Drosophila melanogaster

103 known processes

sec15 (Dmel_CG7034)

CG7034 gene product from transcript CG7034-RA

(Aliases: CG7034,dsec15,3R41,Sec15,Sec15p,Dmel\CG7034)

sec15 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to light stimulus GO:0009416 124 0.759
synaptic transmission GO:0007268 288 0.682
cellular catabolic process GO:0044248 372 0.641
response to radiation GO:0009314 155 0.613
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.566
taxis GO:0042330 304 0.534
response to abiotic stimulus GO:0009628 341 0.505
energy taxis GO:0009453 21 0.484
chemotaxis GO:0006935 249 0.462
ovarian follicle cell development GO:0030707 248 0.340
epithelial cell migration GO:0010631 148 0.340
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.317
cell death GO:0008219 279 0.298
intracellular transport GO:0046907 228 0.262
columnar cuboidal epithelial cell development GO:0002066 249 0.253
establishment of localization in cell GO:0051649 402 0.231
single organism intracellular transport GO:1902582 207 0.224
phototaxis GO:0042331 21 0.211
catabolic process GO:0009056 409 0.201
sensory organ morphogenesis GO:0090596 260 0.199
mitotic g2 m transition checkpoint GO:0044818 70 0.189
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.161
organic substance transport GO:0071702 257 0.151
border follicle cell migration GO:0007298 113 0.147
cellular response to ethanol GO:0071361 4 0.140
regulation of multicellular organismal development GO:2000026 414 0.133
defense response to bacterium GO:0042742 178 0.127
glycosyl compound catabolic process GO:1901658 112 0.126
proteolysis GO:0006508 192 0.126
positive regulation of response to stimulus GO:0048584 323 0.125
immune response GO:0006955 246 0.120
immune system process GO:0002376 347 0.116
Mouse
organic cyclic compound catabolic process GO:1901361 168 0.109
ameboidal type cell migration GO:0001667 151 0.109
regulation of cellular catabolic process GO:0031329 157 0.107
response to external biotic stimulus GO:0043207 293 0.107
neuron neuron synaptic transmission GO:0007270 14 0.107
negative regulation of cell communication GO:0010648 223 0.101
development of primary sexual characteristics GO:0045137 50 0.100
regulation of transport GO:0051049 181 0.099
defense response to other organism GO:0098542 225 0.098
sex differentiation GO:0007548 81 0.097
regulation of cellular localization GO:0060341 136 0.096
localization of cell GO:0051674 257 0.094
cell proliferation GO:0008283 299 0.094
macromolecule catabolic process GO:0009057 161 0.092
tissue migration GO:0090130 155 0.091
eye development GO:0001654 323 0.090
protein localization GO:0008104 284 0.084
regulation of apoptotic process GO:0042981 130 0.083
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.082
positive regulation of developmental process GO:0051094 143 0.081
regulation of catabolic process GO:0009894 170 0.081
reproductive structure development GO:0048608 74 0.081
regulation of nervous system development GO:0051960 248 0.080
ovarian follicle cell migration GO:0007297 121 0.079
axon guidance GO:0007411 233 0.078
positive regulation of rna metabolic process GO:0051254 271 0.078
response to oxygen containing compound GO:1901700 200 0.075
epithelial cell differentiation GO:0030855 322 0.074
small molecule metabolic process GO:0044281 305 0.074
regulation of immune system process GO:0002682 176 0.074
ribonucleoside metabolic process GO:0009119 127 0.073
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.073
regulation of molecular function GO:0065009 217 0.071
protein modification by small protein conjugation GO:0032446 79 0.071
regulation of anatomical structure morphogenesis GO:0022603 242 0.071
retinal ganglion cell axon guidance GO:0031290 12 0.067
epithelial cell development GO:0002064 274 0.067
cellular homeostasis GO:0019725 80 0.067
retina development in camera type eye GO:0060041 4 0.066
nucleoside triphosphate metabolic process GO:0009141 120 0.065
single organism catabolic process GO:0044712 228 0.065
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.064
defense response to gram negative bacterium GO:0050829 94 0.061
regulation of vesicle mediated transport GO:0060627 59 0.061
protein transport GO:0015031 155 0.061
microtubule based transport GO:0010970 42 0.060
stem cell differentiation GO:0048863 117 0.060
response to other organism GO:0051707 293 0.059
