Drosophila melanogaster

0 known processes

Cchl (Dmel_CG6022)

Cytochrome c heme lyase

(Aliases: Dmel\CG6022,cchl,CG6022)

Cchl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cell communication GO:0010648 223 0.196
mitochondrion organization GO:0007005 65 0.180
negative regulation of cellular biosynthetic process GO:0031327 277 0.166
cell proliferation GO:0008283 299 0.154
glutathione metabolic process GO:0006749 37 0.115
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.115
cellular amino acid metabolic process GO:0006520 61 0.112
programmed cell death GO:0012501 257 0.100
response to nutrient levels GO:0031667 114 0.098
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.092
transcription from rna polymerase ii promoter GO:0006366 368 0.085
negative regulation of gene expression GO:0010629 387 0.083
endocytosis GO:0006897 310 0.083
negative regulation of cellular metabolic process GO:0031324 382 0.081
embryo development ending in birth or egg hatching GO:0009792 152 0.080
regulation of cell death GO:0010941 173 0.080
establishment of localization in cell GO:0051649 402 0.078
organonitrogen compound metabolic process GO:1901564 318 0.076
negative regulation of biosynthetic process GO:0009890 277 0.072
regulation of cellular protein metabolic process GO:0032268 243 0.066
apoptotic process GO:0006915 159 0.062
regulation of localization GO:0032879 275 0.061
oocyte differentiation GO:0009994 145 0.058
negative regulation of response to stimulus GO:0048585 258 0.058
cell death GO:0008219 279 0.054
immune system process GO:0002376 347 0.052
negative regulation of signal transduction GO:0009968 206 0.052
negative regulation of signaling GO:0023057 219 0.051
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.051
endomembrane system organization GO:0010256 119 0.051
golgi organization GO:0007030 66 0.050
cellular catabolic process GO:0044248 372 0.050
death GO:0016265 284 0.049
regulation of phosphorus metabolic process GO:0051174 210 0.048
small molecule metabolic process GO:0044281 305 0.048
regulation of autophagy GO:0010506 62 0.048
developmental maturation GO:0021700 172 0.048
negative regulation of nucleic acid templated transcription GO:1903507 240 0.047
regionalization GO:0003002 416 0.047
male gamete generation GO:0048232 201 0.046
peptide metabolic process GO:0006518 80 0.046
carboxylic acid metabolic process GO:0019752 92 0.046
organic substance transport GO:0071702 257 0.044
regulation of phosphate metabolic process GO:0019220 210 0.044
negative regulation of rna metabolic process GO:0051253 251 0.043
oxoacid metabolic process GO:0043436 103 0.043
intracellular signal transduction GO:0035556 300 0.043
organonitrogen compound biosynthetic process GO:1901566 117 0.042
cellular amide metabolic process GO:0043603 80 0.042
vesicle mediated transport GO:0016192 381 0.041
protein localization GO:0008104 284 0.040
regulation of cell proliferation GO:0042127 163 0.039
response to organic substance GO:0010033 284 0.038
establishment of protein localization GO:0045184 163 0.038
activation of cysteine type endopeptidase activity GO:0097202 17 0.037
cell maturation GO:0048469 144 0.037
regulation of cellular amine metabolic process GO:0033238 3 0.037
regulation of protein metabolic process GO:0051246 256 0.037
negative regulation of transcription dna templated GO:0045892 237 0.036
negative regulation of epithelial cell proliferation GO:0050680 4 0.036
cellular macromolecule localization GO:0070727 220 0.036
catabolic process GO:0009056 409 0.034
organic acid metabolic process GO:0006082 103 0.034
regulation of intracellular signal transduction GO:1902531 236 0.034
cellular amine metabolic process GO:0044106 12 0.033
spermatid development GO:0007286 98 0.033
oxidation reduction process GO:0055114 123 0.032
membrane organization GO:0061024 112 0.032
protein transport GO:0015031 155 0.032
response to inorganic substance GO:0010035 44 0.031
phosphorylation GO:0016310 294 0.031
regulation of programmed cell death GO:0043067 152 0.031
response to extracellular stimulus GO:0009991 116 0.031
regulation of molecular function GO:0065009 217 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.031
axis specification GO:0009798 167 0.030
regulation of cell cycle phase transition GO:1901987 130 0.030
regulation of epithelial cell proliferation GO:0050678 4 0.029
regulation of cell cycle GO:0051726 291 0.029
response to abiotic stimulus GO:0009628 341 0.029
cytoplasmic transport GO:0016482 130 0.029
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.028
positive regulation of macromolecule metabolic process GO:0010604 405 0.028
neurological system process GO:0050877 358 0.028
anterior posterior pattern specification GO:0009952 136 0.028
cellular protein modification process GO:0006464 438 0.027
regulation of transport GO:0051049 181 0.027
developmental growth GO:0048589 280 0.027
cellular response to chemical stimulus GO:0070887 199 0.027
chromosome organization GO:0051276 360 0.027
connective tissue development GO:0061448 3 0.027
single organism intracellular transport GO:1902582 207 0.026
protein modification process GO:0036211 438 0.026
