Drosophila melanogaster

63 known processes

Pak3 (Dmel_CG14895)

CG14895 gene product from transcript CG14895-RA

(Aliases: pak3,anon-WO0118547.285,CG14895,D-Pak3,DPAK3,dPAK3,Dmel\CG14895,PaK3,DmPAK3,DPak3,PAK3)

Pak3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synapse organization GO:0050808 196 0.952
actin filament based process GO:0030029 220 0.908
synapse assembly GO:0007416 143 0.815
dendrite development GO:0016358 204 0.796
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.686
regulation of synapse structure and activity GO:0050803 128 0.683
dendrite morphogenesis GO:0048813 199 0.660
centrosome duplication GO:0051298 121 0.638
neuromuscular junction development GO:0007528 149 0.629
regulation of synapse assembly GO:0051963 94 0.605
regulation of cytoskeleton organization GO:0051493 89 0.593
regulation of nervous system development GO:0051960 248 0.589
cellular protein complex disassembly GO:0043624 35 0.571
purine ribonucleoside catabolic process GO:0046130 112 0.525
purine nucleoside metabolic process GO:0042278 127 0.496
regulation of multicellular organismal development GO:2000026 414 0.495
regulation of synapse organization GO:0050807 110 0.454
vesicle mediated transport GO:0016192 381 0.438
regulation of cellular component biogenesis GO:0044087 201 0.416
syncytium formation by plasma membrane fusion GO:0000768 43 0.375
regulation of dendrite morphogenesis GO:0048814 28 0.361
nucleoside metabolic process GO:0009116 127 0.336
positive regulation of response to stimulus GO:0048584 323 0.333
Yeast
regulation of dendrite development GO:0050773 37 0.332
actin filament organization GO:0007015 126 0.332
small molecule metabolic process GO:0044281 305 0.331
growth GO:0040007 359 0.309
Yeast
spermatogenesis GO:0007283 200 0.297
actin cytoskeleton organization GO:0030036 206 0.286
embryonic development via the syncytial blastoderm GO:0001700 148 0.280
phagocytosis GO:0006909 215 0.268
actin filament bundle organization GO:0061572 28 0.266
positive regulation of cellular component biogenesis GO:0044089 80 0.263
synaptic growth at neuromuscular junction GO:0051124 119 0.262
regulation of protein complex disassembly GO:0043244 29 0.260
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.257
ovarian follicle cell development GO:0030707 248 0.254
myoblast fusion GO:0007520 43 0.253
organonitrogen compound metabolic process GO:1901564 318 0.253
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.247
positive regulation of signal transduction GO:0009967 223 0.242
Yeast
purine nucleoside catabolic process GO:0006152 112 0.236
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.231
guanosine containing compound metabolic process GO:1901068 74 0.229
purine nucleoside triphosphate catabolic process GO:0009146 108 0.229
centrosome organization GO:0051297 163 0.223
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.216
catabolic process GO:0009056 409 0.213
endocytosis GO:0006897 310 0.213
columnar cuboidal epithelial cell development GO:0002066 249 0.212
embryo development ending in birth or egg hatching GO:0009792 152 0.202
macromolecular complex assembly GO:0065003 256 0.201
Yeast
microtubule polymerization or depolymerization GO:0031109 39 0.195
spermatid differentiation GO:0048515 114 0.192
positive regulation of cell projection organization GO:0031346 29 0.188
cellular component assembly involved in morphogenesis GO:0010927 151 0.184
microtubule organizing center organization GO:0031023 168 0.179
embryonic morphogenesis GO:0048598 206 0.179
regulation of rho protein signal transduction GO:0035023 20 0.179
purine ribonucleoside metabolic process GO:0046128 127 0.179
regulation of growth GO:0040008 233 0.178
regulation of actin filament based process GO:0032970 42 0.175
regulation of cell projection organization GO:0031344 92 0.172
protein localization GO:0008104 284 0.171
Yeast
