Drosophila melanogaster

101 known processes

ball (Dmel_CG6386)

ballchen

(Aliases: Dmel\CG6386,Ball,NHK-1,trip,BcDNA:LD09009,NHK1,BALL,CG6386,VRK,nhk-1)

ball biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle fission GO:0048285 340 0.996
meiotic cell cycle GO:0051321 171 0.994
mitotic spindle organization GO:0007052 220 0.993
sister chromatid segregation GO:0000819 92 0.991
meiotic nuclear division GO:0007126 151 0.984
meiotic cell cycle process GO:1903046 132 0.983
chromosome organization GO:0051276 360 0.950
nuclear division GO:0000280 332 0.939
spindle organization GO:0007051 253 0.938
meiosis i GO:0007127 59 0.937
male meiosis GO:0007140 52 0.844
mitotic sister chromatid segregation GO:0000070 87 0.832
microtubule organizing center organization GO:0031023 168 0.804
spindle assembly GO:0051225 80 0.730
meiotic chromosome segregation GO:0045132 59 0.721
chromosome segregation GO:0007059 157 0.710
cell proliferation GO:0008283 299 0.692
karyosome formation GO:0030717 22 0.687
mitotic nuclear division GO:0007067 213 0.675
mitotic chromosome condensation GO:0007076 22 0.624
spindle assembly involved in mitosis GO:0090307 50 0.545
gene silencing GO:0016458 138 0.530
cell division GO:0051301 248 0.502
cellular macromolecular complex assembly GO:0034622 153 0.486
dna conformation change GO:0071103 105 0.450
oocyte differentiation GO:0009994 145 0.426
regulation of organelle organization GO:0033043 196 0.396
dna packaging GO:0006323 91 0.388
chromosome condensation GO:0030261 41 0.367
mitotic sister chromatid separation GO:0051306 30 0.343
metaphase plate congression GO:0051310 19 0.342
male gamete generation GO:0048232 201 0.318
mitotic spindle elongation GO:0000022 81 0.291
macromolecular complex assembly GO:0065003 256 0.283
spindle midzone assembly GO:0051255 4 0.280
establishment of organelle localization GO:0051656 122 0.278
dna metabolic process GO:0006259 227 0.251
female meiotic division GO:0007143 70 0.236
positive regulation of cellular component organization GO:0051130 156 0.225
protein complex biogenesis GO:0070271 201 0.221
regulation of mitotic spindle organization GO:0060236 9 0.217
establishment of spindle orientation GO:0051294 18 0.211
cellular protein modification process GO:0006464 438 0.197
microtubule polymerization or depolymerization GO:0031109 39 0.193
germarium derived egg chamber formation GO:0007293 101 0.180
meiotic spindle organization GO:0000212 36 0.175
organelle assembly GO:0070925 198 0.173
dna recombination GO:0006310 32 0.172
negative regulation of cellular biosynthetic process GO:0031327 277 0.172
organelle localization GO:0051640 148 0.170
protein modification process GO:0036211 438 0.167
centrosome organization GO:0051297 163 0.166
embryo development ending in birth or egg hatching GO:0009792 152 0.164
Worm
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.162
fertilization GO:0009566 26 0.157
mitotic spindle stabilization GO:0043148 6 0.154
posttranscriptional gene silencing by rna GO:0035194 45 0.150
regulation of microtubule based process GO:0032886 49 0.146
regulation of cellular protein metabolic process GO:0032268 243 0.140
gene silencing by rna GO:0031047 57 0.135
covalent chromatin modification GO:0016569 106 0.134
regulation of nuclear division GO:0051783 58 0.132
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.132
regulation of meiosis GO:0040020 3 0.129
catabolic process GO:0009056 409 0.121
spindle assembly involved in meiosis GO:0090306 20 0.121
double strand break repair via synthesis dependent strand annealing GO:0045003 6 0.115
mitotic spindle midzone assembly GO:0051256 1 0.114
nucleus localization GO:0051647 34 0.113
chromosome separation GO:0051304 42 0.109
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.108
regulation of chromosome organization GO:0033044 64 0.108
spindle stabilization GO:0043146 14 0.106
regulation of spindle organization GO:0090224 17 0.104
chromatin organization GO:0006325 207 0.104
regulation of catalytic activity GO:0050790 185 0.101
Mouse
pole cell formation GO:0007279 19 0.100
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.098
single organism biosynthetic process GO:0044711 206 0.097
regulation of cell division GO:0051302 72 0.096
positive regulation of phosphorus metabolic process GO:0010562 139 0.094
Mouse Fly
immune system process GO:0002376 347 0.092
