Drosophila melanogaster

91 known processes

MRP (Dmel_CG6214)

Multidrug-Resistance like Protein 1

(Aliases: Dmel\CG6214,dMRP/CG6214,CG6214,dMRP)

MRP biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 122 0.351
Yeast Rat
transmembrane transport GO:0055085 139 0.203
cation transmembrane transport GO:0098655 88 0.172
Yeast
inorganic cation transmembrane transport GO:0098662 61 0.164
Yeast
metal ion transport GO:0030001 74 0.153
Yeast
inorganic ion transmembrane transport GO:0098660 73 0.150
Yeast
anion transmembrane transport GO:0098656 26 0.110
Rat
cellular response to dna damage stimulus GO:0006974 223 0.090
protein complex assembly GO:0006461 200 0.089
homeostatic process GO:0042592 199 0.089
Yeast
regulation of transport GO:0051049 181 0.080
mrna metabolic process GO:0016071 124 0.074
organelle fission GO:0048285 340 0.071
nuclear division GO:0000280 332 0.070
vesicle mediated transport GO:0016192 381 0.066
cation transport GO:0006812 110 0.065
Yeast Rat
central nervous system development GO:0007417 201 0.062
negative regulation of developmental process GO:0051093 201 0.057
negative regulation of gene expression GO:0010629 387 0.057
macromolecular complex assembly GO:0065003 256 0.057
dna damage checkpoint GO:0000077 78 0.056
dorsal ventral pattern formation GO:0009953 133 0.054
ion transport GO:0006811 145 0.054
Yeast Rat
aging GO:0007568 143 0.053
response to abiotic stimulus GO:0009628 341 0.051
response to lipopolysaccharide GO:0032496 4 0.047
Rat
regulation of translation GO:0006417 56 0.047
single organism intracellular transport GO:1902582 207 0.047
protein complex biogenesis GO:0070271 201 0.046
regulation of cellular protein metabolic process GO:0032268 243 0.044
intracellular transport GO:0046907 228 0.040
cell cycle checkpoint GO:0000075 95 0.040
negative regulation of cell communication GO:0010648 223 0.037
cellular protein complex assembly GO:0043623 71 0.035
imaginal disc pattern formation GO:0007447 91 0.035
multicellular organismal aging GO:0010259 140 0.034
inorganic anion transmembrane transport GO:0098661 14 0.033
regionalization GO:0003002 416 0.032
negative regulation of multicellular organismal process GO:0051241 142 0.030
monovalent inorganic cation transport GO:0015672 40 0.029
endocytosis GO:0006897 310 0.029
muscle system process GO:0003012 21 0.027
protein transport GO:0015031 155 0.027
regulation of localization GO:0032879 275 0.027
Rat
posttranscriptional regulation of gene expression GO:0010608 145 0.025
regulation of cellular localization GO:0060341 136 0.025
centrosome cycle GO:0007098 137 0.025
organelle localization GO:0051640 148 0.024
g2 dna damage checkpoint GO:0031572 69 0.023
body morphogenesis GO:0010171 2 0.023
determination of adult lifespan GO:0008340 137 0.023
forebrain development GO:0030900 2 0.023
regulation of neurogenesis GO:0050767 158 0.022
maintenance of location GO:0051235 73 0.022
translation GO:0006412 69 0.022
establishment of localization in cell GO:0051649 402 0.022
response to copper ion GO:0046688 4 0.022
regulation of cell proliferation GO:0042127 163 0.022
establishment of protein localization GO:0045184 163 0.022
metal ion homeostasis GO:0055065 44 0.021
cell proliferation GO:0008283 299 0.021
cytoplasmic transport GO:0016482 130 0.021
dna integrity checkpoint GO:0031570 81 0.020
developmental growth GO:0048589 280 0.020
positive regulation of signal transduction GO:0009967 223 0.020
cell division GO:0051301 248 0.019
regulation of neuron differentiation GO:0045664 103 0.019
mrna catabolic process GO:0006402 33 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
positive regulation of gliogenesis GO:0014015 5 0.018
response to metal ion GO:0010038 23 0.018
Yeast
organic substance transport GO:0071702 257 0.018
Yeast Rat
negative regulation of signaling GO:0023057 219 0.018
regulation of cell cycle GO:0051726 291 0.018
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.018