positive regulation of cellular biosynthetic process GO:0031328 316 0.058
histone modification GO:0016570 106 0.058
gtp catabolic process GO:0006184 72 0.057
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.057
regulation of localization GO:0032879 275 0.056
regulation of cell death GO:0010941 173 0.056
death GO:0016265 284 0.056
response to hexose GO:0009746 3 0.055
vesicle mediated transport GO:0016192 381 0.055
ribonucleoside catabolic process GO:0042454 112 0.054
positive regulation of rab gtpase activity GO:0032851 7 0.053
response to bacterium GO:0009617 198 0.053
establishment of protein localization GO:0045184 163 0.051
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.051
compound eye development GO:0048749 307 0.049
regulation of response to stress GO:0080134 200 0.049
positive regulation of macromolecule metabolic process GO:0010604 405 0.048
positive regulation of rna biosynthetic process GO:1902680 266 0.048
cytoplasmic transport GO:0016482 130 0.048
positive regulation of nucleoside metabolic process GO:0045979 47 0.047
positive regulation of signal transduction GO:0009967 223 0.047
organic substance catabolic process GO:1901575 308 0.047
regulation of neurogenesis GO:0050767 158 0.047
negative regulation of developmental process GO:0051093 201 0.046
protein catabolic process GO:0030163 101 0.046
positive regulation of gene expression GO:0010628 290 0.046
endocytosis GO:0006897 310 0.046
epithelium migration GO:0090132 148 0.045
nucleobase containing small molecule metabolic process GO:0055086 174 0.045
gtp metabolic process GO:0046039 72 0.045
defense response GO:0006952 300 0.045
purine nucleoside triphosphate catabolic process GO:0009146 108 0.045
regulation of purine nucleotide metabolic process GO:1900542 62 0.045
regulation of gtp catabolic process GO:0033124 44 0.044
purine ribonucleoside metabolic process GO:0046128 127 0.044
body morphogenesis GO:0010171 2 0.044
aromatic compound catabolic process GO:0019439 166 0.044
actin filament based process GO:0030029 220 0.044
positive regulation of neurogenesis GO:0050769 41 0.043
positive regulation of gtpase activity GO:0043547 43 0.042
protein modification by small protein conjugation or removal GO:0070647 106 0.042
nucleoside triphosphate catabolic process GO:0009143 108 0.042
purine containing compound catabolic process GO:0072523 112 0.042
intracellular signal transduction GO:0035556 300 0.042
circulatory system development GO:0072359 82 0.041
secondary metabolic process GO:0019748 75 0.041
regulation of protein transport GO:0051223 57 0.040
regulation of cell development GO:0060284 215 0.040
regulation of immune response GO:0050776 118 0.040
g2 dna damage checkpoint GO:0031572 69 0.039
neuron projection guidance GO:0097485 241 0.039
eye photoreceptor cell differentiation GO:0001754 145 0.038
response to monosaccharide GO:0034284 4 0.038
chemical homeostasis GO:0048878 92 0.038
ubiquitin dependent protein catabolic process GO:0006511 78 0.038
positive regulation of cell communication GO:0010647 250 0.038
ras protein signal transduction GO:0007265 88 0.038
mitotic sister chromatid cohesion GO:0007064 6 0.037
cell motility GO:0048870 251 0.037
purine containing compound metabolic process GO:0072521 155 0.037
positive regulation of molecular function GO:0044093 136 0.036
transcription from rna polymerase ii promoter GO:0006366 368 0.036
protein modification process GO:0036211 438 0.036
purine nucleotide metabolic process GO:0006163 146 0.036
regulation of rab gtpase activity GO:0032313 7 0.035
regulation of catalytic activity GO:0050790 185 0.035
autophagy GO:0006914 108 0.035
apoptotic process GO:0006915 159 0.034
regulation of cell differentiation GO:0045595 302 0.034
homeostatic process GO:0042592 199 0.034
Mouse
response to glucose GO:0009749 2 0.033
positive regulation of biosynthetic process GO:0009891 316 0.033
programmed cell death GO:0012501 257 0.033
modification dependent macromolecule catabolic process GO:0043632 79 0.032
cell fate determination GO:0001709 91 0.032
regulation of defense response GO:0031347 102 0.032
guanosine containing compound metabolic process GO:1901068 74 0.032
regulation of intracellular signal transduction GO:1902531 236 0.031
stem cell proliferation GO:0072089 88 0.031
protein ubiquitination GO:0016567 70 0.030
connective tissue development GO:0061448 3 0.030
cellular nitrogen compound catabolic process GO:0044270 165 0.029
