Drosophila melanogaster

42 known processes

l(3)S147910 (Dmel_CG14121)

lethal (3) S147910

(Aliases: 1479/10,Dmel\CG14121,CG14121,anon-WO0172774.86,anon-WO0172774.87,anon-WO0172774.89)

l(3)S147910 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
telomere capping GO:0016233 11 0.722
chromosome organization GO:0051276 360 0.380
dna metabolic process GO:0006259 227 0.335
mitotic nuclear division GO:0007067 213 0.214
homeostatic process GO:0042592 199 0.201
nuclear division GO:0000280 332 0.182
organelle fission GO:0048285 340 0.146
anatomical structure homeostasis GO:0060249 97 0.122
cellular modified amino acid metabolic process GO:0006575 45 0.118
telomere organization GO:0032200 21 0.116
cellular protein modification process GO:0006464 438 0.093
telomere maintenance GO:0000723 21 0.076
protein modification process GO:0036211 438 0.075
phenol containing compound metabolic process GO:0018958 57 0.074
cellular response to dna damage stimulus GO:0006974 223 0.069
neurological system process GO:0050877 358 0.064
mitotic g2 m transition checkpoint GO:0044818 70 0.063
cell cell signaling involved in cell fate commitment GO:0045168 210 0.056
response to bacterium GO:0009617 198 0.055
dna conformation change GO:0071103 105 0.055
carboxylic acid metabolic process GO:0019752 92 0.054
response to organic substance GO:0010033 284 0.054
response to biotic stimulus GO:0009607 294 0.049
intracellular signal transduction GO:0035556 300 0.048
oxoacid metabolic process GO:0043436 103 0.048
axis specification GO:0009798 167 0.048
negative regulation of cell cycle process GO:0010948 109 0.045
multi organism behavior GO:0051705 175 0.045
regulation of anatomical structure morphogenesis GO:0022603 242 0.044
regulation of mitotic cell cycle phase transition GO:1901990 130 0.044
organic acid metabolic process GO:0006082 103 0.043
response to lipopolysaccharide GO:0032496 4 0.041
small molecule metabolic process GO:0044281 305 0.039
chromatin modification GO:0016568 147 0.038
regionalization GO:0003002 416 0.038
chromatin organization GO:0006325 207 0.038
body morphogenesis GO:0010171 2 0.037
mitotic dna integrity checkpoint GO:0044774 75 0.037
tissue morphogenesis GO:0048729 297 0.036
regulation of cell cycle process GO:0010564 181 0.035
g2 dna damage checkpoint GO:0031572 69 0.035
developmental maturation GO:0021700 172 0.034
death GO:0016265 284 0.033
covalent chromatin modification GO:0016569 106 0.033
adult behavior GO:0030534 137 0.033
sensory perception GO:0007600 196 0.033
regulation of phosphorus metabolic process GO:0051174 210 0.032
positive regulation of protein metabolic process GO:0051247 128 0.032
mitotic cell cycle phase transition GO:0044772 138 0.032
negative regulation of cell cycle phase transition GO:1901988 103 0.032
organic hydroxy compound metabolic process GO:1901615 83 0.031
regulation of mitotic cell cycle GO:0007346 190 0.031
mitotic g2 dna damage checkpoint GO:0007095 69 0.030
single organism biosynthetic process GO:0044711 206 0.030
positive regulation of cell migration GO:0030335 2 0.030
transmembrane transport GO:0055085 139 0.029
dorsal ventral pattern formation GO:0009953 133 0.029
mating GO:0007618 120 0.029
response to oxygen containing compound GO:1901700 200 0.029
multi multicellular organism process GO:0044706 123 0.028
regulation of cell cycle phase transition GO:1901987 130 0.028
oocyte construction GO:0007308 112 0.027
ion transport GO:0006811 145 0.027
camera type eye development GO:0043010 4 0.027
lateral inhibition GO:0046331 206 0.027
regulation of cell shape GO:0008360 113 0.026
positive regulation of rna biosynthetic process GO:1902680 266 0.026
ras protein signal transduction GO:0007265 88 0.026
regulation of phosphate metabolic process GO:0019220 210 0.026
macromolecule catabolic process GO:0009057 161 0.026
cell maturation GO:0048469 144 0.026
response to alcohol GO:0097305 95 0.026
cellular catabolic process GO:0044248 372 0.025
