Drosophila melanogaster

22 known processes

18w (Dmel_CG8896)

18 wheeler

(Aliases: l(2)00053,tlr,CG8896,Dmel\CG8896,CT25100,18-wheeler,18W,toll)

18w biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.806
Mouse
defense response to virus GO:0051607 23 0.788
Human Mouse
positive regulation of transcription dna templated GO:0045893 266 0.758
Mouse
activation of innate immune response GO:0002218 4 0.698
Human Mouse
regulation of nf kappab import into nucleus GO:0042345 1 0.672
Human
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.662
Human Mouse
antibacterial humoral response GO:0019731 44 0.646
positive regulation of nf kappab import into nucleus GO:0042346 1 0.636
Human
cell proliferation GO:0008283 299 0.602
Fly
maintenance of gastrointestinal epithelium GO:0030277 3 0.547
Mouse
negative regulation of rna metabolic process GO:0051253 251 0.508
response to virus GO:0009615 28 0.496
Human Zebrafish Mouse
immune system process GO:0002376 347 0.488
cellular response to abiotic stimulus GO:0071214 58 0.471
Human
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.449
dorsal ventral pattern formation GO:0009953 133 0.430
Fly
nf kappab import into nucleus GO:0042348 1 0.416
Human
regulation of multi organism process GO:0043900 131 0.401
Fly
kidney epithelium development GO:0072073 3 0.380
negative regulation of cell proliferation GO:0008285 69 0.371
positive regulation of rna metabolic process GO:0051254 271 0.363
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.348
positive regulation of transcription factor import into nucleus GO:0042993 19 0.342
Human
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.338
regionalization GO:0003002 416 0.326
Fly
i kappab phosphorylation GO:0007252 3 0.325
Human
nephron development GO:0072006 3 0.322
tissue morphogenesis GO:0048729 297 0.316
transcription from rna polymerase ii promoter GO:0006366 368 0.314
Mouse
cellular response to external stimulus GO:0071496 66 0.314
Human
positive regulation of biosynthetic process GO:0009891 316 0.311
Human Mouse Fly
negative regulation of multicellular organismal process GO:0051241 142 0.310
Mouse
negative regulation of cellular biosynthetic process GO:0031327 277 0.306
negative regulation of transcription dna templated GO:0045892 237 0.301
positive regulation of cellular biosynthetic process GO:0031328 316 0.298
Human Mouse Fly
negative regulation of gene expression GO:0010629 387 0.284
epithelial structure maintenance GO:0010669 17 0.284
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 240 0.280
regulation of defense response to virus GO:0050688 14 0.275
neuron projection guidance GO:0097485 241 0.265
positive regulation of nucleic acid templated transcription GO:1903508 266 0.263
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.262
Mouse
cellular response to mechanical stimulus GO:0071260 2 0.259
Human
regulation of multicellular organismal development GO:2000026 414 0.254
kidney development GO:0001822 3 0.253
nephron morphogenesis GO:0072028 3 0.252
response to nitrogen compound GO:1901698 90 0.246
Human Mouse
retina development in camera type eye GO:0060041 4 0.242
regulation of immune effector process GO:0002697 52 0.239
Fly
cell division GO:0051301 248 0.238
Fly
apoptotic process GO:0006915 159 0.222
Human
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.222
Mouse
sensory organ morphogenesis GO:0090596 260 0.222
regulation of cellular response to stress GO:0080135 89 0.212
Mouse
positive regulation of multicellular organismal process GO:0051240 143 0.206
Human Mouse
peptide metabolic process GO:0006518 80 0.205
Fly
regulation of response to wounding GO:1903034 19 0.199
Mouse
nephron epithelium development GO:0072009 3 0.195
programmed cell death GO:0012501 257 0.193
Human
immune response activating signal transduction GO:0002757 2 0.193
Human Mouse
regulation of cell proliferation GO:0042127 163 0.190
response to dsrna GO:0043331 15 0.188
Human Mouse
wing disc morphogenesis GO:0007472 344 0.187
