Drosophila melanogaster

52 known processes

tra2 (Dmel_CG10128)

transformer 2

(Aliases: Tra2,Tra-2,tra-2,TRA-2,TRA 2,TRA2,CG10128,Dmel\CG10128)

tra2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of macromolecule metabolic process GO:0010604 405 0.763
Human
positive regulation of gene expression GO:0010628 290 0.688
Human
multi multicellular organism process GO:0044706 123 0.629
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.548
Human
positive regulation of biosynthetic process GO:0009891 316 0.445
positive regulation of rna metabolic process GO:0051254 271 0.422
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.401
negative regulation of rna metabolic process GO:0051253 251 0.359
negative regulation of cellular biosynthetic process GO:0031327 277 0.357
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.318
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.307
gene silencing GO:0016458 138 0.300
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.279
negative regulation of nucleic acid templated transcription GO:1903507 240 0.275
locomotory behavior GO:0007626 176 0.252
sex determination GO:0007530 18 0.243
positive regulation of nucleic acid templated transcription GO:1903508 266 0.235
intracellular signal transduction GO:0035556 300 0.224
negative regulation of biosynthetic process GO:0009890 277 0.221
negative regulation of cellular metabolic process GO:0031324 382 0.214
positive regulation of rna biosynthetic process GO:1902680 266 0.214
negative regulation of cell cycle GO:0045786 116 0.201
mrna processing GO:0006397 104 0.176
chromatin modification GO:0016568 147 0.167
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.167
oocyte differentiation GO:0009994 145 0.164
response to abiotic stimulus GO:0009628 341 0.148
response to oxygen containing compound GO:1901700 200 0.143
Rat
regulation of phosphorus metabolic process GO:0051174 210 0.141
negative regulation of rna biosynthetic process GO:1902679 240 0.139
negative regulation of mitotic cell cycle GO:0045930 109 0.136
positive regulation of cellular biosynthetic process GO:0031328 316 0.129
mitotic cell cycle phase transition GO:0044772 138 0.127
single organism behavior GO:0044708 391 0.127
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.124
positive regulation of phosphate metabolic process GO:0045937 139 0.123
spindle organization GO:0007051 253 0.118
transcription from rna polymerase ii promoter GO:0006366 368 0.115
regulation of cell cycle phase transition GO:1901987 130 0.115
regulation of cell cycle GO:0051726 291 0.113
mitotic nuclear division GO:0007067 213 0.111
axonogenesis GO:0007409 290 0.111
regulation of localization GO:0032879 275 0.107
regulation of phosphate metabolic process GO:0019220 210 0.106
posttranscriptional gene silencing by rna GO:0035194 45 0.104
phosphorylation GO:0016310 294 0.103
segmentation GO:0035282 207 0.100
cytoskeleton dependent cytokinesis GO:0061640 81 0.097
eye photoreceptor cell development GO:0042462 81 0.093
negative regulation of organelle organization GO:0010639 56 0.093
negative regulation of gene expression GO:0010629 387 0.090
imaginal disc growth GO:0007446 37 0.089
taxis GO:0042330 304 0.087
regulation of transport GO:0051049 181 0.087
sister chromatid segregation GO:0000819 92 0.087
regulation of multicellular organismal development GO:2000026 414 0.087
regulation of meiosis GO:0040020 3 0.086
mitotic cytokinesis GO:0000281 50 0.085
carbohydrate derivative metabolic process GO:1901135 217 0.085
dna damage checkpoint GO:0000077 78 0.083
reproductive system development GO:0061458 74 0.082
developmental programmed cell death GO:0010623 138 0.081
cognition GO:0050890 141 0.078
regulation of gene expression epigenetic GO:0040029 128 0.074
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.073
Human
multi organism behavior GO:0051705 175 0.068
establishment of localization in cell GO:0051649 402 0.066
nuclear division GO:0000280 332 0.066
positive regulation of transcription dna templated GO:0045893 266 0.064
regulation of ras protein signal transduction GO:0046578 93 0.061
single organism intracellular transport GO:1902582 207 0.061
cellular response to dna damage stimulus GO:0006974 223 0.061
chemotaxis GO:0006935 249 0.061
organophosphate metabolic process GO:0019637 195 0.060
posttranscriptional regulation of gene expression GO:0010608 145 0.059
neuron projection guidance GO:0097485 241 0.058
development of primary sexual characteristics GO:0045137 50 0.057
appendage morphogenesis GO:0035107 397 0.055
