Drosophila melanogaster

209 known processes

Cbl (Dmel_CG7037)

CG7037 gene product from transcript CG7037-RB

(Aliases: CG7037,DCbl,cbl,anon-WO0118547.68,D-cblS,F165,CBL,D-cbl,D-Cbl L,D-cblL,Dv-cbl,CG7043,dCbl,d-cbl,D-Cbl,Dmel\CG7037,Dv-Cbl,Dcbl)

Cbl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
epithelial cell migration GO:0010631 148 0.997
ovarian follicle cell development GO:0030707 248 0.983
chorion containing eggshell formation GO:0007304 105 0.979
columnar cuboidal epithelial cell development GO:0002066 249 0.894
tissue migration GO:0090130 155 0.890
border follicle cell migration GO:0007298 113 0.869
eye photoreceptor cell differentiation GO:0001754 145 0.860
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.778
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.764
eggshell chorion assembly GO:0007306 66 0.759
immune response GO:0006955 246 0.712
Mouse
programmed cell death GO:0012501 257 0.708
Human
epithelial cell development GO:0002064 274 0.686
eye development GO:0001654 323 0.667
cellular ketone metabolic process GO:0042180 24 0.665
respiratory system development GO:0060541 213 0.649
cellular component assembly involved in morphogenesis GO:0010927 151 0.642
eggshell formation GO:0030703 105 0.638
epithelial cell differentiation GO:0030855 322 0.574
erbb signaling pathway GO:0038127 58 0.539
regionalization GO:0003002 416 0.529
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.516
positive regulation of signaling GO:0023056 243 0.501
Human
carboxylic acid metabolic process GO:0019752 92 0.414
myotube cell development GO:0014904 3 0.414
sensory organ morphogenesis GO:0090596 260 0.411
axonogenesis GO:0007409 290 0.408
regulation of protein metabolic process GO:0051246 256 0.403
body morphogenesis GO:0010171 2 0.392
r7 cell differentiation GO:0045466 43 0.385
ameboidal type cell migration GO:0001667 151 0.381
positive regulation of gene expression GO:0010628 290 0.366
regulation of cellular ketone metabolic process GO:0010565 3 0.359
compound eye morphogenesis GO:0001745 249 0.357
death GO:0016265 284 0.353
regulation of intracellular signal transduction GO:1902531 236 0.346
Human
chromosome organization GO:0051276 360 0.345
ovarian follicle cell migration GO:0007297 121 0.338
negative regulation of cellular metabolic process GO:0031324 382 0.331
positive regulation of rna biosynthetic process GO:1902680 266 0.325
regulation of cellular amino acid metabolic process GO:0006521 0 0.299
dorsal appendage formation GO:0046843 47 0.298
protein modification process GO:0036211 438 0.298
regulation of protein tyrosine kinase activity GO:0061097 9 0.297
photoreceptor cell differentiation GO:0046530 170 0.297
central nervous system development GO:0007417 201 0.290
compound eye photoreceptor fate commitment GO:0001752 36 0.290
localization of cell GO:0051674 257 0.282
regulation of programmed cell death GO:0043067 152 0.278
Human
carbohydrate derivative metabolic process GO:1901135 217 0.268
establishment of localization in cell GO:0051649 402 0.266
cell motility GO:0048870 251 0.263
epithelium migration GO:0090132 148 0.261
immune system process GO:0002376 347 0.260
Mouse
reproductive structure development GO:0048608 74 0.250
cell migration GO:0016477 238 0.250
regulation of cellular catabolic process GO:0031329 157 0.248
positive regulation of cell communication GO:0010647 250 0.247
Human
positive regulation of rna metabolic process GO:0051254 271 0.236
tissue morphogenesis GO:0048729 297 0.230
regulation of mitotic cell cycle GO:0007346 190 0.228
homeostatic process GO:0042592 199 0.225
regulation of cellular protein metabolic process GO:0032268 243 0.222
regulation of apoptotic process GO:0042981 130 0.221
Human
embryonic digestive tract development GO:0048566 5 0.219
dorsal ventral axis specification GO:0009950 66 0.218
imaginal disc derived wing morphogenesis GO:0007476 337 0.215
regulation of catalytic activity GO:0050790 185 0.214