connective tissue development GO:0061448 3 0.176
negative regulation of signaling GO:0023057 219 0.175
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.172
Mouse Fly
appendage morphogenesis GO:0035107 397 0.171
forebrain development GO:0030900 2 0.170
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.169
Human Mouse
neural retina development GO:0003407 4 0.167
regulation of response to biotic stimulus GO:0002831 63 0.163
Fly
nephron tubule morphogenesis GO:0072078 3 0.162
cellular protein localization GO:0034613 160 0.160
Human
negative regulation of biosynthetic process GO:0009890 277 0.157
tissue homeostasis GO:0001894 36 0.156
Mouse
humoral immune response GO:0006959 117 0.156
positive regulation of gene expression GO:0010628 290 0.154
Mouse
immune effector process GO:0002252 98 0.140
Human Mouse Fly
phosphorylation GO:0016310 294 0.140
Human Mouse
multicellular organismal reproductive behavior GO:0033057 110 0.137
regulation of response to stress GO:0080134 200 0.136
Human Mouse Fly
response to wounding GO:0009611 94 0.135
Mouse
protein localization GO:0008104 284 0.134
Human
extrinsic apoptotic signaling pathway GO:0097191 1 0.134
Human
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.134
spinal cord dorsal ventral patterning GO:0021513 1 0.134
response to external biotic stimulus GO:0043207 293 0.132
camera type eye development GO:0043010 4 0.132
ion transport GO:0006811 145 0.131
spinal cord patterning GO:0021511 1 0.128
camera type eye morphogenesis GO:0048593 2 0.126
dorsal ventral axis specification GO:0009950 66 0.126
Fly
cellular macromolecule localization GO:0070727 220 0.125
Human
taxis GO:0042330 304 0.125
Fly
cell death GO:0008219 279 0.121
Human
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.119
Fly
kidney morphogenesis GO:0060993 3 0.115
regulation of cell cycle phase transition GO:1901987 130 0.114
positive regulation of rna biosynthetic process GO:1902680 266 0.114
Mouse
positive regulation of antimicrobial humoral response GO:0002760 28 0.114
Fly
establishment of protein localization GO:0045184 163 0.114
Human
single organism cellular localization GO:1902580 180 0.113
Human
imaginal disc pattern formation GO:0007447 91 0.112
anatomical structure homeostasis GO:0060249 97 0.109
Mouse
multi multicellular organism process GO:0044706 123 0.107
segmentation GO:0035282 207 0.107
axon guidance GO:0007411 233 0.107
single organism behavior GO:0044708 391 0.106
post embryonic appendage morphogenesis GO:0035120 385 0.106
protein complex localization GO:0031503 4 0.104
Human
positive regulation of antifungal peptide biosynthetic process GO:0006967 5 0.102
Fly
positive regulation of humoral immune response GO:0002922 28 0.101
Fly
regulation of epithelial cell proliferation GO:0050678 4 0.099
antifungal peptide biosynthetic process GO:0002783 5 0.097
Fly
positive regulation of signaling GO:0023056 243 0.096
Human Mouse
regulation of production of molecular mediator of immune response GO:0002700 44 0.095
Fly
axonogenesis GO:0007409 290 0.095
eye development GO:0001654 323 0.094
developmental growth GO:0048589 280 0.092
equator specification GO:0045317 4 0.090
positive regulation of macromolecule metabolic process GO:0010604 405 0.090
Human Mouse
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.090
Human Mouse
muscle organ development GO:0007517 127 0.089
regulation of antifungal peptide biosynthetic process GO:0002810 5 0.088
Fly
negative regulation of response to stimulus GO:0048585 258 0.086
cardiovascular system development GO:0072358 82 0.085
Fly
rhythmic process GO:0048511 106 0.084
heart development GO:0007507 82 0.084
Fly
embryonic organ development GO:0048568 50 0.084
limb development GO:0060173 1 0.082
regulation of cell cycle GO:0051726 291 0.082
nephron tubule development GO:0072080 3 0.082
imaginal disc derived appendage morphogenesis GO:0035114 395 0.081
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.081
positive regulation of multi organism process GO:0043902 40 0.081
Fly
