Drosophila melanogaster

40 known processes

Orct2 (Dmel_CG13610)

Organic cation transporter 2

(Aliases: Dmel\CG13610,CG13610,EP1072,EP(3)1072,cald,orct2)

Orct2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
growth GO:0040007 359 0.561
regulation of growth GO:0040008 233 0.506
regulation of developmental growth GO:0048638 174 0.307
tube development GO:0035295 244 0.177
regulation of multicellular organismal development GO:2000026 414 0.159
developmental growth GO:0048589 280 0.125
positive regulation of macromolecule metabolic process GO:0010604 405 0.102
cell proliferation GO:0008283 299 0.099
body morphogenesis GO:0010171 2 0.094
eye morphogenesis GO:0048592 260 0.090
negative regulation of growth GO:0045926 84 0.086
extracellular matrix organization GO:0030198 32 0.085
homeostatic process GO:0042592 199 0.077
digestive tract morphogenesis GO:0048546 127 0.072
regulation of cell differentiation GO:0045595 302 0.068
cellular protein modification process GO:0006464 438 0.063
reproductive behavior GO:0019098 122 0.063
imaginal disc derived appendage development GO:0048737 399 0.060
protein modification process GO:0036211 438 0.060
phagocytosis GO:0006909 215 0.060
cellular macromolecule catabolic process GO:0044265 136 0.059
embryonic morphogenesis GO:0048598 206 0.058
catabolic process GO:0009056 409 0.054
appendage development GO:0048736 401 0.053
chaeta development GO:0022416 97 0.053
regionalization GO:0003002 416 0.052
endocytosis GO:0006897 310 0.051
mating GO:0007618 120 0.048
regulation of cellular component size GO:0032535 98 0.047
protein catabolic process GO:0030163 101 0.047
response to abiotic stimulus GO:0009628 341 0.046
compound eye photoreceptor development GO:0042051 78 0.046
positive regulation of protein metabolic process GO:0051247 128 0.045
positive regulation of nucleic acid templated transcription GO:1903508 266 0.044
negative regulation of transcription dna templated GO:0045892 237 0.044
defense response GO:0006952 300 0.043
negative regulation of multicellular organismal process GO:0051241 142 0.043
negative regulation of developmental growth GO:0048640 64 0.042
positive regulation of rna biosynthetic process GO:1902680 266 0.042
modification dependent macromolecule catabolic process GO:0043632 79 0.042
mating behavior GO:0007617 106 0.041
negative regulation of cell differentiation GO:0045596 143 0.041
enzyme linked receptor protein signaling pathway GO:0007167 179 0.041
embryo development ending in birth or egg hatching GO:0009792 152 0.040
programmed cell death GO:0012501 257 0.039
digestive tract development GO:0048565 149 0.039
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.038
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.038
regulation of multicellular organism growth GO:0040014 40 0.038
chemotaxis GO:0006935 249 0.037
establishment or maintenance of cell polarity GO:0007163 167 0.037
organonitrogen compound metabolic process GO:1901564 318 0.037
respiratory system development GO:0060541 213 0.036
proteolysis GO:0006508 192 0.036
positive regulation of multicellular organismal process GO:0051240 143 0.036
oxoacid metabolic process GO:0043436 103 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.034
lateral inhibition GO:0046331 206 0.034
vesicle mediated transport GO:0016192 381 0.034
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.034
chaeta morphogenesis GO:0008407 42 0.034
head development GO:0060322 135 0.033
cellular catabolic process GO:0044248 372 0.033
positive regulation of biosynthetic process GO:0009891 316 0.033
periodic partitioning GO:0007365 29 0.032
response to organic substance GO:0010033 284 0.032
positive regulation of rna metabolic process GO:0051254 271 0.032
muscle cell differentiation GO:0042692 103 0.032
imaginal disc derived appendage morphogenesis GO:0035114 395 0.032
wing disc morphogenesis GO:0007472 344 0.031
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.031
regulation of cell proliferation GO:0042127 163 0.031
macromolecule catabolic process GO:0009057 161 0.031
muscle organ development GO:0007517 127 0.030
camera type eye development GO:0043010 4 0.030
regulation of response to external stimulus GO:0032101 115 0.030
lipid metabolic process GO:0006629 121 0.029
negative regulation of organ growth GO:0046621 15 0.029
cardiovascular system development GO:0072358 82 0.029
regulation of epithelial cell proliferation GO:0050678 4 0.029
apoptotic process GO:0006915 159 0.029
positive regulation of transcription dna templated GO:0045893 266 0.029
regulation of organ growth GO:0046620 42 0.029
