Drosophila melanogaster

96 known processes

shd (Dmel_CG13478)

shade

(Aliases: Dmel\CG13478,314a1,CG13478,Cyp314a1,CYP314A1)

shd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ovarian follicle cell migration GO:0007297 121 0.856
morphogenesis of embryonic epithelium GO:0016331 94 0.812
tissue migration GO:0090130 155 0.760
ovarian follicle cell development GO:0030707 248 0.754
chitin based embryonic cuticle biosynthetic process GO:0008362 16 0.677
Fly
columnar cuboidal epithelial cell development GO:0002066 249 0.651
border follicle cell migration GO:0007298 113 0.644
embryonic morphogenesis GO:0048598 206 0.634
head involution GO:0008258 35 0.634
cell migration GO:0016477 238 0.575
ameboidal type cell migration GO:0001667 151 0.515
digestive tract development GO:0048565 149 0.371
epithelium migration GO:0090132 148 0.357
dorsal closure GO:0007391 79 0.348
tube development GO:0035295 244 0.329
tissue morphogenesis GO:0048729 297 0.310
response to starvation GO:0042594 97 0.271
embryo development ending in birth or egg hatching GO:0009792 152 0.271
central nervous system development GO:0007417 201 0.271
embryonic development via the syncytial blastoderm GO:0001700 148 0.261
fat soluble vitamin biosynthetic process GO:0042362 1 0.255
ecdysone biosynthetic process GO:0006697 9 0.209
Fly
ketone biosynthetic process GO:0042181 16 0.193
cuticle development GO:0042335 86 0.187
Fly
localization of cell GO:0051674 257 0.184
cellular response to external stimulus GO:0071496 66 0.183
response to extracellular stimulus GO:0009991 116 0.179
morphogenesis of an epithelium GO:0002009 276 0.179
hormone biosynthetic process GO:0042446 20 0.174
epithelial cell development GO:0002064 274 0.170
cell motility GO:0048870 251 0.170
epithelial cell migration GO:0010631 148 0.168
small molecule metabolic process GO:0044281 305 0.157
midgut development GO:0007494 23 0.157
negative regulation of cellular metabolic process GO:0031324 382 0.152
ecdysteroid metabolic process GO:0045455 19 0.149
regulation of growth GO:0040008 233 0.140
cellular catabolic process GO:0044248 372 0.136
steroid catabolic process GO:0006706 1 0.136
negative regulation of cellular biosynthetic process GO:0031327 277 0.126
cellular response to extracellular stimulus GO:0031668 64 0.122
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.120
small molecule biosynthetic process GO:0044283 37 0.118
single organism biosynthetic process GO:0044711 206 0.113
tube morphogenesis GO:0035239 191 0.111
digestive system development GO:0055123 149 0.110
negative regulation of biosynthetic process GO:0009890 277 0.108
developmental growth GO:0048589 280 0.108
cellular response to nutrient levels GO:0031669 62 0.096
response to endogenous stimulus GO:0009719 119 0.095
organic hydroxy compound biosynthetic process GO:1901617 21 0.094
Fly
response to nutrient levels GO:0031667 114 0.092
epithelial cell differentiation GO:0030855 322 0.089
cellular response to starvation GO:0009267 61 0.086
organic hydroxy compound metabolic process GO:1901615 83 0.085
Fly
carbohydrate derivative metabolic process GO:1901135 217 0.080
hormone metabolic process GO:0042445 33 0.079
developmental programmed cell death GO:0010623 138 0.077
cellular hormone metabolic process GO:0034754 23 0.077
regulation of multicellular organismal development GO:2000026 414 0.076
lipid metabolic process GO:0006629 121 0.073
cellular ketone metabolic process GO:0042180 24 0.073
regulation of response to stress GO:0080134 200 0.071
alcohol metabolic process GO:0006066 25 0.069
Fly
regulation of response to nutrient levels GO:0032107 18 0.067
regulation of response to extracellular stimulus GO:0032104 18 0.065
sterol biosynthetic process GO:0016126 9 0.062
Fly
response to alcohol GO:0097305 95 0.061
negative regulation of rna biosynthetic process GO:1902679 240 0.061
digestive tract morphogenesis GO:0048546 127 0.059
ecdysteroid biosynthetic process GO:0045456 15 0.058
regulation of protein metabolic process GO:0051246 256 0.055
regulation of anatomical structure morphogenesis GO:0022603 242 0.054
organic cyclic compound catabolic process GO:1901361 168 0.054