cellular protein modification process GO:0006464 438 0.080
Human Fly
negative regulation of binding GO:0051100 5 0.080
regulation of immune response GO:0050776 118 0.079
Human Mouse Fly
epithelial cell differentiation GO:0030855 322 0.078
retina morphogenesis in camera type eye GO:0060042 2 0.078
negative regulation of developmental process GO:0051093 201 0.078
leucine transport GO:0015820 3 0.078
positive regulation of antimicrobial peptide production GO:0002225 28 0.077
Fly
organic substance transport GO:0071702 257 0.076
Human
regulation of antifungal peptide production GO:0002788 6 0.076
Fly
ion transmembrane transport GO:0034220 122 0.075
circadian rhythm GO:0007623 105 0.074
response to organic cyclic compound GO:0014070 89 0.073
Human Mouse
muscle structure development GO:0061061 224 0.073
morphogenesis of an epithelium GO:0002009 276 0.072
negative regulation of cellular metabolic process GO:0031324 382 0.071
appendage development GO:0048736 401 0.071
regulation of developmental growth GO:0048638 174 0.070
regulation of cell death GO:0010941 173 0.068
embryonic morphogenesis GO:0048598 206 0.068
death GO:0016265 284 0.068
Human
intracellular signal transduction GO:0035556 300 0.067
Human Mouse
cell maturation GO:0048469 144 0.066
establishment of localization in cell GO:0051649 402 0.065
Human
light adaption GO:0036367 3 0.065
regulation of protein transport GO:0051223 57 0.065
Human
periodic partitioning GO:0007365 29 0.062
regulation of organ morphogenesis GO:2000027 78 0.062
cellular response to dna damage stimulus GO:0006974 223 0.061
protein localization to organelle GO:0033365 82 0.061
Human
regulation of innate immune response GO:0045088 71 0.060
Human Mouse
regulation of molecular function GO:0065009 217 0.060
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.060
regulation of phosphorylation GO:0042325 147 0.059
Mouse
regulation of programmed cell death GO:0043067 152 0.059
positive regulation of intracellular signal transduction GO:1902533 116 0.058
Human Mouse
regulation of cellular protein metabolic process GO:0032268 243 0.058
Fly
immune response regulating signaling pathway GO:0002764 2 0.056
Human Mouse
proximal distal pattern formation GO:0009954 15 0.056
compound eye morphogenesis GO:0001745 249 0.055
cellular amide metabolic process GO:0043603 80 0.054
Fly
positive regulation of defense response GO:0031349 59 0.054
Human Mouse Fly
response to endogenous stimulus GO:0009719 119 0.054
innate immune response in mucosa GO:0002227 2 0.053
Fly
ectodermal placode morphogenesis GO:0071697 4 0.053
segment specification GO:0007379 33 0.052
developmental maturation GO:0021700 172 0.052
axon development GO:0061564 297 0.051
locomotory behavior GO:0007626 176 0.051
endocytosis GO:0006897 310 0.051
antibacterial peptide biosynthetic process GO:0002780 22 0.051
Fly
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.051
negative regulation of signal transduction GO:0009968 206 0.051
defense response to other organism GO:0098542 225 0.051
eye morphogenesis GO:0048592 260 0.050
positive regulation of transport GO:0051050 92 0.049
Human
positive regulation of protein metabolic process GO:0051247 128 0.049
Human Mouse
nephron epithelium morphogenesis GO:0072088 3 0.048
regulation of localization GO:0032879 275 0.048
Human
imaginal disc derived appendage development GO:0048737 399 0.048
limb morphogenesis GO:0035108 1 0.048
positive regulation of antifungal peptide production GO:0002804 6 0.047
Fly
anion transport GO:0006820 41 0.047
innate immune response GO:0045087 144 0.047
Mouse Fly
spinal cord development GO:0021510 1 0.047
stem cell differentiation GO:0048863 117 0.046
antimicrobial humoral response GO:0019730 99 0.046
regulation of transport GO:0051049 181 0.046
Human
negative regulation of apoptotic process GO:0043066 63 0.045
mesenchymal cell differentiation GO:0048762 1 0.045
regulation of protein localization GO:0032880 76 0.043
Human
regulation of defense response GO:0031347 102 0.043