compound eye photoreceptor cell differentiation GO:0001751 140 0.209
compound eye development GO:0048749 307 0.205
r7 cell fate commitment GO:0007465 12 0.196
biological adhesion GO:0022610 138 0.191
imaginal disc derived appendage development GO:0048737 399 0.191
macromolecule catabolic process GO:0009057 161 0.186
Human Mouse
dorsal ventral pattern formation GO:0009953 133 0.185
positive regulation of signal transduction GO:0009967 223 0.179
Human
protein ubiquitination GO:0016567 70 0.179
Human
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.178
positive regulation of macromolecule metabolic process GO:0010604 405 0.175
Mouse
mitotic cell cycle phase transition GO:0044772 138 0.172
cell death GO:0008219 279 0.170
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.168
catabolic process GO:0009056 409 0.168
Human Mouse
oocyte dorsal ventral axis specification GO:0007310 34 0.168
positive regulation of cellular protein metabolic process GO:0032270 118 0.157
camera type eye development GO:0043010 4 0.153
axon development GO:0061564 297 0.153
epidermal growth factor receptor signaling pathway GO:0007173 58 0.151
apoptotic process GO:0006915 159 0.149
Human
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.148
positive regulation of biosynthetic process GO:0009891 316 0.147
positive regulation of phosphate metabolic process GO:0045937 139 0.147
imaginal disc derived wing vein specification GO:0007474 48 0.146
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.146
cellular protein modification process GO:0006464 438 0.144
negative regulation of biosynthetic process GO:0009890 277 0.143
regulation of cell death GO:0010941 173 0.143
wing disc morphogenesis GO:0007472 344 0.141
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.140
nuclear import GO:0051170 51 0.135
establishment or maintenance of cell polarity GO:0007163 167 0.134
anterior posterior pattern specification GO:0009952 136 0.134
cellular catabolic process GO:0044248 372 0.133
Human
posttranscriptional gene silencing GO:0016441 46 0.133
nucleocytoplasmic transport GO:0006913 72 0.133
regulation of molecular function GO:0065009 217 0.130
positive regulation of intracellular signal transduction GO:1902533 116 0.130
Human
peptidyl amino acid modification GO:0018193 105 0.130
regulation of cell cycle GO:0051726 291 0.128
regulation of catabolic process GO:0009894 170 0.127
Mouse
negative regulation of gene expression GO:0010629 387 0.127
transcription from rna polymerase ii promoter GO:0006366 368 0.123
protein modification by small protein conjugation or removal GO:0070647 106 0.122
Human
cellular macromolecular complex assembly GO:0034622 153 0.120
appendage morphogenesis GO:0035107 397 0.120
regulation of cellular localization GO:0060341 136 0.119
regulation of epidermal growth factor activated receptor activity GO:0007176 4 0.119
negative regulation of autophagy GO:0010507 16 0.119
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.118
positive regulation of proteolysis GO:0045862 52 0.117
negative regulation of response to stimulus GO:0048585 258 0.117
cellular response to chemical stimulus GO:0070887 199 0.117
positive regulation of hydrolase activity GO:0051345 78 0.115
regulation of cell cycle phase transition GO:1901987 130 0.114
nucleotide metabolic process GO:0009117 161 0.113
tube morphogenesis GO:0035239 191 0.112
developmental maturation GO:0021700 172 0.111
response to organic substance GO:0010033 284 0.111
Rat
head development GO:0060322 135 0.110
positive regulation of transcription dna templated GO:0045893 266 0.110
protein complex assembly GO:0006461 200 0.110
negative regulation of signal transduction GO:0009968 206 0.107
compound eye photoreceptor development GO:0042051 78 0.105
positive regulation of protein metabolic process GO:0051247 128 0.103
Mouse
positive regulation of cellular amine metabolic process GO:0033240 0 0.101
single organismal cell cell adhesion GO:0016337 45 0.100