proteolysis GO:0006508 192 0.171
oocyte microtubule cytoskeleton organization GO:0016325 35 0.171
guanosine containing compound catabolic process GO:1901069 74 0.170
wing disc morphogenesis GO:0007472 344 0.168
lateral inhibition GO:0046331 206 0.161
cytokinesis GO:0000910 90 0.161
Yeast
purine nucleoside triphosphate metabolic process GO:0009144 119 0.160
positive regulation of cellular component organization GO:0051130 156 0.159
muscle cell differentiation GO:0042692 103 0.158
negative regulation of cell communication GO:0010648 223 0.158
centrosome cycle GO:0007098 137 0.158
regulation of cell development GO:0060284 215 0.157
positive regulation of macromolecule metabolic process GO:0010604 405 0.155
Yeast
regulation of response to stress GO:0080134 200 0.153
regulation of actin cytoskeleton organization GO:0032956 42 0.150
positive regulation of nucleotide metabolic process GO:0045981 55 0.150
regulation of cell cycle GO:0051726 291 0.150
Yeast
cell cell signaling involved in cell fate commitment GO:0045168 210 0.149
nucleoside catabolic process GO:0009164 112 0.149
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.148
nucleoside triphosphate metabolic process GO:0009141 120 0.147
regulation of filopodium assembly GO:0051489 24 0.146
nucleotide catabolic process GO:0009166 109 0.144
regulation of gtpase activity GO:0043087 44 0.141
actomyosin structure organization GO:0031032 56 0.141
purine ribonucleotide catabolic process GO:0009154 109 0.139
myotube differentiation GO:0014902 46 0.139
neurological system process GO:0050877 358 0.138
regulation of cell differentiation GO:0045595 302 0.135
cellular catabolic process GO:0044248 372 0.133
homeostatic process GO:0042592 199 0.130
purine nucleotide catabolic process GO:0006195 109 0.130
regulation of intracellular signal transduction GO:1902531 236 0.128
Yeast
ribonucleoside catabolic process GO:0042454 112 0.128
rho protein signal transduction GO:0007266 14 0.126
actin polymerization or depolymerization GO:0008154 31 0.125
synaptic vesicle transport GO:0048489 50 0.125
regulation of anatomical structure size GO:0090066 163 0.123
ras protein signal transduction GO:0007265 88 0.118
striated muscle cell differentiation GO:0051146 90 0.118
regulation of neuron differentiation GO:0045664 103 0.116
cellular macromolecular complex assembly GO:0034622 153 0.116
Yeast
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.114
protein complex biogenesis GO:0070271 201 0.114
negative regulation of response to stimulus GO:0048585 258 0.114
establishment or maintenance of cell polarity GO:0007163 167 0.113
Yeast
regulation of actin filament length GO:0030832 27 0.111
nucleobase containing small molecule metabolic process GO:0055086 174 0.111
regulation of hydrolase activity GO:0051336 97 0.110
regulation of anatomical structure morphogenesis GO:0022603 242 0.110
regulation of catabolic process GO:0009894 170 0.109
imaginal disc derived appendage development GO:0048737 399 0.107
organic substance catabolic process GO:1901575 308 0.106
positive regulation of actin filament polymerization GO:0030838 11 0.106
regulation of small gtpase mediated signal transduction GO:0051056 93 0.106
muscle structure development GO:0061061 224 0.105
organophosphate metabolic process GO:0019637 195 0.105
cellular response to nutrient levels GO:0031669 62 0.105
positive regulation of filopodium assembly GO:0051491 15 0.102
meiotic cell cycle process GO:1903046 132 0.102
spindle organization GO:0007051 253 0.101
regulation of rho gtpase activity GO:0032319 20 0.100
purine nucleotide metabolic process GO:0006163 146 0.100
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.100
carbohydrate derivative metabolic process GO:1901135 217 0.100
adult behavior GO:0030534 137 0.099
negative regulation of protein complex disassembly GO:0043242 23 0.098
ribonucleoside metabolic process GO:0009119 127 0.095