Human Mouse Fly
regulation of epithelial cell differentiation GO:0030856 4 0.043
protein transport GO:0015031 155 0.042
Human
telencephalon development GO:0021537 2 0.042
detection of stimulus involved in sensory perception GO:0050906 92 0.041
cellular response to chemical stimulus GO:0070887 199 0.040
regulation of circadian rhythm GO:0042752 49 0.040
rna interference GO:0016246 27 0.040
pattern recognition receptor signaling pathway GO:0002221 2 0.040
Human Mouse
positive regulation of cellular amide metabolic process GO:0034250 26 0.039
Fly
biological adhesion GO:0022610 138 0.039
monocarboxylic acid transport GO:0015718 3 0.039
innate immune response activating signal transduction GO:0002758 2 0.039
Human Mouse
chromatin modification GO:0016568 147 0.039
regulation of mitotic cell cycle GO:0007346 190 0.038
response to mechanical stimulus GO:0009612 28 0.038
Human
regulation of antimicrobial humoral response GO:0002759 50 0.038
Fly
regulation of intracellular signal transduction GO:1902531 236 0.038
Human Mouse
developmental programmed cell death GO:0010623 138 0.037
adult behavior GO:0030534 137 0.037
ectodermal placode development GO:0071696 4 0.037
negative regulation of protein metabolic process GO:0051248 85 0.037
vesicle mediated transport GO:0016192 381 0.037
regulation of sequence specific dna binding transcription factor activity GO:0051090 12 0.036
Mouse
heart morphogenesis GO:0003007 32 0.036
protein localization to nucleus GO:0034504 55 0.036
Human
positive regulation of response to stimulus GO:0048584 323 0.035
Human Mouse Fly
carboxylic acid transport GO:0046942 18 0.035
renal system development GO:0072001 72 0.035
single organism carbohydrate metabolic process GO:0044723 72 0.035
Fly
positive regulation of response to biotic stimulus GO:0002833 31 0.034
Fly
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.034
ectodermal placode formation GO:0060788 4 0.034
adult locomotory behavior GO:0008344 76 0.034
compound eye development GO:0048749 307 0.034
positive regulation of developmental process GO:0051094 143 0.033
wnt signaling pathway GO:0016055 98 0.033
regulation of imaginal disc growth GO:0045570 26 0.033
chromatin organization GO:0006325 207 0.033
cell cycle phase transition GO:0044770 140 0.032
phagocytosis GO:0006909 215 0.032
body morphogenesis GO:0010171 2 0.031
Worm
negative regulation of cell cycle GO:0045786 116 0.031
glycoprotein metabolic process GO:0009100 41 0.031
Fly
positive regulation of immune effector process GO:0002699 28 0.031
Fly
positive regulation of cell proliferation GO:0008284 47 0.031
wing disc pattern formation GO:0035222 66 0.031
rna processing GO:0006396 147 0.031
positive regulation of protein transport GO:0051222 37 0.030
Human
dendrite morphogenesis GO:0048813 199 0.030
antimicrobial peptide production GO:0002775 46 0.030
Fly
regulation of antimicrobial peptide production GO:0002784 44 0.030
Fly
positive regulation of phosphorylation GO:0042327 87 0.029
Mouse
chromatin silencing GO:0006342 76 0.029
cell cell signaling involved in cell fate commitment GO:0045168 210 0.029
regulation of rna splicing GO:0043484 69 0.029
regulation of defense response to bacterium GO:1900424 30 0.028
Fly
organ or tissue specific immune response GO:0002251 10 0.028
Fly
skeletal muscle organ development GO:0060538 48 0.028
smoothened signaling pathway GO:0007224 49 0.027
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.027
regulation of protein metabolic process GO:0051246 256 0.027
Human Mouse Fly
imaginal disc derived wing morphogenesis GO:0007476 337 0.027
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.027
Fly
response to ethanol GO:0045471 59 0.026
positive regulation of protein localization to nucleus GO:1900182 21 0.026
Human
response to alcohol GO:0097305 95 0.026
organelle fission GO:0048285 340 0.026
regulation of cellular amine metabolic process GO:0033238 3 0.026
gland morphogenesis GO:0022612 145 0.026
striated muscle tissue development GO:0014706 27 0.026