defense response to bacterium GO:0042742 178 0.028
gastrulation GO:0007369 70 0.028
organic substance transport GO:0071702 257 0.027
humoral immune response GO:0006959 117 0.027
muscle tissue development GO:0060537 30 0.027
axonogenesis GO:0007409 290 0.027
positive regulation of cell communication GO:0010647 250 0.027
peptidyl amino acid modification GO:0018193 105 0.027
cell cell signaling involved in cell fate commitment GO:0045168 210 0.026
tissue migration GO:0090130 155 0.026
death GO:0016265 284 0.026
carboxylic acid metabolic process GO:0019752 92 0.026
regulation of cell cycle GO:0051726 291 0.026
cellular protein catabolic process GO:0044257 83 0.025
striated muscle cell differentiation GO:0051146 90 0.025
organic acid metabolic process GO:0006082 103 0.025
epithelial cell differentiation GO:0030855 322 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.025
brain development GO:0007420 120 0.025
developmental cell growth GO:0048588 52 0.025
innate immune response GO:0045087 144 0.024
segmentation GO:0035282 207 0.024
cell division GO:0051301 248 0.024
rna splicing GO:0008380 83 0.024
tor signaling GO:0031929 32 0.024
cellular amine metabolic process GO:0044106 12 0.024
negative regulation of cellular metabolic process GO:0031324 382 0.024
negative regulation of rna metabolic process GO:0051253 251 0.024
cardiocyte differentiation GO:0035051 29 0.024
organic substance catabolic process GO:1901575 308 0.024
regulation of localization GO:0032879 275 0.023
cellular amino acid metabolic process GO:0006520 61 0.023
carbohydrate derivative biosynthetic process GO:1901137 85 0.022
dorsal ventral pattern formation GO:0009953 133 0.022
instar larval development GO:0002168 55 0.022
sterol homeostasis GO:0055092 4 0.022
regulation of female receptivity post mating GO:0046008 17 0.022
negative regulation of gene expression GO:0010629 387 0.022
positive regulation of gene expression GO:0010628 290 0.022
amine metabolic process GO:0009308 12 0.021
positive regulation of cell growth GO:0030307 19 0.021
ras protein signal transduction GO:0007265 88 0.021
digestive system development GO:0055123 149 0.021
multicellular organism growth GO:0035264 46 0.021
positive regulation of growth GO:0045927 75 0.021
forebrain development GO:0030900 2 0.021
compound eye morphogenesis GO:0001745 249 0.021
immune response regulating signaling pathway GO:0002764 2 0.021
copulation GO:0007620 26 0.020
response to hexose GO:0009746 3 0.020
striated muscle tissue development GO:0014706 27 0.020
regulation of catabolic process GO:0009894 170 0.020
cholesterol homeostasis GO:0042632 3 0.020
response to bacterium GO:0009617 198 0.020
transcription from rna polymerase ii promoter GO:0006366 368 0.020
regulation of cell size GO:0008361 63 0.020
positive regulation of canonical wnt signaling pathway GO:0090263 7 0.020
multi multicellular organism process GO:0044706 123 0.020
cell death GO:0008219 279 0.020
ubiquitin dependent protein catabolic process GO:0006511 78 0.020
muscle adaptation GO:0043500 1 0.020
gland development GO:0048732 191 0.020
regulation of immune system process GO:0002682 176 0.019
protein transport GO:0015031 155 0.019
spindle organization GO:0007051 253 0.019
regulation of immune response GO:0050776 118 0.019
positive regulation of developmental process GO:0051094 143 0.019
appendage morphogenesis GO:0035107 397 0.019
organophosphate metabolic process GO:0019637 195 0.019
embryonic pattern specification GO:0009880 174 0.019
developmental maturation GO:0021700 172 0.019
sensory organ morphogenesis GO:0090596 260 0.019
regulation of multi organism process GO:0043900 131 0.019
regulation of programmed cell death GO:0043067 152 0.019
negative regulation of signal transduction GO:0009968 206 0.019
regulation of anatomical structure morphogenesis GO:0022603 242 0.019
peptidyl proline hydroxylation GO:0019511 1 0.019
regulation of cellular amino acid metabolic process GO:0006521 0 0.018
negative regulation of female receptivity GO:0007621 14 0.018
epithelial cell development GO:0002064 274 0.018
establishment of localization in cell GO:0051649 402 0.018
positive regulation of cellular protein metabolic process GO:0032270 118 0.018
regulation of anatomical structure size GO:0090066 163 0.018
striated muscle cell development GO:0055002 50 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
response to lipopolysaccharide GO:0032496 4 0.018
response to monosaccharide GO:0034284 4 0.018
cellular response to dna damage stimulus GO:0006974 223 0.018
modification dependent protein catabolic process GO:0019941 78 0.018