centrosome cycle GO:0007098 137 0.089
cytoskeleton dependent cytokinesis GO:0061640 81 0.089
spermatogenesis GO:0007283 200 0.089
development of primary sexual characteristics GO:0045137 50 0.088
Worm
protein complex assembly GO:0006461 200 0.088
regulation of phosphate metabolic process GO:0019220 210 0.086
Human Mouse Fly
nucleobase containing compound catabolic process GO:0034655 165 0.084
positive regulation of catabolic process GO:0009896 105 0.082
meiotic sister chromatid segregation GO:0045144 6 0.081
regulation of cell cycle process GO:0010564 181 0.080
negative regulation of protein depolymerization GO:1901880 23 0.079
telomere maintenance via recombination GO:0000722 1 0.078
cellular macromolecule catabolic process GO:0044265 136 0.078
negative regulation of protein complex disassembly GO:0043242 23 0.077
regulation of protein complex disassembly GO:0043244 29 0.077
posttranscriptional gene silencing GO:0016441 46 0.075
negative regulation of cell cycle GO:0045786 116 0.074
organic substance catabolic process GO:1901575 308 0.072
protein dna complex subunit organization GO:0071824 86 0.071
positive regulation of phosphate metabolic process GO:0045937 139 0.070
Mouse Fly
regulation of cell cycle GO:0051726 291 0.070
regulation of proteasomal protein catabolic process GO:0061136 39 0.068
centrosome separation GO:0051299 20 0.068
regulation of mitosis GO:0007088 56 0.067
spindle assembly involved in female meiosis GO:0007056 14 0.066
meiosis ii GO:0007135 23 0.063
rna processing GO:0006396 147 0.063
homeostatic process GO:0042592 199 0.059
protein complex disassembly GO:0043241 36 0.058
aromatic compound catabolic process GO:0019439 166 0.057
cellular protein complex assembly GO:0043623 71 0.056
cell death GO:0008219 279 0.054
regulation of microtubule cytoskeleton organization GO:0070507 41 0.054
regulation of mitotic sister chromatid separation GO:0010965 28 0.053
female meiosis i GO:0007144 8 0.053
programmed cell death GO:0012501 257 0.052
ras protein signal transduction GO:0007265 88 0.052
Fly
establishment of cell polarity GO:0030010 40 0.052
mitotic centrosome separation GO:0007100 8 0.051
regulation of protein metabolic process GO:0051246 256 0.051
dendrite development GO:0016358 204 0.050
establishment of mitotic spindle orientation GO:0000132 13 0.050
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.049
negative regulation of gene expression GO:0010629 387 0.049
developmental maturation GO:0021700 172 0.048
negative regulation of rna biosynthetic process GO:1902679 240 0.047
peptidyl amino acid modification GO:0018193 105 0.047
oocyte construction GO:0007308 112 0.046
histone mrna metabolic process GO:0008334 8 0.045
pole cell development GO:0007277 26 0.045
cell fate determination GO:0001709 91 0.045
oocyte axis specification GO:0007309 108 0.044
regulation of small gtpase mediated signal transduction GO:0051056 93 0.042
Fly
cellular catabolic process GO:0044248 372 0.042
regulation of phosphorus metabolic process GO:0051174 210 0.041
Human Mouse Fly
male meiosis cytokinesis GO:0007112 26 0.041
histone modification GO:0016570 106 0.040
mrna metabolic process GO:0016071 124 0.040
regulation of localization GO:0032879 275 0.040
regulation of mitotic sister chromatid segregation GO:0033047 28 0.040
regulation of multicellular organismal development GO:2000026 414 0.040
regulation of protein modification process GO:0031399 112 0.039
regulation of gene expression epigenetic GO:0040029 128 0.039
regulation of meiotic cell cycle GO:0051445 9 0.037
regulation of gene silencing GO:0060968 63 0.037
regulation of chromatin organization GO:1902275 32 0.037
oocyte development GO:0048599 124 0.036
body morphogenesis GO:0010171 2 0.036
positive regulation of protein metabolic process GO:0051247 128 0.036
regulation of programmed cell death GO:0043067 152 0.035
reproductive structure development GO:0048608 74 0.035
Worm
positive regulation of cellular protein metabolic process GO:0032270 118 0.035
germarium derived oocyte differentiation GO:0030706 29 0.035
negative regulation of cell death GO:0060548 81 0.035
positive regulation of cell communication GO:0010647 250 0.034
Fly
regulation of cellular protein catabolic process GO:1903362 44 0.034
regulation of molecular function GO:0065009 217 0.034
Mouse
