Drosophila melanogaster

0 known processes

DNApol-alpha73 (Dmel_CG5923)

DNA polymerase alpha 73kD

(Aliases: DNApol-alpha72,DNApolalpha,Dmel\CG5923,Dmpol alpha,DNApol-alpha,DNA polalpha,CG5923,Pol,DNA pol-73,POLA,polalpha,pol alpha,Polalpha)

DNApol-alpha73 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna replication GO:0006260 48 0.812
Yeast
cellular response to dna damage stimulus GO:0006974 223 0.553
dna metabolic process GO:0006259 227 0.417
Yeast
nuclear dna replication GO:0033260 1 0.406
regulation of cell cycle process GO:0010564 181 0.393
regulation of cell cycle GO:0051726 291 0.357
dna repair GO:0006281 54 0.352
negative regulation of cell cycle process GO:0010948 109 0.348
mitotic cell cycle phase transition GO:0044772 138 0.304
regulation of cell cycle phase transition GO:1901987 130 0.288
cell cycle dna replication GO:0044786 23 0.264
mitotic g2 m transition checkpoint GO:0044818 70 0.253
mitotic dna damage checkpoint GO:0044773 74 0.195
cellular catabolic process GO:0044248 372 0.184
dna integrity checkpoint GO:0031570 81 0.176
negative regulation of gene expression GO:0010629 387 0.170
negative regulation of cellular metabolic process GO:0031324 382 0.155
mitotic dna integrity checkpoint GO:0044774 75 0.141
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.138
catabolic process GO:0009056 409 0.137
heterocycle catabolic process GO:0046700 166 0.119
negative regulation of cell cycle phase transition GO:1901988 103 0.118
positive regulation of cellular biosynthetic process GO:0031328 316 0.118
regulation of molecular function GO:0065009 217 0.110
organic substance catabolic process GO:1901575 308 0.109
dna dependent dna replication GO:0006261 17 0.108
Yeast
regulation of mitotic cell cycle phase transition GO:1901990 130 0.107
mitotic g2 dna damage checkpoint GO:0007095 69 0.106
protein modification process GO:0036211 438 0.102
organonitrogen compound metabolic process GO:1901564 318 0.097
negative regulation of cell communication GO:0010648 223 0.096
mitotic nuclear division GO:0007067 213 0.094
cellular nitrogen compound catabolic process GO:0044270 165 0.091
positive regulation of biosynthetic process GO:0009891 316 0.091
cell cycle phase transition GO:0044770 140 0.088
spindle organization GO:0007051 253 0.087
nuclear division GO:0000280 332 0.083
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.081
macromolecule catabolic process GO:0009057 161 0.078
eye development GO:0001654 323 0.072
cell cycle checkpoint GO:0000075 95 0.072
negative regulation of signaling GO:0023057 219 0.072
organelle fission GO:0048285 340 0.070
regulation of localization GO:0032879 275 0.069
regulation of mitotic cell cycle GO:0007346 190 0.068
g2 dna damage checkpoint GO:0031572 69 0.066
centrosome organization GO:0051297 163 0.066
double strand break repair GO:0006302 26 0.063
small molecule metabolic process GO:0044281 305 0.063
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.063
regulation of dna metabolic process GO:0051052 34 0.062
negative regulation of cell cycle GO:0045786 116 0.061
negative regulation of mitotic cell cycle GO:0045930 109 0.060
negative regulation of rna biosynthetic process GO:1902679 240 0.060
cell proliferation GO:0008283 299 0.059
negative regulation of rna metabolic process GO:0051253 251 0.058
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.058
spindle elongation GO:0051231 83 0.057
negative regulation of response to stimulus GO:0048585 258 0.057
organic cyclic compound catabolic process GO:1901361 168 0.057
mitotic cell cycle checkpoint GO:0007093 88 0.055
nucleobase containing compound catabolic process GO:0034655 165 0.054
dna recombination GO:0006310 32 0.053
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.053
dna damage checkpoint GO:0000077 78 0.051
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.051
eye morphogenesis GO:0048592 260 0.049
regulation of catalytic activity GO:0050790 185 0.049
single organism biosynthetic process GO:0044711 206 0.048
regulation of catabolic process GO:0009894 170 0.047
dna endoreduplication GO:0042023 22 0.047
aromatic compound catabolic process GO:0019439 166 0.047
regulation of protein metabolic process GO:0051246 256 0.046