nucleotide metabolic process GO:0009117 161 0.095
cytoplasm organization GO:0007028 64 0.093
positive regulation of cytoskeleton organization GO:0051495 21 0.092
regulation of nucleotide catabolic process GO:0030811 48 0.091
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.090
organic cyclic compound catabolic process GO:1901361 168 0.090
purine containing compound metabolic process GO:0072521 155 0.088
positive regulation of developmental process GO:0051094 143 0.087
regulation of catalytic activity GO:0050790 185 0.087
Yeast
regulation of ras gtpase activity GO:0032318 38 0.085
regulation of cell morphogenesis GO:0022604 163 0.085
regulation of protein complex assembly GO:0043254 42 0.085
positive regulation of catalytic activity GO:0043085 118 0.085
Yeast
glycosyl compound metabolic process GO:1901657 127 0.085
ribonucleotide metabolic process GO:0009259 145 0.083
epithelium migration GO:0090132 148 0.083
gtp catabolic process GO:0006184 72 0.083
negative regulation of synapse assembly GO:0051964 39 0.082
sensory perception of chemical stimulus GO:0007606 116 0.081
ribose phosphate metabolic process GO:0019693 145 0.081
regulation of microtubule cytoskeleton organization GO:0070507 41 0.080
cellular component disassembly GO:0022411 46 0.080
developmental growth GO:0048589 280 0.079
cell migration GO:0016477 238 0.079
positive regulation of signaling GO:0023056 243 0.079
Yeast
regulation of actin polymerization or depolymerization GO:0008064 27 0.078
gtp metabolic process GO:0046039 72 0.077
establishment of organelle localization GO:0051656 122 0.076
metal ion transport GO:0030001 74 0.075
glycosyl compound catabolic process GO:1901658 112 0.074
regulation of cell shape GO:0008360 113 0.074
ribonucleoside triphosphate catabolic process GO:0009203 108 0.073
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.073
small gtpase mediated signal transduction GO:0007264 88 0.072
regulation of neurogenesis GO:0050767 158 0.072
regulation of protein metabolic process GO:0051246 256 0.072
Yeast
chromosome organization GO:0051276 360 0.071
Yeast
positive regulation of catabolic process GO:0009896 105 0.071
hemocyte migration GO:0035099 19 0.071
epithelial cell migration GO:0010631 148 0.070
body morphogenesis GO:0010171 2 0.068
positive regulation of nervous system development GO:0051962 69 0.068
protein complex assembly GO:0006461 200 0.067
purine ribonucleotide metabolic process GO:0009150 145 0.067
positive regulation of gene expression GO:0010628 290 0.067
leg disc morphogenesis GO:0007478 80 0.067
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.066
lamellipodium assembly GO:0030032 21 0.066
regulation of actin filament polymerization GO:0030833 25 0.066
regulation of ras protein signal transduction GO:0046578 93 0.064
epithelial cell differentiation GO:0030855 322 0.063
nucleus localization GO:0051647 34 0.063
nucleoside phosphate metabolic process GO:0006753 162 0.062
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.062
cellular nitrogen compound catabolic process GO:0044270 165 0.061
intracellular signal transduction GO:0035556 300 0.061
Yeast
neurotransmitter transport GO:0006836 37 0.060
death GO:0016265 284 0.060
Yeast
single fertilization GO:0007338 24 0.059
epithelial cell development GO:0002064 274 0.058
chromosome segregation GO:0007059 157 0.058
cellular protein complex assembly GO:0043623 71 0.058
regulation of lamellipodium organization GO:1902743 15 0.058
nucleoside phosphate catabolic process GO:1901292 110 0.057
actin filament bundle assembly GO:0051017 26 0.057
regulation of cell death GO:0010941 173 0.057
Yeast
axonogenesis GO:0007409 290 0.056
peptide metabolic process GO:0006518 80 0.055
protein polymerization GO:0051258 42 0.055
response to nutrient levels GO:0031667 114 0.053
organelle assembly GO:0070925 198 0.053
Yeast
regulation of localization GO:0032879 275 0.052