immune response activating signal transduction GO:0002757 2 0.018
spindle organization GO:0007051 253 0.018
gland development GO:0048732 191 0.018
cellular homeostasis GO:0019725 80 0.018
Yeast
regulation of cell development GO:0060284 215 0.018
protein import GO:0017038 55 0.017
regulation of cell cycle process GO:0010564 181 0.017
eye development GO:0001654 323 0.017
protein targeting to nucleus GO:0044744 51 0.017
mitotic spindle organization GO:0007052 220 0.017
regulation of synapse structure and activity GO:0050803 128 0.017
regulation of cell differentiation GO:0045595 302 0.017
neurological system process GO:0050877 358 0.016
mitotic g2 m transition checkpoint GO:0044818 70 0.015
membrane organization GO:0061024 112 0.015
Yeast
single organism biosynthetic process GO:0044711 206 0.015
single organism behavior GO:0044708 391 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
protein localization to nucleus GO:0034504 55 0.014
intracellular protein transport GO:0006886 104 0.014
muscle structure development GO:0061061 224 0.014
telencephalon development GO:0021537 2 0.014
negative regulation of nervous system development GO:0051961 92 0.014
organ growth GO:0035265 56 0.014
protein targeting GO:0006605 64 0.014
chaperone mediated protein folding GO:0061077 2 0.014
response to other organism GO:0051707 293 0.013
Rat
wing disc pattern formation GO:0035222 66 0.013
negative regulation of signal transduction GO:0009968 206 0.013
regulation of protein metabolic process GO:0051246 256 0.013
adult behavior GO:0030534 137 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
stem cell differentiation GO:0048863 117 0.013
immune response regulating signaling pathway GO:0002764 2 0.013
regulation of intracellular transport GO:0032386 64 0.013
wing disc morphogenesis GO:0007472 344 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
biological adhesion GO:0022610 138 0.013
cellular ketone metabolic process GO:0042180 24 0.013
growth GO:0040007 359 0.013
larval development GO:0002164 104 0.013
eye morphogenesis GO:0048592 260 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
imaginal disc growth GO:0007446 37 0.013
proteolysis GO:0006508 192 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
Yeast
positive regulation of multi organism process GO:0043902 40 0.012
compound eye development GO:0048749 307 0.012
regulation of microtubule cytoskeleton organization GO:0070507 41 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
regulation of mrna metabolic process GO:1903311 72 0.012
regulation of ion transport GO:0043269 39 0.012
extracellular structure organization GO:0043062 46 0.012
anterior posterior axis specification GO:0009948 109 0.012
appendage morphogenesis GO:0035107 397 0.012
regulation of proteolysis GO:0030162 87 0.012
positive regulation of response to stimulus GO:0048584 323 0.011
amine metabolic process GO:0009308 12 0.011
negative regulation of cellular metabolic process GO:0031324 382 0.011
regulation of steroid metabolic process GO:0019218 2 0.011
centrosome duplication GO:0051298 121 0.011
single organism nuclear import GO:1902593 51 0.011
response to oxygen levels GO:0070482 59 0.011
notch signaling pathway GO:0007219 120 0.011
post embryonic appendage morphogenesis GO:0035120 385 0.011
negative regulation of smoothened signaling pathway GO:0045879 16 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
lateral inhibition GO:0046331 206 0.011
synaptic vesicle localization GO:0097479 53 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.010
establishment of protein localization to organelle GO:0072594 62 0.010
mrna processing GO:0006397 104 0.010
negative regulation of response to stimulus GO:0048585 258 0.010
regulation of mitosis GO:0007088 56 0.010

MRP disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
Human
nervous system disease DOID:863 0 0.015
central nervous system disease DOID:331 0 0.012