posttranscriptional regulation of gene expression GO:0010608 145 0.034
chromatin modification GO:0016568 147 0.034
production of small rna involved in gene silencing by rna GO:0070918 15 0.033
positive regulation of organelle organization GO:0010638 65 0.033
proteasomal protein catabolic process GO:0010498 59 0.032
metaphase anaphase transition of cell cycle GO:0044784 28 0.032
establishment of mitotic spindle localization GO:0040001 17 0.032
regulation of mitotic cell cycle GO:0007346 190 0.032
negative regulation of biosynthetic process GO:0009890 277 0.032
cell cycle checkpoint GO:0000075 95 0.032
dna replication GO:0006260 48 0.031
establishment of spindle localization GO:0051293 22 0.031
positive regulation of chromosome segregation GO:0051984 10 0.031
spindle elongation GO:0051231 83 0.029
organic cyclic compound catabolic process GO:1901361 168 0.029
immune system development GO:0002520 57 0.028
negative regulation of rna metabolic process GO:0051253 251 0.028
mitotic cytokinesis GO:0000281 50 0.028
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.028
spermatid differentiation GO:0048515 114 0.028
chromosome localization GO:0050000 20 0.027
epithelial cell development GO:0002064 274 0.026
spermatid development GO:0007286 98 0.026
attachment of spindle microtubules to kinetochore GO:0008608 5 0.026
negative regulation of cellular component organization GO:0051129 108 0.025
macromolecule catabolic process GO:0009057 161 0.025
single organism catabolic process GO:0044712 228 0.024
negative regulation of organelle organization GO:0010639 56 0.024
regulation of chromatin silencing GO:0031935 36 0.024
cellular nitrogen compound catabolic process GO:0044270 165 0.023
nuclear dna replication GO:0033260 1 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.023
regulation of mitotic spindle elongation GO:0032888 1 0.023
embryonic development via the syncytial blastoderm GO:0001700 148 0.023
regulation of protein catabolic process GO:0042176 55 0.023
positive regulation of cellular catabolic process GO:0031331 95 0.022
meiotic cytokinesis GO:0033206 33 0.022
intracellular signal transduction GO:0035556 300 0.021
Human Mouse Fly
negative regulation of cell proliferation GO:0008285 69 0.021
response to organic cyclic compound GO:0014070 89 0.021
cardiovascular system development GO:0072358 82 0.021
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.020
single organism cellular localization GO:1902580 180 0.020
anatomical structure homeostasis GO:0060249 97 0.020
negative regulation of microtubule depolymerization GO:0007026 21 0.020
regulation of cell proliferation GO:0042127 163 0.019
mitotic cell cycle phase transition GO:0044772 138 0.019
purine ribonucleoside metabolic process GO:0046128 127 0.019
dna methylation or demethylation GO:0044728 4 0.019
negative regulation of gene expression epigenetic GO:0045814 77 0.019
heterocycle catabolic process GO:0046700 166 0.019
regulation of cellular catabolic process GO:0031329 157 0.018
negative regulation of nucleic acid templated transcription GO:1903507 240 0.018
reciprocal dna recombination GO:0035825 19 0.018
protein dna complex assembly GO:0065004 63 0.018
negative regulation of neurogenesis GO:0050768 53 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
ribose phosphate metabolic process GO:0019693 145 0.017
gland development GO:0048732 191 0.017
cellular component disassembly GO:0022411 46 0.017
Human
anterior posterior pattern specification GO:0009952 136 0.017
organonitrogen compound catabolic process GO:1901565 128 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
meiotic sister chromatid cohesion GO:0051177 6 0.017
macromolecule methylation GO:0043414 45 0.017
sex differentiation GO:0007548 81 0.017
Worm
positive regulation of proteolysis GO:0045862 52 0.017
negative regulation of transcription dna templated GO:0045892 237 0.017
single fertilization GO:0007338 24 0.016
cell cycle dna replication GO:0044786 23 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
negative regulation of neuroblast proliferation GO:0007406 27 0.016
cytokinetic cell separation GO:0000920 1 0.016
g2 dna damage checkpoint GO:0031572 69 0.016
developmental growth GO:0048589 280 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.016
cellular response to light stimulus GO:0071482 37 0.016