regulation of cellular amine metabolic process GO:0033238 3 0.029
guanosine containing compound catabolic process GO:1901069 74 0.029
positive regulation of nucleotide metabolic process GO:0045981 55 0.029
positive regulation of phosphorus metabolic process GO:0010562 139 0.028
organophosphate catabolic process GO:0046434 112 0.028
nucleoside catabolic process GO:0009164 112 0.028
secretion GO:0046903 109 0.028
muscle structure development GO:0061061 224 0.028
regulation of cell cycle GO:0051726 291 0.028
tripartite regional subdivision GO:0007351 103 0.027
glycosyl compound metabolic process GO:1901657 127 0.027
negative regulation of cell cycle process GO:0010948 109 0.027
positive regulation of cellular catabolic process GO:0031331 95 0.027
phagocytosis GO:0006909 215 0.027
protein secretion GO:0009306 45 0.027
ribose phosphate metabolic process GO:0019693 145 0.027
ribonucleotide catabolic process GO:0009261 109 0.027
positive regulation of catabolic process GO:0009896 105 0.027
positive regulation of nucleic acid templated transcription GO:1903508 266 0.026
purine nucleotide catabolic process GO:0006195 109 0.026
innate immune response GO:0045087 144 0.026
positive regulation of cell death GO:0010942 69 0.026
regulation of cell projection organization GO:0031344 92 0.026
regulation of peptidase activity GO:0052547 39 0.026
regulation of nucleotide metabolic process GO:0006140 62 0.025
ommochrome metabolic process GO:0046152 19 0.025
regulation of cytoskeleton organization GO:0051493 89 0.025
negative regulation of immune system process GO:0002683 50 0.025
regulation of gtpase activity GO:0043087 44 0.025
purine nucleoside triphosphate metabolic process GO:0009144 119 0.024
regulation of phosphate metabolic process GO:0019220 210 0.024
camera type eye development GO:0043010 4 0.024
positive regulation of cellular component organization GO:0051130 156 0.024
organonitrogen compound metabolic process GO:1901564 318 0.024
interspecies interaction between organisms GO:0044419 16 0.024
cation transport GO:0006812 110 0.024
positive regulation of phosphate metabolic process GO:0045937 139 0.023
regulation of cell proliferation GO:0042127 163 0.023
nucleoside phosphate catabolic process GO:1901292 110 0.023
tube morphogenesis GO:0035239 191 0.023
cellular ketone metabolic process GO:0042180 24 0.023
regulation of proteolysis GO:0030162 87 0.023
regulation of growth GO:0040008 233 0.023
positive regulation of nervous system development GO:0051962 69 0.023
positive regulation of multicellular organismal process GO:0051240 143 0.023
positive regulation of gtp catabolic process GO:0033126 43 0.022
negative regulation of nucleic acid templated transcription GO:1903507 240 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.022
purine nucleoside metabolic process GO:0042278 127 0.022
establishment of mitochondrion localization GO:0051654 7 0.022
axonogenesis GO:0007409 290 0.022
regulation of nucleoside metabolic process GO:0009118 50 0.022
positive regulation of signaling GO:0023056 243 0.022
regulation of endocytosis GO:0030100 37 0.022
reproductive system development GO:0061458 74 0.021
heart development GO:0007507 82 0.021
response to inorganic substance GO:0010035 44 0.021
establishment of rna localization GO:0051236 47 0.021
mrna transport GO:0051028 15 0.021
secretion by cell GO:0032940 101 0.021
mitotic cell cycle checkpoint GO:0007093 88 0.021
genitalia development GO:0048806 26 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
regulation of protein localization GO:0032880 76 0.021
positive regulation of catalytic activity GO:0043085 118 0.020
nucleotide catabolic process GO:0009166 109 0.020
nitrogen compound transport GO:0071705 85 0.020
positive regulation of protein catabolic process GO:0045732 34 0.020
nucleoside metabolic process GO:0009116 127 0.020
actin cytoskeleton organization GO:0030036 206 0.020
regulation of hormone levels GO:0010817 40 0.020
regulation of programmed cell death GO:0043067 152 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
positive regulation of cell growth GO:0030307 19 0.020
intracellular mrna localization GO:0008298 66 0.020
regulation of epithelial cell proliferation GO:0050678 4 0.019
digestive tract development GO:0048565 149 0.019
limb development GO:0060173 1 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.019
