Drosophila melanogaster

59 known processes

Alg-2 (Dmel_CG40410)

Apoptosis-linked gene-2

(Aliases: CG17661,DALG-2,CG40410,Dmel\CG40410,ALG-2)

Alg-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
wing disc morphogenesis GO:0007472 344 0.094
imaginal disc derived appendage development GO:0048737 399 0.067
imaginal disc derived wing morphogenesis GO:0007476 337 0.064
appendage development GO:0048736 401 0.063
morphogenesis of an epithelium GO:0002009 276 0.063
imaginal disc derived appendage morphogenesis GO:0035114 395 0.062
tissue morphogenesis GO:0048729 297 0.061
appendage morphogenesis GO:0035107 397 0.059
embryonic development via the syncytial blastoderm GO:0001700 148 0.058
cellular catabolic process GO:0044248 372 0.053
actin filament based process GO:0030029 220 0.053
post embryonic appendage morphogenesis GO:0035120 385 0.051
segmentation GO:0035282 207 0.050
vesicle mediated transport GO:0016192 381 0.048
epithelial cell differentiation GO:0030855 322 0.047
embryonic morphogenesis GO:0048598 206 0.047
establishment of tissue polarity GO:0007164 87 0.039
epidermal cell differentiation GO:0009913 51 0.038
regulation of cell cycle GO:0051726 291 0.038
actin cytoskeleton organization GO:0030036 206 0.037
proteolysis GO:0006508 192 0.037
regulation of anatomical structure morphogenesis GO:0022603 242 0.033
morphogenesis of a polarized epithelium GO:0001738 93 0.033
establishment of planar polarity GO:0001736 87 0.033
endocytosis GO:0006897 310 0.032
regulation of multicellular organismal development GO:2000026 414 0.032
nuclear division GO:0000280 332 0.031
organic substance catabolic process GO:1901575 308 0.031
head involution GO:0008258 35 0.031
protein modification process GO:0036211 438 0.030
regulation of establishment of planar polarity GO:0090175 22 0.030
phagocytosis GO:0006909 215 0.029
positive regulation of response to stimulus GO:0048584 323 0.029
regulation of cell cycle process GO:0010564 181 0.028
organelle fission GO:0048285 340 0.028
cellular protein modification process GO:0006464 438 0.028
mitotic cell cycle phase transition GO:0044772 138 0.027
positive regulation of signal transduction GO:0009967 223 0.027
regulation of protein metabolic process GO:0051246 256 0.027
open tracheal system development GO:0007424 204 0.026
positive regulation of cell communication GO:0010647 250 0.026
compound eye development GO:0048749 307 0.026
cellular macromolecule catabolic process GO:0044265 136 0.025
non sensory hair organization GO:0035316 47 0.025
regulation of catalytic activity GO:0050790 185 0.025
regionalization GO:0003002 416 0.025
actin filament organization GO:0007015 126 0.025
mitotic nuclear division GO:0007067 213 0.025
establishment of localization in cell GO:0051649 402 0.024
body morphogenesis GO:0010171 2 0.024
cell cell signaling involved in cell fate commitment GO:0045168 210 0.024
regulation of cellular protein metabolic process GO:0032268 243 0.024
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
sensory organ morphogenesis GO:0090596 260 0.023
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.023
cell division GO:0051301 248 0.023
catabolic process GO:0009056 409 0.022
growth GO:0040007 359 0.022
regulation of anatomical structure size GO:0090066 163 0.022
gland development GO:0048732 191 0.022
macromolecule catabolic process GO:0009057 161 0.022
protein complex assembly GO:0006461 200 0.022
respiratory system development GO:0060541 213 0.022
epithelial cell development GO:0002064 274 0.021
positive regulation of signaling GO:0023056 243 0.021
defense response GO:0006952 300 0.021
regulation of catabolic process GO:0009894 170 0.021
establishment or maintenance of cell polarity GO:0007163 167 0.021
protein complex biogenesis GO:0070271 201 0.021
regulation of mitotic cell cycle GO:0007346 190 0.021
regulation of organelle organization GO:0033043 196 0.021
spermatogenesis GO:0007283 200 0.021
gene silencing GO:0016458 138 0.021
salivary gland development GO:0007431 162 0.020
cell cycle phase transition GO:0044770 140 0.020
organelle assembly GO:0070925 198 0.020
eye morphogenesis GO:0048592 260 0.020
response to external biotic stimulus GO:0043207 293 0.020
imaginal disc derived wing hair organization GO:0035317 45 0.020
regulation of molecular function GO:0065009 217 0.019
negative regulation of cellular metabolic process GO:0031324 382 0.019
