:0009792 152 0.045
regulation of cellular protein metabolic process GO:0032268 243 0.045
imaginal disc derived wing morphogenesis GO:0007476 337 0.044
regulation of cell morphogenesis GO:0022604 163 0.044
synaptic transmission dopaminergic GO:0001963 2 0.044
regulation of locomotion GO:0040012 42 0.043
negative regulation of cell cycle GO:0045786 116 0.043
epithelial cell differentiation GO:0030855 322 0.043
positive regulation of signal transduction GO:0009967 223 0.043
organic substance transport GO:0071702 257 0.043
Rat
regulation of anatomical structure size GO:0090066 163 0.042
positive regulation of gene expression GO:0010628 290 0.042
branching morphogenesis of an epithelial tube GO:0048754 45 0.042
epithelial tube morphogenesis GO:0060562 88 0.042
negative regulation of apoptotic process GO:0043066 63 0.041
germarium derived egg chamber formation GO:0007293 101 0.041
muscle system process GO:0003012 21 0.041
positive regulation of molecular function GO:0044093 136 0.040
protein transport GO:0015031 155 0.040
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.040
single organism catabolic process GO:0044712 228 0.040
camera type eye development GO:0043010 4 0.039
apoptotic process GO:0006915 159 0.039
single organism membrane organization GO:0044802 93 0.039
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.038
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.038
regulation of programmed cell death GO:0043067 152 0.038
negative regulation of programmed cell death GO:0043069 72 0.038
larval development GO:0002164 104 0.038
cell death GO:0008219 279 0.038
neuropeptide signaling pathway GO:0007218 45 0.038
macromolecule catabolic process GO:0009057 161 0.037
defense response to other organism GO:0098542 225 0.037
telencephalon development GO:0021537 2 0.037
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.037
cell cell signaling involved in cell fate commitment GO:0045168 210 0.037
cellular chemical homeostasis GO:0055082 40 0.036
response to wounding GO:0009611 94 0.036
mesoderm morphogenesis GO:0048332 22 0.036
cellular amino acid metabolic process GO:0006520 61 0.036
cellular cation homeostasis GO:0030003 38 0.036
adult chitin containing cuticle pigmentation GO:0048085 16 0.036
regulation of neuron apoptotic process GO:0043523 16 0.036
respiratory system development GO:0060541 213 0.036
hemocyte differentiation GO:0042386 38 0.035
regulation of organelle organization GO:0033043 196 0.035
regulation of response to external stimulus GO:0032101 115 0.035
limb development GO:0060173 1 0.035
organelle fission GO:0048285 340 0.034
eye photoreceptor cell development GO:0042462 81 0.033
cell fate determination GO:0001709 91 0.033
limb morphogenesis GO:0035108 1 0.032
circadian sleep wake cycle process GO:0022410 24 0.032
regulation of cellular amine metabolic process GO:0033238 3 0.032
rhythmic behavior GO:0007622 76 0.031
Fly
mesenchymal cell differentiation GO:0048762 1 0.031
regulation of developmental pigmentation GO:0048070 24 0.031
mating GO:0007618 120 0.031
Worm
neuron fate commitment GO:0048663 50 0.030
neuron neuron synaptic transmission GO:0007270 14 0.030
regulation of neuron differentiation GO:0045664 103 0.030
negative regulation of molecular function GO:0044092 51 0.030
regulation of apoptotic process GO:0042981 130 0.030
negative regulation of protein metabolic process GO:0051248 85 0.030
regulation of synaptic transmission GO:0050804 69 0.030
regulation of actin cytoskeleton organization GO:0032956 42 0.030
regulation of protein modification process GO:0031399 112 0.029
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.029
gastrulation GO:0007369 70 0.029
cell cycle phase transition GO:0044770 140 0.029
male mating behavior GO:0060179 70 0.028
Worm
ventral furrow formation GO:0007370 17 0.028
