Drosophila melanogaster

10 known processes

Alas (Dmel_CG3017)

Aminolevulinate synthase

(Aliases: CG3017,alas,Dmel\CG3017)

Alas biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organonitrogen compound metabolic process GO:1901564 318 0.094
small molecule metabolic process GO:0044281 305 0.074
spindle organization GO:0007051 253 0.067
regionalization GO:0003002 416 0.065
nucleotide metabolic process GO:0009117 161 0.064
carboxylic acid metabolic process GO:0019752 92 0.061
nucleoside monophosphate metabolic process GO:0009123 52 0.058
mitotic spindle organization GO:0007052 220 0.057
ribose phosphate metabolic process GO:0019693 145 0.052
oxidation reduction process GO:0055114 123 0.051
organelle fusion GO:0048284 46 0.049
cellular respiration GO:0045333 26 0.048
glycosyl compound metabolic process GO:1901657 127 0.045
disaccharide transport GO:0015766 2 0.044
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.043
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.042
ribonucleotide metabolic process GO:0009259 145 0.040
response to ethanol GO:0045471 59 0.040
nucleobase containing compound catabolic process GO:0034655 165 0.040
ribonucleoside metabolic process GO:0009119 127 0.038
nucleoside metabolic process GO:0009116 127 0.038
nucleoside triphosphate metabolic process GO:0009141 120 0.037
meiosis i GO:0007127 59 0.035
heterocycle catabolic process GO:0046700 166 0.035
carbohydrate derivative metabolic process GO:1901135 217 0.034
purine ribonucleotide metabolic process GO:0009150 145 0.033
purine containing compound metabolic process GO:0072521 155 0.032
purine nucleoside metabolic process GO:0042278 127 0.032
nuclear division GO:0000280 332 0.031
ribonucleoside triphosphate metabolic process GO:0009199 119 0.030
organelle fission GO:0048285 340 0.030
mitochondrion organization GO:0007005 65 0.030
nucleoside phosphate metabolic process GO:0006753 162 0.029
aggressive behavior GO:0002118 63 0.029
purine nucleoside monophosphate metabolic process GO:0009126 50 0.029
atp metabolic process GO:0046034 49 0.028
organic cyclic compound catabolic process GO:1901361 168 0.027
protein processing GO:0016485 68 0.027
oxidoreduction coenzyme metabolic process GO:0006733 2 0.027
negative regulation of rna metabolic process GO:0051253 251 0.026
organic substance catabolic process GO:1901575 308 0.026
nucleobase containing small molecule metabolic process GO:0055086 174 0.026
body morphogenesis GO:0010171 2 0.026
phagocytosis GO:0006909 215 0.025
cellular catabolic process GO:0044248 372 0.025
translation GO:0006412 69 0.024
negative regulation of cellular component organization GO:0051129 108 0.024
purine ribonucleoside metabolic process GO:0046128 127 0.024
response to organic substance GO:0010033 284 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.024
membrane fusion GO:0061025 42 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.023
single organism membrane fusion GO:0044801 42 0.023
growth GO:0040007 359 0.022
nicotinamide nucleotide metabolic process GO:0046496 2 0.022
regulation of response to stress GO:0080134 200 0.021
vesicle mediated transport GO:0016192 381 0.021
negative regulation of gene expression GO:0010629 387 0.021
homeostatic process GO:0042592 199 0.021
regulation of organelle organization GO:0033043 196 0.021
single organism catabolic process GO:0044712 228 0.021
aromatic compound catabolic process GO:0019439 166 0.021
negative regulation of signal transduction GO:0009968 206 0.021
mitotic spindle elongation GO:0000022 81 0.020
cell cell signaling involved in cell fate commitment GO:0045168 210 0.020
protein maturation GO:0051604 71 0.020
organophosphate metabolic process GO:0019637 195 0.019
peptide metabolic process GO:0006518 80 0.019
meiotic nuclear division GO:0007126 151 0.018
compound eye development GO:0048749 307 0.018
gene silencing by rna GO:0031047 57 0.018
oligosaccharide transport GO:0015772 2 0.017
protein complex biogenesis GO:0070271 201 0.017
organonitrogen compound catabolic process GO:1901565 128 0.017
negative regulation of cellular metabolic process GO:0031324 382 0.017
positive regulation of immune system process GO:0002684 68 0.017
meiotic cell cycle GO:0051321 171 0.017
single organism cellular localization GO:1902580 180 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
organophosphate catabolic process GO:0046434 112 0.016
ribonucleotide catabolic process GO:0009261 109 0.016
cellular amide metabolic process GO:0043603 80 0.016
oxidative phosphorylation GO:0006119 9 0.015