positive regulation of intracellular signal transduction GO:1902533 116 0.019
tissue morphogenesis GO:0048729 297 0.019
organophosphate metabolic process GO:0019637 195 0.019
meiotic nuclear division GO:0007126 151 0.019
hemopoiesis GO:0030097 46 0.019
Mouse
regulation of mitotic cell cycle phase transition GO:1901990 130 0.019
positive regulation of nucleotide catabolic process GO:0030813 46 0.019
modification dependent protein catabolic process GO:0019941 78 0.019
cell cycle dna replication GO:0044786 23 0.019
compound eye morphogenesis GO:0001745 249 0.019
golgi vesicle transport GO:0048193 27 0.018
sister chromatid cohesion GO:0007062 18 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.018
receptor mediated endocytosis GO:0006898 21 0.018
regulation of ras gtpase activity GO:0032318 38 0.018
positive regulation of hydrolase activity GO:0051345 78 0.018
heterocycle catabolic process GO:0046700 166 0.018
organonitrogen compound catabolic process GO:1901565 128 0.018
cellular protein modification process GO:0006464 438 0.018
axon development GO:0061564 297 0.017
negative regulation of gene expression GO:0010629 387 0.017
photoreceptor cell differentiation GO:0046530 170 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
oxoacid metabolic process GO:0043436 103 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.017
negative regulation of response to stimulus GO:0048585 258 0.017
oviposition GO:0018991 19 0.017
mitotic sister chromatid segregation GO:0000070 87 0.017
regulation of nucleotide catabolic process GO:0030811 48 0.017
cellular ion homeostasis GO:0006873 39 0.017
nucleobase containing compound transport GO:0015931 56 0.017
cellular component disassembly GO:0022411 46 0.017
gene silencing by rna GO:0031047 57 0.016
positive regulation of programmed cell death GO:0043068 62 0.016
rab protein signal transduction GO:0032482 6 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
gonad development GO:0008406 50 0.016
rna processing GO:0006396 147 0.016
positive regulation of cell differentiation GO:0045597 64 0.016
organic acid metabolic process GO:0006082 103 0.016
response to biotic stimulus GO:0009607 294 0.016
membrane organization GO:0061024 112 0.015
positive regulation of cell migration GO:0030335 2 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.015
nucleocytoplasmic transport GO:0006913 72 0.015
regulation of neuron differentiation GO:0045664 103 0.015
regulation of intracellular protein transport GO:0033157 46 0.015
digestive tract morphogenesis GO:0048546 127 0.015
regulation of establishment of protein localization GO:0070201 61 0.015
regulation of purine nucleotide catabolic process GO:0033121 48 0.015
positive regulation of cell proliferation GO:0008284 47 0.014
cellular response to oxygen containing compound GO:1901701 79 0.014
hindgut morphogenesis GO:0007442 58 0.014
cardiocyte differentiation GO:0035051 29 0.014
male gamete generation GO:0048232 201 0.014
response to decreased oxygen levels GO:0036293 58 0.014
purine ribonucleotide catabolic process GO:0009154 109 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
cellular macromolecule catabolic process GO:0044265 136 0.014
embryonic organ development GO:0048568 50 0.014
negative regulation of molecular function GO:0044092 51 0.014
regulation of neuron projection development GO:0010975 69 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
mitotic dna damage checkpoint GO:0044773 74 0.014
lipid localization GO:0010876 54 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
anterior posterior pattern specification GO:0009952 136 0.014
regulation of locomotion GO:0040012 42 0.014
intracellular protein transport GO:0006886 104 0.014
dna endoreduplication GO:0042023 22 0.014
positive regulation of transport GO:0051050 92 0.014
regulation of cell size GO:0008361 63 0.014
regulation of autophagy GO:0010506 62 0.014
purine nucleoside catabolic process GO:0006152 112 0.014
negative regulation of signaling GO:0023057 219 0.014
regulation of intracellular transport GO:0032386 64 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
protein depolymerization GO:0051261 31 0.013
positive regulation of cellular component biogenesis GO:0044089 80 0.013
regulation of organ morphogenesis GO:2000027 78 0.013
regulation of dendrite development GO:0050773 37 0.013
activation of ras gtpase activity GO:0032856 6 0.013
regulation of establishment of protein localization to plasma membrane GO:0090003 7 0.013