sister chromatid segregation GO:0000819 92 0.025
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.025
organonitrogen compound metabolic process GO:1901564 318 0.025
response to mechanical stimulus GO:0009612 28 0.025
metal ion homeostasis GO:0055065 44 0.024
response to nitrogen compound GO:1901698 90 0.024
single organism behavior GO:0044708 391 0.024
organelle assembly GO:0070925 198 0.024
small gtpase mediated signal transduction GO:0007264 88 0.024
negative regulation of cell cycle GO:0045786 116 0.023
cell cycle phase transition GO:0044770 140 0.023
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
cellular homeostasis GO:0019725 80 0.023
oocyte axis specification GO:0007309 108 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
chorion containing eggshell formation GO:0007304 105 0.023
protein phosphorylation GO:0006468 169 0.023
response to organonitrogen compound GO:0010243 75 0.023
regulation of protein metabolic process GO:0051246 256 0.023
protein dna complex subunit organization GO:0071824 86 0.023
regulation of behavior GO:0050795 75 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.023
dna packaging GO:0006323 91 0.023
segmentation GO:0035282 207 0.022
organic substance catabolic process GO:1901575 308 0.022
forebrain development GO:0030900 2 0.022
response to other organism GO:0051707 293 0.022
regulation of small gtpase mediated signal transduction GO:0051056 93 0.022
locomotory behavior GO:0007626 176 0.022
positive regulation of phosphorylation GO:0042327 87 0.022
mesenchymal cell differentiation GO:0048762 1 0.022
cellular nitrogen compound catabolic process GO:0044270 165 0.021
rna processing GO:0006396 147 0.021
cellular macromolecule catabolic process GO:0044265 136 0.021
positive regulation of signaling GO:0023056 243 0.021
cognition GO:0050890 141 0.021
regulation of protein modification process GO:0031399 112 0.021
positive regulation of cellular biosynthetic process GO:0031328 316 0.021
dna integrity checkpoint GO:0031570 81 0.021
response to organic cyclic compound GO:0014070 89 0.021
regulation of cell development GO:0060284 215 0.021
protein modification by small protein conjugation or removal GO:0070647 106 0.021
neural precursor cell proliferation GO:0061351 75 0.021
cell migration GO:0016477 238 0.021
positive regulation of gene expression GO:0010628 290 0.021
defense response GO:0006952 300 0.021
response to endogenous stimulus GO:0009719 119 0.020
organic substance transport GO:0071702 257 0.020
positive regulation of cellular protein metabolic process GO:0032270 118 0.020
cell division GO:0051301 248 0.020
epithelial cell differentiation GO:0030855 322 0.020
respiratory system development GO:0060541 213 0.020
lipid metabolic process GO:0006629 121 0.020
chaeta development GO:0022416 97 0.020
mitotic dna damage checkpoint GO:0044773 74 0.020
regulation of intracellular signal transduction GO:1902531 236 0.020
protein localization GO:0008104 284 0.020
cellular amino acid metabolic process GO:0006520 61 0.020
cytoplasm organization GO:0007028 64 0.019
regulation of cell death GO:0010941 173 0.019
response to external biotic stimulus GO:0043207 293 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.019
regulation of multicellular organismal development GO:2000026 414 0.019
cell death GO:0008219 279 0.019
positive regulation of response to stimulus GO:0048584 323 0.019
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.019
actin filament based process GO:0030029 220 0.019
imaginal disc derived appendage development GO:0048737 399 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.019
steroid catabolic process GO:0006706 1 0.019
biological adhesion GO:0022610 138 0.019
leg disc morphogenesis GO:0007478 80 0.019
mesenchymal cell development GO:0014031 1 0.018
vesicle mediated transport GO:0016192 381 0.018
germarium derived egg chamber formation GO:0007293 101 0.018
regulation of programmed cell death GO:0043067 152 0.018