regulation of wnt signaling pathway GO:0030111 68 0.026
mrna splicing via spliceosome GO:0000398 73 0.025
segment polarity determination GO:0007367 25 0.025
cellular response to organic substance GO:0071310 132 0.025
tube development GO:0035295 244 0.025
response to abiotic stimulus GO:0009628 341 0.025
Human
sulfur compound metabolic process GO:0006790 59 0.024
immune response GO:0006955 246 0.024
entrainment of circadian clock GO:0009649 16 0.024
cell migration GO:0016477 238 0.024
regulation of establishment of protein localization GO:0070201 61 0.023
Human
epithelial cell morphogenesis involved in gastrulation GO:0003381 7 0.023
protein modification process GO:0036211 438 0.023
Human Fly
intracellular transport GO:0046907 228 0.023
Human
amide biosynthetic process GO:0043604 42 0.023
Fly
stress activated protein kinase signaling cascade GO:0031098 55 0.023
Mouse
negative regulation of cellular protein metabolic process GO:0032269 85 0.023
positive regulation of protein import into nucleus GO:0042307 21 0.023
Human
negative regulation of epithelial cell proliferation GO:0050680 4 0.022
symbiosis encompassing mutualism through parasitism GO:0044403 16 0.022
cell cycle arrest GO:0007050 4 0.022
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.022
regulation of carbohydrate metabolic process GO:0006109 10 0.022
Fly
stem cell proliferation GO:0072089 88 0.022
homeostatic process GO:0042592 199 0.022
Mouse
signal transduction in response to dna damage GO:0042770 3 0.022
dendrite development GO:0016358 204 0.021
negative regulation of mitotic cell cycle GO:0045930 109 0.021
imaginal disc derived leg segmentation GO:0036011 26 0.021
regulation of mitotic cell cycle phase transition GO:1901990 130 0.021
regulation of jnk cascade GO:0046328 40 0.021
Mouse
protein targeting GO:0006605 64 0.021
Human
signal transduction by p53 class mediator GO:0072331 6 0.021
positive regulation of signal transduction GO:0009967 223 0.021
Human Mouse
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.021
protein phosphorylation GO:0006468 169 0.021
Human
carbohydrate metabolic process GO:0005975 82 0.020
Fly
negative regulation of cell death GO:0060548 81 0.020
regulation of humoral immune response GO:0002920 51 0.020
Fly
necrotic cell death GO:0070265 1 0.020
Human
non sensory hair organization GO:0035316 47 0.020
production of molecular mediator of immune response GO:0002440 46 0.020
Fly
outflow tract morphogenesis GO:0003151 4 0.020
positive regulation of intracellular transport GO:0032388 42 0.020
Human
regulation of cell cycle process GO:0010564 181 0.020
imaginal disc derived leg morphogenesis GO:0007480 80 0.020
cytokinesis GO:0000910 90 0.019
Fly
positive regulation of stem cell differentiation GO:2000738 3 0.019
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.019
regulation of response to dna damage stimulus GO:2001020 23 0.019
protein complex assembly GO:0006461 200 0.019
membrane organization GO:0061024 112 0.019
response to other organism GO:0051707 293 0.019
negative regulation of imaginal disc growth GO:0045571 8 0.019
single organism nuclear import GO:1902593 51 0.019
Human
mesenchymal cell development GO:0014031 1 0.019
response to light stimulus GO:0009416 124 0.019
respiratory system development GO:0060541 213 0.018
embryonic heart tube development GO:0035050 22 0.018
cellular response to organonitrogen compound GO:0071417 36 0.018
single organism intracellular transport GO:1902582 207 0.018
Human
posttranscriptional regulation of gene expression GO:0010608 145 0.018
digestive system development GO:0055123 149 0.018
lateral inhibition GO:0046331 206 0.018
negative regulation of cell cycle phase transition GO:1901988 103 0.018
regulation of catalytic activity GO:0050790 185 0.018
optic placode formation GO:0001743 4 0.018
salivary gland development GO:0007431 162 0.018
response to organic substance GO:0010033 284 0.018
Human Mouse
epidermal cell differentiation GO:0009913 51 0.018
regulation of phosphate metabolic process GO:0019220 210 0.017