Yeast
positive regulation of cell communication GO:0010647 250 0.052
Yeast
male gamete generation GO:0048232 201 0.052
aromatic compound catabolic process GO:0019439 166 0.052
positive regulation of multicellular organismal process GO:0051240 143 0.051
imaginal disc fusion GO:0046528 19 0.051
positive regulation of ras gtpase activity GO:0032320 36 0.050
purine containing compound catabolic process GO:0072523 112 0.050
cell growth GO:0016049 108 0.049
Yeast
regulation of wnt signaling pathway GO:0030111 68 0.049
response to organic substance GO:0010033 284 0.049
Yeast
regulation of neuron projection development GO:0010975 69 0.049
morphogenesis of embryonic epithelium GO:0016331 94 0.048
ribonucleotide catabolic process GO:0009261 109 0.048
positive regulation of cellular biosynthetic process GO:0031328 316 0.048
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.048
cortical cytoskeleton organization GO:0030865 29 0.048
regulation of protein polymerization GO:0032271 28 0.048
regulation of organelle organization GO:0033043 196 0.048
Yeast
negative regulation of multicellular organismal process GO:0051241 142 0.047
nucleoside triphosphate catabolic process GO:0009143 108 0.047
negative regulation of microtubule depolymerization GO:0007026 21 0.046
spindle assembly GO:0051225 80 0.046
organophosphate catabolic process GO:0046434 112 0.046
chaeta development GO:0022416 97 0.046
stress fiber assembly GO:0043149 6 0.045
positive regulation of cell differentiation GO:0045597 64 0.044
regulation of microtubule based process GO:0032886 49 0.044
actin filament polymerization GO:0030041 27 0.043
negative regulation of cellular component organization GO:0051129 108 0.043
circulatory system development GO:0072359 82 0.042
regulation of nucleotide metabolic process GO:0006140 62 0.042
eggshell formation GO:0030703 105 0.042
stress activated protein kinase signaling cascade GO:0031098 55 0.041
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.040
blastoderm segmentation GO:0007350 159 0.040
regulation of cellular catabolic process GO:0031329 157 0.040
semaphorin plexin signaling pathway GO:0071526 4 0.040
microtubule based movement GO:0007018 51 0.039
regulation of cellular response to stress GO:0080135 89 0.039
chemical homeostasis GO:0048878 92 0.039
appendage morphogenesis GO:0035107 397 0.038
negative regulation of signaling GO:0023057 219 0.038
autophagy GO:0006914 108 0.038
organelle localization GO:0051640 148 0.038
response to endogenous stimulus GO:0009719 119 0.038
regulation of microtubule depolymerization GO:0031114 24 0.038
positive regulation of hydrolase activity GO:0051345 78 0.037
imaginal disc derived wing hair site selection GO:0035320 4 0.037
protein depolymerization GO:0051261 31 0.037
imaginal disc derived wing morphogenesis GO:0007476 337 0.037
single organism cellular localization GO:1902580 180 0.037
Yeast
wnt signaling pathway GO:0016055 98 0.036
oocyte development GO:0048599 124 0.036
positive regulation of protein complex assembly GO:0031334 22 0.036
response to wounding GO:0009611 94 0.036
heterocycle catabolic process GO:0046700 166 0.035
cytoskeleton dependent intracellular transport GO:0030705 44 0.035
regulation of multi organism process GO:0043900 131 0.035
cell proliferation GO:0008283 299 0.035
regulation of phosphorus metabolic process GO:0051174 210 0.034
Yeast
regulation of gtp catabolic process GO:0033124 44 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.034
microtubule based transport GO:0010970 42 0.034
meiotic cell cycle GO:0051321 171 0.034
negative regulation of organelle organization GO:0010639 56 0.034
protein catabolic process GO:0030163 101 0.034
establishment of proximal distal cell polarity GO:0022606 4 0.034
establishment of nucleus localization GO:0040023 26 0.034
ribonucleoside triphosphate metabolic process GO:0009199 119 0.034
