Drosophila melanogaster

48 known processes

Pgm (Dmel_CG5165)

Phosphogluconate mutase

(Aliases: pgm,PGM,PGM-1,CG5165,Dmel\CG5165)

Pgm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 61 0.558
carboxylic acid metabolic process GO:0019752 92 0.418
carbohydrate biosynthetic process GO:0016051 17 0.399
organic acid metabolic process GO:0006082 103 0.382
acetaldehyde metabolic process GO:0006117 5 0.365
pyruvate metabolic process GO:0006090 7 0.296
oxoacid metabolic process GO:0043436 103 0.255
nad metabolic process GO:0019674 1 0.243
cellular carbohydrate metabolic process GO:0044262 22 0.238
glutamate metabolic process GO:0006536 5 0.204
monocarboxylic acid metabolic process GO:0032787 29 0.173
response to hexose GO:0009746 3 0.151
catabolic process GO:0009056 409 0.142
regulation of cellular ketone metabolic process GO:0010565 3 0.129
response to organic substance GO:0010033 284 0.123
single organism carbohydrate metabolic process GO:0044723 72 0.114
negative regulation of biosynthetic process GO:0009890 277 0.106
organonitrogen compound metabolic process GO:1901564 318 0.104
carbohydrate metabolic process GO:0005975 82 0.101
organic substance catabolic process GO:1901575 308 0.099
response to monosaccharide GO:0034284 4 0.096
immune system process GO:0002376 347 0.093
small molecule metabolic process GO:0044281 305 0.092
single organism catabolic process GO:0044712 228 0.083
oxidoreduction coenzyme metabolic process GO:0006733 2 0.080
response to oxygen containing compound GO:1901700 200 0.077
cellular ketone metabolic process GO:0042180 24 0.069
carbohydrate catabolic process GO:0016052 7 0.068
response to glucose GO:0009749 2 0.068
energy derivation by oxidation of organic compounds GO:0015980 32 0.067
thiosulfate transport GO:0015709 2 0.064
secretion by cell GO:0032940 101 0.064
cellular catabolic process GO:0044248 372 0.063
regulation of glucan biosynthetic process GO:0010962 1 0.059
aging GO:0007568 143 0.058
response to organophosphorus GO:0046683 2 0.057
determination of adult lifespan GO:0008340 137 0.056
multicellular organismal aging GO:0010259 140 0.052
pyridine containing compound metabolic process GO:0072524 3 0.052
lateral inhibition GO:0046331 206 0.052
response to biotic stimulus GO:0009607 294 0.051
multi multicellular organism process GO:0044706 123 0.051
reproductive behavior GO:0019098 122 0.050
monosaccharide metabolic process GO:0005996 9 0.048
Mouse
pyridine nucleotide metabolic process GO:0019362 2 0.046
imaginal disc derived appendage development GO:0048737 399 0.046
cellular carbohydrate biosynthetic process GO:0034637 7 0.045
homeostatic process GO:0042592 199 0.044
alpha amino acid metabolic process GO:1901605 20 0.044
hexose metabolic process GO:0019318 8 0.043
Mouse
epithelial cell differentiation GO:0030855 322 0.042
negative regulation of cellular biosynthetic process GO:0031327 277 0.040
glucose metabolic process GO:0006006 5 0.040
Mouse
posttranscriptional regulation of gene expression GO:0010608 145 0.039
positive regulation of macromolecule metabolic process GO:0010604 405 0.037
single organism biosynthetic process GO:0044711 206 0.037
spermatogenesis GO:0007283 200 0.037
single organism carbohydrate catabolic process GO:0044724 7 0.037
defense response GO:0006952 300 0.036
sterol metabolic process GO:0016125 12 0.036
cellular amine metabolic process GO:0044106 12 0.036
death GO:0016265 284 0.034
post embryonic appendage morphogenesis GO:0035120 385 0.031
response to other organism GO:0051707 293 0.031
appendage morphogenesis GO:0035107 397 0.030
oxidation reduction process GO:0055114 123 0.030
cell maturation GO:0048469 144 0.030
camera type eye development GO:0043010 4 0.030
peptide metabolic process GO:0006518 80 0.029
cellular biogenic amine catabolic process GO:0042402 1 0.029
positive regulation of cell communication GO:0010647 250 0.028
positive regulation of secretion GO:0051047 22 0.027
epidermis development GO:0008544 65 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.026
response to ethanol GO:0045471 59 0.025
appendage development GO:0048736 401 0.025
heart morphogenesis GO:0003007 32 0.025
positive regulation of signaling GO:0023056 243 0.025
cellular component assembly involved in morphogenesis GO:0010927 151 0.025
cellular carbohydrate catabolic process GO:0044275 2 0.024
wing disc morphogenesis GO:0007472 344 0.024
cellular macromolecular complex assembly GO:0034622 153 0.024
innate immune response GO:0045087 144 0.024
glutamine family amino acid metabolic process GO:0009064 12 0.023
synaptic transmission GO:0007268 288 0.023
open tracheal system development GO:0007424 204 0.021
positive regulation of biosynthetic process GO:0009891 316 0.021