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.100
protein maturation GO:0051604 71 0.099
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.099
phosphorylation GO:0016310 294 0.096
positive regulation of phosphorus metabolic process GO:0010562 139 0.096
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.096
mapk cascade GO:0000165 107 0.096
Human
growth GO:0040007 359 0.095
cellular protein catabolic process GO:0044257 83 0.094
Human
regulation of ras protein signal transduction GO:0046578 93 0.093
aging GO:0007568 143 0.093
cell maturation GO:0048469 144 0.090
male gamete generation GO:0048232 201 0.090
cellular response to organic substance GO:0071310 132 0.088
eye morphogenesis GO:0048592 260 0.088
blastoderm segmentation GO:0007350 159 0.087
nucleoside triphosphate metabolic process GO:0009141 120 0.086
organic acid metabolic process GO:0006082 103 0.086
modification dependent macromolecule catabolic process GO:0043632 79 0.086
Human
regulation of cellular response to stress GO:0080135 89 0.085
enzyme linked receptor protein signaling pathway GO:0007167 179 0.085
protein catabolic process GO:0030163 101 0.085
Human Mouse
ribonucleoside triphosphate catabolic process GO:0009203 108 0.084
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.083
oxoacid metabolic process GO:0043436 103 0.083
negative regulation of transcription dna templated GO:0045892 237 0.083
spermatogenesis GO:0007283 200 0.081
posttranscriptional regulation of gene expression GO:0010608 145 0.080
negative regulation of signaling GO:0023057 219 0.080
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.080
positive regulation of multicellular organismal process GO:0051240 143 0.080
Mouse
regulation of cell cycle g1 s phase transition GO:1902806 23 0.079
purine nucleotide metabolic process GO:0006163 146 0.077
striated muscle cell differentiation GO:0051146 90 0.076
spindle organization GO:0007051 253 0.076
tube development GO:0035295 244 0.076
embryonic development via the syncytial blastoderm GO:0001700 148 0.076
organelle fission GO:0048285 340 0.075
positive regulation of r7 cell differentiation GO:0045678 7 0.074
actin filament based process GO:0030029 220 0.074
positive regulation of nucleic acid templated transcription GO:1903508 266 0.073
dna metabolic process GO:0006259 227 0.072
single organism cell adhesion GO:0098602 47 0.072
response to oxygen radical GO:0000305 3 0.072
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.070
phosphatidylinositol mediated signaling GO:0048015 4 0.069
Human
cell cycle phase transition GO:0044770 140 0.068
regulation of mitotic cell cycle phase transition GO:1901990 130 0.068
secretion GO:0046903 109 0.065
positive regulation of cellular biosynthetic process GO:0031328 316 0.065
regulation of nucleocytoplasmic transport GO:0046822 35 0.065
positive regulation of cellular catabolic process GO:0031331 95 0.065
organophosphate metabolic process GO:0019637 195 0.064
positive regulation of mapk cascade GO:0043410 63 0.064
axis specification GO:0009798 167 0.063
negative regulation of cell cycle g1 s phase transition GO:1902807 13 0.062
regulation of r7 cell differentiation GO:0045676 15 0.062
organic cyclic compound catabolic process GO:1901361 168 0.062
positive regulation of catabolic process GO:0009896 105 0.061
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.061
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.060
stress activated protein kinase signaling cascade GO:0031098 55 0.060
chemotaxis GO:0006935 249 0.059
intracellular transport GO:0046907 228 0.059
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.058
autophagy GO:0006914 108 0.057
positive regulation of cell adhesion GO:0045785 10 0.057
muscle structure development GO:0061061 224 0.057
regulation of cellular amine metabolic process GO:0033238 3 0.057
small gtpase mediated signal transduction GO:0007264 88 0.057