positive regulation of signaling GO:0023056 243 0.052
dna templated transcription initiation GO:0006352 25 0.052
regulation of mrna metabolic process GO:1903311 72 0.050
regulation of gene silencing GO:0060968 63 0.049
female sex differentiation GO:0046660 20 0.048
sensory organ morphogenesis GO:0090596 260 0.048
male gamete generation GO:0048232 201 0.048
cell death GO:0008219 279 0.047
regulation of cell cycle process GO:0010564 181 0.046
rna processing GO:0006396 147 0.046
mitotic sister chromatid segregation GO:0000070 87 0.045
chromatin organization GO:0006325 207 0.045
mitotic spindle organization GO:0007052 220 0.045
cell cycle phase transition GO:0044770 140 0.045
rna splicing GO:0008380 83 0.043
negative regulation of cell cycle process GO:0010948 109 0.043
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.043
sex differentiation GO:0007548 81 0.042
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.042
negative regulation of gene expression epigenetic GO:0045814 77 0.042
dna conformation change GO:0071103 105 0.042
negative regulation of meiotic cell cycle GO:0051447 2 0.042
mitotic g2 m transition checkpoint GO:0044818 70 0.042
regulation of intracellular signal transduction GO:1902531 236 0.041
cytoplasmic transport GO:0016482 130 0.041
chromatin remodeling GO:0006338 72 0.039
myofibril assembly GO:0030239 36 0.039
gonad development GO:0008406 50 0.039
oocyte development GO:0048599 124 0.038
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.038
negative regulation of cellular component organization GO:0051129 108 0.037
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.037
organelle fission GO:0048285 340 0.037
developmental maturation GO:0021700 172 0.036
regulation of mitotic cell cycle GO:0007346 190 0.036
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.035
regulation of meiotic cell cycle GO:0051445 9 0.035
developmental growth GO:0048589 280 0.035
multi organism reproductive behavior GO:0044705 121 0.034
imaginal disc derived appendage development GO:0048737 399 0.033
positive regulation of phosphorylation GO:0042327 87 0.032
axon guidance GO:0007411 233 0.032
chromatin mediated maintenance of transcription GO:0048096 7 0.032
organelle assembly GO:0070925 198 0.032
negative regulation of cellular catabolic process GO:0031330 34 0.031
response to external biotic stimulus GO:0043207 293 0.031
response to radiation GO:0009314 155 0.030
regulation of chromatin silencing GO:0031935 36 0.030
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.030
mrna splice site selection GO:0006376 1 0.030
regulation of protein modification process GO:0031399 112 0.030
nucleoside phosphate metabolic process GO:0006753 162 0.029
cellular component disassembly GO:0022411 46 0.029
ncrna metabolic process GO:0034660 43 0.029
germ cell migration GO:0008354 43 0.028
protein complex assembly GO:0006461 200 0.028
regulation of intracellular transport GO:0032386 64 0.028
spermatid development GO:0007286 98 0.028
mitotic dna integrity checkpoint GO:0044774 75 0.027
regulation of mitotic cell cycle phase transition GO:1901990 130 0.027
protein modification process GO:0036211 438 0.027
negative regulation of cell cycle phase transition GO:1901988 103 0.027
chromatin silencing GO:0006342 76 0.027
response to organic substance GO:0010033 284 0.027
negative regulation of transcription dna templated GO:0045892 237 0.027
regulation of rna splicing GO:0043484 69 0.026
mrna metabolic process GO:0016071 124 0.026
tissue morphogenesis GO:0048729 297 0.026
response to other organism GO:0051707 293 0.025
gene silencing by rna GO:0031047 57 0.025
g2 dna damage checkpoint GO:0031572 69 0.025
oocyte construction GO:0007308 112 0.024
regulation of molecular function GO:0065009 217 0.024
signal transduction by phosphorylation GO:0023014 107 0.024
positive regulation of cell communication GO:0010647 250 0.023
regulation of phosphorylation GO:0042325 147 0.023
single organism membrane organization GO:0044802 93 0.023
peptidyl amino acid modification GO:0018193 105 0.022
regulation of dna recombination GO:0000018 4 0.022
regulation of mapk cascade GO:0043408 92 0.022
regulation of erk1 and erk2 cascade GO:0070372 39 0.022
positive regulation of transcription factor import into nucleus GO:0042993 19 0.022
synapse organization GO:0050808 196 0.022
central nervous system development GO:0007417 201 0.021
regulation of cellular localization GO:0060341 136 0.021
multicellular organismal reproductive behavior GO:0033057 110 0.020
chromosome separation GO:0051304 42 0.020
cell maturation GO:0048469 144 0.020