regulation of cell differentiation GO:0045595 302 0.053
renal system process GO:0003014 12 0.053
chitin based cuticle development GO:0040003 49 0.053
Fly
protein modification process GO:0036211 438 0.052
actin cytoskeleton organization GO:0030036 206 0.051
negative regulation of cell communication GO:0010648 223 0.049
positive regulation of response to stimulus GO:0048584 323 0.048
negative regulation of rna metabolic process GO:0051253 251 0.047
lipid biosynthetic process GO:0008610 46 0.047
response to bacterium GO:0009617 198 0.046
positive regulation of multicellular organismal process GO:0051240 143 0.046
transcription from rna polymerase ii promoter GO:0006366 368 0.045
defense response GO:0006952 300 0.045
cellular protein modification process GO:0006464 438 0.044
respiratory system development GO:0060541 213 0.044
cellular response to peptide GO:1901653 28 0.044
positive regulation of signaling GO:0023056 243 0.043
vesicle mediated transport GO:0016192 381 0.043
cellular response to organic substance GO:0071310 132 0.043
amino sugar metabolic process GO:0006040 10 0.043
body morphogenesis GO:0010171 2 0.042
maintenance of location GO:0051235 73 0.042
torso signaling pathway GO:0008293 21 0.041
response to nitrogen compound GO:1901698 90 0.041
positive regulation of signal transduction GO:0009967 223 0.040
embryonic pattern specification GO:0009880 174 0.040
single organism catabolic process GO:0044712 228 0.040
regulation of molecular function GO:0065009 217 0.040
endocytosis GO:0006897 310 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.039
vitamin biosynthetic process GO:0009110 1 0.039
regulation of cellular catabolic process GO:0031329 157 0.038
open tracheal system development GO:0007424 204 0.038
steroid metabolic process GO:0008202 20 0.037
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.037
fat soluble vitamin metabolic process GO:0006775 1 0.037
steroid biosynthetic process GO:0006694 16 0.037
regulation of cellular response to stress GO:0080135 89 0.037
response to lipopolysaccharide GO:0032496 4 0.035
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.035
positive regulation of developmental growth GO:0048639 62 0.035
lipid catabolic process GO:0016042 21 0.035
alcohol biosynthetic process GO:0046165 14 0.035
Fly
polyol biosynthetic process GO:0046173 3 0.034
sterol metabolic process GO:0016125 12 0.034
Fly
positive regulation of cell communication GO:0010647 250 0.034
cell projection assembly GO:0030031 94 0.033
immune response activating signal transduction GO:0002757 2 0.033
regulation of catabolic process GO:0009894 170 0.033
organophosphate metabolic process GO:0019637 195 0.033
positive regulation of cell differentiation GO:0045597 64 0.032
growth GO:0040007 359 0.032
organic substance catabolic process GO:1901575 308 0.031
establishment of localization in cell GO:0051649 402 0.031
immune response GO:0006955 246 0.031
innate immune response GO:0045087 144 0.030
regulation of cell death GO:0010941 173 0.029
positive regulation of epithelial cell differentiation GO:0030858 1 0.029
response to organic substance GO:0010033 284 0.029
Fly
regulation of cellular protein metabolic process GO:0032268 243 0.029
cell growth GO:0016049 108 0.029
regulation of nervous system development GO:0051960 248 0.029
response to hormone GO:0009725 45 0.029
purine containing compound metabolic process GO:0072521 155 0.029
response to oxygen containing compound GO:1901700 200 0.029
carbohydrate derivative biosynthetic process GO:1901137 85 0.028
positive regulation of cellular component organization GO:0051130 156 0.028
imaginal disc derived appendage morphogenesis GO:0035114 395 0.028
regulation of organelle organization GO:0033043 196 0.028
negative regulation of signaling GO:0023057 219 0.028
response to organic cyclic compound GO:0014070 89 0.028
Fly
regulation of hormone levels GO:0010817 40 0.027
negative regulation of transcription dna templated GO:0045892 237 0.027
organelle fission GO:0048285 340 0.027
renal tubule development GO:0061326 64 0.027
response to biotic stimulus GO:0009607 294 0.027
ribonucleotide catabolic process GO:0009261 109 0.027
purine nucleotide metabolic process GO:0006163 146 0.027