negative regulation of protein metabolic process GO:0051248 85 0.026
dna metabolic process GO:0006259 227 0.026
single organism cellular localization GO:1902580 180 0.026
negative regulation of rna biosynthetic process GO:1902679 240 0.026
regulation of proteolysis GO:0030162 87 0.025
spermatogenesis GO:0007283 200 0.025
epithelial cell differentiation GO:0030855 322 0.025
immune response GO:0006955 246 0.025
oocyte axis specification GO:0007309 108 0.025
protein maturation GO:0051604 71 0.024
neuromuscular junction development GO:0007528 149 0.024
oocyte construction GO:0007308 112 0.024
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.024
head development GO:0060322 135 0.024
regulation of cellular catabolic process GO:0031329 157 0.023
protein processing GO:0016485 68 0.023
negative regulation of cellular protein metabolic process GO:0032269 85 0.023
nucleoside triphosphate metabolic process GO:0009141 120 0.023
nucleotide metabolic process GO:0009117 161 0.023
autophagy GO:0006914 108 0.023
single organism membrane organization GO:0044802 93 0.023
protein modification by small protein conjugation GO:0032446 79 0.023
compound eye morphogenesis GO:0001745 249 0.023
amine metabolic process GO:0009308 12 0.022
negative regulation of cell death GO:0060548 81 0.022
negative regulation of cell proliferation GO:0008285 69 0.022
positive regulation of cellular biosynthetic process GO:0031328 316 0.022
single organism biosynthetic process GO:0044711 206 0.022
cellular protein localization GO:0034613 160 0.022
developmental programmed cell death GO:0010623 138 0.021
protein modification by small protein conjugation or removal GO:0070647 106 0.021
negative regulation of neural precursor cell proliferation GO:2000178 27 0.021
mitotic cell cycle checkpoint GO:0007093 88 0.021
blastoderm segmentation GO:0007350 159 0.021
negative regulation of phosphorus metabolic process GO:0010563 45 0.021
nucleobase containing small molecule metabolic process GO:0055086 174 0.020
posttranscriptional regulation of gene expression GO:0010608 145 0.020
regulation of phosphorylation GO:0042325 147 0.019
zymogen activation GO:0031638 20 0.019
regulation of developmental growth GO:0048638 174 0.019
organic substance catabolic process GO:1901575 308 0.019
sensory organ morphogenesis GO:0090596 260 0.019
wing disc morphogenesis GO:0007472 344 0.019
cellular lipid metabolic process GO:0044255 83 0.019
positive regulation of molecular function GO:0044093 136 0.019
cellular response to dna damage stimulus GO:0006974 223 0.018
protein ubiquitination GO:0016567 70 0.018
mitotic nuclear division GO:0007067 213 0.018
regulation of cell differentiation GO:0045595 302 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
intracellular protein transmembrane transport GO:0065002 4 0.018
response to radiation GO:0009314 155 0.018
positive regulation of cell communication GO:0010647 250 0.018
pole plasm assembly GO:0007315 61 0.018
ribonucleoside metabolic process GO:0009119 127 0.017
purine ribonucleoside metabolic process GO:0046128 127 0.017
hematopoietic progenitor cell differentiation GO:0002244 1 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.017
negative regulation of developmental process GO:0051093 201 0.017
positive regulation of programmed cell death GO:0043068 62 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
larval development GO:0002164 104 0.017
embryonic pattern specification GO:0009880 174 0.017
cellular response to organic substance GO:0071310 132 0.017
tripartite regional subdivision GO:0007351 103 0.016
localization of cell GO:0051674 257 0.016
intracellular protein transport GO:0006886 104 0.016
small molecule biosynthetic process GO:0044283 37 0.016
protein import GO:0017038 55 0.016
cell migration GO:0016477 238 0.016
regulation of nervous system development GO:0051960 248 0.016
regulation of catalytic activity GO:0050790 185 0.016
positive regulation of peptidase activity GO:0010952 29 0.015
negative regulation of cellular component organization GO:0051129 108 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.015
phagocytosis GO:0006909 215 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
organelle fission GO:0048285 340 0.015
regulation of multicellular organismal development GO:2000026 414 0.015
secretion GO:0046903 109 0.015
posttranscriptional gene silencing GO:0016441 46 0.015
compound eye development GO:0048749 307 0.015
forebrain development GO:0030900 2 0.015
positive regulation of cell death GO:0010942 69 0.015
instar larval development GO:0002168 55 0.015
positive regulation of proteolysis GO:0045862 52 0.015
oocyte development GO:0048599 124 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.015
germarium derived egg chamber formation GO:0007293 101 0.015
regulation of notch signaling pathway GO:0008593 100 0.015
negative regulation of transferase activity GO:0051348 18 0.014
cell motility GO:0048870 251 0.014
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
appendage development GO:0048736 401 0.014
eye development GO:0001654 323 0.014
positive regulation of hydrolase activity GO:0051345 78 0.014
regulation of immune system process GO:0002682 176 0.014