axon development GO:0061564 297 0.020
protein localization GO:0008104 284 0.019
small molecule metabolic process GO:0044281 305 0.019
regulation of developmental growth GO:0048638 174 0.019
regionalization GO:0003002 416 0.019
meiotic cell cycle GO:0051321 171 0.019
regulation of cell division GO:0051302 72 0.019
response to bacterium GO:0009617 198 0.019
organic substance transport GO:0071702 257 0.018
endocytosis GO:0006897 310 0.018
positive regulation of molecular function GO:0044093 136 0.018
cellular protein complex disassembly GO:0043624 35 0.018
reproductive structure development GO:0048608 74 0.018
skin development GO:0043588 65 0.018
chromosome segregation GO:0007059 157 0.018
negative regulation of cell communication GO:0010648 223 0.018
positive regulation of developmental process GO:0051094 143 0.018
positive regulation of phosphorus metabolic process GO:0010562 139 0.018
camera type eye development GO:0043010 4 0.017
protein complex disassembly GO:0043241 36 0.017
poly a mrna export from nucleus GO:0016973 5 0.017
positive regulation of transport GO:0051050 92 0.017
embryo development ending in birth or egg hatching GO:0009792 152 0.016
mapk cascade GO:0000165 107 0.016
response to alcohol GO:0097305 95 0.016
defense response to other organism GO:0098542 225 0.016
germ line stem cell maintenance GO:0030718 50 0.016
negative regulation of cellular protein metabolic process GO:0032269 85 0.016
nucleoside metabolic process GO:0009116 127 0.016
positive regulation of signal transduction GO:0009967 223 0.016
positive regulation of intracellular transport GO:0032388 42 0.016
protein complex biogenesis GO:0070271 201 0.015
ubiquitin dependent protein catabolic process GO:0006511 78 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
regulation of wnt signaling pathway GO:0030111 68 0.015
spindle stabilization GO:0043146 14 0.014
embryonic development via the syncytial blastoderm GO:0001700 148 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
ion transport GO:0006811 145 0.014
spindle assembly involved in mitosis GO:0090307 50 0.014
membrane organization GO:0061024 112 0.014
anterior posterior pattern specification GO:0009952 136 0.013
posttranscriptional gene silencing GO:0016441 46 0.013
respiratory system development GO:0060541 213 0.013
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.013
synaptic growth at neuromuscular junction GO:0051124 119 0.013
proteasomal protein catabolic process GO:0010498 59 0.013
positive regulation of atp catabolic process GO:1903291 3 0.013
negative regulation of cell differentiation GO:0045596 143 0.013
maternal determination of anterior posterior axis embryo GO:0008358 74 0.013
extrinsic apoptotic signaling pathway GO:0097191 1 0.013
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.013
camera type eye morphogenesis GO:0048593 2 0.013
regulation of organelle organization GO:0033043 196 0.013
dna integrity checkpoint GO:0031570 81 0.012
heterocycle catabolic process GO:0046700 166 0.012
regulation of cell differentiation GO:0045595 302 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
chromosome organization GO:0051276 360 0.012
negative regulation of cardioblast differentiation GO:0051892 7 0.012
carbohydrate derivative biosynthetic process GO:1901137 85 0.012
genitalia development GO:0048806 26 0.011
regulation of cell development GO:0060284 215 0.011
cellular protein modification process GO:0006464 438 0.011
negative regulation of signaling GO:0023057 219 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
regulation of epidermal cell differentiation GO:0045604 3 0.011
regulation of multi organism process GO:0043900 131 0.011
cellular response to nutrient GO:0031670 1 0.011
regulation of sister chromatid segregation GO:0033045 28 0.011
histone h3 k4 methylation GO:0051568 16 0.011
positive regulation of mitotic cell cycle GO:0045931 34 0.011
cell division GO:0051301 248 0.011
positive regulation of multi organism process GO:0043902 40 0.010
positive regulation of cell cycle process GO:0090068 28 0.010
regulation of protein localization GO:0032880 76 0.010
regulation of cellular component movement GO:0051270 42 0.010
regulation of nuclear division GO:0051783 58 0.010
reproductive behavior GO:0019098 122 0.010
female gonad development GO:0008585 12 0.010
regulation of nervous system development GO:0051960 248 0.010
salivary gland histolysis GO:0035070 88 0.010
nucleotide catabolic process GO:0009166 109 0.010

tra2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.058
nervous system disease DOID:863 0 0.058