Mouse
regulation of anatomical structure morphogenesis GO:0022603 242 0.017
establishment of body hair planar orientation GO:0048105 1 0.017
synapse organization GO:0050808 196 0.017
Fly
i kappab kinase nf kappab signaling GO:0007249 6 0.017
Human Mouse
basement membrane organization GO:0071711 10 0.017
glycoprotein biosynthetic process GO:0009101 41 0.017
Fly
negative regulation of stem cell proliferation GO:2000647 30 0.017
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.017
regulation of intracellular protein transport GO:0033157 46 0.017
Human
positive regulation of cell cycle process GO:0090068 28 0.017
establishment of protein localization to organelle GO:0072594 62 0.017
Human
negative regulation of cell cycle process GO:0010948 109 0.017
response to organophosphorus GO:0046683 2 0.017
bmp signaling pathway involved in malpighian tubule cell chemotaxis GO:0061353 3 0.016
protein processing GO:0016485 68 0.016
cation transmembrane transport GO:0098655 88 0.016
regulation of immune system process GO:0002682 176 0.016
Human Mouse Fly
regulation of organelle organization GO:0033043 196 0.016
embryonic organ morphogenesis GO:0048562 5 0.016
adipose tissue development GO:0060612 2 0.016
negative regulation of multi organism process GO:0043901 29 0.016
mucosal immune response GO:0002385 10 0.015
Fly
imaginal disc growth GO:0007446 37 0.015
negative regulation of programmed cell death GO:0043069 72 0.015
rna splicing via transesterification reactions GO:0000375 73 0.015
muscle tissue development GO:0060537 30 0.015
compound eye photoreceptor cell differentiation GO:0001751 140 0.015
hindbrain development GO:0030902 2 0.015
developmental pigmentation GO:0048066 68 0.015
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.015
regulation of cell development GO:0060284 215 0.015
chromatin remodeling GO:0006338 72 0.015
positive regulation of cell motility GO:2000147 3 0.015
regulation of protein localization to nucleus GO:1900180 29 0.015
Human
regulation of neuroblast proliferation GO:1902692 34 0.015
lipid localization GO:0010876 54 0.015
neuron recognition GO:0008038 101 0.015
Fly
growth GO:0040007 359 0.015
cell recognition GO:0008037 102 0.014
Fly
wound healing GO:0042060 75 0.014
oxoacid metabolic process GO:0043436 103 0.014
alternative mrna splicing via spliceosome GO:0000380 60 0.014
imaginal disc derived leg joint morphogenesis GO:0016348 15 0.014
circulatory system development GO:0072359 82 0.014
Fly
negative regulation of cell communication GO:0010648 223 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
regulation of meiosis GO:0040020 3 0.014
head development GO:0060322 135 0.014
phasic smooth muscle contraction GO:0014821 1 0.014
skeletal muscle fiber development GO:0048741 3 0.014
regulation of chromatin silencing GO:0031935 36 0.014
jnk cascade GO:0007254 50 0.014
Mouse
myotube cell development GO:0014904 3 0.014
regulation of mapk cascade GO:0043408 92 0.014
Mouse
posttranscriptional gene silencing GO:0016441 46 0.014
cellular response to hormone stimulus GO:0032870 44 0.014
male gamete generation GO:0048232 201 0.014
chromosome organization GO:0051276 360 0.014
rna splicing GO:0008380 83 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
embryonic pattern specification GO:0009880 174 0.013
synapse assembly GO:0007416 143 0.013
Fly
central nervous system development GO:0007417 201 0.013
regulation of heart morphogenesis GO:2000826 3 0.013
negative regulation of nervous system development GO:0051961 92 0.013
intracellular protein transport GO:0006886 104 0.013
Human
chromatin mediated maintenance of transcription GO:0048096 7 0.013
secretion GO:0046903 109 0.013
protein import GO:0017038 55 0.013
Human
positive regulation of stress activated mapk cascade GO:0032874 17 0.013
Mouse
genital disc pattern formation GO:0035221 8 0.013
negative regulation of cell differentiation GO:0045596 143 0.013
myotube differentiation GO:0014902 46 0.013
phosphatidylinositol phosphorylation GO:0046854 10 0.013
