Drosophila melanogaster

33 known processes

spel1 (Dmel_CG4215)

spellchecker1

(Aliases: BG:DS01068.9,Msh2,CG4215,spel,Dmel\CG4215,SPEL1,spel-1)

spel1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 0.187
catabolic process GO:0009056 409 0.128
Human
regulation of cell cycle process GO:0010564 181 0.118
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.114
negative regulation of gene expression GO:0010629 387 0.089
heterocycle catabolic process GO:0046700 166 0.081
Human
dna conformation change GO:0071103 105 0.075
organic cyclic compound catabolic process GO:1901361 168 0.069
Human
organic substance catabolic process GO:1901575 308 0.068
Human
dna replication GO:0006260 48 0.062
cellular catabolic process GO:0044248 372 0.058
Human
dna metabolic process GO:0006259 227 0.058
response to other organism GO:0051707 293 0.058
chromatin organization GO:0006325 207 0.057
cellular nitrogen compound catabolic process GO:0044270 165 0.057
Human
protein complex biogenesis GO:0070271 201 0.056
response to external biotic stimulus GO:0043207 293 0.056
negative regulation of transcription dna templated GO:0045892 237 0.055
regulation of molecular function GO:0065009 217 0.054
Human
regulation of protein metabolic process GO:0051246 256 0.054
regulation of gene expression epigenetic GO:0040029 128 0.052
cellular macromolecule catabolic process GO:0044265 136 0.049
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.049
organonitrogen compound metabolic process GO:1901564 318 0.049
Human
regulation of cell cycle GO:0051726 291 0.048
negative regulation of gene expression epigenetic GO:0045814 77 0.047
developmental growth GO:0048589 280 0.045
cellular protein modification process GO:0006464 438 0.045
negative regulation of biosynthetic process GO:0009890 277 0.045
regulation of multicellular organismal development GO:2000026 414 0.044
dna repair GO:0006281 54 0.044
nuclear division GO:0000280 332 0.044
mitotic cell cycle phase transition GO:0044772 138 0.044
single organism biosynthetic process GO:0044711 206 0.042
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.041
Human
protein modification process GO:0036211 438 0.041
cell cycle checkpoint GO:0000075 95 0.041
positive regulation of macromolecule metabolic process GO:0010604 405 0.040
negative regulation of rna metabolic process GO:0051253 251 0.040
growth GO:0040007 359 0.039
carbohydrate derivative metabolic process GO:1901135 217 0.039
Human
regulation of catalytic activity GO:0050790 185 0.038
Human
regulation of mitotic cell cycle GO:0007346 190 0.038
cellular response to dna damage stimulus GO:0006974 223 0.036
oxoacid metabolic process GO:0043436 103 0.036
negative regulation of rna biosynthetic process GO:1902679 240 0.036
negative regulation of nucleic acid templated transcription GO:1903507 240 0.035
aging GO:0007568 143 0.035
purine containing compound metabolic process GO:0072521 155 0.033
Human
covalent chromatin modification GO:0016569 106 0.033
cellular amino acid metabolic process GO:0006520 61 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.031
purine nucleotide metabolic process GO:0006163 146 0.031
Human
nucleoside triphosphate metabolic process GO:0009141 120 0.031
Human
mitotic nuclear division GO:0007067 213 0.030
response to organic substance GO:0010033 284 0.029
glycosyl compound catabolic process GO:1901658 112 0.029
Human
negative regulation of mitotic cell cycle GO:0045930 109 0.029
dendrite development GO:0016358 204 0.029
regulation of organelle organization GO:0033043 196 0.029
negative regulation of cellular metabolic process GO:0031324 382 0.028
Human
aromatic compound catabolic process GO:0019439 166 0.028
Human
ribonucleoside metabolic process GO:0009119 127 0.027
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.027
dna integrity checkpoint GO:0031570 81 0.027
nucleobase containing compound catabolic process GO:0034655 165 0.027
Human
nucleotide catabolic process GO:0009166 109 0.026
Human
dna damage checkpoint GO:0000077 78 0.026
enzyme linked receptor protein signaling pathway GO:0007167 179 0.026
negative regulation of cell cycle process GO:0010948 109 0.026
dna packaging GO:0006323 91 0.025
response to bacterium GO:0009617 198 0.025
response to oxygen containing compound GO:1901700 200 0.024
purine nucleoside catabolic process GO:0006152 112 0.024
Human
intracellular signal transduction GO:0035556 300 0.024
response to biotic stimulus GO:0009607 294 0.024
ribonucleotide catabolic process GO:0009261 109 0.024
Human
eye development GO:0001654 323 0.023
positive regulation of rna metabolic process GO:0051254 271 0.022
regulation of anatomical structure morphogenesis GO:0022603 242 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.022
organophosphate metabolic process GO:0019637 195 0.022
Human
protein complex assembly GO:0006461 200 0.022
purine nucleoside triphosphate catabolic process GO:0009146 108 0.021
Human
body morphogenesis GO:0010171 2 0.021
amine metabolic process GO:0009308 12 0.021
peptidyl arginine methylation GO:0018216 5 0.021
positive regulation of cellular biosynthetic process GO:0031328 316 0.020
regulation of growth GO:0040008 233 0.020
ribonucleoside catabolic process GO:0042454 112 0.020
Human
small molecule metabolic process GO:0044281 305 0.020
Human
positive regulation of response to stimulus GO:0048584 323 0.019
regulation of mitotic cell cycle phase transition GO:1901990 130 0.019
organonitrogen compound catabolic process GO:1901565 128 0.019
Human
carboxylic acid metabolic process GO:0019752 92 0.019
organelle fission GO:0048285 340 0.019
purine ribonucleotide metabolic process GO:0009150 145 0.019
Human
macromolecular complex assembly GO:0065003 256 0.018
negative regulation of cell cycle GO:0045786 116 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
cell cycle dna replication GO:0044786 23 0.017
nucleoside metabolic process GO:0009116 127 0.017
Human
centrosome organization GO:0051297 163 0.017