cation transport GO:0006812 110 0.028
compound eye development GO:0048749 307 0.028
tissue migration GO:0090130 155 0.028
negative regulation of cellular protein metabolic process GO:0032269 85 0.028
response to light stimulus GO:0009416 124 0.028
intracellular protein transport GO:0006886 104 0.027
regulation of cellular component movement GO:0051270 42 0.027
regulation of heart morphogenesis GO:2000826 3 0.027
positive regulation of cell death GO:0010942 69 0.027
male gamete generation GO:0048232 201 0.027
regulation of cell proliferation GO:0042127 163 0.027
secretion GO:0046903 109 0.027
regulation of cell cycle phase transition GO:1901987 130 0.026
multicellular organismal aging GO:0010259 140 0.026
Rat
digestive tract morphogenesis GO:0048546 127 0.026
regulation of mitotic cell cycle GO:0007346 190 0.026
formation of primary germ layer GO:0001704 24 0.026
immune system development GO:0002520 57 0.025
endocytosis GO:0006897 310 0.025
cell aging GO:0007569 2 0.024
circadian sleep wake cycle sleep GO:0050802 23 0.024
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.024
establishment of protein localization GO:0045184 163 0.024
regulation of dna templated transcription elongation GO:0032784 17 0.024
stress activated protein kinase signaling cascade GO:0031098 55 0.024
purine containing compound metabolic process GO:0072521 155 0.024
cellular ion homeostasis GO:0006873 39 0.023
regulation of cellular component size GO:0032535 98 0.023
organic acid metabolic process GO:0006082 103 0.023
positive regulation of protein transport GO:0051222 37 0.023
regulation of system process GO:0044057 36 0.023
regulation of cellular response to stress GO:0080135 89 0.023
appendage development GO:0048736 401 0.023
oviposition GO:0018991 19 0.023
Worm Fly
positive regulation of cellular protein metabolic process GO:0032270 118 0.023
cellular metal ion homeostasis GO:0006875 31 0.023
lipid metabolic process GO:0006629 121 0.023
morphogenesis of a branching epithelium GO:0061138 45 0.023
nucleobase containing compound catabolic process GO:0034655 165 0.023
mesenchymal cell development GO:0014031 1 0.023
establishment or maintenance of cell polarity GO:0007163 167 0.023
metal ion transport GO:0030001 74 0.023
dna templated transcription elongation GO:0006354 18 0.022
regulation of multi organism process GO:0043900 131 0.022
peptidyl lysine acetylation GO:0018394 39 0.022
negative regulation of cell proliferation GO:0008285 69 0.022
lipid storage GO:0019915 38 0.022
peptidyl amino acid modification GO:0018193 105 0.022
regionalization GO:0003002 416 0.022
protein phosphorylation GO:0006468 169 0.022
ethanolamine containing compound metabolic process GO:0042439 4 0.022
posttranscriptional regulation of gene expression GO:0010608 145 0.022
regulation of mitotic cell cycle phase transition GO:1901990 130 0.021
terminal branching open tracheal system GO:0007430 17 0.021
regulation of immune system process GO:0002682 176 0.021
epithelium migration GO:0090132 148 0.021
positive regulation of phosphate metabolic process GO:0045937 139 0.021
regulation of reproductive process GO:2000241 54 0.021
mating behavior sex discrimination GO:0048047 7 0.021
cellular divalent inorganic cation homeostasis GO:0072503 23 0.021
positive regulation of intracellular signal transduction GO:1902533 116 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.021
negative regulation of phosphorus metabolic process GO:0010563 45 0.021
negative regulation of nucleic acid templated transcription GO:1903507 240 0.020
lateral inhibition GO:0046331 206 0.020
instar larval development GO:0002168 55 0.020
negative regulation of cell death GO:0060548 81 0.020
positive regulation of cellular component organization GO:0051130 156 0.020