photoreceptor cell development GO:0042461 96 0.057
organonitrogen compound metabolic process GO:1901564 318 0.056
regulation of cell cycle process GO:0010564 181 0.056
positive regulation of nucleoside metabolic process GO:0045979 47 0.055
stress activated mapk cascade GO:0051403 52 0.055
negative regulation of cell cycle process GO:0010948 109 0.055
organic substance catabolic process GO:1901575 308 0.054
Human Mouse
inositol lipid mediated signaling GO:0048017 4 0.054
Human
small molecule metabolic process GO:0044281 305 0.054
regulation of small gtpase mediated signal transduction GO:0051056 93 0.054
protein modification by small protein conjugation GO:0032446 79 0.053
Human
protein complex biogenesis GO:0070271 201 0.053
neuron projection guidance GO:0097485 241 0.052
regulation of protein kinase activity GO:0045859 51 0.052
proteolysis GO:0006508 192 0.052
Human
cell cycle g1 s phase transition GO:0044843 31 0.052
negative regulation of protein tyrosine kinase activity GO:0061099 5 0.051
single organism cellular localization GO:1902580 180 0.050
anterior posterior axis specification embryo GO:0008595 103 0.050
photoreceptor cell fate commitment GO:0046552 41 0.049
cell fate determination GO:0001709 91 0.049
response to external biotic stimulus GO:0043207 293 0.049
regulation of organ morphogenesis GO:2000027 78 0.048
regulation of hydrolase activity GO:0051336 97 0.048
response to fungus GO:0009620 50 0.048
rna processing GO:0006396 147 0.048
carbohydrate derivative biosynthetic process GO:1901137 85 0.047
muscle cell differentiation GO:0042692 103 0.047
meiotic cell cycle GO:0051321 171 0.047
negative regulation of cell cycle GO:0045786 116 0.046
oocyte development GO:0048599 124 0.046
cell adhesion GO:0007155 136 0.045
regulation of cell morphogenesis GO:0022604 163 0.045
regulation of embryonic development GO:0045995 68 0.045
negative regulation of cell death GO:0060548 81 0.045
Human
regulation of growth GO:0040008 233 0.045
positive regulation of nucleotide metabolic process GO:0045981 55 0.045
torc1 signaling GO:0038202 12 0.045
positive regulation of protein catabolic process GO:0045732 34 0.044
Mouse
eye photoreceptor cell development GO:0042462 81 0.044
regulation of vesicle mediated transport GO:0060627 59 0.044
skeletal muscle fiber development GO:0048741 3 0.043
peptidyl threonine phosphorylation GO:0018107 2 0.043
multicellular organism growth GO:0035264 46 0.043
appendage development GO:0048736 401 0.042
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.042
intrinsic apoptotic signaling pathway GO:0097193 16 0.042
nuclear transport GO:0051169 72 0.042
ribonucleotide biosynthetic process GO:0009260 28 0.042
nucleoside phosphate catabolic process GO:1901292 110 0.041
response to organic cyclic compound GO:0014070 89 0.041
regulation of cell development GO:0060284 215 0.040
segmentation GO:0035282 207 0.039
negative regulation of cell communication GO:0010648 223 0.039
ras protein signal transduction GO:0007265 88 0.039
response to other organism GO:0051707 293 0.039
regulation of protein phosphorylation GO:0001932 64 0.039
adherens junction organization GO:0034332 27 0.038
regulation of neurogenesis GO:0050767 158 0.038
regulation of hormone levels GO:0010817 40 0.038
negative regulation of nucleic acid templated transcription GO:1903507 240 0.038
actin cytoskeleton organization GO:0030036 206 0.038
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.038
synaptic vesicle transport GO:0048489 50 0.038
negative regulation of cell cycle phase transition GO:1901988 103 0.038
regulation of purine nucleotide metabolic process GO:1900542 62 0.038
cell cycle checkpoint GO:0000075 95 0.037
regulation of autophagy GO:0010506 62 0.037
peptidyl tyrosine modification GO:0018212 24 0.037
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.037
single organism biosynthetic process GO:0044711 206 0.037
embryonic pattern specification GO:0009880 174 0.037