regulation of phosphate metabolic process GO:0019220 210 0.019
regulation of localization GO:0032879 275 0.019
compound eye morphogenesis GO:0001745 249 0.019
macromolecular complex assembly GO:0065003 256 0.019
photoreceptor cell differentiation GO:0046530 170 0.019
heterocycle catabolic process GO:0046700 166 0.018
regulation of proteolysis GO:0030162 87 0.018
eye development GO:0001654 323 0.018
mrna processing GO:0006397 104 0.018
regulation of cell cycle phase transition GO:1901987 130 0.018
aromatic compound catabolic process GO:0019439 166 0.018
regulation of organ morphogenesis GO:2000027 78 0.018
intracellular signal transduction GO:0035556 300 0.018
intracellular transport GO:0046907 228 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.017
response to abiotic stimulus GO:0009628 341 0.017
positive regulation of cellular catabolic process GO:0031331 95 0.017
hair cell differentiation GO:0035315 47 0.017
organic substance transport GO:0071702 257 0.017
organonitrogen compound metabolic process GO:1901564 318 0.017
embryo development ending in birth or egg hatching GO:0009792 152 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.017
response to other organism GO:0051707 293 0.017
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
defense response to other organism GO:0098542 225 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.016
cell death GO:0008219 279 0.016
cellular component assembly involved in morphogenesis GO:0010927 151 0.016
phosphorylation GO:0016310 294 0.016
positive regulation of catabolic process GO:0009896 105 0.016
positive regulation of molecular function GO:0044093 136 0.016
single organism catabolic process GO:0044712 228 0.016
modification dependent macromolecule catabolic process GO:0043632 79 0.016
response to organic substance GO:0010033 284 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
regulation of cell morphogenesis GO:0022604 163 0.016
lateral inhibition GO:0046331 206 0.016
positive regulation of endopeptidase activity GO:0010950 26 0.016
negative regulation of gene expression GO:0010629 387 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.015
response to bacterium GO:0009617 198 0.015
proteasomal protein catabolic process GO:0010498 59 0.015
response to biotic stimulus GO:0009607 294 0.015
regulation of mitotic cell cycle phase transition GO:1901990 130 0.015
cell migration GO:0016477 238 0.015
establishment of protein localization GO:0045184 163 0.015
germarium derived egg chamber formation GO:0007293 101 0.015
eye photoreceptor cell differentiation GO:0001754 145 0.015
regulation of gene expression epigenetic GO:0040029 128 0.015
compound eye photoreceptor cell differentiation GO:0001751 140 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
positive regulation of hydrolase activity GO:0051345 78 0.015
positive regulation of proteolysis GO:0045862 52 0.015
central nervous system development GO:0007417 201 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
ovarian follicle cell development GO:0030707 248 0.015
cellular protein catabolic process GO:0044257 83 0.015
ion transport GO:0006811 145 0.015
organic acid metabolic process GO:0006082 103 0.015
protein localization GO:0008104 284 0.015
male gamete generation GO:0048232 201 0.014
cytoplasmic transport GO:0016482 130 0.014
spindle organization GO:0007051 253 0.014
cell motility GO:0048870 251 0.014
digestive system development GO:0055123 149 0.014
eggshell chorion assembly GO:0007306 66 0.014
response to lipopolysaccharide GO:0032496 4 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
tube morphogenesis GO:0035239 191 0.014
epidermis development GO:0008544 65 0.014
response to copper ion GO:0046688 4 0.014
regulation of programmed cell death GO:0043067 152 0.014
protein transport GO:0015031 155 0.014
tube development GO:0035295 244 0.014
regulation of cell division GO:0051302 72 0.014
chromosome organization GO:0051276 360 0.014
tripartite regional subdivision GO:0007351 103 0.014
rna processing GO:0006396 147 0.014
single organism intracellular transport GO:1902582 207 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
localization of cell GO:0051674 257 0.013
compound eye photoreceptor development GO:0042051 78 0.013
protein maturation GO:0051604 71 0.013
wound healing GO:0042060 75 0.013
establishment of monopolar cell polarity GO:0061162 15 0.013