cellular response to mechanical stimulus GO:0071260 2 0.026
regulation of steroid metabolic process GO:0019218 2 0.026
compound eye morphogenesis GO:0001745 249 0.026
cellular response to endogenous stimulus GO:0071495 80 0.026
regulation of phosphorus metabolic process GO:0051174 210 0.026
cell proliferation GO:0008283 299 0.026
secretion GO:0046903 109 0.026
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.026
ecdysone metabolic process GO:0008205 11 0.026
Fly
regulation of intracellular signal transduction GO:1902531 236 0.026
segmentation GO:0035282 207 0.025
anatomical structure homeostasis GO:0060249 97 0.025
regulation of cell proliferation GO:0042127 163 0.024
regulation of localization GO:0032879 275 0.024
protein complex biogenesis GO:0070271 201 0.024
immune system process GO:0002376 347 0.024
response to external biotic stimulus GO:0043207 293 0.024
taxis GO:0042330 304 0.024
Fly
catabolic process GO:0009056 409 0.024
defense response to other organism GO:0098542 225 0.024
death GO:0016265 284 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.023
organonitrogen compound biosynthetic process GO:1901566 117 0.023
cardioblast cell fate commitment GO:0042684 14 0.023
cellular response to metal ion GO:0071248 6 0.023
cellular response to oxygen containing compound GO:1901701 79 0.023
epithelial cell migration open tracheal system GO:0007427 32 0.023
regionalization GO:0003002 416 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.023
axon guidance GO:0007411 233 0.023
Fly
appendage development GO:0048736 401 0.023
regulation of response to external stimulus GO:0032101 115 0.023
reproductive system development GO:0061458 74 0.023
malpighian tubule morphogenesis GO:0007443 44 0.022
mapk cascade GO:0000165 107 0.022
biological adhesion GO:0022610 138 0.022
axon development GO:0061564 297 0.022
Fly
axonogenesis GO:0007409 290 0.022
Fly
response to heat GO:0009408 63 0.022
nuclear division GO:0000280 332 0.022
membrane organization GO:0061024 112 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.021
positive regulation of gtpase activity GO:0043547 43 0.021
glucosamine containing compound metabolic process GO:1901071 9 0.021
cell division GO:0051301 248 0.021
purine nucleotide catabolic process GO:0006195 109 0.020
phagocytosis GO:0006909 215 0.020
response to drug GO:0042493 17 0.020
skin development GO:0043588 65 0.020
response to organonitrogen compound GO:0010243 75 0.020
proteolysis GO:0006508 192 0.020
vitamin metabolic process GO:0006766 2 0.020
cellular response to chemical stimulus GO:0070887 199 0.020
positive regulation of nucleotide metabolic process GO:0045981 55 0.019
heterocycle catabolic process GO:0046700 166 0.019
phosphorylation GO:0016310 294 0.019
cellular response to nitrogen compound GO:1901699 51 0.019
actin filament based process GO:0030029 220 0.019
regulation of epithelial cell differentiation GO:0030856 4 0.019
positive regulation of catabolic process GO:0009896 105 0.019
regulation of cell adhesion GO:0030155 27 0.019
cardiac cell fate commitment GO:0060911 17 0.019
signal transduction by phosphorylation GO:0023014 107 0.018
purine containing compound catabolic process GO:0072523 112 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
regulation of protein complex assembly GO:0043254 42 0.018
response to peptide GO:1901652 29 0.018
circulatory system process GO:0003013 37 0.018
chorion containing eggshell formation GO:0007304 105 0.018
negative regulation of nucleic acid templated transcription GO:1903507 240 0.018
cellular response to hormone stimulus GO:0032870 44 0.018
positive regulation of cell motility GO:2000147 3 0.018
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
purine ribonucleotide catabolic process GO:0009154 109 0.018
axis specification GO:0009798 167 0.018
positive regulation of developmental process GO:0051094 143 0.018
apoptotic process GO:0006915 159 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
germ band shortening GO:0007390 19 0.018
intracellular signal transduction GO:0035556 300 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.017
protein polymerization GO:0051258 42 0.017