ribonucleotide metabolic process GO:0009259 145 0.017
Human
single organism intracellular transport GO:1902582 207 0.017
mitotic dna integrity checkpoint GO:0044774 75 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
actin filament based process GO:0030029 220 0.017
regulation of cellular component biogenesis GO:0044087 201 0.017
nucleoside phosphate catabolic process GO:1901292 110 0.017
Human
chromatin modification GO:0016568 147 0.016
purine nucleoside metabolic process GO:0042278 127 0.016
Human
regulation of immune system process GO:0002682 176 0.016
cellular macromolecular complex assembly GO:0034622 153 0.016
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.016
regulation of immune response GO:0050776 118 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
Human
actin cytoskeleton organization GO:0030036 206 0.016
negative regulation of molecular function GO:0044092 51 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.015
cell cycle phase transition GO:0044770 140 0.015
protein localization GO:0008104 284 0.015
embryo development ending in birth or egg hatching GO:0009792 152 0.015
regulation of cell cycle phase transition GO:1901987 130 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.015
Human
purine ribonucleotide catabolic process GO:0009154 109 0.015
Human
death GO:0016265 284 0.015
defense response to gram negative bacterium GO:0050829 94 0.015
organophosphate catabolic process GO:0046434 112 0.015
Human
central nervous system development GO:0007417 201 0.015
nucleoside catabolic process GO:0009164 112 0.015
Human
regulation of catabolic process GO:0009894 170 0.015
segmentation GO:0035282 207 0.015
immune system process GO:0002376 347 0.014
purine containing compound catabolic process GO:0072523 112 0.014
Human
positive regulation of multicellular organismal process GO:0051240 143 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
positive regulation of nucleic acid templated transcription GO:1903508 266 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
Human
microtubule organizing center organization GO:0031023 168 0.014
regulation of hydrolase activity GO:0051336 97 0.014
Human
maintenance of location GO:0051235 73 0.014
centrosome cycle GO:0007098 137 0.014
gland development GO:0048732 191 0.014
purine ribonucleoside catabolic process GO:0046130 112 0.014
Human
organ growth GO:0035265 56 0.014
rna processing GO:0006396 147 0.014
chromatin assembly or disassembly GO:0006333 52 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.013
protein phosphorylation GO:0006468 169 0.013
appendage morphogenesis GO:0035107 397 0.013
regulation of response to stress GO:0080134 200 0.013
positive regulation of developmental process GO:0051094 143 0.013
regulation of developmental growth GO:0048638 174 0.013
homeostatic process GO:0042592 199 0.013
proteolysis GO:0006508 192 0.013
single organism cellular localization GO:1902580 180 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
ras protein signal transduction GO:0007265 88 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
sister chromatid segregation GO:0000819 92 0.013
regulation of notch signaling pathway GO:0008593 100 0.013
cellular amine metabolic process GO:0044106 12 0.013
immune response GO:0006955 246 0.013
chromatin silencing GO:0006342 76 0.012
organic acid metabolic process GO:0006082 103 0.012
positive regulation of immune system process GO:0002684 68 0.012
programmed cell death GO:0012501 257 0.012
dna dependent dna replication GO:0006261 17 0.012
regulation of cellular component size GO:0032535 98 0.012
regulation of transport GO:0051049 181 0.012
ribonucleoside triphosphate metabolic process GO:0009199 119 0.012
Human
erbb signaling pathway GO:0038127 58 0.012
regulation of defense response GO:0031347 102 0.012
defense response to bacterium GO:0042742 178 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
Human
forebrain development GO:0030900 2 0.012
posttranscriptional gene silencing GO:0016441 46 0.012
mitotic cell cycle checkpoint GO:0007093 88 0.012
cellular ketone metabolic process GO:0042180 24 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
negative regulation of developmental process GO:0051093 201 0.012
regulation of cellular localization GO:0060341 136 0.012
positive regulation of ras gtpase activity GO:0032320 36 0.012
positive regulation of molecular function GO:0044093 136 0.011
Human
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
Human
positive regulation of catalytic activity GO:0043085 118 0.011
Human
negative regulation of signaling GO:0023057 219 0.011
nucleotide metabolic process GO:0009117 161 0.011
Human
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.011
Human
camera type eye development GO:0043010 4 0.011
intracellular transport GO:0046907 228 0.011
immune response activating signal transduction GO:0002757 2 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
Human
regulation of ras gtpase activity GO:0032318 38 0.011
nucleosome assembly GO:0006334 35 0.011
camera type eye morphogenesis GO:0048593 2 0.011
phosphorylation GO:0016310 294 0.011
regulation of cytoskeleton organization GO:0051493 89 0.011
gene silencing GO:0016458 138 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
mitotic sister chromatid segregation GO:0000070 87 0.011
negative regulation of programmed cell death GO:0043069 72 0.011
macromolecule catabolic process GO:0009057 161 0.011
positive regulation of signaling GO:0023056 243 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
Human
positive regulation of gene expression GO:0010628 290 0.010
response to lipopolysaccharide GO:0032496 4 0.010
posttranscriptional regulation of gene expression GO:0010608 145 0.010
centrosome duplication GO:0051298 121 0.010
regulation of purine nucleotide metabolic process GO:1900542 62 0.010
gtp catabolic process GO:0006184 72 0.010
vesicle mediated transport GO:0016192 381 0.010
cell death GO:0008219 279 0.010

spel1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org