organonitrogen compound catabolic process GO:1901565 128 0.033
stem cell division GO:0017145 69 0.033
morphogenesis of an epithelium GO:0002009 276 0.033
nuclear migration GO:0007097 20 0.033
cell division GO:0051301 248 0.033
Yeast
regulation of purine nucleotide metabolic process GO:1900542 62 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.032
adult locomotory behavior GO:0008344 76 0.032
cellularization GO:0007349 90 0.032
calcium ion transport GO:0006816 24 0.032
regulation of phosphate metabolic process GO:0019220 210 0.032
Yeast
positive regulation of rho gtpase activity GO:0032321 19 0.031
regionalization GO:0003002 416 0.031
positive regulation of rac gtpase activity GO:0032855 8 0.031
muscle attachment GO:0016203 36 0.031
localization of cell GO:0051674 257 0.031
reproductive system development GO:0061458 74 0.030
post embryonic appendage morphogenesis GO:0035120 385 0.030
cellular response to external stimulus GO:0071496 66 0.030
stress activated mapk cascade GO:0051403 52 0.030
regulation of developmental growth GO:0048638 174 0.030
negative regulation of developmental process GO:0051093 201 0.030
cellular amide metabolic process GO:0043603 80 0.030
microtubule depolymerization GO:0007019 25 0.029
cell death GO:0008219 279 0.029
Yeast
cell projection assembly GO:0030031 94 0.029
nucleus organization GO:0006997 45 0.029
axon midline choice point recognition GO:0016199 26 0.029
cardiovascular system development GO:0072358 82 0.028
negative regulation of signal transduction GO:0009968 206 0.028
positive regulation of cell development GO:0010720 61 0.028
sperm individualization GO:0007291 48 0.028
positive regulation of protein polymerization GO:0032273 14 0.028
cation transport GO:0006812 110 0.027
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.027
regulation of molecular function GO:0065009 217 0.027
Yeast
spermatid development GO:0007286 98 0.027
modification dependent protein catabolic process GO:0019941 78 0.027
single organismal cell cell adhesion GO:0016337 45 0.027
membrane invagination GO:0010324 11 0.026
regulation of nurse cell apoptotic process GO:0045477 9 0.026
positive regulation of intracellular signal transduction GO:1902533 116 0.026
Yeast
protein processing GO:0016485 68 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.026
regulation of mitotic cell cycle GO:0007346 190 0.026
Yeast
response to extracellular stimulus GO:0009991 116 0.026
cuticle pattern formation GO:0035017 27 0.026
biological adhesion GO:0022610 138 0.026
positive regulation of organelle organization GO:0010638 65 0.025
response to abiotic stimulus GO:0009628 341 0.025
Yeast
cellular protein localization GO:0034613 160 0.025
Yeast
regulation of purine nucleotide catabolic process GO:0033121 48 0.025
negative regulation of growth GO:0045926 84 0.025
positive regulation of gtpase activity GO:0043547 43 0.025
single organism catabolic process GO:0044712 228 0.025
rna localization GO:0006403 115 0.025
cellular amine metabolic process GO:0044106 12 0.025
protein modification process GO:0036211 438 0.025
Yeast
positive regulation of phosphate metabolic process GO:0045937 139 0.024
Yeast
response to light stimulus GO:0009416 124 0.024
regulation of autophagy GO:0010506 62 0.024
regulation of cellular component movement GO:0051270 42 0.024
divalent inorganic cation transport GO:0072511 30 0.024
exocytosis GO:0006887 28 0.024
axon development GO:0061564 297 0.023
positive regulation of synapse assembly GO:0051965 29 0.023
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.023
tissue morphogenesis GO:0048729 297 0.023
nucleobase containing compound catabolic process GO:0034655 165 0.023
wound healing GO:0042060 75 0.023
telomere maintenance GO:0000723 21 0.023
positive regulation of dendrite development GO:1900006 9 0.023
ubiquitin dependent protein catabolic process GO:0006511 78 0.023