multicellular organism growth GO:0035264 46 0.017
kidney development GO:0001822 3 0.017
protein localization GO:0008104 284 0.017
multicellular organismal aging GO:0010259 140 0.017
nucleobase containing compound catabolic process GO:0034655 165 0.017
nephron tubule morphogenesis GO:0072078 3 0.017
motor neuron axon guidance GO:0008045 58 0.017
Fly
defense response to bacterium GO:0042742 178 0.017
cytoplasmic transport GO:0016482 130 0.017
regulation of cell morphogenesis GO:0022604 163 0.017
organic substance transport GO:0071702 257 0.017
homeostatic process GO:0042592 199 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
wound healing GO:0042060 75 0.016
regulation of small gtpase mediated signal transduction GO:0051056 93 0.016
protein complex assembly GO:0006461 200 0.016
visual learning GO:0008542 4 0.016
lipid storage GO:0019915 38 0.016
ribonucleoside triphosphate catabolic process GO:0009203 108 0.016
regulation of embryonic development GO:0045995 68 0.016
response to peptide hormone GO:0043434 29 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
response to insulin GO:0032868 29 0.016
nucleoside phosphate catabolic process GO:1901292 110 0.016
negative regulation of growth GO:0045926 84 0.016
stem cell differentiation GO:0048863 117 0.016
positive regulation of cell migration GO:0030335 2 0.016
cell adhesion GO:0007155 136 0.016
kidney epithelium development GO:0072073 3 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
regulation of developmental growth GO:0048638 174 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
regulation of cell development GO:0060284 215 0.016
macromolecular complex assembly GO:0065003 256 0.015
blastoderm segmentation GO:0007350 159 0.015
nucleotide metabolic process GO:0009117 161 0.015
positive regulation of molecular function GO:0044093 136 0.015
learning GO:0007612 75 0.015
regulation of protein polymerization GO:0032271 28 0.015
determination of adult lifespan GO:0008340 137 0.015
response to abiotic stimulus GO:0009628 341 0.015
cardiocyte differentiation GO:0035051 29 0.015
regulation of synapse assembly GO:0051963 94 0.015
organophosphate catabolic process GO:0046434 112 0.015
positive regulation of nucleoside metabolic process GO:0045979 47 0.015
regulation of hydrolase activity GO:0051336 97 0.015
ovarian nurse cell to oocyte transport GO:0007300 27 0.015
positive regulation of cytoskeleton organization GO:0051495 21 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
negative regulation of gene expression GO:0010629 387 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.015
positive regulation of growth GO:0045927 75 0.015
regulation of cellular localization GO:0060341 136 0.015
actin filament organization GO:0007015 126 0.015
regulation of tube diameter GO:0035296 14 0.015
regulation of microtubule based process GO:0032886 49 0.014
negative regulation of molecular function GO:0044092 51 0.014
regulation of epidermal cell differentiation GO:0045604 3 0.014
autophagy GO:0006914 108 0.014
regulation of immune system process GO:0002682 176 0.014
aggressive behavior GO:0002118 63 0.014
chromosome segregation GO:0007059 157 0.014
anterior posterior axis specification embryo GO:0008595 103 0.014
dendrite development GO:0016358 204 0.014
establishment of organelle localization GO:0051656 122 0.014
negative regulation of catalytic activity GO:0043086 42 0.014
glycosyl compound catabolic process GO:1901658 112 0.014
gland morphogenesis GO:0022612 145 0.014
microtubule polymerization or depolymerization GO:0031109 39 0.014
purine ribonucleoside metabolic process GO:0046128 127 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
regulation of cell shape GO:0008360 113 0.014
glial cell differentiation GO:0010001 35 0.013
apoptotic process involved in development GO:1902742 20 0.013
forebrain development GO:0030900 2 0.013
regulation of transport GO:0051049 181 0.013
regulation of mapk cascade GO:0043408 92 0.013
cardioblast cell fate determination GO:0007510 3 0.013
organonitrogen compound metabolic process GO:1901564 318 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