striated muscle cell development GO:0055002 50 0.037
regulation of mapk cascade GO:0043408 92 0.036
Human
negative regulation of cell proliferation GO:0008285 69 0.036
Mouse
activation of protein kinase activity GO:0032147 12 0.036
positive regulation of catalytic activity GO:0043085 118 0.035
oocyte differentiation GO:0009994 145 0.035
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.035
regulation of apoptotic signaling pathway GO:2001233 10 0.035
negative regulation of apoptotic process GO:0043066 63 0.035
Human
forebrain development GO:0030900 2 0.035
dorsal ventral axis specification ovarian follicular epithelium GO:0008069 13 0.035
oocyte axis specification GO:0007309 108 0.035
embryonic digestive tract morphogenesis GO:0048557 4 0.034
single organism intracellular transport GO:1902582 207 0.034
g1 s transition of mitotic cell cycle GO:0000082 31 0.034
establishment of organelle localization GO:0051656 122 0.034
secretion by cell GO:0032940 101 0.034
brain development GO:0007420 120 0.034
positive regulation of protein modification process GO:0031401 58 0.034
regulation of transport GO:0051049 181 0.034
negative regulation of cell adhesion GO:0007162 9 0.034
oocyte construction GO:0007308 112 0.033
response to biotic stimulus GO:0009607 294 0.033
cytoplasmic transport GO:0016482 130 0.033
protein phosphorylation GO:0006468 169 0.033
salivary gland cell autophagic cell death GO:0035071 83 0.033
neuron fate commitment GO:0048663 50 0.033
regulation of response to external stimulus GO:0032101 115 0.032
histolysis GO:0007559 102 0.032
mitotic spindle organization GO:0007052 220 0.032
regulation of cell division GO:0051302 72 0.032
regulation of cytoplasmic transport GO:1903649 47 0.032
positive regulation of response to stimulus GO:0048584 323 0.032
Human Mouse
regulation of protein modification process GO:0031399 112 0.031
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.031
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.031
positive regulation of mitotic cell cycle GO:0045931 34 0.031
defense response to fungus GO:0050832 48 0.030
dendrite morphogenesis GO:0048813 199 0.030
reproductive system development GO:0061458 74 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.029
positive regulation of phosphorylation GO:0042327 87 0.029
germarium derived oocyte fate determination GO:0007294 26 0.029
meiosis i GO:0007127 59 0.029
macromolecular complex assembly GO:0065003 256 0.029
head involution GO:0008258 35 0.029
positive regulation of cell cycle process GO:0090068 28 0.029
defense response to gram negative bacterium GO:0050829 94 0.028
cellular amine metabolic process GO:0044106 12 0.028
regulation of translation GO:0006417 56 0.028
lipid metabolic process GO:0006629 121 0.028
response to alcohol GO:0097305 95 0.028
negative regulation of catalytic activity GO:0043086 42 0.027
regulation of nuclear division GO:0051783 58 0.027
hematopoietic or lymphoid organ development GO:0048534 57 0.027
cell fate specification GO:0001708 71 0.027
determination of adult lifespan GO:0008340 137 0.027
positive regulation of photoreceptor cell differentiation GO:0046534 12 0.027
nuclear division GO:0000280 332 0.027
response to ecdysone GO:0035075 34 0.027
regulation of proteolysis GO:0030162 87 0.027
regulation of ras gtpase activity GO:0032318 38 0.027
dendrite development GO:0016358 204 0.027
ribonucleoside catabolic process GO:0042454 112 0.026
positive regulation of apoptotic process GO:0043065 47 0.026
erk1 and erk2 cascade GO:0070371 39 0.026
ribonucleoside triphosphate metabolic process GO:0009199 119 0.026
modification dependent protein catabolic process GO:0019941 78 0.026
Human
axon guidance GO:0007411 233 0.026
response to sterol GO:0036314 34 0.026
cellular response to oxygen containing compound GO:1901701 79 0.026
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.026
regulation of anatomical structure morphogenesis GO:0022603 242 0.026
chromatin modification GO:0016568 147 0.026