cytokinetic cell separation GO:0000920 1 0.023
Yeast
actin filament based movement GO:0030048 26 0.023
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 8 0.022
positive regulation of cell motility GO:2000147 3 0.022
chorion containing eggshell formation GO:0007304 105 0.022
adherens junction organization GO:0034332 27 0.022
imaginal disc derived appendage morphogenesis GO:0035114 395 0.022
ovarian follicle cell migration GO:0007297 121 0.022
sarcomere organization GO:0045214 26 0.022
jnk cascade GO:0007254 50 0.022
meiosis i GO:0007127 59 0.022
regulation of cellular component size GO:0032535 98 0.022
positive regulation of dendrite morphogenesis GO:0050775 9 0.022
negative regulation of nervous system development GO:0051961 92 0.021
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.021
regulation of response to external stimulus GO:0032101 115 0.021
pronuclear migration GO:0035046 4 0.021
apoptotic cell clearance GO:0043277 14 0.021
cell motility GO:0048870 251 0.021
negative regulation of cellular metabolic process GO:0031324 382 0.021
carbohydrate derivative catabolic process GO:1901136 118 0.021
dorsal appendage formation GO:0046843 47 0.020
positive regulation of cell migration GO:0030335 2 0.020
positive regulation of jun kinase activity GO:0043507 4 0.020
pole plasm assembly GO:0007315 61 0.020
cellular macromolecule catabolic process GO:0044265 136 0.020
positive regulation of phosphorus metabolic process GO:0010562 139 0.020
Yeast
negative regulation of cytoskeleton organization GO:0051494 30 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.020
positive regulation of protein metabolic process GO:0051247 128 0.020
Yeast
positive regulation of rna biosynthetic process GO:1902680 266 0.020
syncytium formation GO:0006949 43 0.020
meiotic cytokinesis GO:0033206 33 0.020
membrane tubulation GO:0097320 4 0.020
receptor clustering GO:0043113 3 0.020
oocyte differentiation GO:0009994 145 0.019
hemopoiesis GO:0030097 46 0.019
protein complex localization GO:0031503 4 0.019
negative regulation of molecular function GO:0044092 51 0.019
regulation of nucleoside metabolic process GO:0009118 50 0.019
endosomal transport GO:0016197 44 0.019
establishment of mitochondrion localization GO:0051654 7 0.019
embryonic pattern specification GO:0009880 174 0.019
posttranscriptional regulation of gene expression GO:0010608 145 0.018
establishment of synaptic vesicle localization GO:0097480 50 0.018
cell type specific apoptotic process GO:0097285 38 0.018
ribonucleoside monophosphate catabolic process GO:0009158 39 0.018
imaginal disc derived leg morphogenesis GO:0007480 80 0.018
positive regulation of rna metabolic process GO:0051254 271 0.018
cell adhesion GO:0007155 136 0.018
sister chromatid segregation GO:0000819 92 0.018
regulation of locomotion GO:0040012 42 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
Yeast
regulation of cellular ketone metabolic process GO:0010565 3 0.018
leg disc development GO:0035218 92 0.018
eye photoreceptor cell development GO:0042462 81 0.018
dorsal closure spreading of leading edge cells GO:0007395 4 0.018
negative regulation of response to external stimulus GO:0032102 22 0.017
tissue migration GO:0090130 155 0.017
response to biotic stimulus GO:0009607 294 0.017
determination of adult lifespan GO:0008340 137 0.017
regulation of peptidase activity GO:0052547 39 0.017
amine metabolic process GO:0009308 12 0.017
establishment of monopolar cell polarity GO:0061162 15 0.017
mesenchymal cell differentiation GO:0048762 1 0.017
antimicrobial humoral response GO:0019730 99 0.017
developmental maturation GO:0021700 172 0.017
regulation of cellular amino acid metabolic process GO:0006521 0 0.017
eye morphogenesis GO:0048592 260 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
collateral sprouting GO:0048668 3 0.017
apoptotic signaling pathway GO:0097190 27 0.016