secretion GO:0046903 109 0.018
appendage development GO:0048736 401 0.018
wing disc pattern formation GO:0035222 66 0.018
cell motility GO:0048870 251 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
dna geometric change GO:0032392 16 0.018
cell proliferation GO:0008283 299 0.018
positive regulation of molecular function GO:0044093 136 0.018
inter male aggressive behavior GO:0002121 60 0.017
cell projection assembly GO:0030031 94 0.017
cellular response to lipopolysaccharide GO:0071222 3 0.017
pigment metabolic process GO:0042440 84 0.017
chromatin remodeling GO:0006338 72 0.017
actin cytoskeleton organization GO:0030036 206 0.017
response to abiotic stimulus GO:0009628 341 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.017
regulation of cellular localization GO:0060341 136 0.017
regulation of ras protein signal transduction GO:0046578 93 0.017
morphogenesis of an epithelium GO:0002009 276 0.017
positive regulation of phosphate metabolic process GO:0045937 139 0.017
cell adhesion GO:0007155 136 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
phosphorylation GO:0016310 294 0.016
positive regulation of biosynthetic process GO:0009891 316 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
compound eye development GO:0048749 307 0.016
dna duplex unwinding GO:0032508 16 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
cellular amine metabolic process GO:0044106 12 0.016
regulation of gene expression epigenetic GO:0040029 128 0.016
carbohydrate metabolic process GO:0005975 82 0.016
regulation of neurogenesis GO:0050767 158 0.016
retina development in camera type eye GO:0060041 4 0.016
courtship behavior GO:0007619 68 0.016
regulation of catalytic activity GO:0050790 185 0.016
meiotic nuclear division GO:0007126 151 0.016
mitotic cell cycle checkpoint GO:0007093 88 0.016
male mating behavior GO:0060179 70 0.016
glutathione metabolic process GO:0006749 37 0.016
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.016
chemical homeostasis GO:0048878 92 0.016
renal tubule development GO:0061326 64 0.015
synaptic transmission GO:0007268 288 0.015
regulation of cell morphogenesis GO:0022604 163 0.015
response to nutrient levels GO:0031667 114 0.015
imaginal disc pattern formation GO:0007447 91 0.015
protein modification by small protein conjugation GO:0032446 79 0.015
heart process GO:0003015 37 0.015
positive regulation of cell communication GO:0010647 250 0.015
detection of stimulus GO:0051606 156 0.015
aggressive behavior GO:0002118 63 0.015
behavioral response to ethanol GO:0048149 49 0.015
negative regulation of cell death GO:0060548 81 0.015
carboxylic acid transport GO:0046942 18 0.015
cellular ion homeostasis GO:0006873 39 0.015
multicellular organismal reproductive behavior GO:0033057 110 0.015
kidney development GO:0001822 3 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
phagocytosis GO:0006909 215 0.015
ion homeostasis GO:0050801 55 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
rna localization GO:0006403 115 0.014
mitotic spindle organization GO:0007052 220 0.014
ncrna 3 end processing GO:0043628 17 0.014
establishment of localization in cell GO:0051649 402 0.014
appendage morphogenesis GO:0035107 397 0.014
mitotic sister chromatid segregation GO:0000070 87 0.014
acylglycerol catabolic process GO:0046464 3 0.014
cellular ketone metabolic process GO:0042180 24 0.014
proteolysis GO:0006508 192 0.014
cellular response to organic substance GO:0071310 132 0.014
eye morphogenesis GO:0048592 260 0.014
endocytosis GO:0006897 310 0.014
response to extracellular stimulus GO:0009991 116 0.014
positive regulation of cellular component biogenesis GO:0044089 80 0.014
inorganic cation transmembrane transport GO:0098662 61 0.014
positive regulation of ras protein signal transduction GO:0046579 43 0.014
xenobiotic catabolic process GO:0042178 1 0.014
catabolic process GO:0009056 409 0.014
post embryonic appendage morphogenesis GO:0035120 385 0.014