cuticle development GO:0042335 86 0.013
regulation of system process GO:0044057 36 0.013
cellular protein catabolic process GO:0044257 83 0.013
posttranscriptional gene silencing by rna GO:0035194 45 0.013
regulation of small gtpase mediated signal transduction GO:0051056 93 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
cell adhesion GO:0007155 136 0.013
internal peptidyl lysine acetylation GO:0018393 38 0.013
multicellular organismal aging GO:0010259 140 0.012
cellular amine metabolic process GO:0044106 12 0.012
organelle localization GO:0051640 148 0.012
monocarboxylic acid transport GO:0015718 3 0.012
phosphorylation GO:0016310 294 0.012
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.012
cellular macromolecule localization GO:0070727 220 0.012
synapse organization GO:0050808 196 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
regulation of receptor mediated endocytosis GO:0048259 9 0.012
stem cell development GO:0048864 79 0.012
response to uv GO:0009411 24 0.012
central nervous system development GO:0007417 201 0.012
positive regulation of synapse assembly GO:0051965 29 0.012
outflow tract morphogenesis GO:0003151 4 0.012
establishment of organelle localization GO:0051656 122 0.012
eye morphogenesis GO:0048592 260 0.012
spindle organization GO:0007051 253 0.012
cellular response to radiation GO:0071478 52 0.012
chorion containing eggshell formation GO:0007304 105 0.011
response to ionizing radiation GO:0010212 32 0.011
cellular response to hexose stimulus GO:0071331 1 0.011
rac protein signal transduction GO:0016601 3 0.011
regulation of golgi to plasma membrane protein transport GO:0042996 6 0.011
spermatid development GO:0007286 98 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
response to nutrient levels GO:0031667 114 0.011
regulation of response to external stimulus GO:0032101 115 0.011
amine metabolic process GO:0009308 12 0.011
regulation of protein catabolic process GO:0042176 55 0.011
gene silencing GO:0016458 138 0.011
blastoderm segmentation GO:0007350 159 0.011
determination of dorsal ventral asymmetry GO:0048262 3 0.011
ion transport GO:0006811 145 0.011
multi organism behavior GO:0051705 175 0.011
positive regulation of organelle organization GO:0010638 65 0.011
response to extracellular stimulus GO:0009991 116 0.011
striated muscle cell differentiation GO:0051146 90 0.011
mesenchymal cell development GO:0014031 1 0.011
cardiovascular system development GO:0072358 82 0.011
endomembrane system organization GO:0010256 119 0.011
response to organophosphorus GO:0046683 2 0.011
androgen metabolic process GO:0008209 1 0.011
single organism cellular localization GO:1902580 180 0.011
cell fate specification GO:0001708 71 0.011
neural precursor cell proliferation GO:0061351 75 0.011
negative regulation of cell cycle GO:0045786 116 0.011
negative regulation of cell cycle phase transition GO:1901988 103 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
detection of external stimulus GO:0009581 66 0.011
mrna catabolic process GO:0006402 33 0.011
response to heat GO:0009408 63 0.011
cellular response to monosaccharide stimulus GO:0071326 2 0.010
regulation of cytoplasmic transport GO:1903649 47 0.010
ion transmembrane transport GO:0034220 122 0.010
regulation of phosphatase activity GO:0010921 3 0.010
nucleotide metabolic process GO:0009117 161 0.010
cellular cation homeostasis GO:0030003 38 0.010
developmental programmed cell death GO:0010623 138 0.010
cell cycle checkpoint GO:0000075 95 0.010
purine ribonucleoside catabolic process GO:0046130 112 0.010
regulation of cellular component size GO:0032535 98 0.010
ion homeostasis GO:0050801 55 0.010
regulation of endopeptidase activity GO:0052548 36 0.010
sister chromatid segregation GO:0000819 92 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
reproductive behavior GO:0019098 122 0.010
salivary gland development GO:0007431 162 0.010
regionalization GO:0003002 416 0.010
somatic muscle development GO:0007525 66 0.010
nucleic acid transport GO:0050657 46 0.010
hindgut development GO:0061525 58 0.010
response to sterol GO:0036314 34 0.010
gastrulation GO:0007369 70 0.010

sec15 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.029
disease of cellular proliferation DOID:14566 0 0.029
organ system cancer DOID:0050686 0 0.029
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010