negative regulation of intracellular signal transduction GO:1902532 57 0.014
sister chromatid segregation GO:0000819 92 0.014
posttranscriptional gene silencing by rna GO:0035194 45 0.014
protein transmembrane transport GO:0071806 4 0.014
purine containing compound metabolic process GO:0072521 155 0.014
regulation of organelle organization GO:0033043 196 0.014
oocyte anterior posterior axis specification GO:0007314 72 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
translational elongation GO:0006414 4 0.013
regulation of apoptotic process GO:0042981 130 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
regulation of translation GO:0006417 56 0.013
g2 dna damage checkpoint GO:0031572 69 0.013
homeostatic process GO:0042592 199 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
regulation of protein modification process GO:0031399 112 0.013
regulation of cysteine type endopeptidase activity GO:2000116 27 0.013
response to other organism GO:0051707 293 0.013
detection of stimulus GO:0051606 156 0.013
wing disc dorsal ventral pattern formation GO:0048190 47 0.013
negative regulation of phosphorylation GO:0042326 35 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
regulation of neural precursor cell proliferation GO:2000177 35 0.013
innate immune response GO:0045087 144 0.013
mesenchymal cell differentiation GO:0048762 1 0.013
organophosphate metabolic process GO:0019637 195 0.013
cellular ion homeostasis GO:0006873 39 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.013
negative regulation of cell cycle phase transition GO:1901988 103 0.013
sulfur compound metabolic process GO:0006790 59 0.013
phosphatidylinositol mediated signaling GO:0048015 4 0.012
dendrite morphogenesis GO:0048813 199 0.012
proteolysis GO:0006508 192 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
glycerolipid metabolic process GO:0046486 34 0.012
embryonic axis specification GO:0000578 107 0.012
secretion by cell GO:0032940 101 0.012
regulation of chromosome organization GO:0033044 64 0.012
cellular protein catabolic process GO:0044257 83 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
pole plasm oskar mrna localization GO:0045451 46 0.012
regulation of response to stress GO:0080134 200 0.012
imaginal disc derived appendage development GO:0048737 399 0.012
chromosome segregation GO:0007059 157 0.012
tricarboxylic acid metabolic process GO:0072350 1 0.012
cellular response to external stimulus GO:0071496 66 0.012
protein secretion GO:0009306 45 0.012
negative regulation of mitotic cell cycle GO:0045930 109 0.012
larval behavior GO:0030537 42 0.011
positive regulation of cell motility GO:2000147 3 0.011
regulation of erbb signaling pathway GO:1901184 42 0.011
mitotic sister chromatid segregation GO:0000070 87 0.011
protein phosphorylation GO:0006468 169 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
body morphogenesis GO:0010171 2 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
negative regulation of catalytic activity GO:0043086 42 0.011
sex differentiation GO:0007548 81 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
organelle membrane fusion GO:0090174 16 0.011
protein catabolic process GO:0030163 101 0.011
synaptic growth at neuromuscular junction GO:0051124 119 0.011
cellularization GO:0007349 90 0.011
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.011
positive regulation of signaling GO:0023056 243 0.011
response to biotic stimulus GO:0009607 294 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
appendage morphogenesis GO:0035107 397 0.011
regulation of catabolic process GO:0009894 170 0.011
protein complex assembly GO:0006461 200 0.011
cellular metal ion homeostasis GO:0006875 31 0.011
negative regulation of nervous system development GO:0051961 92 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.011
response to endogenous stimulus GO:0009719 119 0.011
regulation of transferase activity GO:0051338 58 0.011
stem cell differentiation GO:0048863 117 0.011
protein localization to organelle GO:0033365 82 0.011
cell cycle checkpoint GO:0000075 95 0.011
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.011
defense response GO:0006952 300 0.010
single organism membrane fusion GO:0044801 42 0.010
regulation of defense response GO:0031347 102 0.010
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.010
organophosphate biosynthetic process GO:0090407 46 0.010
positive regulation of apoptotic process GO:0043065 47 0.010
cellular modified amino acid metabolic process GO:0006575 45 0.010
regulation of innate immune response GO:0045088 71 0.010
regulation of gene expression epigenetic GO:0040029 128 0.010
nephron epithelium development GO:0072009 3 0.010
nephron development GO:0072006 3 0.010
regulation of endopeptidase activity GO:0052548 36 0.010

Cchl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.026
disease of metabolism DOID:0014667 0 0.025
cancer DOID:162 0 0.023
disease of cellular proliferation DOID:14566 0 0.023
organ system cancer DOID:0050686 0 0.023
inherited metabolic disorder DOID:655 0 0.016
central nervous system disease DOID:331 0 0.013
sensory system disease DOID:0050155 0 0.012