cellular homeostasis GO:0019725 80 0.013
leg disc development GO:0035218 92 0.013
positive regulation of ion transmembrane transporter activity GO:0032414 4 0.013
catabolic process GO:0009056 409 0.013
salivary gland morphogenesis GO:0007435 145 0.012
nuclear transport GO:0051169 72 0.012
Human
organ formation GO:0048645 39 0.012
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 15 0.012
establishment of planar polarity GO:0001736 87 0.012
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 9 0.012
Mouse
sex differentiation GO:0007548 81 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.012
Mouse
cellular response to amino acid stimulus GO:0071230 6 0.012
regulation of defense response to fungus GO:1900150 6 0.012
Fly
chemotaxis GO:0006935 249 0.012
Fly
negative regulation of neurogenesis GO:0050768 53 0.012
positive regulation of innate immune response GO:0045089 38 0.012
Human Mouse
regulation of reproductive process GO:2000241 54 0.012
larval development GO:0002164 104 0.012
Worm
neurological system process GO:0050877 358 0.012
cranial nerve development GO:0021545 1 0.012
negative regulation of molecular function GO:0044092 51 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
reproductive structure development GO:0048608 74 0.012
regulation of cellular localization GO:0060341 136 0.012
Human
synaptic target recognition GO:0008039 45 0.012
Fly
photoreceptor cell differentiation GO:0046530 170 0.012
regulation of mrna metabolic process GO:1903311 72 0.012
autophagic cell death GO:0048102 83 0.012
pharynx development GO:0060465 1 0.012
optic lobe placode formation GO:0001744 4 0.011
endomembrane system organization GO:0010256 119 0.011
cell surface receptor signaling pathway involved in heart development GO:0061311 3 0.011
mitochondrial fission GO:0000266 8 0.011
neuron maturation GO:0042551 31 0.011
renal tubule development GO:0061326 64 0.011
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.011
Human
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.011
cellular response to monosaccharide stimulus GO:0071326 2 0.011
positive regulation of epithelial cell differentiation GO:0030858 1 0.011
regulation of stem cell proliferation GO:0072091 40 0.011
cell adhesion GO:0007155 136 0.011
cytoplasmic transport GO:0016482 130 0.011
Human
endocrine system development GO:0035270 5 0.011
wing disc dorsal ventral pattern formation GO:0048190 47 0.011
regulation of bmp signaling pathway GO:0030510 23 0.011
regulation of mrna splicing via spliceosome GO:0048024 64 0.011
positive regulation of cell cycle GO:0045787 43 0.011
response to drug GO:0042493 17 0.011
male gonad development GO:0008584 9 0.011
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.011
regulation of stress activated mapk cascade GO:0032872 41 0.011
Mouse
regulation of neural precursor cell proliferation GO:2000177 35 0.011
positive regulation of developmental growth GO:0048639 62 0.011
response to hypoxia GO:0001666 53 0.011
positive regulation of programmed cell death GO:0043068 62 0.011
positive regulation of immune response GO:0050778 63 0.010
Human Mouse Fly
macromolecule glycosylation GO:0043413 32 0.010
Fly
positive regulation of cell migration GO:0030335 2 0.010
regulation of cell junction assembly GO:1901888 2 0.010
amine metabolic process GO:0009308 12 0.010
signal transduction by phosphorylation GO:0023014 107 0.010
Mouse
striated muscle cell differentiation GO:0051146 90 0.010
response to bacterium GO:0009617 198 0.010

18w disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
sensory system disease DOID:0050155 0 0.021
eye and adnexa disease DOID:1492 0 0.021
nervous system disease DOID:863 0 0.021
cardiovascular system disease DOID:1287 0 0.017
cancer DOID:162 0 0.017
disease of cellular proliferation DOID:14566 0 0.017
organ system cancer DOID:0050686 0 0.017
bone disease DOID:0080001 0 0.016
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.016
bone development disease DOID:0080006 0 0.013