developmental growth GO:0048589 280 0.026
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.026
chromatin organization GO:0006325 207 0.026
histoblast morphogenesis GO:0007488 9 0.026
cell aging GO:0007569 2 0.025
regulation of protein catabolic process GO:0042176 55 0.025
Mouse
regulation of phosphorus metabolic process GO:0051174 210 0.025
mrna metabolic process GO:0016071 124 0.025
morphogenesis of a branching structure GO:0001763 45 0.025
protein import GO:0017038 55 0.025
skeletal muscle organ development GO:0060538 48 0.025
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.025
Human
regulation of protein import into nucleus GO:0042306 28 0.025
regulation of nucleoside metabolic process GO:0009118 50 0.025
protein processing GO:0016485 68 0.025
negative regulation of cellular protein metabolic process GO:0032269 85 0.025
mitotic nuclear division GO:0007067 213 0.025
stem cell maintenance GO:0019827 67 0.025
positive regulation of protein transport GO:0051222 37 0.025
heart development GO:0007507 82 0.024
negative regulation of protein metabolic process GO:0051248 85 0.024
response to nitrogen compound GO:1901698 90 0.024
regulation of gtpase activity GO:0043087 44 0.024
negative regulation of programmed cell death GO:0043069 72 0.024
Human
developmental programmed cell death GO:0010623 138 0.024
reactive oxygen species metabolic process GO:0072593 22 0.023
regulation of cellular protein catabolic process GO:1903362 44 0.023
intracellular signal transduction GO:0035556 300 0.023
Human Mouse
response to superoxide GO:0000303 3 0.023
regulation of anatomical structure size GO:0090066 163 0.023
rho protein signal transduction GO:0007266 14 0.023
embryonic morphogenesis GO:0048598 206 0.023
response to oxygen containing compound GO:1901700 200 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.023
Human
response to ketone GO:1901654 34 0.023
ribonucleotide metabolic process GO:0009259 145 0.023
regulation of kinase activity GO:0043549 53 0.023
regulation of cardioblast differentiation GO:0051890 9 0.022
gtp catabolic process GO:0006184 72 0.022
leg disc development GO:0035218 92 0.022
sex differentiation GO:0007548 81 0.022
negative regulation of rna metabolic process GO:0051253 251 0.022
proteasomal protein catabolic process GO:0010498 59 0.022
negative regulation of catabolic process GO:0009895 36 0.022
hematopoietic progenitor cell differentiation GO:0002244 1 0.022
nucleoside phosphate metabolic process GO:0006753 162 0.022
exocrine system development GO:0035272 162 0.022
purine containing compound metabolic process GO:0072521 155 0.022
ribonucleotide catabolic process GO:0009261 109 0.021
cellular macromolecule catabolic process GO:0044265 136 0.021
Human
defense response to other organism GO:0098542 225 0.021
regulation of secretion by cell GO:1903530 39 0.021
autophagic cell death GO:0048102 83 0.021
response to endogenous stimulus GO:0009719 119 0.021
Rat
positive regulation of gtp catabolic process GO:0033126 43 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
regulation of mitosis GO:0007088 56 0.021
cell cell junction organization GO:0045216 55 0.021
regulation of cell growth GO:0001558 43 0.021
divalent metal ion transport GO:0070838 26 0.020
regulation of organelle organization GO:0033043 196 0.020
apoptotic signaling pathway GO:0097190 27 0.020
peptidyl tyrosine phosphorylation GO:0018108 24 0.020
regulation of stress activated mapk cascade GO:0032872 41 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.020
negative regulation of mitotic cell cycle GO:0045930 109 0.020
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.020
purine ribonucleotide metabolic process GO:0009150 145 0.020
ribonucleoside metabolic process GO:0009119 127 0.020
cell division GO:0051301 248 0.019
embryonic axis specification GO:0000578 107 0.019
innate immune response GO:0045087 144 0.019
specification of organ identity GO:0010092 3 0.019