death GO:0016265 284 0.046
negative regulation of signal transduction GO:0009968 206 0.046
macromolecular complex assembly GO:0065003 256 0.045
cell division GO:0051301 248 0.044
cellular macromolecule catabolic process GO:0044265 136 0.042
proteolysis GO:0006508 192 0.040
dna biosynthetic process GO:0071897 24 0.040
Yeast
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.040
positive regulation of rna biosynthetic process GO:1902680 266 0.038
single organism catabolic process GO:0044712 228 0.038
dna replication initiation GO:0006270 6 0.037
Yeast
growth GO:0040007 359 0.037
multicellular organism growth GO:0035264 46 0.035
organic substance transport GO:0071702 257 0.034
positive regulation of macromolecule metabolic process GO:0010604 405 0.034
negative regulation of biosynthetic process GO:0009890 277 0.033
nucleotide metabolic process GO:0009117 161 0.032
cellular protein modification process GO:0006464 438 0.031
nucleobase containing small molecule metabolic process GO:0055086 174 0.030
nucleoside phosphate metabolic process GO:0006753 162 0.030
camera type eye development GO:0043010 4 0.029
tissue morphogenesis GO:0048729 297 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.029
programmed cell death GO:0012501 257 0.029
nucleoside metabolic process GO:0009116 127 0.029
regulation of gene expression epigenetic GO:0040029 128 0.028
negative regulation of nucleic acid templated transcription GO:1903507 240 0.028
protein dna complex assembly GO:0065004 63 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.027
negative regulation of cellular biosynthetic process GO:0031327 277 0.027
mitotic spindle elongation GO:0000022 81 0.026
purine containing compound metabolic process GO:0072521 155 0.026
protein localization GO:0008104 284 0.026
post embryonic appendage morphogenesis GO:0035120 385 0.025
regulation of cellular response to stress GO:0080135 89 0.025
purine nucleotide metabolic process GO:0006163 146 0.025
mitotic spindle organization GO:0007052 220 0.025
positive regulation of molecular function GO:0044093 136 0.025
cell motility GO:0048870 251 0.024
protein catabolic process GO:0030163 101 0.024
protein complex biogenesis GO:0070271 201 0.023
organonitrogen compound catabolic process GO:1901565 128 0.023
ribonucleotide catabolic process GO:0009261 109 0.022
negative regulation of transcription dna templated GO:0045892 237 0.022
regulation of cell differentiation GO:0045595 302 0.022
establishment of localization in cell GO:0051649 402 0.022
purine ribonucleotide catabolic process GO:0009154 109 0.022
compound eye development GO:0048749 307 0.021
nucleotide catabolic process GO:0009166 109 0.021
regulation of cell morphogenesis GO:0022604 163 0.021
purine nucleotide catabolic process GO:0006195 109 0.021
compound eye morphogenesis GO:0001745 249 0.020
intracellular signal transduction GO:0035556 300 0.020
single organism cellular localization GO:1902580 180 0.020
membrane organization GO:0061024 112 0.020
protein transport GO:0015031 155 0.020
ubiquitin dependent protein catabolic process GO:0006511 78 0.020
cell death GO:0008219 279 0.019
positive regulation of catalytic activity GO:0043085 118 0.019
establishment of cell polarity GO:0030010 40 0.019
cellular protein localization GO:0034613 160 0.019
ribonucleoside triphosphate catabolic process GO:0009203 108 0.019
microtubule organizing center organization GO:0031023 168 0.019
modification dependent macromolecule catabolic process GO:0043632 79 0.019
ribonucleoside triphosphate metabolic process GO:0009199 119 0.019
glycosyl compound metabolic process GO:1901657 127 0.019
morphogenesis of an epithelium GO:0002009 276 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
ribonucleoside catabolic process GO:0042454 112 0.018
cell cell signaling involved in cell fate commitment GO:0045168 210 0.018
heart development GO:0007507 82 0.018
imaginal disc derived appendage morphogenesis GO:0035114 395 0.018
dendrite morphogenesis GO:0048813 199 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
regulation of dna replication GO:0006275 13 0.017
nucleoside triphosphate metabolic process GO:0009141 120 0.017