dna repair GO:0006281 54 0.014
mitotic sister chromatid separation GO:0051306 30 0.013
androgen metabolic process GO:0008209 1 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
anion transport GO:0006820 41 0.013
meiotic cell cycle GO:0051321 171 0.013
taxis GO:0042330 304 0.013
peripheral nervous system development GO:0007422 52 0.013
response to alkaloid GO:0043279 26 0.013
reproductive behavior GO:0019098 122 0.013
cellular response to oxygen containing compound GO:1901701 79 0.013
regulation of molecular function GO:0065009 217 0.013
histone modification GO:0016570 106 0.013
cation transport GO:0006812 110 0.013
nitrogen compound transport GO:0071705 85 0.013
sensory organ morphogenesis GO:0090596 260 0.013
cytoplasmic transport GO:0016482 130 0.013
regulation of cell cycle GO:0051726 291 0.013
mating behavior GO:0007617 106 0.013
programmed cell death GO:0012501 257 0.013
positive regulation of cellular component organization GO:0051130 156 0.013
generation of precursor metabolites and energy GO:0006091 42 0.013
sensory perception of pain GO:0019233 4 0.013
mapk cascade GO:0000165 107 0.013
monocarboxylic acid transport GO:0015718 3 0.013
vitamin metabolic process GO:0006766 2 0.013
water homeostasis GO:0030104 3 0.013
centrosome duplication GO:0051298 121 0.013
embryonic axis specification GO:0000578 107 0.013
establishment of protein localization GO:0045184 163 0.013
detection of chemical stimulus GO:0009593 93 0.013
protein prenylation GO:0018342 3 0.012
notch signaling pathway GO:0007219 120 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.012
gene silencing GO:0016458 138 0.012
innate immune response GO:0045087 144 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
centrosome organization GO:0051297 163 0.012
regulation of phosphorylation GO:0042325 147 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.012
cellular amide metabolic process GO:0043603 80 0.012
eggshell formation GO:0030703 105 0.012
renal system development GO:0072001 72 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
response to copper ion GO:0046688 4 0.012
organelle localization GO:0051640 148 0.012
amine metabolic process GO:0009308 12 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
imaginal disc derived leg segmentation GO:0036011 26 0.012
histolysis GO:0007559 102 0.012
regulation of synapse structure and activity GO:0050803 128 0.012
negative regulation of cell proliferation GO:0008285 69 0.012
multi organism reproductive behavior GO:0044705 121 0.012
maternal determination of anterior posterior axis embryo GO:0008358 74 0.012
regulation of neural precursor cell proliferation GO:2000177 35 0.012
spindle organization GO:0007051 253 0.012
learning or memory GO:0007611 141 0.012
positive regulation of neuron apoptotic process GO:0043525 1 0.012
inorganic ion transmembrane transport GO:0098660 73 0.012
chromatin assembly or disassembly GO:0006333 52 0.012
positive regulation of lipid metabolic process GO:0045834 4 0.012
connective tissue development GO:0061448 3 0.012
hematopoietic progenitor cell differentiation GO:0002244 1 0.012
female meiotic division GO:0007143 70 0.012
secretion by cell GO:0032940 101 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
endomembrane system organization GO:0010256 119 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
blastoderm segmentation GO:0007350 159 0.012
aromatic compound catabolic process GO:0019439 166 0.012
negative regulation of dna dependent dna replication GO:2000104 2 0.012
telencephalon development GO:0021537 2 0.012
cellular metal ion homeostasis GO:0006875 31 0.012
peptidyl lysine modification GO:0018205 57 0.012
regulation of transferase activity GO:0051338 58 0.012
response to temperature stimulus GO:0009266 106 0.012
muscle organ development GO:0007517 127 0.012
hindbrain development GO:0030902 2 0.011
negative regulation of cellular metabolic process GO:0031324 382 0.011