kidney development GO:0001822 3 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.017
epithelium migration GO:0090132 148 0.017
connective tissue development GO:0061448 3 0.017
heart development GO:0007507 82 0.017
maintenance of location GO:0051235 73 0.017
response to radiation GO:0009314 155 0.017
negative regulation of female receptivity post mating GO:0045434 12 0.017
aging GO:0007568 143 0.017
dendrite morphogenesis GO:0048813 199 0.017
chromosome segregation GO:0007059 157 0.017
regulation of female receptivity GO:0045924 24 0.016
sperm competition GO:0046692 21 0.016
negative regulation of cell communication GO:0010648 223 0.016
compound eye photoreceptor cell differentiation GO:0001751 140 0.016
regulation of response to stress GO:0080134 200 0.016
single organism biosynthetic process GO:0044711 206 0.016
positive regulation of multicellular organism growth GO:0040018 21 0.016
multi organism reproductive behavior GO:0044705 121 0.016
central nervous system development GO:0007417 201 0.016
response to glucose GO:0009749 2 0.016
immune effector process GO:0002252 98 0.016
phosphorylation GO:0016310 294 0.016
regulation of cell death GO:0010941 173 0.016
circulatory system development GO:0072359 82 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
taxis GO:0042330 304 0.016
regulation of proteolysis GO:0030162 87 0.016
cell growth GO:0016049 108 0.016
wound healing GO:0042060 75 0.016
nucleocytoplasmic transport GO:0006913 72 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
small gtpase mediated signal transduction GO:0007264 88 0.015
rna processing GO:0006396 147 0.015
tube morphogenesis GO:0035239 191 0.015
immune response GO:0006955 246 0.015
peptide metabolic process GO:0006518 80 0.015
small molecule metabolic process GO:0044281 305 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
cell motility GO:0048870 251 0.015
regulation of response to biotic stimulus GO:0002831 63 0.015
protein phosphorylation GO:0006468 169 0.015
regulation of mitosis GO:0007088 56 0.015
macromolecular complex assembly GO:0065003 256 0.015
cation transport GO:0006812 110 0.015
negative regulation of programmed cell death GO:0043069 72 0.015
response to starvation GO:0042594 97 0.015
organelle fission GO:0048285 340 0.015
photoreceptor cell development GO:0042461 96 0.015
regulation of epithelial cell differentiation GO:0030856 4 0.015
eye photoreceptor cell development GO:0042462 81 0.014
response to other organism GO:0051707 293 0.014
nuclear transport GO:0051169 72 0.014
proteasomal protein catabolic process GO:0010498 59 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
protein modification by small protein conjugation or removal GO:0070647 106 0.014
dendrite development GO:0016358 204 0.014
eye development GO:0001654 323 0.014
regulation of transport GO:0051049 181 0.014
positive regulation of response to stimulus GO:0048584 323 0.014
response to endogenous stimulus GO:0009719 119 0.014
positive regulation of developmental growth GO:0048639 62 0.014
immune system process GO:0002376 347 0.014
regulation of protein catabolic process GO:0042176 55 0.014
negative regulation of epithelial cell proliferation GO:0050680 4 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
response to nutrient levels GO:0031667 114 0.014
negative regulation of cell death GO:0060548 81 0.014
limb development GO:0060173 1 0.014
cellular protein localization GO:0034613 160 0.014
intracellular signal transduction GO:0035556 300 0.014
positive regulation of signal transduction GO:0009967 223 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
hindbrain development GO:0030902 2 0.013
response to biotic stimulus GO:0009607 294 0.013
lipid localization GO:0010876 54 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.013
immune response activating signal transduction GO:0002757 2 0.013
cellular response to endogenous stimulus GO:0071495 80 0.013
actin cytoskeleton organization GO:0030036 206 0.013
peptidyl proline modification GO:0018208 3 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
regulation of protein modification process GO:0031399 112 0.013
anterior posterior pattern specification GO:0009952 136 0.013
regulation of protein metabolic process GO:0051246 256 0.013
lipid biosynthetic process GO:0008610 46 0.013
negative regulation of rna biosynthetic process GO:1902679 240 0.013
response to oxygen containing compound GO:1901700 200 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.013
protein processing GO:0016485 68 0.013
cellular macromolecule localization GO:0070727 220 0.013