purine ribonucleoside metabolic process GO:0046128 127 0.017
spermatogenesis GO:0007283 200 0.017
rna processing GO:0006396 147 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
developmental growth GO:0048589 280 0.017
regulation of intracellular signal transduction GO:1902531 236 0.017
appendage morphogenesis GO:0035107 397 0.016
positive regulation of nucleic acid templated transcription GO:1903508 266 0.016
regulation of cell division GO:0051302 72 0.016
purine nucleoside metabolic process GO:0042278 127 0.016
purine nucleoside triphosphate catabolic process GO:0009146 108 0.016
regulation of transport GO:0051049 181 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.016
intracellular transport GO:0046907 228 0.015
cellular macromolecular complex assembly GO:0034622 153 0.015
double strand break repair via homologous recombination GO:0000724 13 0.015
nucleoside monophosphate metabolic process GO:0009123 52 0.015
regulation of hydrolase activity GO:0051336 97 0.015
centrosome duplication GO:0051298 121 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
proteasomal protein catabolic process GO:0010498 59 0.015
sensory organ morphogenesis GO:0090596 260 0.015
organophosphate catabolic process GO:0046434 112 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
purine ribonucleoside catabolic process GO:0046130 112 0.015
double strand break repair via nonhomologous end joining GO:0006303 5 0.015
chromosome organization GO:0051276 360 0.014
Yeast
endocytosis GO:0006897 310 0.014
chromatin organization GO:0006325 207 0.014
dendrite development GO:0016358 204 0.014
organophosphate metabolic process GO:0019637 195 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
regulation of protein catabolic process GO:0042176 55 0.014
nucleoside catabolic process GO:0009164 112 0.014
protein processing GO:0016485 68 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
purine containing compound catabolic process GO:0072523 112 0.014
protein complex assembly GO:0006461 200 0.013
response to nutrient levels GO:0031667 114 0.013
regulation of organelle organization GO:0033043 196 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
regulation of growth GO:0040008 233 0.013
regulation of nervous system development GO:0051960 248 0.013
response to biotic stimulus GO:0009607 294 0.013
homeostatic process GO:0042592 199 0.013
Yeast
transcription from rna polymerase ii promoter GO:0006366 368 0.013
single organism behavior GO:0044708 391 0.013
protein phosphorylation GO:0006468 169 0.013
cellular protein complex assembly GO:0043623 71 0.012
positive regulation of gene expression GO:0010628 290 0.012
compound eye photoreceptor cell differentiation GO:0001751 140 0.012
regulation of multicellular organismal development GO:2000026 414 0.012
negative regulation of dna metabolic process GO:0051053 12 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.012
reproductive structure development GO:0048608 74 0.012
mrna metabolic process GO:0016071 124 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
response to oxygen containing compound GO:1901700 200 0.012
establishment of protein localization GO:0045184 163 0.012
protein targeting GO:0006605 64 0.012
positive regulation of cell cycle process GO:0090068 28 0.012
glutamine family amino acid catabolic process GO:0009065 3 0.012
establishment of protein localization to organelle GO:0072594 62 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
detection of monosaccharide stimulus GO:0034287 1 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
guanosine containing compound catabolic process GO:1901069 74 0.011
salivary gland development GO:0007431 162 0.011
vesicle mediated transport GO:0016192 381 0.011
ncrna 3 end processing GO:0043628 17 0.011
respiratory system development GO:0060541 213 0.011
positive regulation of rna metabolic process GO:0051254 271 0.010
gtp metabolic process GO:0046039 72 0.010
positive regulation of cell cycle GO:0045787 43 0.010
g1 s transition of mitotic cell cycle GO:0000082 31 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010
ribonucleotide metabolic process GO:0009259 145 0.010

DNApol-alpha73 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017