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.016
regulation of apoptotic process GO:0042981 130 0.016
sister chromatid cohesion GO:0007062 18 0.015
regulation of sister chromatid segregation GO:0033045 28 0.015
positive regulation of response to stimulus GO:0048584 323 0.015
Fly
purine containing compound catabolic process GO:0072523 112 0.015
negative regulation of apoptotic process GO:0043066 63 0.015
negative regulation of cell cycle process GO:0010948 109 0.015
cell cycle arrest GO:0007050 4 0.015
growth GO:0040007 359 0.014
regulation of microtubule depolymerization GO:0031114 24 0.014
organonitrogen compound metabolic process GO:1901564 318 0.014
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.014
muscle system process GO:0003012 21 0.014
spindle assembly involved in female meiosis i GO:0007057 5 0.014
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.014
positive regulation of cellular protein catabolic process GO:1903364 24 0.014
negative regulation of cellular metabolic process GO:0031324 382 0.014
Mouse
regulation of cell cycle phase transition GO:1901987 130 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
protein catabolic process GO:0030163 101 0.014
microtubule based movement GO:0007018 51 0.014
regionalization GO:0003002 416 0.013
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.013
positive regulation of protein modification process GO:0031401 58 0.013
dendrite morphogenesis GO:0048813 199 0.013
methylation GO:0032259 47 0.013
germarium derived oocyte fate determination GO:0007294 26 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
regulation of cytokinesis GO:0032465 3 0.013
protein depolymerization GO:0051261 31 0.013
proteolysis GO:0006508 192 0.013
response to organic substance GO:0010033 284 0.013
Human Worm
protein alkylation GO:0008213 43 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
negative regulation of microtubule polymerization or depolymerization GO:0031111 21 0.013
female germ line cyst formation GO:0048135 42 0.013
oxoacid metabolic process GO:0043436 103 0.012
distributive segregation GO:0032837 6 0.012
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.012
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.012
negative regulation of nucleotide metabolic process GO:0045980 4 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.012
protein localization GO:0008104 284 0.012
regulation of spindle elongation GO:0032887 1 0.012
negative regulation of signal transduction by p53 class mediator GO:1901797 1 0.012
negative regulation of transcription factor import into nucleus GO:0042992 4 0.012
response to light stimulus GO:0009416 124 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
localization of cell GO:0051674 257 0.012
organic acid metabolic process GO:0006082 103 0.012
larval development GO:0002164 104 0.012
kinetochore organization GO:0051383 9 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
protein localization to chromatin GO:0071168 3 0.011
negative regulation of protein processing GO:0010955 31 0.011
cellular homeostasis GO:0019725 80 0.011
centrosome duplication GO:0051298 121 0.011
microtubule polymerization GO:0046785 15 0.011
regulation of cell shape GO:0008360 113 0.011
regulation of neuron projection development GO:0010975 69 0.011
establishment of localization in cell GO:0051649 402 0.011
positive regulation of protein catabolic process GO:0045732 34 0.011
response to radiation GO:0009314 155 0.011
regulation of cell morphogenesis GO:0022604 163 0.011
regulation of cell death GO:0010941 173 0.011
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
Fly
ubiquitin dependent protein catabolic process GO:0006511 78 0.010
nucleotide metabolic process GO:0009117 161 0.010
regulation of neurogenesis GO:0050767 158 0.010
regulation of erk1 and erk2 cascade GO:0070372 39 0.010
Mouse Fly
actin filament based process GO:0030029 220 0.010
positive regulation of macromolecule metabolic process GO:0010604 405 0.010
regulation of hemocyte proliferation GO:0035206 37 0.010
ribonucleoside catabolic process GO:0042454 112 0.010
protein modification by small protein conjugation or removal GO:0070647 106 0.010

ball disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
disease of cellular proliferation DOID:14566 0 0.024
cancer DOID:162 0 0.017
organ system cancer DOID:0050686 0 0.015