regulation of innate immune response GO:0045088 71 0.016
immune system development GO:0002520 57 0.016
membrane protein proteolysis GO:0033619 6 0.016
embryonic organ development GO:0048568 50 0.016
positive regulation of peptidase activity GO:0010952 29 0.016
salivary gland development GO:0007431 162 0.016
regulation of stress activated mapk cascade GO:0032872 41 0.016
programmed cell death GO:0012501 257 0.016
Yeast
neuronal stem cell division GO:0036445 35 0.016
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.015
spindle assembly involved in mitosis GO:0090307 50 0.015
mitotic nuclear division GO:0007067 213 0.015
Yeast
secretion GO:0046903 109 0.015
organic substance transport GO:0071702 257 0.015
Yeast
lamellipodium organization GO:0097581 21 0.015
macromolecular complex disassembly GO:0032984 37 0.015
anterior posterior axis specification embryo GO:0008595 103 0.015
defense response GO:0006952 300 0.015
regulation of cell growth GO:0001558 43 0.015
multicellular organismal homeostasis GO:0048871 41 0.015
detection of light stimulus GO:0009583 58 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.015
regulation of cell projection assembly GO:0060491 30 0.015
germ band shortening GO:0007390 19 0.015
skeletal muscle adaptation GO:0043501 1 0.015
negative regulation of catalytic activity GO:0043086 42 0.015
regulation of endopeptidase activity GO:0052548 36 0.015
open tracheal system development GO:0007424 204 0.015
arp2 3 complex mediated actin nucleation GO:0034314 3 0.014
regulation of stress fiber assembly GO:0051492 6 0.014
single organism nuclear import GO:1902593 51 0.014
Yeast
retina development in camera type eye GO:0060041 4 0.014
regulation of myoblast fusion GO:1901739 6 0.014
dorsal closure GO:0007391 79 0.014
regulation of photoreceptor cell differentiation GO:0046532 34 0.014
drinking behavior GO:0042756 2 0.014
positive regulation of lipid storage GO:0010884 4 0.014
protein complex disassembly GO:0043241 36 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
filopodium assembly GO:0046847 33 0.014
carbohydrate metabolic process GO:0005975 82 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.014
stem cell differentiation GO:0048863 117 0.014
regulation of reproductive process GO:2000241 54 0.014
germ line cyst formation GO:0048134 44 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
regulation of notch signaling pathway GO:0008593 100 0.014
fertilization GO:0009566 26 0.014
dorsal ventral pattern formation GO:0009953 133 0.013
maintenance of protein location GO:0045185 28 0.013
pole plasm rna localization GO:0007316 52 0.013
negative regulation of bmp signaling pathway GO:0030514 12 0.013
negative regulation of catabolic process GO:0009895 36 0.013
mesenchymal cell development GO:0014031 1 0.013
planar cell polarity pathway involved in axis elongation GO:0003402 3 0.013
peptidyl threonine phosphorylation GO:0018107 2 0.013
embryonic ectodermal digestive tract morphogenesis GO:0048613 4 0.013
spindle stabilization GO:0043146 14 0.013
regulation of cysteine type endopeptidase activity GO:2000116 27 0.013
acid secretion GO:0046717 1 0.013
connective tissue development GO:0061448 3 0.012
cellular response to heat GO:0034605 24 0.012
Yeast
instar larval development GO:0002168 55 0.012
imaginal disc derived wing hair outgrowth GO:0035318 1 0.012
wnt signaling pathway planar cell polarity pathway GO:0060071 6 0.012
synaptic vesicle exocytosis GO:0016079 16 0.012
cytoskeleton dependent cytokinesis GO:0061640 81 0.012
Yeast
segmentation GO:0035282 207 0.012
single organism carbohydrate metabolic process GO:0044723 72 0.012
meiotic spindle organization GO:0000212 36 0.012
pigmentation GO:0043473 75 0.012
ribosomal large subunit biogenesis GO:0042273 1 0.012
actin nucleation GO:0045010 8 0.012

Pak3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
nervous system disease DOID:863 0 0.013