positive regulation of cellular component biogenesis GO:0044089 80 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
endomembrane system organization GO:0010256 119 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
ras protein signal transduction GO:0007265 88 0.013
cell fate specification GO:0001708 71 0.013
leg disc development GO:0035218 92 0.013
regulation of cell projection organization GO:0031344 92 0.013
epidermis development GO:0008544 65 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
genital disc development GO:0035215 44 0.012
programmed cell death GO:0012501 257 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
cellular response to peptide hormone stimulus GO:0071375 28 0.012
histolysis GO:0007559 102 0.012
neuron projection guidance GO:0097485 241 0.012
Fly
negative regulation of cell death GO:0060548 81 0.012
cell maturation GO:0048469 144 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.012
negative regulation of wnt signaling pathway GO:0030178 28 0.012
regulation of phosphorylation GO:0042325 147 0.012
epiboly GO:0090504 2 0.012
autophagic cell death GO:0048102 83 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
telencephalon development GO:0021537 2 0.012
regulation of lamellipodium assembly GO:0010591 15 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
negative regulation of signal transduction GO:0009968 206 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.012
regulation of anatomical structure size GO:0090066 163 0.012
negative regulation of cellular protein metabolic process GO:0032269 85 0.012
regulation of apoptotic process GO:0042981 130 0.011
negative regulation of cell proliferation GO:0008285 69 0.011
somatic muscle development GO:0007525 66 0.011
actin polymerization or depolymerization GO:0008154 31 0.011
wing disc morphogenesis GO:0007472 344 0.011
response to organophosphorus GO:0046683 2 0.011
compound eye development GO:0048749 307 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
regulation of notch signaling pathway GO:0008593 100 0.011
eggshell formation GO:0030703 105 0.011
intracellular transport GO:0046907 228 0.011
oxoacid metabolic process GO:0043436 103 0.011
trachea morphogenesis GO:0060439 22 0.011
trachea development GO:0060438 29 0.011
rho protein signal transduction GO:0007266 14 0.011
spinal cord development GO:0021510 1 0.011
protein phosphorylation GO:0006468 169 0.011
positive regulation of nucleotide catabolic process GO:0030813 46 0.011
cellular response to organic cyclic compound GO:0071407 32 0.011
positive regulation of neurogenesis GO:0050769 41 0.011
cytoskeleton dependent cytokinesis GO:0061640 81 0.011
nephron development GO:0072006 3 0.011
dna metabolic process GO:0006259 227 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
lipid localization GO:0010876 54 0.011
nucleoside catabolic process GO:0009164 112 0.011
positive regulation of transport GO:0051050 92 0.011
chemotaxis GO:0006935 249 0.011
Fly
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
meiotic nuclear division GO:0007126 151 0.011
camera type eye morphogenesis GO:0048593 2 0.010
establishment or maintenance of cell polarity GO:0007163 167 0.010
single organism carbohydrate metabolic process GO:0044723 72 0.010
mesodermal cell fate specification GO:0007501 2 0.010
organic hydroxy compound catabolic process GO:1901616 4 0.010
protein processing GO:0016485 68 0.010
mesoderm development GO:0007498 78 0.010
purine nucleoside catabolic process GO:0006152 112 0.010
cellular response to carbohydrate stimulus GO:0071322 4 0.010
connective tissue development GO:0061448 3 0.010
sex differentiation GO:0007548 81 0.010
positive regulation of gene expression GO:0010628 290 0.010
carboxylic acid metabolic process GO:0019752 92 0.010
response to wounding GO:0009611 94 0.010
regulation of nucleotide metabolic process GO:0006140 62 0.010
cell fate determination GO:0001709 91 0.010
single organismal cell cell adhesion GO:0016337 45 0.010
peripheral nervous system development GO:0007422 52 0.010

shd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
musculoskeletal system disease DOID:17 0 0.017
nervous system disease DOID:863 0 0.016
disease of cellular proliferation DOID:14566 0 0.011