single organism membrane organization GO:0044802 93 0.015
oxoacid metabolic process GO:0043436 103 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
negative regulation of transcription dna templated GO:0045892 237 0.015
cytoplasmic translation GO:0002181 0 0.015
energy derivation by oxidation of organic compounds GO:0015980 32 0.015
mitotic nuclear division GO:0007067 213 0.015
response to temperature stimulus GO:0009266 106 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.015
cell death GO:0008219 279 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.014
pyridine nucleotide metabolic process GO:0019362 2 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
response to alcohol GO:0097305 95 0.014
cellular macromolecular complex assembly GO:0034622 153 0.014
cell cycle phase transition GO:0044770 140 0.014
ion homeostasis GO:0050801 55 0.014
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
nucleoside triphosphate catabolic process GO:0009143 108 0.013
dna metabolic process GO:0006259 227 0.013
response to abiotic stimulus GO:0009628 341 0.013
Human
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
pyridine containing compound metabolic process GO:0072524 3 0.013
lateral inhibition GO:0046331 206 0.013
cellular ion homeostasis GO:0006873 39 0.013
citrate metabolic process GO:0006101 0 0.013
appendage morphogenesis GO:0035107 397 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.013
purine nucleotide catabolic process GO:0006195 109 0.013
cell aging GO:0007569 2 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
anion homeostasis GO:0055081 3 0.012
regulation of anatomical structure size GO:0090066 163 0.012
regulation of cell cycle GO:0051726 291 0.012
digestive tract development GO:0048565 149 0.012
regulation of growth GO:0040008 233 0.012
gene silencing GO:0016458 138 0.012
negative regulation of rna biosynthetic process GO:1902679 240 0.012
ribonucleoside monophosphate metabolic process GO:0009161 51 0.012
response to heat GO:0009408 63 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
aging GO:0007568 143 0.012
positive regulation of defense response GO:0031349 59 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
death GO:0016265 284 0.012
membrane organization GO:0061024 112 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
negative regulation of developmental process GO:0051093 201 0.012
regulation of defense response GO:0031347 102 0.011
nucleotide catabolic process GO:0009166 109 0.011
regulation of cell death GO:0010941 173 0.011
protein transport GO:0015031 155 0.011
regulation of cell cycle process GO:0010564 181 0.011
protein complex assembly GO:0006461 200 0.011
regulation of molecular function GO:0065009 217 0.011
response to organophosphorus GO:0046683 2 0.011
response to bacterium GO:0009617 198 0.011
defense response to gram negative bacterium GO:0050829 94 0.011
organic acid metabolic process GO:0006082 103 0.011
purine containing compound catabolic process GO:0072523 112 0.011
response to oxygen levels GO:0070482 59 0.011
Human
maintenance of location GO:0051235 73 0.011
immune response GO:0006955 246 0.011
negative regulation of response to stimulus GO:0048585 258 0.011
trehalose transport GO:0015771 1 0.011
defense response GO:0006952 300 0.011
neurological system process GO:0050877 358 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
eye morphogenesis GO:0048592 260 0.011
cellular homeostasis GO:0019725 80 0.010
cell division GO:0051301 248 0.010
lipid storage GO:0019915 38 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.010
regulation of cellular amine metabolic process GO:0033238 3 0.010
protein depolymerization GO:0051261 31 0.010
negative regulation of signaling GO:0023057 219 0.010
chromosome organization GO:0051276 360 0.010
translational elongation GO:0006414 4 0.010
proteolysis GO:0006508 192 0.010
cellular protein modification process GO:0006464 438 0.010

Alas disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.088
Human
nervous system disease DOID:863 0 0.037
disease of metabolism DOID:0014667 0 0.022
Human
sensory system disease DOID:0050155 0 0.015
disease of cellular proliferation DOID:14566 0 0.014
organ system cancer DOID:0050686 0 0.012
cancer DOID:162 0 0.012
central nervous system disease DOID:331 0 0.012
eye disease DOID:5614 0 0.011
eye and adnexa disease DOID:1492 0 0.011
musculoskeletal system disease DOID:17 0 0.011
connective tissue disease DOID:65 0 0.011
neurodegenerative disease DOID:1289 0 0.010