cellular response to endogenous stimulus GO:0071495 80 0.011
regulation of intracellular transport GO:0032386 64 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
regulation of epithelial cell differentiation GO:0030856 4 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
regulation of nuclear division GO:0051783 58 0.011
metal ion transport GO:0030001 74 0.011
single organism carbohydrate metabolic process GO:0044723 72 0.011
regulation of transport GO:0051049 181 0.011
olfactory behavior GO:0042048 97 0.011
single organism catabolic process GO:0044712 228 0.011
regulation of cell division GO:0051302 72 0.011
eye development GO:0001654 323 0.011
leg disc development GO:0035218 92 0.011
open tracheal system development GO:0007424 204 0.011
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.011
regulation of chromosome organization GO:0033044 64 0.011
stem cell differentiation GO:0048863 117 0.011
response to calcium ion GO:0051592 1 0.011
heterocycle catabolic process GO:0046700 166 0.011
hormone catabolic process GO:0042447 3 0.011
male courtship behavior GO:0008049 63 0.011
oocyte development GO:0048599 124 0.011
rrna processing GO:0006364 3 0.011
protein dna complex assembly GO:0065004 63 0.011
photoreceptor cell development GO:0042461 96 0.011
posttranscriptional gene silencing by rna GO:0035194 45 0.011
regulation of localization GO:0032879 275 0.011
positive regulation of transport GO:0051050 92 0.011
neuron projection guidance GO:0097485 241 0.011
response to ethanol GO:0045471 59 0.011
renal tubule morphogenesis GO:0061333 44 0.011
negative regulation of nervous system development GO:0051961 92 0.011
immune system process GO:0002376 347 0.011
dna double strand break processing GO:0000729 3 0.011
cellular response to molecule of bacterial origin GO:0071219 3 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
adult locomotory behavior GO:0008344 76 0.011
regulation of response to stress GO:0080134 200 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
cellular cation homeostasis GO:0030003 38 0.010
dna damage checkpoint GO:0000077 78 0.010
regulation of cytoskeleton organization GO:0051493 89 0.010
snrna 3 end processing GO:0034472 14 0.010
dna recombination GO:0006310 32 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.010
cuticle development GO:0042335 86 0.010
salivary gland histolysis GO:0035070 88 0.010
organophosphate metabolic process GO:0019637 195 0.010
instar larval development GO:0002168 55 0.010
chromatin assembly GO:0031497 48 0.010
cell cycle dna replication GO:0044786 23 0.010
cation transmembrane transport GO:0098655 88 0.010
appendage segmentation GO:0035285 26 0.010
peptidyl amino acid modification GO:0018193 105 0.010
molting cycle chitin based cuticle GO:0007591 56 0.010
regulation of multi organism process GO:0043900 131 0.010
pole plasm assembly GO:0007315 61 0.010
cell growth GO:0016049 108 0.010
regulation of secretion by cell GO:1903530 39 0.010
compound eye morphogenesis GO:0001745 249 0.010
imaginal disc derived leg morphogenesis GO:0007480 80 0.010
tube morphogenesis GO:0035239 191 0.010
intracellular transport GO:0046907 228 0.010
regulation of cell projection organization GO:0031344 92 0.010
cell cycle checkpoint GO:0000075 95 0.010
rna 3 end processing GO:0031123 45 0.010
regulation of mitosis GO:0007088 56 0.010
cellular response to ethanol GO:0071361 4 0.010
camera type eye morphogenesis GO:0048593 2 0.010
pigment biosynthetic process GO:0046148 36 0.010
negative regulation of developmental process GO:0051093 201 0.010
epithelial cell migration GO:0010631 148 0.010
autophagic cell death GO:0048102 83 0.010
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.010

l(3)S147910 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.023
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
disease of metabolism DOID:0014667 0 0.011
sensory system disease DOID:0050155 0 0.010
inherited metabolic disorder DOID:655 0 0.010