negative regulation of neurogenesis GO:0050768 53 0.020
hematopoietic progenitor cell differentiation GO:0002244 1 0.020
axon development GO:0061564 297 0.020
ovulation GO:0030728 4 0.019
somatic stem cell division GO:0048103 37 0.019
negative regulation of immune system process GO:0002683 50 0.019
notch signaling pathway GO:0007219 120 0.019
chromosome organization GO:0051276 360 0.019
brain development GO:0007420 120 0.019
Zebrafish
photoreceptor cell fate commitment GO:0046552 41 0.019
sarcomere organization GO:0045214 26 0.019
cellular homeostasis GO:0019725 80 0.019
negative regulation of epithelial cell proliferation GO:0050680 4 0.019
primary amino compound metabolic process GO:1901160 2 0.019
cell maturation GO:0048469 144 0.018
neurotransmitter receptor metabolic process GO:0045213 3 0.018
regulation of developmental growth GO:0048638 174 0.018
gland development GO:0048732 191 0.018
positive regulation of mapk cascade GO:0043410 63 0.018
protein complex biogenesis GO:0070271 201 0.018
positive regulation of execution phase of apoptosis GO:1900119 4 0.018
negative regulation of cell cycle process GO:0010948 109 0.018
macromolecule deacylation GO:0098732 11 0.018
peptide metabolic process GO:0006518 80 0.018
salivary gland morphogenesis GO:0007435 145 0.018
oxoacid metabolic process GO:0043436 103 0.018
regulation of vesicle mediated transport GO:0060627 59 0.018
regulation of cytoskeleton organization GO:0051493 89 0.017
histone modification GO:0016570 106 0.017
organophosphate catabolic process GO:0046434 112 0.017
protein localization GO:0008104 284 0.017
developmental growth GO:0048589 280 0.017
purine ribonucleotide metabolic process GO:0009150 145 0.017
response to alcohol GO:0097305 95 0.017
covalent chromatin modification GO:0016569 106 0.017
compound eye morphogenesis GO:0001745 249 0.017
protein catabolic process GO:0030163 101 0.017
positive regulation of transport GO:0051050 92 0.017
ribonucleotide metabolic process GO:0009259 145 0.017
protein complex assembly GO:0006461 200 0.017
regulation of nucleotide metabolic process GO:0006140 62 0.017
regulation of circadian sleep wake cycle GO:0042749 25 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
regulation of membrane potential GO:0042391 35 0.017
renal system development GO:0072001 72 0.017
regulation of phosphorylation GO:0042325 147 0.016
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.016
macromolecular complex assembly GO:0065003 256 0.016
maintenance of location GO:0051235 73 0.016
negative regulation of cell differentiation GO:0045596 143 0.016
aromatic amino acid family metabolic process GO:0009072 3 0.016
cellular macromolecular complex assembly GO:0034622 153 0.016
response to growth factor GO:0070848 31 0.016
Rat
chromosome segregation GO:0007059 157 0.016
retina development in camera type eye GO:0060041 4 0.016
reproductive structure development GO:0048608 74 0.016
response to abiotic stimulus GO:0009628 341 0.016
pericardium development GO:0060039 2 0.016
cell type specific apoptotic process GO:0097285 38 0.016
regulation of behavior GO:0050795 75 0.016
cell adhesion GO:0007155 136 0.016
carbohydrate derivative metabolic process GO:1901135 217 0.016
dendrite morphogenesis GO:0048813 199 0.016
regulation of hydrolase activity GO:0051336 97 0.016
carbohydrate metabolic process GO:0005975 82 0.015
cellular lipid metabolic process GO:0044255 83 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
single organism intracellular transport GO:1902582 207 0.015
regulation of synaptic plasticity GO:0048167 14 0.015
taxis GO:0042330 304 0.015
response to organic substance GO:0010033 284 0.015
Rat Fly
hindbrain development GO:0030902 2 0.015
positive regulation of developmental process GO:0051094 143 0.015
renal tubule morphogenesis GO:0061333 44 0.015