response to ionizing radiation GO:0010212 32 0.013
regulation of immune effector process GO:0002697 52 0.013
cell maturation GO:0048469 144 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
skin development GO:0043588 65 0.013
positive regulation of immune response GO:0050778 63 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
ion transport GO:0006811 145 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
cellular lipid metabolic process GO:0044255 83 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
insemination GO:0007320 22 0.012
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
peptidyl tyrosine phosphorylation GO:0018108 24 0.012
protein maturation GO:0051604 71 0.012
positive regulation of neuron apoptotic process GO:0043525 1 0.012
limb morphogenesis GO:0035108 1 0.012
retina development in camera type eye GO:0060041 4 0.012
axon development GO:0061564 297 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
ameboidal type cell migration GO:0001667 151 0.012
jak stat cascade GO:0007259 49 0.012
cardiac muscle cell differentiation GO:0055007 4 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.012
hemopoiesis GO:0030097 46 0.012
antimicrobial humoral response GO:0019730 99 0.012
protein localization GO:0008104 284 0.012
positive regulation of catabolic process GO:0009896 105 0.012
anatomical structure homeostasis GO:0060249 97 0.012
intracellular protein transport GO:0006886 104 0.012
negative regulation of cell proliferation GO:0008285 69 0.012
negative regulation of cell cycle process GO:0010948 109 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
regulation of striated muscle tissue development GO:0016202 5 0.012
regulation of cell cycle process GO:0010564 181 0.012
regulation of cellular localization GO:0060341 136 0.012
segment specification GO:0007379 33 0.011
positive regulation of molecular function GO:0044093 136 0.011
g protein coupled receptor signaling pathway GO:0007186 136 0.011
response to alcohol GO:0097305 95 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
carbohydrate metabolic process GO:0005975 82 0.011
positive regulation of defense response GO:0031349 59 0.011
cell cycle phase transition GO:0044770 140 0.011
open tracheal system development GO:0007424 204 0.011
regulation of tor signaling GO:0032006 21 0.011
response to external biotic stimulus GO:0043207 293 0.011
axis specification GO:0009798 167 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.011
regulation of molecular function GO:0065009 217 0.011
negative regulation of signaling GO:0023057 219 0.011
nephron development GO:0072006 3 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
single organism intracellular transport GO:1902582 207 0.011
rna transport GO:0050658 46 0.011
cardiac muscle tissue development GO:0048738 9 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
posttranscriptional regulation of gene expression GO:0010608 145 0.011
chromosome organization GO:0051276 360 0.011
somatic muscle development GO:0007525 66 0.011
spindle elongation GO:0051231 83 0.011
multi organism behavior GO:0051705 175 0.011
antimicrobial peptide production GO:0002775 46 0.011
lipid homeostasis GO:0055088 33 0.011
cellular response to hormone stimulus GO:0032870 44 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
purine containing compound catabolic process GO:0072523 112 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
regulation of rna splicing GO:0043484 69 0.010
regulation of phosphorus metabolic process GO:0051174 210 0.010
renal system development GO:0072001 72 0.010
establishment of planar polarity GO:0001736 87 0.010
cellular response to biotic stimulus GO:0071216 4 0.010
dna metabolic process GO:0006259 227 0.010
camera type eye morphogenesis GO:0048593 2 0.010
regulation of cell growth GO:0001558 43 0.010
hormone catabolic process GO:0042447 3 0.010
gland morphogenesis GO:0022612 145 0.010
salivary gland development GO:0007431 162 0.010
morphogenesis of follicular epithelium GO:0016333 36 0.010
actin filament organization GO:0007015 126 0.010
cellular response to chemical stimulus GO:0070887 199 0.010
compound eye development GO:0048749 307 0.010
response to copper ion GO:0046688 4 0.010
eye photoreceptor cell differentiation GO:0001754 145 0.010
regulation of apoptotic process GO:0042981 130 0.010
mapk cascade GO:0000165 107 0.010

Orct2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
disease of metabolism DOID:0014667 0 0.022
inherited metabolic disorder DOID:655 0 0.022
nervous system disease DOID:863 0 0.011