single organism catabolic process GO:0044712 228 0.019
eye photoreceptor cell fate commitment GO:0042706 37 0.019
mitotic sister chromatid segregation GO:0000070 87 0.019
ribose phosphate biosynthetic process GO:0046390 28 0.019
regulation of developmental growth GO:0048638 174 0.019
gland development GO:0048732 191 0.019
regulation of gtp catabolic process GO:0033124 44 0.018
single organism carbohydrate metabolic process GO:0044723 72 0.018
cellular macromolecule localization GO:0070727 220 0.018
regulation of rna splicing GO:0043484 69 0.018
determination of left right symmetry GO:0007368 9 0.018
positive regulation of lipid metabolic process GO:0045834 4 0.018
response to bacterium GO:0009617 198 0.018
regulation of erk1 and erk2 cascade GO:0070372 39 0.018
salivary gland development GO:0007431 162 0.018
rna splicing GO:0008380 83 0.018
organ growth GO:0035265 56 0.018
regulation of cell adhesion GO:0030155 27 0.018
amine metabolic process GO:0009308 12 0.018
regulation of cellular response to oxidative stress GO:1900407 4 0.018
carbohydrate metabolic process GO:0005975 82 0.018
positive regulation of transport GO:0051050 92 0.018
muscle cell development GO:0055001 50 0.018
terminal region determination GO:0007362 25 0.018
regulation of response to stress GO:0080134 200 0.017
cellular response to dna damage stimulus GO:0006974 223 0.017
positive regulation of apoptotic signaling pathway GO:2001235 4 0.017
regulation of nucleotide metabolic process GO:0006140 62 0.017
regulation of secretion GO:0051046 44 0.017
positive regulation of protein phosphorylation GO:0001934 34 0.017
positive regulation of organelle organization GO:0010638 65 0.017
positive regulation of molecular function GO:0044093 136 0.017
regulation of intracellular transport GO:0032386 64 0.017
response to abiotic stimulus GO:0009628 341 0.017
Rat
response to oxidative stress GO:0006979 86 0.017
regulation of immune response GO:0050776 118 0.017
Mouse
regulation of establishment of protein localization GO:0070201 61 0.017
protein localization GO:0008104 284 0.017
open tracheal system development GO:0007424 204 0.017
synaptic vesicle localization GO:0097479 53 0.017
protein transport GO:0015031 155 0.017
immune effector process GO:0002252 98 0.017
regulation of multicellular organismal development GO:2000026 414 0.017
Mouse Worm
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.017
retina development in camera type eye GO:0060041 4 0.016
positive regulation of cell development GO:0010720 61 0.016
rna splicing via transesterification reactions GO:0000375 73 0.016
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.016
defense response to bacterium GO:0042742 178 0.016
purine nucleoside metabolic process GO:0042278 127 0.016
regulation of map kinase activity GO:0043405 17 0.016
Human
wound healing GO:0042060 75 0.016
protein targeting to nucleus GO:0044744 51 0.016
single organism nuclear import GO:1902593 51 0.016
connective tissue development GO:0061448 3 0.016
negative regulation of phosphorus metabolic process GO:0010563 45 0.016
membrane organization GO:0061024 112 0.016
cellular nitrogen compound catabolic process GO:0044270 165 0.015
anterior posterior axis specification GO:0009948 109 0.015
positive regulation of kinase activity GO:0033674 25 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
regulation of protein localization GO:0032880 76 0.015
regulation of behavior GO:0050795 75 0.015
stem cell development GO:0048864 79 0.015
intracellular protein transport GO:0006886 104 0.015
cellular homeostasis GO:0019725 80 0.015
regulation of mrna metabolic process GO:1903311 72 0.015
embryo development ending in birth or egg hatching GO:0009792 152 0.015

Cbl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.030
disease of cellular proliferation DOID:14566 0 0.030
organ system cancer DOID:0050686 0 0.030
breast cancer DOID:1612 0 0.015
thoracic cancer DOID:5093 0 0.015