heterocycle catabolic process GO:0046700 166 0.015
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.015
trachea development GO:0060438 29 0.015
compound eye photoreceptor fate commitment GO:0001752 36 0.014
muscle fiber development GO:0048747 12 0.014
wound healing GO:0042060 75 0.014
nuclear division GO:0000280 332 0.014
renal tubule development GO:0061326 64 0.014
dna dependent dna replication GO:0006261 17 0.014
positive regulation of cell proliferation GO:0008284 47 0.014
embryonic pattern specification GO:0009880 174 0.014
response to ionizing radiation GO:0010212 32 0.014
developmental maturation GO:0021700 172 0.014
germ line stem cell maintenance GO:0030718 50 0.014
mitotic cell cycle phase transition GO:0044772 138 0.014
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.014
striated muscle adaptation GO:0014888 1 0.014
regulation of hemocyte differentiation GO:0045610 22 0.014
embryonic axis specification GO:0000578 107 0.014
positive regulation of protein metabolic process GO:0051247 128 0.013
negative regulation of cell development GO:0010721 62 0.013
regulation of purine nucleotide metabolic process GO:1900542 62 0.013
branching involved in open tracheal system development GO:0060446 45 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
cell growth GO:0016049 108 0.013
regulation of endocytosis GO:0030100 37 0.013
response to lipopolysaccharide GO:0032496 4 0.013
nucleoside catabolic process GO:0009164 112 0.013
neuroblast proliferation GO:0007405 74 0.013
pigment biosynthetic process GO:0046148 36 0.013
indole containing compound metabolic process GO:0042430 5 0.013
positive regulation of apoptotic signaling pathway GO:2001235 4 0.013
neuron death GO:0070997 27 0.013
single organism carbohydrate metabolic process GO:0044723 72 0.013
spinal cord development GO:0021510 1 0.013
response to ecdysone GO:0035075 34 0.013
cytoplasmic transport GO:0016482 130 0.013
regulation of cell division GO:0051302 72 0.012
response to mechanical stimulus GO:0009612 28 0.012
response to other organism GO:0051707 293 0.012
gastrulation with mouth forming first GO:0001703 36 0.012
homeostatic process GO:0042592 199 0.012
regulation of cellular localization GO:0060341 136 0.012
neuron apoptotic process GO:0051402 17 0.012
camera type eye morphogenesis GO:0048593 2 0.012
response to external biotic stimulus GO:0043207 293 0.012
non sensory hair organization GO:0035316 47 0.012
aromatic compound catabolic process GO:0019439 166 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
cell cell junction organization GO:0045216 55 0.012
cell cycle arrest GO:0007050 4 0.012
secondary metabolic process GO:0019748 75 0.012
Rat
ribonucleoside metabolic process GO:0009119 127 0.012
epithelial cell development GO:0002064 274 0.012
larval behavior GO:0030537 42 0.012
eye pigmentation GO:0048069 43 0.012
tissue death GO:0016271 102 0.012
melanization defense response GO:0035006 45 0.012
oocyte differentiation GO:0009994 145 0.012
gastrulation involving germ band extension GO:0010004 36 0.012
regulation of neuron projection development GO:0010975 69 0.012
protein secretion GO:0009306 45 0.012
regulation of dna metabolic process GO:0051052 34 0.012
habituation GO:0046959 10 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012

Ddc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.037
musculoskeletal system disease DOID:17 0 0.025
disease of cellular proliferation DOID:14566 0 0.023
muscular disease DOID:0080000 0 0.022
muscle tissue disease DOID:66 0 0.022
cancer DOID:162 0 0.017
myopathy DOID:423 0 0.017
heart disease DOID:114 0 0.017
cardiomyopathy DOID:0050700 0 0.017
intrinsic cardiomyopathy DOID:0060036 0 0.017
cardiovascular system disease DOID:1287 0 0.017
organ system cancer DOID:0050686 0 0.014