glycolytic process GO:0006096 6 0.021
response to external biotic stimulus GO:0043207 293 0.021
macromolecule catabolic process GO:0009057 161 0.020
detection of hexose stimulus GO:0009732 1 0.020
nadh metabolic process GO:0006734 1 0.020
lipid localization GO:0010876 54 0.020
protein complex assembly GO:0006461 200 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.020
retina development in camera type eye GO:0060041 4 0.020
organonitrogen compound biosynthetic process GO:1901566 117 0.019
response to endogenous stimulus GO:0009719 119 0.019
cellular modified amino acid metabolic process GO:0006575 45 0.019
chemical homeostasis GO:0048878 92 0.019
regulation of developmental growth GO:0048638 174 0.019
male gamete generation GO:0048232 201 0.019
larval development GO:0002164 104 0.019
somatic muscle development GO:0007525 66 0.019
regionalization GO:0003002 416 0.018
nicotinamide nucleotide metabolic process GO:0046496 2 0.018
cell type specific apoptotic process GO:0097285 38 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.017
amine catabolic process GO:0009310 1 0.017
organic hydroxy compound catabolic process GO:1901616 4 0.017
neuron projection guidance GO:0097485 241 0.016
amine metabolic process GO:0009308 12 0.016
programmed cell death GO:0012501 257 0.016
response to heat GO:0009408 63 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
epithelial tube morphogenesis GO:0060562 88 0.016
negative regulation of developmental process GO:0051093 201 0.016
carbohydrate derivative metabolic process GO:1901135 217 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.016
cellular response to chemical stimulus GO:0070887 199 0.015
cell migration GO:0016477 238 0.015
secretion GO:0046903 109 0.015
detection of glucose GO:0051594 1 0.015
positive regulation of cell death GO:0010942 69 0.015
cellular protein complex assembly GO:0043623 71 0.015
regulation of localization GO:0032879 275 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
cellular protein modification process GO:0006464 438 0.014
negative regulation of cell differentiation GO:0045596 143 0.014
cell death GO:0008219 279 0.014
reproductive structure development GO:0048608 74 0.014
neurotransmitter catabolic process GO:0042135 1 0.014
small molecule catabolic process GO:0044282 21 0.014
cell aging GO:0007569 2 0.014
negative regulation of cellular metabolic process GO:0031324 382 0.014
response to abiotic stimulus GO:0009628 341 0.014
macromolecular complex assembly GO:0065003 256 0.014
multi organism behavior GO:0051705 175 0.013
negative regulation of cell cycle GO:0045786 116 0.013
protein modification process GO:0036211 438 0.013
nuclear division GO:0000280 332 0.013
regulation of multicellular organismal development GO:2000026 414 0.012
positive regulation of secretion by cell GO:1903532 20 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
regulation of anatomical structure size GO:0090066 163 0.012
protein complex biogenesis GO:0070271 201 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
positive regulation of glycogen biosynthetic process GO:0045725 1 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
negative regulation of neuroblast proliferation GO:0007406 27 0.011
chromosome segregation GO:0007059 157 0.011
organelle assembly GO:0070925 198 0.011
sensory organ morphogenesis GO:0090596 260 0.011
lipid metabolic process GO:0006629 121 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
adult locomotory behavior GO:0008344 76 0.011
glutathione metabolic process GO:0006749 37 0.011
cellular homeostasis GO:0019725 80 0.011
tricarboxylic acid metabolic process GO:0072350 1 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
water homeostasis GO:0030104 3 0.011
regulation of cell cycle GO:0051726 291 0.010
transition metal ion homeostasis GO:0055076 17 0.010
cellular amino acid biosynthetic process GO:0008652 9 0.010
gland development GO:0048732 191 0.010
acyl coa biosynthetic process GO:0071616 2 0.010
imaginal disc derived appendage morphogenesis GO:0035114 395 0.010
axon guidance GO:0007411 233 0.010
age dependent general metabolic decline GO:0007571 3 0.010
ion transport GO:0006811 145 0.010
positive regulation of response to stimulus GO:0048584 323 0.010
telencephalon development GO:0021537 2 0.010

Pgm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.063
acquired metabolic disease DOID:0060158 0 0.063
disease of anatomical entity DOID:7 0 0.053
immune system disease DOID:2914 0 0.048
anemia DOID:2355 0 0.048
hematopoietic system disease DOID:74 0 0.048
carbohydrate metabolism disease DOID:0050013 0 0.032
glucose metabolism disease DOID:4194 0 0.032
inherited metabolic disorder DOID:655 0 0.011