negative regulation of cell cycle process GO:0010948 109 0.013
protein processing GO:0016485 68 0.013
death GO:0016265 284 0.013
chromosome segregation GO:0007059 157 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
multi organism behavior GO:0051705 175 0.013
protein catabolic process GO:0030163 101 0.013
cellular macromolecule localization GO:0070727 220 0.013
negative regulation of mitotic cell cycle GO:0045930 109 0.013
mrna metabolic process GO:0016071 124 0.013
response to wounding GO:0009611 94 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
exocrine system development GO:0035272 162 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
defense response to bacterium GO:0042742 178 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
aggressive behavior GO:0002118 63 0.013
spermatid development GO:0007286 98 0.013
modification dependent protein catabolic process GO:0019941 78 0.013
cellular protein localization GO:0034613 160 0.012
protein phosphorylation GO:0006468 169 0.012
protein modification by small protein conjugation or removal GO:0070647 106 0.012
regulation of cytoskeleton organization GO:0051493 89 0.012
single organism biosynthetic process GO:0044711 206 0.012
response to oxygen containing compound GO:1901700 200 0.012
gene silencing by rna GO:0031047 57 0.012
wnt signaling pathway GO:0016055 98 0.012
eggshell formation GO:0030703 105 0.012
spermatid differentiation GO:0048515 114 0.012
negative regulation of cell cycle phase transition GO:1901988 103 0.012
regulation of developmental growth GO:0048638 174 0.012
carboxylic acid metabolic process GO:0019752 92 0.012
regulation of mrna metabolic process GO:1903311 72 0.012
photoreceptor cell development GO:0042461 96 0.012
regulation of phosphorylation GO:0042325 147 0.012
skin development GO:0043588 65 0.012
synaptic transmission GO:0007268 288 0.012
synapse organization GO:0050808 196 0.012
eye photoreceptor cell development GO:0042462 81 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.012
regulation of hydrolase activity GO:0051336 97 0.011
spinal cord development GO:0021510 1 0.011
oxoacid metabolic process GO:0043436 103 0.011
endomembrane system organization GO:0010256 119 0.011
dorsal closure GO:0007391 79 0.011
programmed cell death GO:0012501 257 0.011
small molecule metabolic process GO:0044281 305 0.011
positive regulation of organelle organization GO:0010638 65 0.011
retina development in camera type eye GO:0060041 4 0.011
cuticle development GO:0042335 86 0.011
regulation of response to stress GO:0080134 200 0.011
positive regulation of gene expression GO:0010628 290 0.011
negative regulation of signaling GO:0023057 219 0.011
regulation of cell death GO:0010941 173 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
embryonic pattern specification GO:0009880 174 0.011
oocyte construction GO:0007308 112 0.011
ubiquitin dependent protein catabolic process GO:0006511 78 0.011
ameboidal type cell migration GO:0001667 151 0.011
cell recognition GO:0008037 102 0.011
regulation of mrna processing GO:0050684 71 0.011
regulation of apoptotic process GO:0042981 130 0.011
response to organonitrogen compound GO:0010243 75 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
negative regulation of cell communication GO:0010648 223 0.011
chaeta development GO:0022416 97 0.010
developmental growth GO:0048589 280 0.010
camera type eye development GO:0043010 4 0.010
positive regulation of peptidase activity GO:0010952 29 0.010
regulation of intracellular signal transduction GO:1902531 236 0.010
salivary gland morphogenesis GO:0007435 145 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
negative regulation of signal transduction GO:0009968 206 0.010
regulation of transport GO:0051049 181 0.010
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.010
cell cell junction organization GO:0045216 55 0.010
gland morphogenesis GO:0022612 145 0.010
regulation of cell shape GO:0008360 113 0.010
negative regulation of biosynthetic process GO:0009890 277 0.010
response to oxidative stress GO:0006979 86 0.010
epidermal growth factor receptor signaling pathway GO:0007173 58 0.010
protein ubiquitination GO:0016567 70 0.010
immune response GO:0006955 246 0.010

Alg-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.015
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.013
inherited metabolic disorder DOID:655 0 0.012